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Sattva S. Neelapu
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Journal Articles

Blunted CD40-responsive enhancer activation in CREBBP-mutant lymphomas can be restored by enforced CD4 T-cell engagement

Haopeng Yang, Wenchao Zhang, Vida Ravanmehr, Guiling Cui, Kevin Bowman, Ruidong Chen, Jared Henderson, Shyanne Ruby Lockman, Estela Rojas, Ashley Lauren Wilson, Sydney Parsons, Ariel Mechaly, Leslie Regad, Ahmed Haouz, Christopher R. Flowers, Sattva S. Neelapu, Loretta J. Nastoupil, Richard Eric Davis, Qing Deng, Fernando Rodrigues Lima, Michael R Green
Journal: Blood
Blood blood.2024026664.
https://doi.org/10.1182/blood.2024026664
Published: 2025
Includes: Supplemental data
Journal Articles

Antibiotic-induced loss of gut microbiome metabolic output correlates with clinical responses to CAR T-cell therapy

Clinical Trials & Observations
Rishika Prasad, Abdur Rehman, Lubna Rehman, Faezeh Darbaniyan, Viktoria Blumenberg, Maria-Luisa Schubert, Uria Mor, Eli Zamir, Sabine Schmidt, Tomo Hayase, Chia-Chi Chang, Lauren McDaniel, Ivonne Flores, Paolo Strati, Ranjit Nair, Dai Chihara, Luis E. Fayad, Sairah Ahmed, Swaminathan P. Iyer, Michael Wang, Preetesh Jain, Loretta J. Nastoupil, Jason Westin, Reetakshi Arora, Joel Turner, Fareed Khawaja, Ranran Wu, Jennifer B. Dennison, Meghan Menges, Melanie Hidalgo-Vargas, Kayla Reid, Marco L. Davila, Peter Dreger, Felix Korell, Anita Schmitt, Mark R. Tanner, Richard E. Champlin, Christopher R. Flowers, Elizabeth J. Shpall, Samir Hanash, Sattva S. Neelapu, Michael Schmitt, Marion Subklewe, Johannes Francois-Fahrmann, C. K. Stein-Thoeringer, Eran Elinav, Michael D. Jain, Eiko Hayase, Robert R. Jenq, Neeraj Y. Saini
Journal: Blood
Blood (2025) 145 (8): 823–839.
https://doi.org/10.1182/blood.2024025366
Published: 2025
Includes: Supplemental data
Journal Articles

Three-year follow-up analysis of first-line axicabtagene ciloleucel in high-risk large B-cell lymphoma (ZUMA-12)

Clinical Trials & Observations
Julio C. Chavez, Michael Dickinson, Javier Munoz, Matthew L. Ulrickson, Catherine Thieblemont, Olalekan O. Oluwole, Alex F. Herrera, Chaitra Ujjani, Yi Lin, Peter A. Riedell, Natasha Kekre, Sven de Vos, Jacob Wullf, Chad M. Williams, Joshua Winters, Ioana Magdalena Kloos, Dr, Hairong Xu, Sattva S. Neelapu
Journal: Blood
Blood blood.2024027347.
https://doi.org/10.1182/blood.2024027347
Published: 2025
Includes: Supplemental data
Journal Articles

Personalized Neoantigen Peptide Vaccine with or without Lenalidomide for Patients with Intermediate or High Risk Smoldering Multiple Myeloma (SMM) to Prevent Progression to Multiple Myeloma (MM)

Krina K. Patel, Elisabet E. Manasanch, Hans C. Lee, J Christine Ye, Sheeba K. Thomas, Donna M. Weber, Melody R. Becnel, Mahmoud R. Gaballa, Hima Bansal, Zuzana Berkova, Sattva S. Neelapu, Cara L Haymaker, Minghao Dang, Linghua Wang, Greg Lizee, Robert Z. Orlowski
Journal: Blood
Blood (2024) 144 (Supplement 1): 4737.
https://doi.org/10.1182/blood-2024-205663
Published: 2024
Journal Articles

Radiation Therapy and Monocyte Activation in Large B-Cell Lymphoma Patients Treated with CAR T-Cell Therapy

