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Journal Articles

α-Mannan induces Th17-mediated pulmonary graft-versus-host disease in mice

Hidetaka Uryu, Daigo Hashimoto, Koji Kato, Eiko Hayase, Satomi Matsuoka, Reiki Ogasawara, Shuichiro Takahashi, Yoshinobu Maeda, Hiromi Iwasaki, Toshihiro Miyamoto, Shinobu Saijo, Yoichiro Iwakura, Geoffrey R. Hill, Koichi Akashi, Takanori Teshima

Blood (2015) 125 (19): 3014–3023.

https://doi.org/10.1182/blood-2014-12-615781

Published: 2015

Includes: Supplemental data

Journal Articles

Regulatory T cells are strong promoters of acute ischemic stroke in mice by inducing dysfunction of the cerebral microvasculature

Blood (2013) 121 (4): 679–691.

https://doi.org/10.1182/blood-2012-04-426734

Published: 2013

Includes: Supplemental data

Journal Articles

Regulatory Role of Host IL-17 Via Control of Host Macrophage Activation Contributes to Less Acute Gvhd

Rie Kuroda, MD, Katsuaki Sato, MD, PhD, Hideaki Maeba, MD, Toshihiro Fujiki, MD, Shintaro Mase, MD, Raita Araki, MD, Kazuhito Naka, PhD, Makoto Naito, MD. PhD, Yoichiro Iwakura, PhD, Akihiro Yachie, MD, PhD, Shoichi Koizumi, MD, PhD, Ryosei Nishimura, MD, PhD

Blood (2012) 120 (21): 4669.

https://doi.org/10.1182/blood.V120.21.4669.4669

Published: 2012

Journal Articles

In vivo imaging visualizes discoid platelet aggregations without endothelium disruption and implicates contribution of inflammatory cytokine and integrin signaling

Blood (2012) 119 (8): e45–e56.

https://doi.org/10.1182/blood-2011-09-381400

Published: 2012

Includes: Multimedia, Supplemental data

Journal Articles

Synthetic retinoid Am80 ameliorates chronic graft-versus-host disease by down-regulating Th1 and Th17

Hisakazu Nishimori, Yoshinobu Maeda, Takanori Teshima, Haruko Sugiyama, Koichiro Kobayashi, Yoshiko Yamasuji, Sachiyo Kadohisa, Hidetaka Uryu, Kengo Takeuchi, Takehiro Tanaka, Tadashi Yoshino, Yoichiro Iwakura, Mitsune Tanimoto

Blood (2012) 119 (1): 285–295.

https://doi.org/10.1182/blood-2011-01-332478

Published: 2012

Includes: Supplemental data

Journal Articles

Both Tissue-Derived and Bone Marrow-Derived Host IL-17 Producing Cells Are Required for Preventing Acute Graft-Versus-Host Disease

Rie Kuroda, MD, Hideaki Maeba, MD, Katsuaki Sato, MD, PhD, Kazuhito Naka, PhD, Shintaro Mase, MD, Raita Araki, MD, Toshihiro Fujiki, MD, Yoichiro Iwakura, PhD, Akihiro Yachie, MD, PhD, Shoichi Koizumi, MD, PhD, Ryosei Nishimura, MD, PhD

Blood (2011) 118 (21): 2970.

https://doi.org/10.1182/blood.V118.21.2970.2970

Published: 2011

Journal Articles

Evidence for the Involvement of CXCR4 Signaling in In Vivo Self-Renewal of Transplanted Hematopoietic Stem Cells

Chen-YI LAI, Makoto Otsu, MD, PhD, Motohito Okabe, Sachie Suzuki, M.D., Satoshi Yamazaki, Masafumi Onodera, M.D., Ph.D., Hideo Ema, M.D., Ph.D., Shigeru Kakuta, Ph.D., Yoichiro Iwakura, PhD, Hiromitsu Nakauchi, MD, PhD

Blood (2011) 118 (21): 1888.

https://doi.org/10.1182/blood.V118.21.1888.1888

Published: 2011

Journal Articles

Notch-Hes1 pathway is required for the development of IL-17–producing γδ T cells

Kensuke Shibata, Hisakata Yamada, Tetsuya Sato, Takashi Dejima, Masataka Nakamura, Tomokatsu Ikawa, Hiromitsu Hara, Sho Yamasaki, Ryoichiro Kageyama, Yoichiro Iwakura, Hiroshi Kawamoto, Hiroyuki Toh, Yasunobu Yoshikai

Blood (2011) 118 (3): 586–593.

