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Eiko Hayase
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Journal Articles

Antibiotic-induced loss of gut microbiome metabolic output correlates with clinical responses to CAR T-cell therapy

Rishika Prasad, Abdur Rehman, Lubna Rehman, Faezeh Darbaniyan, Viktoria Blumenberg, Maria-Luisa Schubert, Uria Mor, Eli Zamir, Sabine Schmidt, Tomo Hayase, Chang Chia-Chi, Lauren Kelley McDaniel, Ivonne Flores, Paolo Strati, Ranjit Nair, Dai Chihara, Luis E. Fayad, Sairah Ahmed, Swaminathan P. Iyer, Michael L Wang, Preetesh Jain, Loretta J. Nastoupil, Jason R Westin, Reetakshi Arora, Joel Gordon Turner, Fareed Khawaja, Ranran Wu, Jennifer B Dennison, Meghan Menges, Melanie Hidalgo-Vargas, Kayla M. Reid, Marco L. Davila, Peter Dreger, Felix Korell, Anita Schmitt, Mark R Tanner, Richard E. Champlin, Christopher R. Flowers, Elizabeth J Shpall, Samir Hanash, Sattva S. Neelapu, Michael Schmitt, Marion Subklewe, Johannes Fahrmann, Christoph Stein-Thoeringer, Eran Elinav, Michael D Jain, Eiko Hayase, Robert R Jenq, Neeraj Y Saini
Journal: Blood
Blood blood.2024025366.
https://doi.org/10.1182/blood.2024025366
Published: 2024
Includes: Supplemental data
Journal Articles

GVHD targets organoid-forming bile duct stem cells in a TGF-β–dependent manner

Yuta Hasegawa, Daigo Hashimoto, Zixuan Zhang, Toru Miyajima, Yumika Saito, Wenyu Li, Ryo Kikuchi, Hajime Senjo, Tomoko Sekiguchi, Takahiro Tateno, Xuanzhong Chen, Emi Yokoyama, Shuichiro Takahashi, Hiroyuki Ohigashi, Takahide Ara, Eiko Hayase, Isao Yokota, Takanori Teshima
Journal: Blood
Blood (2024) 144 (8): 904–913.
https://doi.org/10.1182/blood.2023023060
Published: 2024
Includes: Supplemental data
Journal Articles

Engineering T cells to suppress acute GVHD and leukemia relapse after allogeneic hematopoietic stem cell transplantation

Feiyan Mo, Norihiro Watanabe, Kayleigh I. Omdahl, Phillip M. Burkhardt, Xiaoyun Ding, Eiko Hayase, Angela Panoskaltsis-Mortari, Robert R. Jenq, Helen E. Heslop, Leslie S. Kean, Malcolm K. Brenner, Victor Tkachev, Maksim Mamonkin
Journal: Blood
Blood (2023) 141 (10): 1194–1208.
https://doi.org/10.1182/blood.2022016052
Published: 2023
Includes: Supplemental data
Journal Articles

Gvhd Targets Organoid-Forming Biliary Epithelial Stem Cells Via a TGF-β-Dependent Manner

Yuta Hasegawa, Daigo Hashimoto, Ryo Kikuchi, Zixuan Zhang, Hajime Senjo, Tomoko Sekiguchi, Eiko Hayase, Takahiro Tateno, Emi Yokoyama, Shuichiro Takahashi, Xuanzhong Chen, Kazuki Yoneda, Hiroyuki Ohigashi, Takahide Ara, Takanori Teshima
Journal: Blood
Blood (2021) 138 (Supplement 1): 90.
https://doi.org/10.1182/blood-2021-149061
Published: 2021
Journal Articles

Carbapenem Antibiotics Promote Mucus Degradation By Bacteroides and Aggravate Graft-Versus-Host Disease

Eiko Hayase, Tomo Hayase, Chia-Chi Chang, Takahiko Miyama, Jennifer L. Karmouch, Wen-Bin Tsai, Mohamed A. Jamal, Robert R. Jenq
Journal: Blood
Blood (2021) 138 (Supplement 1): 85.
https://doi.org/10.1182/blood-2021-149848
Published: 2021
Journal Articles

Too much TMAO and GVHD

Eiko Hayase, Robert R. Jenq
Journal: Blood
Blood (2020) 136 (4): 383–385.
https://doi.org/10.1182/blood.2020006104
Published: 2020
Journal Articles

Intestinal Goblet Cells Play a Protective Role Against GVHD Via a Lypd8-Dependent Manner after Allogeneic Hematopoietic Stem Cell Transplantation

Takahide Ara, MD, Daigo Hashimoto, MD, PhD, Eiko Hayase, MD, Noizat Clara, MD, Ryu Okumura, MD, PhD, Kiyoshi Takeda, MD, PhD, Takanori Teshima
Journal: Blood
Blood (2018) 132 (Supplement 1): 64.
https://doi.org/10.1182/blood-2018-99-115510
Published: 2018
Journal Articles

