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Journal Articles

Vitamin A–coupled liposomes containing siRNA against HSP47 ameliorate skin fibrosis in chronic graft-versus-host disease

Tomohiro Yamakawa, Hiroyuki Ohigashi, Daigo Hashimoto, Eiko Hayase, Shuichiro Takahashi, Miyono Miyazaki, Kenjiro Minomi, Masahiro Onozawa, Yoshiro Niitsu, Takanori Teshima

Blood (2018) 131 (13): 1476–1485.

https://doi.org/10.1182/blood-2017-04-779934

Published: 2018

Includes: Supplemental data

Journal Articles

Efficacy and Safety of Micafungin as An Empirical Antifungal Therapy for Suspected Fungal Infection in Patients with Hematological Disorders.

Minoru Yoshida, Kazuo Tamura, Masahiro Imamura, MD, Yoshiro Niitsu, Takeshi Sasaki, Akio Urabe, Kazuma Ohyashiki, Tomoki Naoe, Akihisa Kanamaru, Mitsune Tanimoto, Tohru Masaoka

Blood (2008) 112 (11): 1939.

https://doi.org/10.1182/blood.V112.11.1939.1939

Published: 2008

Journal Articles

Adenoviral Vector-Mediated Transfer of the Indian Hedgehog Gene Modulates Lymphomyelopoiesis In Vivo .

Masayoshi Kobune, MD, PhD, Yutaka Kawano, MD, PhD, Katsunori Sasaki, MD, PhD, Rishu Takimoto, MD, PhD, Junji Kato, MD, PhD, Hirofumi Hamada, MD, PhD, Yoshiro Niitsu, MD, PhD

Blood (2007) 110 (11): 2205.

https://doi.org/10.1182/blood.V110.11.2205.2205

Published: 2007

Journal Articles

Wnt3 / RhoA / ROCK Signaling Pathway Is Involved in VLA6-Dependent Adhesion-Mediated Drug Resistance of Multiple Myeloma.

Masayoshi Kobune, MD, PhD, Yutaka Kawano, MD, PhD, Rishu Takimoto, MD, PhD, Takuya Matsunaga, MD, PhD, Junji Kato, MD, PhD, Hirofumi Hamada, MD, PhD, Yoshiro Niitsu, MD, PhD

Blood (2007) 110 (11): 2518.

https://doi.org/10.1182/blood.V110.11.2518.2518

Published: 2007

Journal Articles

Treatment of Idiopathic Myelofibrosis Employing siRNA for Heat Shock Protein 47 (siRNA/HSP47) Encapsulated in Liposomes.

Junichi Watanabe, MD, Takuya Matsunaga, MD, PhD, Kazuyuki Murase, MD, PhD, Yasushi Sato, MD, PhD, Taiko Nagaya, Hirotoshi Ishiwatari, MD, Sho Takahashi, MD, PhD, Koichi Takada, MD, PhD, Masayoshi Kobune, MD, PhD, Kazuya Shimoda, MD, PhD, Mine Harada, MD, PhD, Yoshiro Niitsu, MD, PhD

Blood (2007) 110 (11): 4646.

https://doi.org/10.1182/blood.V110.11.4646.4646

Published: 2007

Journal Articles

Combination Therapy of Anti-Cancer Drug with FNIII14 Peptide of Fibronectin Effectively Overcome Cell Adhesion Mediated-Drug Resistance of Acute Myelogenous Leukemia.

Takuya Matsunaga, MD, PhD, Fumio Fukai, PhD, Maki Tanaka, MD, Masayoshi Kobune, MD, Hiroki Chiba, MD, Yoshiro Niitsu, MD

Blood (2006) 108 (11): 527.

https://doi.org/10.1182/blood.V108.11.527.527

Published: 2006

Journal Articles

TGFβ Activates p53 Via PP2A in Hematopoietic Cells.