https://doi.org/10.1182/blood-2011-02-334995

Published: 2011

Includes: Supplemental data

Journal Articles

Differential pathways regulating innate and adaptive antitumor immune responses by particulate and soluble yeast-derived β-glucans

Chunjian Qi, Yihua Cai, Lacey Gunn, Chuanlin Ding, Bing Li, Goetz Kloecker, Keqing Qian, John Vasilakos, Shinobu Saijo, Yoichiro Iwakura, John R. Yannelli, Jun Yan

Blood (2011) 117 (25): 6825–6836.

https://doi.org/10.1182/blood-2011-02-339812

Published: 2011

Includes: Supplemental data

Journal Articles

Role of Il-17 Varies at Different Periods After Hematopoietic Stem Cell Transplantation: Protection From Acute Graft-Versus-Host Disease and Exacerbation of Chronic Graft-Versus-Host Disease.

Rie Kuroda, MD, Ryosei Nishimura, MD, PhD, Katsuaki Sato, MD, Hideaki Maeba, MD, Kazuhito Naka, PhD, Shintaro Mase, MD, Raita Araki, MD, Yasuhiro Ikawa, MD, PhD, Yoichiro Iwakura, PhD, Shoichi Koizumi, MD, PhD, Akihiro Yachie, MD, PhD

Blood (2010) 116 (21): 3741.

https://doi.org/10.1182/blood.V116.21.3741.3741

Published: 2010

Journal Articles

Stem cell mobilization with G-CSF induces type 17 differentiation and promotes scleroderma

Geoffrey R. Hill, Stuart D. Olver, Rachel D. Kuns, Antiopi Varelias, Neil C. Raffelt, Alistair L. Don, Kate A. Markey, Yana A. Wilson, Mark J. Smyth, Yoichiro Iwakura, Joel Tocker, Andrew D. Clouston, Kelli P. A. MacDonald

Blood (2010) 116 (5): 819–828.

https://doi.org/10.1182/blood-2009-11-256495

Published: 2010

Journal Articles

Reciprocal differentiation and tissue-specific pathogenesis of Th1, Th2, and Th17 cells in graft-versus-host disease

Tangsheng Yi, Ying Chen, Lin Wang, Gong Du, Daniel Huang, Dongchang Zhao, Heather Johnston, James Young, Ivan Todorov, Dale T. Umetsu, Lieping Chen, Yoichiro Iwakura, Fouad Kandeel, Stephen Forman, Defu Zeng

Blood (2009) 114 (14): 3101–3112.

https://doi.org/10.1182/blood-2009-05-219402

Published: 2009

Includes: Supplemental data

Journal Articles

IL-17 contributes to CD4-mediated graft-versus-host disease

Lucy W. Kappel, Gabrielle L. Goldberg, Christopher G. King, David Y. Suh, Odette M. Smith, Cassandra Ligh, Amanda M. Holland, Jeremy Grubin, Nicholas M. Mark, Chen Liu, Yoichiro Iwakura, Glenn Heller, Marcel R. M. van den Brink

Blood (2009) 113 (4): 945–952.

https://doi.org/10.1182/blood-2008-08-172155

Published: 2009

Journal Articles

Treg Depletion with Interleukin-2-Diphteriatoxin (IL-2DT) Is Sufficient to Induce Tumor Clearance in Acute Myeloid Leukemia (AML)

Christoph Bucher, MD, Johanna Zhou, PhD, Heidi Mondale, PhD, Meghan Johnson, Luna Liu, Christine Vogtenhuber, PhD, Chris Lees, Yoichiro Iwakura, PhD, Daniel A Vallera, PhD, Brenda Weigel, MD, MSc, Bruce R. Blazar, MD

Blood (2008) 112 (11): 2954.

https://doi.org/10.1182/blood.V112.11.2954.2954

Published: 2008

Journal Articles

Donor Bone Marrow Derived IL-17 Expressing Cells Exacerbate Chronic Graft-Versus-Host Disease in a Murine Bone Marrow Transplantation.

Rie Kuroda, MD, Ryosei Nishimura, MD, PhD, Katsuaki Sato, MD, PhD, Hideaki Maeba, MD, Kazuhito Naka, PhD, Yo Niida, MD, PhD, Raita Araki, MD, Yoichiro Iwakura, PhD, Shoichi Koizumi, MD, PhD, Akihiro Yachie, MD, PhD

Blood (2008) 112 (11): 2345.

https://doi.org/10.1182/blood.V112.11.2345.2345

Published: 2008

Journal Articles

Signaling of vascular endothelial growth factor receptor-1 tyrosine kinase promotes rheumatoid arthritis through activation of monocytes/macrophages

Masato Murakami, Shinobu Iwai, Sachie Hiratsuka, Mai Yamauchi, Kazuhide Nakamura, Yoichiro Iwakura, Masabumi Shibuya

Blood (2006) 108 (6): 1849–1856.

https://doi.org/10.1182/blood-2006-04-016030

Published: 2006

Includes: Supplemental data

Journal Articles

VEGFR-1 (Flt-1) Tyrosine Kinase Signaling Enhances Hematopoiesis, Proliferation/Differentiation and Immunity of Monocyte/Macrophage from Bone Marrow Hematopoietic Stem Cells, and Promotes Rheumatoid Arthritis.

