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Elizabeth J. Shpall
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Journal Articles

Antibiotic-induced loss of gut microbiome metabolic output correlates with clinical responses to CAR T-cell therapy

Clinical Trials & Observations
Rishika Prasad, Abdur Rehman, Lubna Rehman, Faezeh Darbaniyan, Viktoria Blumenberg, Maria-Luisa Schubert, Uria Mor, Eli Zamir, Sabine Schmidt, Tomo Hayase, Chia-Chi Chang, Lauren McDaniel, Ivonne Flores, Paolo Strati, Ranjit Nair, Dai Chihara, Luis E. Fayad, Sairah Ahmed, Swaminathan P. Iyer, Michael Wang, Preetesh Jain, Loretta J. Nastoupil, Jason Westin, Reetakshi Arora, Joel Turner, Fareed Khawaja, Ranran Wu, Jennifer B. Dennison, Meghan Menges, Melanie Hidalgo-Vargas, Kayla Reid, Marco L. Davila, Peter Dreger, Felix Korell, Anita Schmitt, Mark R. Tanner, Richard E. Champlin, Christopher R. Flowers, Elizabeth J. Shpall, Samir Hanash, Sattva S. Neelapu, Michael Schmitt, Marion Subklewe, Johannes Francois-Fahrmann, C. K. Stein-Thoeringer, Eran Elinav, Michael D. Jain, Eiko Hayase, Robert R. Jenq, Neeraj Y. Saini
Journal: Blood
Blood (2025) 145 (8): 823–839.
https://doi.org/10.1182/blood.2024025366
Published: 2025
Includes: Supplemental data
Journal Articles

Phase 1b/2 Study of Decitabine and Venetoclax in Combination with the Targeted Mutant IDH1 Inhibitor Olutasidenib for Patients with Relapsed/Refractory AML, High Risk MDS, or Newly Diagnosed AML Not Eligible for Chemotherapy with an IDH1 Mutation

Courtney D. DiNardo, Kelly S. Chien, Jillian Mullin, Danielle Hammond, Jeremy Ramdial, Tapan M. Kadia, Fadi G. Haddad, Musa Yilmaz, Koji Sasaki, Ghayas C. Issa, Koichi Takahashi, Elizabeth J. Shpall, Farhad Ravandi, Naval Daver, Hagop Kantarjian
Journal: Blood
Blood (2024) 144 (Supplement 1): 1527.2.
https://doi.org/10.1182/blood-2024-208771
Published: 2024
Journal Articles

Fractionated Busulfan, Fludarabine and Thiotepa Myeloablative Conditioning to Improve Transplant Outcomes for Myelofibrosis

Samer A. Srour, Rima M. Saliba, Jeremy Ramdial, Portia Smallbone, Jin S. Im, Amanda L. Olson, Crystal Carmicheal Kusy, Betul Oran, George Chen, Muzaffar H. Qazilbash, Partow Kebriaei, Chitra Hosing, Issa F. Khouri, Amin M. Alousi, Qaiser Bashir, David Marin, Yago Nieto, Elizabeth J. Shpall, Richard E. Champlin, Uday Popat
Journal: Blood
Blood (2024) 144 (Supplement 1): 3514.
https://doi.org/10.1182/blood-2024-211371
Published: 2024
Journal Articles

Addition of Inotuzumab Ozogamicin to Melphalan Plus Fludarabine Reduced-Intensity Conditioning Regimen of Allogeneic Transplantation in Patients with Acute Lymphoblastic Leukemia and Aggressive Lymphoid Malignancies: A Phase II Prospective Trial

Issa F. Khouri, Hagop M. Kantarjian, Alison M. Gulbis, Manuel M. Christopher, Fadi G. Haddad, Hussein A. Abbas, Bofei Wang, Koji Sasaki, Nitin Jain, Tapan M. Kadia, David Marin, Elizabeth J. Shpall, Gabriela Rondon, Hind Rafei, Jeremy Ramdial, Jin S. Im, Partow Kebriaei, Wei Qiao, Richard E. Champlin, Elias Jabbour
Journal: Blood
Blood (2024) 144 (Supplement 1): 2124.
https://doi.org/10.1182/blood-2024-203864
Published: 2024
Journal Articles

Myeloablative Fractionated Busulfan, Fludarabine, Cladribine, Thiotepa and Venetoclax (Cladillac) Conditioning Regimen for Very High-Risk AML/MDS: A Phase 2 Trial