Rishu Takimoto, MD, PhD, Junji Kato, MD, PhD, Koichi Takada, MD, PhD, Daisuke Takahari, MD, Yoshiro Niitsu

Blood (2006) 108 (11): 4335.

https://doi.org/10.1182/blood.V108.11.4335.4335

Published: 2006

Journal Articles

Wnt3 Augments Adhesion Mediated Drug Resistance of Myeloma Cells Via Wnt/RhoA Pathway.

Hiroki Chiba, MD, Masayoshi Kobune, MD, PhD, Kazunori Kato, PhD, Kiminori Nakamura, PhD, Yutaka Kawano, MD, PhD, Rishu Takimoto, MD, PhD, Takuya Matsunaga, MD, PhD, Junji Kato, MD, PhD, Yoshiro Niitsu, MD, PhD, Hirofumi Hamada, MD, PhD

Blood (2005) 106 (11): 5075.

https://doi.org/10.1182/blood.V106.11.5075.5075

Published: 2005

Journal Articles

Late Onset Neutropenia and Decreased Immunoglobulin Concentration after Rituximab Combined Autotransplantation for B Cell Lymphoma.

Yasuo Hirayama, Kyuhei Kohda, Yasuji Hirata, Hiroyuki Kuroda, Takuya Matsunaga, Yuichi Konuma, Makoto Yoshida, Toshiro Sakai, Yoshiro Niitsu

Blood (2005) 106 (11): 5347.

https://doi.org/10.1182/blood.V106.11.5347.5347

Published: 2005

Journal Articles

Ex Vivo Large Scale Generation of Human Platelets from Cord Blood CD34+ Cells.

Takuya Matsunaga, MD, PhD, Ikuta Tanaka, MD, PhD, Masayoshi Kobune, MD, PhD, Yutaka Kawano, MD, PhD, Maki Tanaka, MD, PhD, Takehide Akiyama, MD, Kageaki Kuribayashi, MD, PhD, Takafumi Ninomiya, PhD, Hirofumi Hamada, MD, PhD, Yoshiro Niitsu, MD, PhD

Blood (2005) 106 (11): 1892.

https://doi.org/10.1182/blood.V106.11.1892.1892

Published: 2005

Journal Articles

Human mesenchymal stem cells xenografted directly to rat liver are differentiated into human hepatocytes without fusion

Yasushi Sato, Hironobu Araki, Junji Kato, Kiminori Nakamura, Yutaka Kawano, Masayoshi Kobune, Tsutomu Sato, Koji Miyanishi, Tetsuji Takayama, Minoru Takahashi, Rishu Takimoto, Satoshi Iyama, Takuya Matsunaga, Seiji Ohtani, Akihiro Matsuura, Hirofumi Hamada, Yoshiro Niitsu

Blood (2005) 106 (2): 756–763.

https://doi.org/10.1182/blood-2005-02-0572

Published: 2005

Journal Articles

Combination Therapy of Humanized Chimeric-Anti-Human VLA4 Monoclonal Antibodies and Anti-Cancer Drugs for AML.

Takuya Matsunaga, MD, Kazunori Kato, PhD, Maki Tanaka, MD, Yukari Masuta, PhD, Kageaki Kuribayashi, MD, Naofumi Takemoto, MD, Ikuta Tanaka, MD, Akihito Fujimi, MD, Takehide Akiyama, MD, Hirofumi Hamada, MD, Yoshiro Niitsu, MD

Blood (2004) 104 (11): 4518.

https://doi.org/10.1182/blood.V104.11.4518.4518

Published: 2004

Journal Articles

Ex Vivo Production of Transfusable Red Blood Cells at Large Scale from Cord Blood CD34+ Cells Using a Coculture System with Human Telomerase Catalytic Subunit (hTERT)-Transfected Human Stromal Cells at Early Phase and with Acitivated Macrophage from Cord Blood CD34+ Cells at Late Phase.