Penny Q. Fang, Susan Y. Wu, Jillian R. Gunther, Alena Frank, Pavel Zemskiy, Aleksandr Zaitsev, Evgenii S Bolshakov, Anastasiya Terenteva, Krystle Nomie, Michelly Abreu, Karla Ow, Minifrida Santiago, Jaimole Varghese, Amy Ayers, Jared Henderson, Sairah Ahmed, Jason R. Westin, Christopher R. Flowers, Sattva S. Neelapu, Bouthaina S. Dabaja, Chelsea C. Pinnix, Paolo Strati
Journal: Blood
Blood (2024) 144 (Supplement 1): 4377.
https://doi.org/10.1182/blood-2024-203844
Published: 2024
Journal Articles

Imaging Activated Innate Immune Myeloid Cells in Immune Effector Cell-Associated Neurotoxicity Syndrome (ICANS) Following CAR T-Cell Therapy

Ajlan Al Zaki, Margie Sutton, Abdur Rehman, Cao Cuong Le, Seth Gammon, Arianna Napoli, Ping Yang, Neeraj Y. Saini, Sairah Ahmed, Ghayas C. Issa, Partow Kebriaei, Michael Davies, Elizabeth J. Shpall, Jeena Varghese, Lesley Flynt, Sattva S. Neelapu, David Piwnica-Worms
Journal: Blood
Blood (2024) 144 (Supplement 1): 3428.
https://doi.org/10.1182/blood-2024-211204
Published: 2024
Journal Articles

Peripheral Blood CAR T-Cell Level Using a Clia-Validated Assay Is Prognostic for Treatment Response and Icans in Large B-Cell Lymphoma

Anath Lionel, Naishu Kui, Ryan Sun, Eslam Aboismail, Sanjit Om Tewari, Ajlan Al Zaki, Sushanth Gouni, Preetesh Jain, Dai Chihara, Swaminathan P Iyer, Michael Wang, Ranjit Nair, Luis Enrique Malpica Castillo, Hun Ju Lee, Chijioke Nze, Luis E. Fayad, Frederick Hagemeister, Maria Alma Rodriguez, Amy A. Ayers, Cristina Gutierrez, Gabriela Rondon, Fareed Khawaja, Partow Kebriaei, Elizabeth J. Shpall, Christopher R. Flowers, Jason R. Westin, Paolo Strati, Wei WANG, Sa A. Wang, Sairah Ahmed, Sattva S. Neelapu
Journal: Blood
Blood (2024) 144 (Supplement 1): 3001.
https://doi.org/10.1182/blood-2024-208300
Published: 2024
Journal Articles

Impact of Inflammation, Tumor and Product Attributes on Clinical Outcomes in Patients with Relapsed/Refractory Follicular Lymphoma Treated with Axicabtagene Ciloleucel

Soumya Poddar, Jiali Yan, Gayatri Tiwari, Darawan Rinchai, Wangshu Zhang, Justin Budka, Weixin Peng, Shruti Salunkhe, Madison Davis, Qinghua Song, Sara Beygi, Harry Miao, Mike Mattie, Rhine Shen, Caron A. Jacobson, Davide Bedognetti, Simone Filosto, Sattva S. Neelapu
Journal: Blood
Blood (2024) 144 (Supplement 1): 4368.
https://doi.org/10.1182/blood-2024-211139
Published: 2024
Journal Articles

Impact of Pre-Existing Mental Health Disorders (MHD) on CAR T-Cell Therapy Outcomes in Patients with Large B-Cell Lymphoma

Sushanth Gouni, Anath Lionel, Lei Feng, Charles Gaulin, Tejaswini Reddy, Amrit S. Gonugunta, Victoria Chu, Taylor Hopper, Amy A. Ayers, Inimfon Jackson, Ajlan Al Zaki, Michelle A.T. Hildebrandt, Loretta Nastoupil, Dai Chihara, Chijioke Nze, Jeremy Ramdial, Elizabeth J. Shpall, Jason R. Westin, Christopher R. Flowers, Paolo Strati, Sattva S. Neelapu, Rachel Lynn, Sairah Ahmed
Journal: Blood
Blood (2024) 144 (Supplement 1): 4508.
https://doi.org/10.1182/blood-2024-198053
Published: 2024
Journal Articles

Impact of Pre-Treatment Liver-Related Factors on Clinical Outcomes after CAR T-Cell Therapy for Lymphoma