Uday Popat, Roland L. Bassett, Amin M. Alousi, Gheath Alatrash, Yosra M. Aljawai, Qaiser Bashir, George Chen, Warren B. Fingrut, Chitra Hosing, Jin S. Im, Partow Kebriaei, David Marin, Yago Nieto, Amanda L. Olson, Betul Oran, Muzaffar H. Qazilbash, Jeremy Ramdial, Neeraj Y. Saini, Portia Smallbone, Samer A. Srour, Benigno C. Valdez, Richard E. Champlin, Borje S. Andersson, Elizabeth J. Shpall
Journal: Blood
Blood (2024) 144 (Supplement 1): 506.
https://doi.org/10.1182/blood-2024-203338
Published: 2024
Journal Articles

Impact of Ethnicity on Long Term Outcomes of High-Dose Chemotherapy and Upfront Autologous Hematopoietic Stem Cell Transplantation in Patients with Multiple Myeloma

Frances N. Cervoni Curet, Roland L. Bassett, Oren Pasvolsky, Abdullah Faisal Deen, Mark R. Tanner, Qaiser Bashir, Samer A. Srour, Neeraj Y. Saini, Jeremy Ramdial, Yago Nieto, Hans C. Lee, Krina K. Patel, Partow Kebriaei, Warren B. Fingrut, Portia Smallbone, Melody R. Becnel, Mahmoud R. Gaballa, Sheeba K. Thomas, J Christine Ye, Robert Z. Orlowski, Richard E. Champlin, Elizabeth J. Shpall, Muzaffar H. Qazilbash
Journal: Blood
Blood (2024) 144 (Supplement 1): 5154.
https://doi.org/10.1182/blood-2024-203824
Published: 2024
Journal Articles

Phase II Clinical Trial of “Off-the-Shelf” NK Cells with Allogeneic Stem Cell Transplantation in Patients with High-Risk Myeloid Malignancies

Jeremy Ramdial, Lorlyn Clemente, Pinaki Banerjee, Bouthaina S. Dabaja, Gheath Al-Atrash, Amin M. Alousi, Betul Oran, Uday Popat, Jin S. Im, Samer A. Srour, George Chen, Partow Kebriaei, Chitra Hosing, David Marin, Katayoun Rezvani, Elizabeth J. Shpall, Richard E. Champlin
Journal: Blood
Blood (2024) 144 (Supplement 1): 4841.
https://doi.org/10.1182/blood-2024-211389
Published: 2024
Journal Articles

Cord-Derived Invariant Natural Killer T Cells As Novel Cell Therapy to Improve the Outcome of Hematopoietic Stem Cell Transplantation

Abel Trujillo-Ocampo, Maison Grefe, Pamella Borges, Jelita Clinton, Hong He, Dan Li, Ling Yu, Martiela Vaz de Freitas, Lisa St. John, Karen Clise-Dwyer, Gheath Alatrash, Dinler Amaral Antues, Qing Ma, Jeffrey J. Molldrem, Elizabeth J. Shpall, Jin S. Im
Journal: Blood
Blood (2024) 144 (Supplement 1): 4818.
https://doi.org/10.1182/blood-2024-210168
Published: 2024
Journal Articles

Predictors of Graft-Versus-Host Disease with Post-Transplant Cyclophosphamide

Rima M. Saliba, Yosra M. Aljawai, Amin M. Alousi, Betul Oran, Uday Popat, Richard E. Champlin, Elizabeth J. Shpall
Journal: Blood
Blood (2024) 144 (Supplement 1): 4890.
https://doi.org/10.1182/blood-2024-210660
Published: 2024
Journal Articles

Treatment in Clinical Trials Could Potentially Overcome the Disparity in Outcomes of Patients with Acute Myeloid Leukemia from Disadvantaged Neighborhoods

Mahesh Swaminathan, Hussein A. Abbas, Guillermo Garcia-Manero, Naval Daver, Tapan M. Kadia, Courtney D. DiNardo, Gautam Borthakur, Elias Jabbour, Naveen Pemmaraju, Yesid Alvarado Valero, Maro Ohanian, Nitin Jain, Nicholas J. Short, Prithviraj Bose, Koichi Takahashi, Hyunsoo Hwang, Xuelin Huang, Paul Edelkamp, Jr., Sherry Pierce, Uday Popat, Elizabeth J. Shpall, Richard E. Champlin, Hagop M. Kantarjian, Farhad Ravandi
Journal: Blood
Blood (2024) 144 (Supplement 1): 3817.
https://doi.org/10.1182/blood-2024-210779
Published: 2024
Journal Articles