Akihito Fujimi, MD, Takuya Matsunaga, MD, Masayoshi Kobune, MD, Yutaka Kawano, MD, Ikuta Tanaka, MD, Naofumi Takemoto, MD, Takehide Akiyama, MD, Hirofumi Hamada, MD, Yoshiro Niitsu, MD

Blood (2004) 104 (11): 2701.

https://doi.org/10.1182/blood.V104.11.2701.2701

Published: 2004

Journal Articles

Indian Hedgehog Stimulates Proliferation of Short-Term NOD/SCID-ß2m null Repopulating Cells on Coculture with Human Stromal Cells.

Masayoshi Kobune, MD, PhD, Yutaka Kawano, MD, PhD, Junji Kato, MD, PhD, Yoshinori Ito, MD, Hiroki Chiba, MD, Kageaki Kuribayashi, MD, PhD, Rishu Takimoto, MD, PhD, Takuya Matsunaga, MD, PhD, Hirofumi Hamada, MD, PhD, Yoshiro Niitsu, MD, PhD

Blood (2004) 104 (11): 1300.

https://doi.org/10.1182/blood.V104.11.1300.1300

Published: 2004

Journal Articles

Impaired Expression of the DNA Repair Factor DDB2 in Human Myeloid Leukemias.

Rishu Takimoto, MD/PhD, Junji Kato, MD/PhD, Koichi Takada, MD/PhD, Takuya Matsunaga, MD/PhD, Yoshiro Niitsu, MD/PhD

Blood (2004) 104 (11): 2046.

https://doi.org/10.1182/blood.V104.11.2046.2046

Published: 2004

Journal Articles

A Novel p53-PP2A Signaling Pathway Is Responsible for Regulation of Hematopoiesis Induced by TGFß.

Rishu Takimoto, MD/PhD, Junji Kato, MD/PhD, Koichi Takada, MD/PhD, Daisuke Takahari, MD, Yoshiro Niitsu, MD/PhD

Blood (2004) 104 (11): 4327.

https://doi.org/10.1182/blood.V104.11.4327.4327

Published: 2004

Journal Articles

Indian hedgehog gene transfer augments hematopoietic support of human stromal cells including NOD/SCID– ß 2 m –/– repopulating cells.

Masayoshi Kobune, Yoshinori Ito, Yutaka Kawano, Katsunori Sasaki, Hiroaki Uchida, Kiminori Nakamura, Hironari Dehari, Hiroki Chiba, Rishu Takimoto, Takuya Matsunaga, Takeshi Terui, Junji Kato, Yoshiro Niitsu, Hirofumi Hamada

Blood (2004) 104 (4): 1002–1009.

https://doi.org/10.1182/blood-2003-09-3347

Published: 2004

Journal Articles

Ex vivo expansion of human umbilical cord hematopoietic progenitor cells using a coculture system with human telomerase catalytic subunit (hTERT) –transfected human stromal cells

Yutaka Kawano, Masayoshi Kobune, Miki Yamaguchi, Kiminori Nakamura, Yoshinori Ito, Katsunori Sasaki, Sho Takahashi, Takafumi Nakamura, Hiroki Chiba, Tsutomu Sato, Takuya Matsunaga, Hiroshi Azuma, Kenji Ikebuchi, Hisami Ikeda, Junji Kato, Yoshiro Niitsu, Hirofumi Hamada

Blood (2003) 101 (2): 532–540.

https://doi.org/10.1182/blood-2002-04-1268

Published: 2003

Journal Articles

Prevention of lethal acute graft-versus-host disease in mice by oral administration of T helper 1 inhibitor, TAK-603

Yue Lu, Sumio Sakamaki, Hiroyuki Kuroda, Toshiro Kusakabe, Yuichi Konuma, Takehide Akiyama, Akihito Fujimi, Naofumi Takemoto, Kyokusen Nishiie, Takuya Matsunaga, Yasuo Hirayama, Junji Kato, Shinichiro Kon, Katsuhisa Kogawa, Yoshiro Niitsu

Blood (2001) 97 (4): 1123–1130.