Anath Lionel, Sushanth Gouni, Lei Feng, Charles Gaulin, Amrit S. Gonugunta, Turcin Saridogan, Michelly Abreu, Jaimole Varghese, Karla Ow, Minifrida Santiago, Ajlan Al Zaki, Sherry Adkins, Amy A. Ayers, Misha Hawkins, Partow Kebriaei, Elizabeth J. Shpall, Swaminathan P Iyer, Preetesh Jain, Michael Wang, Christopher R. Flowers, Jeremy Ramdial, Loretta Nastoupil, Jason R. Westin, Paolo Strati, Sattva S. Neelapu, Deyali Chatterjee, Sairah Ahmed
Journal: Blood
Blood (2024) 144 (Supplement 1): 4506.
https://doi.org/10.1182/blood-2024-207616
Published: 2024
Journal Articles

Identifying the Barriers of Clinical Trial Access after CAR T-Cell Therapy in Relapsed/Refractory Large B-Cell Lymphoma

Kunhwa Kim, Amy Ayers, Sairah Ahmed, Linda Claret, Paolo Strati, Ranjit Nair, Chijioke Nze, Jeremy Ramdial, Janet Torres, Elizabeth J. Shpall, Luis E. Fayad, Loretta Nastoupil, Jason R. Westin, Christopher R. Flowers, Sattva S. Neelapu, Dai Chihara
Journal: Blood
Blood (2024) 144 (Supplement 1): 5121.
https://doi.org/10.1182/blood-2024-211023
Published: 2024
Journal Articles

Real World Data of Novel Talicabtagene Autoleucel (humanized CD19 CAR-T) from India; Ensuring Equitable Access with Excellent Safety and Efficacy Profile

Hasmukh Jain, Atharva Karulkar, Devanshi Kalra, Smrithi Ravikumar, Shreshtha Shah, Afrin Firfiray, Juber Pendhari, Manivasagam S, Anand Vaibhaw, Ashish Saroha, Ankesh K. Jaiswal, Alok Shetty, Lingaraj Nayak, Bhausaheb Bagal, Neeraj Siddharthan, Esha Kaul, Prashant Mehta, Anshul Gupta, Navin Khattry, Nishant Jindal, Sanket P Shah, Rakesh Kumar Boya, Pavan Kumar Boyella, Preeti Desai, Anisha Navkudkar, Shalini Purwar, Manju Sengar, Nirali N. Shah, Sattva S. Neelapu, Rahul Purwar
Journal: Blood
Blood (2024) 144 (Supplement 1): 3755.
https://doi.org/10.1182/blood-2024-202335
Published: 2024
Journal Articles

Clinical Response after Allogeneic CAR T Cell Therapy Is Linked to Expansion of Identical CD8+ Effector-like T Cell Clones

Andrew P Jallouk, Zhongqi Ge, Vivek Kaimal, Paul B Robbins, Zachary J Roberts, Sattva S. Neelapu, Pavan Bachireddy
Journal: Blood
Blood (2024) 144 (Supplement 1): 4783.
https://doi.org/10.1182/blood-2024-197969
Published: 2024
Journal Articles

Developing a Fit-for-Purpose Composite Symptom Score for Representing Symptom Burden for Managing CRS and Icans after CAR T-Cell Therapy

Xin Shelley Wang, Samer A. Srour, Sattva S. Neelapu, Shu-En Shen, Laila Noor, Sairah Ahmed, Elizabeth J. Shpall
Journal: Blood
Blood (2024) 144 (Supplement 1): 2282.
https://doi.org/10.1182/blood-2024-210494
Published: 2024
Journal Articles

An Integrated Spatial, Codex, and Genomic Analysis Predicts Responsiveness and Survival in the Phase II Combination of Pembrolizumab and Romidepsin in PTCL

Ranjit Nair, Daniela E. Duenas, Jingjing Liu, Rishab Prakash, Chen Zhou, Ayse A Koksoy, Jie Xu, Salome A McAllen, Luis Malpica, Raja Luthra, Francisco Vega, Roberto N. Miranda, Jianhua Zhang, L. Jeffrey Medeiros, Cara L Haymaker, Christopher R. Flowers, Sattva S. Neelapu, Swami P. Iyer
Journal: Blood
Blood (2024) 144 (Supplement 1): 455.
https://doi.org/10.1182/blood-2024-211900
Published: 2024
Journal Articles

Use of Molecular Immune Signatures for Frontline Treatment Selection in Patients with Advanced Stage Follicular Lymphoma