Outcomes of Patients with Treated Secondary AML: A High Risk Subtype of AML Arising from Previously Treated Myeloid Neoplasms That Warrants an Independent Prognostic Designation

Jayastu Senapati, Hagop M. Kantarjian, Guillermo Garcia-Manero, Nicholas J. Short, Fadi G. Haddad, Naval Daver, Courtney D. DiNardo, Gautam Borthakur, Joseph E. Jabbour, Naveen Pemmaraju, Amin M. Alousi, Elizabeth J. Shpall, Alexandre Bazinet, Kelly S. Chien, Danielle Hammond, Sherry Pierce, Farhad Ravandi, Tapan M. Kadia
Journal: Blood
Blood (2024) 144 (Supplement 1): 4251.
https://doi.org/10.1182/blood-2024-208121
Published: 2024
Journal Articles

Imaging Activated Innate Immune Myeloid Cells in Immune Effector Cell-Associated Neurotoxicity Syndrome (ICANS) Following CAR T-Cell Therapy

Ajlan Al Zaki, Margie Sutton, Abdur Rehman, Cao Cuong Le, Seth Gammon, Arianna Napoli, Ping Yang, Neeraj Y. Saini, Sairah Ahmed, Ghayas C. Issa, Partow Kebriaei, Michael Davies, Elizabeth J. Shpall, Jeena Varghese, Lesley Flynt, Sattva S. Neelapu, David Piwnica-Worms
Journal: Blood
Blood (2024) 144 (Supplement 1): 3428.
https://doi.org/10.1182/blood-2024-211204
Published: 2024
Journal Articles

Peripheral Blood CAR T-Cell Level Using a Clia-Validated Assay Is Prognostic for Treatment Response and Icans in Large B-Cell Lymphoma

Anath Lionel, Naishu Kui, Ryan Sun, Eslam Aboismail, Sanjit Om Tewari, Ajlan Al Zaki, Sushanth Gouni, Preetesh Jain, Dai Chihara, Swaminathan P Iyer, Michael Wang, Ranjit Nair, Luis Enrique Malpica Castillo, Hun Ju Lee, Chijioke Nze, Luis E. Fayad, Frederick Hagemeister, Maria Alma Rodriguez, Amy A. Ayers, Cristina Gutierrez, Gabriela Rondon, Fareed Khawaja, Partow Kebriaei, Elizabeth J. Shpall, Christopher R. Flowers, Jason R. Westin, Paolo Strati, Wei WANG, Sa A. Wang, Sairah Ahmed, Sattva S. Neelapu
Journal: Blood
Blood (2024) 144 (Supplement 1): 3001.
https://doi.org/10.1182/blood-2024-208300
Published: 2024
Journal Articles

Impact of Age on Autologous Stem Cell Transplantation Outcomes for AL Amyloidosis

Sophiya S Sami, Qaiser Bashir, Neeraj Y. Saini, Yosra M. Aljawai, Chitra Hosing, Uday Popat, Melody R. Becnel, Gregory P. Kaufman, Sheeba K. Thomas, Donna M. Weber, Robert Z. Orlowski, Richard E. Champlin, Elizabeth J. Shpall, Muzaffar H. Qazilbash, Samer A. Srour
Journal: Blood
Blood (2024) 144 (Supplement 1): 1923.
https://doi.org/10.1182/blood-2024-211495
Published: 2024
Journal Articles

Predictive Factors for Transplant Outcomes of Cardiac AL Amyloidosis

Abdullah Faisal Deen, Qaiser Bashir, Neeraj Y. Saini, Yosra M. Aljawai, Chitra Hosing, Uday Popat, Melody R. Becnel, Gregory P. Kaufman, Sheeba K. Thomas, Donna M. Weber, Robert Z. Orlowski, Elizabeth J. Shpall, Richard E. Champlin, Muzaffar H. Qazilbash, Samer A. Srour
Journal: Blood
Blood (2024) 144 (Supplement 1): 1922.
https://doi.org/10.1182/blood-2024-211408
Published: 2024
Journal Articles

Clonal Origin of Therapy-Related Myeloid Neoplasms after Autologous Stem Cell Transplant