Ruxolitinib protects skin stem cells and maintains skin homeostasis in murine graft-versus-host disease

Shuichiro Takahashi, Daigo Hashimoto, Eiko Hayase, Reiki Ogasawara, Hiroyuki Ohigashi, Takahide Ara, Emi Yokoyama, Ko Ebata, Satomi Matsuoka, Geoffrey R. Hill, Junichi Sugita, Masahiro Onozawa, Takanori Teshima
Journal: Blood
Blood (2018) 131 (18): 2074–2085.
https://doi.org/10.1182/blood-2017-06-792614
Published: 2018
Includes: Supplemental data
Journal Articles

Vitamin A–coupled liposomes containing siRNA against HSP47 ameliorate skin fibrosis in chronic graft-versus-host disease

Tomohiro Yamakawa, Hiroyuki Ohigashi, Daigo Hashimoto, Eiko Hayase, Shuichiro Takahashi, Miyono Miyazaki, Kenjiro Minomi, Masahiro Onozawa, Yoshiro Niitsu, Takanori Teshima
Journal: Blood
Blood (2018) 131 (13): 1476–1485.
https://doi.org/10.1182/blood-2017-04-779934
Published: 2018
Includes: Supplemental data
Journal Articles

Intestinal Microbiota Play a Critical Role in Neutrophil Engraftment Posttransplant and Recovery after Chemotherapy By Stimulating T Cell Production of IL-17A

KO Ebata, MD, Daigo Hashimoto, MD PhD, Shuichiro Takahashi, MD, Eiko Hayase, MD, Reiki Ogasawara, MD, Takanori Teshima, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3166.
https://doi.org/10.1182/blood.V130.Suppl_1.3166.3166
Published: 2017
Journal Articles

Gastric Stem Cells Are Targeted in Upper Gastrointestinal GVHD

Eiko Hayase, MD, Daigo Hashimoto, MD, Shuichiro Takahashi, MD, Hiroyuki Ohigashi, MD, Takahiro Tateno, MD, Takahide Ara, MD, Emi Yokoyama, MD, Takanori Teshima, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3173.
https://doi.org/10.1182/blood.V130.Suppl_1.3173.3173
Published: 2017
Journal Articles

Feasibility and Kinetics of CD34+ Hematopoietic Cells Mobilization By Low-Dose Pegfilgrastim in Lymphoma Patients

Hideki Goto, MDPhD, Daisuke Hidaka, MD, Satoshi Yamamoto, MD PhD, Koji Hayasaka, Rie Michimata, Ikuko Kagawa, Kana Sunagoya, Hiroaki Iijima, Eiko Hayase, MD, Souichi Shiratori, MD PhD, Kohei Okada, MD PhD, Junichi Sugita, MD PhD, Masahiro Onozawa, MD PhD, Daigo Hashimoto, MD PhD, Kaoru Kahata, MD PhD, Katsuya Fujimoto, MD PhD, Tomoyuki Endo, MD PhD, Chikara Shimizu, MD PhD, Takanori Teshima, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4478.
https://doi.org/10.1182/blood.V130.Suppl_1.4478.4478
Published: 2017
Journal Articles

Vitamin A-Coupled Liposomes Carrying siRNA Against HSP47 Ameliorate Skin Fibrosis in Chronic Graft-Versus-Host Disease

Tomohiro Yamakawa, MD, Daigo Hashimoto, MD PhD, Eiko Hayase, MD, Shuichiro Takahashi, MD, Takanori Teshima, MD PhD
Journal: Blood
Blood (2016) 128 (22): 4536.
https://doi.org/10.1182/blood.V128.22.4536.4536
Published: 2016
Journal Articles

R-spondin1 Promotes Paneth Cell Growth, Maintains Intestinal Microbial Ecology, and Ameliorates GvHD

Eiko Hayase, MD, Daigo Hashimoto, MD PhD, Kiminori Nakamura, PhD, Yoshitoshi Ogura, PhD, Tetsuya Hayashi, MD PhD, Ken Kurokawa, PhD, Tokiyoshi Ayabe, MD PhD, Takanori Teshima, MD PhD
Journal: Blood
Blood (2015) 126 (23): 230.
https://doi.org/10.1182/blood.V126.23.230.230
Published: 2015
Journal Articles

α-Mannan induces Th17-mediated pulmonary graft-versus-host disease in mice

Hidetaka Uryu, Daigo Hashimoto, Koji Kato, Eiko Hayase, Satomi Matsuoka, Reiki Ogasawara, Shuichiro Takahashi, Yoshinobu Maeda, Hiromi Iwasaki, Toshihiro Miyamoto, Shinobu Saijo, Yoichiro Iwakura, Geoffrey R. Hill, Koichi Akashi, Takanori Teshima
Journal: Blood
Blood (2015) 125 (19): 3014–3023.
https://doi.org/10.1182/blood-2014-12-615781
Published: 2015
Includes: Supplemental data