https://doi.org/10.1182/blood.V97.4.1123

Published: 2001

Journal Articles

Transforming Growth Factor-β1 (TGF-β1) Induces Thrombopoietin From Bone Marrow Stromal Cells, Which Stimulates the Expression of TGF-β Receptor on Megakaryocytes and, in Turn, Renders Them Susceptible to Suppression by TGF-β Itself With High Specificity

Sumio Sakamaki, Yasuo Hirayama, Takuya Matsunaga, Hiroyuki Kuroda, Toshiro Kusakabe, Takehide Akiyama, Yuichi Konuma, Katsunori Sasaki, Naoki Tsuji, Tetsuro Okamoto, Masayoshi Kobune, Katsuhisa Kogawa, Junji Kato, Rishu Takimoto, Ryuzo Koyama, Yoshiro Niitsu

Blood (1999) 94 (6): 1961–1970.

https://doi.org/10.1182/blood.V94.6.1961

Published: 1999

NARROW

Vitamin A–coupled liposomes containing siRNA against HSP47 ameliorate skin fibrosis in chronic graft-versus-host disease

Efficacy and Safety of Micafungin as An Empirical Antifungal Therapy for Suspected Fungal Infection in Patients with Hematological Disorders.

Adenoviral Vector-Mediated Transfer of the Indian Hedgehog Gene Modulates Lymphomyelopoiesis In Vivo .

Wnt3 / RhoA / ROCK Signaling Pathway Is Involved in VLA6-Dependent Adhesion-Mediated Drug Resistance of Multiple Myeloma.

Treatment of Idiopathic Myelofibrosis Employing siRNA for Heat Shock Protein 47 (siRNA/HSP47) Encapsulated in Liposomes.

Combination Therapy of Anti-Cancer Drug with FNIII14 Peptide of Fibronectin Effectively Overcome Cell Adhesion Mediated-Drug Resistance of Acute Myelogenous Leukemia.

TGFβ Activates p53 Via PP2A in Hematopoietic Cells.

Wnt3 Augments Adhesion Mediated Drug Resistance of Myeloma Cells Via Wnt/RhoA Pathway.

Late Onset Neutropenia and Decreased Immunoglobulin Concentration after Rituximab Combined Autotransplantation for B Cell Lymphoma.

Ex Vivo Large Scale Generation of Human Platelets from Cord Blood CD34+ Cells.

Human mesenchymal stem cells xenografted directly to rat liver are differentiated into human hepatocytes without fusion

Combination Therapy of Humanized Chimeric-Anti-Human VLA4 Monoclonal Antibodies and Anti-Cancer Drugs for AML.

Ex Vivo Production of Transfusable Red Blood Cells at Large Scale from Cord Blood CD34+ Cells Using a Coculture System with Human Telomerase Catalytic Subunit (hTERT)-Transfected Human Stromal Cells at Early Phase and with Acitivated Macrophage from Cord Blood CD34+ Cells at Late Phase.

Indian Hedgehog Stimulates Proliferation of Short-Term NOD/SCID-ß2m null Repopulating Cells on Coculture with Human Stromal Cells.

Impaired Expression of the DNA Repair Factor DDB2 in Human Myeloid Leukemias.

A Novel p53-PP2A Signaling Pathway Is Responsible for Regulation of Hematopoiesis Induced by TGFß.

Indian hedgehog gene transfer augments hematopoietic support of human stromal cells including NOD/SCID– ß 2 m –/– repopulating cells.

Ex vivo expansion of human umbilical cord hematopoietic progenitor cells using a coculture system with human telomerase catalytic subunit (hTERT) –transfected human stromal cells

Prevention of lethal acute graft-versus-host disease in mice by oral administration of T helper 1 inhibitor, TAK-603

Transforming Growth Factor-β1 (TGF-β1) Induces Thrombopoietin From Bone Marrow Stromal Cells, Which Stimulates the Expression of TGF-β Receptor on Megakaryocytes and, in Turn, Renders Them Susceptible to Suppression by TGF-β Itself With High Specificity

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American Society of Hematology

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American Society of Hematology

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