Hidetaka Uryu, Koichi Saeki, Hiroshi Haeno, Chiraag Kapadia, Ken Furudate, Jyoti Nangalia, Michael Spencer Chapman, Li Zhao, Joanne Hsu, Chong Zhao, Shujuan Chen, Tomoyuki Tanaka, Zongrui Li, Hui Yang, Courtney D. DiNardo, Naval Daver, Naveen Pemmaraju, Nitin Jain, Farhad Ravandi, Jianhua Zhang, Xingzhi Song, Erika Thompson, Hongli Tang, Latasha Little, Curtis Gumbs, Robert Z. Orlowski, Muzaffar H. Qazilbash, Kapil N. Bhalla, Simona Colla, Hagop M. Kantarjian, Rashmi Kanagal-Shamanna, Carlos E. Bueso-Ramos, Daisuke Nakada, Jeffrey J. Molldrem, Gheath Alatrash, Andrew Futreal, Elizabeth J. Shpall, Margaret Goodell, Guillermo Garcia-Manero, Koichi Takahashi
Journal: Blood
Blood (2024) 144 (Supplement 1): 346.
https://doi.org/10.1182/blood-2024-208106
Published: 2024
Journal Articles

Large Scale Manufacturing of GMP Grade Cord Blood Derived Megakaryocytes for Chemotherapy Induced Thrombocytopenia

Hila Shaim, Mayela Carolina Mendt, Hani Lee, Bijender Kumar, Min Soon Cho, Alejandro Ramirez, Indreshpal Kaur, Torey Mallory, Arthur Aquino, Patrick Olivares, Cody Hensley, Kendall Friedman, Mecit Kaplan, Ana K. Nunez Cortes, Jeff Wilson, Jeremy Ramdial, Uday Popat, Vahid Afshar-Kharghan, Katayoun Rezvani, Elizabeth J. Shpall
Journal: Blood
Blood (2024) 144 (Supplement 1): 3926.
https://doi.org/10.1182/blood-2024-209206
Published: 2024
Journal Articles

Impact of Pre-Existing Mental Health Disorders (MHD) on CAR T-Cell Therapy Outcomes in Patients with Large B-Cell Lymphoma

Sushanth Gouni, Anath Lionel, Lei Feng, Charles Gaulin, Tejaswini Reddy, Amrit S. Gonugunta, Victoria Chu, Taylor Hopper, Amy A. Ayers, Inimfon Jackson, Ajlan Al Zaki, Michelle A.T. Hildebrandt, Loretta Nastoupil, Dai Chihara, Chijioke Nze, Jeremy Ramdial, Elizabeth J. Shpall, Jason R. Westin, Christopher R. Flowers, Paolo Strati, Sattva S. Neelapu, Rachel Lynn, Sairah Ahmed
Journal: Blood
Blood (2024) 144 (Supplement 1): 4508.
https://doi.org/10.1182/blood-2024-198053
Published: 2024
Journal Articles

Impact of Pre-Treatment Liver-Related Factors on Clinical Outcomes after CAR T-Cell Therapy for Lymphoma

Anath Lionel, Sushanth Gouni, Lei Feng, Charles Gaulin, Amrit S. Gonugunta, Turcin Saridogan, Michelly Abreu, Jaimole Varghese, Karla Ow, Minifrida Santiago, Ajlan Al Zaki, Sherry Adkins, Amy A. Ayers, Misha Hawkins, Partow Kebriaei, Elizabeth J. Shpall, Swaminathan P Iyer, Preetesh Jain, Michael Wang, Christopher R. Flowers, Jeremy Ramdial, Loretta Nastoupil, Jason R. Westin, Paolo Strati, Sattva S. Neelapu, Deyali Chatterjee, Sairah Ahmed
Journal: Blood
Blood (2024) 144 (Supplement 1): 4506.
https://doi.org/10.1182/blood-2024-207616
Published: 2024
Journal Articles

HLA-DPB1 Mismatches and the Impact on Unrelated Donor Transplant Outcomes with the Use of Post-Transplant Cyclophosphamide

Portia Smallbone, Kai Cao, Rima M. Saliba, Michele Alvarez, Warren B Fingrut, Yosra Aljawai, Amanda L. Olson, Amin M. Alousi, George Chen, Jeremy Ramdial, Richard E. Champlin, Elizabeth J. Shpall, Betul Oran
Journal: Blood
Blood (2024) 144 (Supplement 1): 4937.
https://doi.org/10.1182/blood-2024-200238
Published: 2024