Tony Z. Zhuang, Lei Feng, Dai Chihara, Chijioke Nze, Amy A. Ayers, Mansoor Noorani, James D. Ayres, Daniela E. Duenas, Kumudha Balakrishnan, Ekaterina Nesterenko, Mark Meerson, Ksenia Zornikova, Krystle Nomie, Nikita Kotlov, Nathan Fowler, Maria Alma Rodriguez, Sattva S. Neelapu, Christopher R. Flowers, Paolo Strati
Journal: Blood
Blood (2024) 144 (Supplement 1): 2982.
https://doi.org/10.1182/blood-2024-202654
Published: 2024
Journal Articles

5-Year Follow-up Analysis from ZUMA-5: A Phase 2 Trial of Axicabtagene Ciloleucel (Axi-Cel) in Patients with Relapsed/Refractory Indolent Non-Hodgkin Lymphoma

Sattva S. Neelapu, Julio C. Chavez, Alison R. Sehgal, Narendranath Epperla, Matthew Ulrickson, Emmanuel Bachy, Pashna N. Munshi, Carla Casulo, David G. Maloney, Sven de Vos, Ran Reshef, Lori A. Leslie, Olalekan O. Oluwole, Ibrahim Yakoub-Agha, Rashmi Khanal, Joseph D. Rosenblatt, Jacob Wulff, Rhine Shen, Wangshu Zhang, Soumya Poddar, Harry Miao, Olga Nikolajeva, Caron A. Jacobson
Journal: Blood
Blood (2024) 144 (Supplement 1): 864.
https://doi.org/10.1182/blood-2024-194627
Published: 2024
Journal Articles

Retreatment with R-CHOP-like Therapy Is Active with Durable Responses in Patients with Late Relapse of Diffuse Large B-Cell Lymphoma

Eduardo Edelman Saul, Bryan Valcarcel, Amy A. Ayers, Mansoor Noorani, Dai Chihara, Fateeha Furqan, Sairah Ahmed, Swaminathan P Iyer, Sattva S. Neelapu, Luis E. Fayad, F. B. Hagemeister, Chijioke Nze, Preetesh Jain, Michael Wang, Paolo Strati, Ayushi Chauhan, Francisco Vega, Christopher R. Flowers, Jason R. Westin
Journal: Blood
Blood (2024) 144 (Supplement 1): 4454.
https://doi.org/10.1182/blood-2024-211247
Published: 2024
Journal Articles

T-Cell Lymphoma Associated Hemophagocytic Lymphohistiocytosis Has Worse Survival When Compared to T-Cell Lymphoma: A Retrospective Analysis from a Single Tertiary Center

Amrit S. Gonugunta, Rishab Prakash, Ranjit Nair, Ajlan Al Zaki, Sairah Ahmed, Chijioke Nze, Dai Chihara, Frederick Hagemeister, Hun Ju Lee, Jason R. Westin, Krina K. Patel, Luis E. Fayad, Luis Malpica, Maria Alma Rodriguez, Michael Wang, Preetesh Jain, Paolo Strati, Sattva S. Neelapu, Christopher R. Flowers, Swaminathan P Iyer
Journal: Blood
Blood (2024) 144 (Supplement 1): 6420.
https://doi.org/10.1182/blood-2024-211482
Published: 2024
Journal Articles

Comprehensive Characteristics and Outcomes of Myeloid Neoplasms Following Chimeric Antigen Receptor T-Cell Therapy for Other Hematologic Malignancies

Danielle Hammond, Koji Sasaki, Koichi Takahashi, Elizabeth J. Shpall, Uday Popat, Betul Oran, Gheath Al-Atrash, Krina K. Patel, Jason R. Westin, Sattva S. Neelapu, Yesid Alvarado-Valero, Kelly S. Chien, Naval Daver, Guillermo Montalban-Bravo, Abhishek Maiti, Musa Yilmaz, Elias Jabbour, Naveen Pemmaraju, Mahesh Swaminathan, Jo Ishizawa, Nitin Jain, Alessandra Ferrajoli, Farhad Ravandi, Steven M. Kornblau, Gautam Borthakur, Guillermo Garcia-Manero, Hagop M. Kantarjian, Patrick K. Reville, Hussein A. Abbas
Journal: Blood
Blood (2024) 144 (Supplement 1): 1837.
https://doi.org/10.1182/blood-2024-206801
Published: 2024