Masato Murakami, PhD, Shinobu Iwai, PhD, Sachie Hirasuka, PhD, Yoichiro Iwakura, PhD, Yoshiro Maru, PhD, Masabumi Shibuya, PhD

Blood (2004) 104 (11): 778.

https://doi.org/10.1182/blood.V104.11.778.778

Published: 2004

Journal Articles

Impaired selectin-ligand biosynthesis and reduced inflammatory responses in β-1,4-galactosyltransferase-I–deficient mice

Masahide Asano, Susumu Nakae, Norihiro Kotani, Naoki Shirafuji, Aya Nambu, Noriyoshi Hashimoto, Hiroto Kawashima, Mayumi Hirose, Masayuki Miyasaka, Seiichi Takasaki, Yoichiro Iwakura

Blood (2003) 102 (5): 1678–1685.

https://doi.org/10.1182/blood-2003-03-0836

Published: 2003

Journal Articles

Requirement for MD-1 in cell surface expression of RP105/CD180 and B-cell responsiveness to lipopolysaccharide

Yoshinori Nagai, Rintaro Shimazu, Hirotaka Ogata, Sachiko Akashi, Katsuko Sudo, Hidetoshi Yamasaki, Shin-Ichi Hayashi, Yoichiro Iwakura, Masao Kimoto, Kensuke Miyake

Blood (2002) 99 (5): 1699–1705.

https://doi.org/10.1182/blood.V99.5.1699

Published: 2002

NARROW

α-Mannan induces Th17-mediated pulmonary graft-versus-host disease in mice

Regulatory T cells are strong promoters of acute ischemic stroke in mice by inducing dysfunction of the cerebral microvasculature

Regulatory Role of Host IL-17 Via Control of Host Macrophage Activation Contributes to Less Acute Gvhd

In vivo imaging visualizes discoid platelet aggregations without endothelium disruption and implicates contribution of inflammatory cytokine and integrin signaling

Synthetic retinoid Am80 ameliorates chronic graft-versus-host disease by down-regulating Th1 and Th17

Both Tissue-Derived and Bone Marrow-Derived Host IL-17 Producing Cells Are Required for Preventing Acute Graft-Versus-Host Disease

Evidence for the Involvement of CXCR4 Signaling in In Vivo Self-Renewal of Transplanted Hematopoietic Stem Cells

Notch-Hes1 pathway is required for the development of IL-17–producing γδ T cells

Differential pathways regulating innate and adaptive antitumor immune responses by particulate and soluble yeast-derived β-glucans

Role of Il-17 Varies at Different Periods After Hematopoietic Stem Cell Transplantation: Protection From Acute Graft-Versus-Host Disease and Exacerbation of Chronic Graft-Versus-Host Disease.

Stem cell mobilization with G-CSF induces type 17 differentiation and promotes scleroderma

Reciprocal differentiation and tissue-specific pathogenesis of Th1, Th2, and Th17 cells in graft-versus-host disease

IL-17 contributes to CD4-mediated graft-versus-host disease

Treg Depletion with Interleukin-2-Diphteriatoxin (IL-2DT) Is Sufficient to Induce Tumor Clearance in Acute Myeloid Leukemia (AML)

Donor Bone Marrow Derived IL-17 Expressing Cells Exacerbate Chronic Graft-Versus-Host Disease in a Murine Bone Marrow Transplantation.

Signaling of vascular endothelial growth factor receptor-1 tyrosine kinase promotes rheumatoid arthritis through activation of monocytes/macrophages

VEGFR-1 (Flt-1) Tyrosine Kinase Signaling Enhances Hematopoiesis, Proliferation/Differentiation and Immunity of Monocyte/Macrophage from Bone Marrow Hematopoietic Stem Cells, and Promotes Rheumatoid Arthritis.

Impaired selectin-ligand biosynthesis and reduced inflammatory responses in β-1,4-galactosyltransferase-I–deficient mice

Requirement for MD-1 in cell surface expression of RP105/CD180 and B-cell responsiveness to lipopolysaccharide

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American Society of Hematology

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American Society of Hematology

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