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Journal Articles

Cancer immunoediting and immune dysregulation in multiple myeloma

Kyohei Nakamura, Mark J. Smyth, Ludovic Martinet

Blood (2020) 136 (24): 2731–2740.

https://doi.org/10.1182/blood.2020006540

Published: 2020

Journal Articles

The Immune System and Progression from Precursor Condition to Active Myeloma

Mark J. Smyth, PhD FAA

Blood (2020) 136 (Supplement 1): SCI5.

https://doi.org/10.1182/blood-2020-133199

Published: 2020

Journal Articles

Donor T Cells Maintain Myeloma-Immune Equilibrium after Autologous Stem Cell Transplantation and Concurrent Immunotherapy Promotes Cure

Simone A Minnie, David Smith, Kate H Gartlan, PhD, Thomas S Watkins, Kate A Markey, PhD MBBS, Camille Guillerey, PhD, Rachel D Kuns, BSc, Kelly R Locke, Antiopi Varelias, PhD, Ping Zhang, Nicholas Huntington, PhD, Marta Chesi, PhD, John J Miles, PhD, Mark J Smyth, PhD, Slavica Vuckovic, PhD, Geoffrey R Hill, MD PhD

Blood (2018) 132 (Supplement 1): 2031.

https://doi.org/10.1182/blood-2018-99-118058

Published: 2018

Journal Articles

Oncogenic-Drivers Dictate Immune Responses to Control Disease Progression in Acute Myeloid Leukaemia

Rebecca Austin, BSc, Megan Bywater, PhD, Jasmin Straube, PhD, Leanne T Cooper, Madeleine Headlam, PhD, Keyur Dave, PhD, Matthias Braun, PhD, Tobias Bald, PhD, Fernando Guimaraes, PhD, Sebastien Jacquelin, PhD, Matthew Witkowski, PhD, Iannis Aifantis, PhD, Geoffrey R Hill, MD PhD, Mark J Smyth, PhD, Steven W. Lane, MD PhD

Blood (2018) 132 (Supplement 1): 904.

https://doi.org/10.1182/blood-2018-99-112009

Published: 2018

Journal Articles

Myeloma escape after stem cell transplantation is a consequence of T-cell exhaustion and is prevented by TIGIT blockade

Simone A. Minnie, Rachel D. Kuns, Kate H. Gartlan, Ping Zhang, Andrew N. Wilkinson, Luke Samson, Camille Guillerey, Christian Engwerda, Kelli P. A. MacDonald, Mark J. Smyth, Kate A. Markey, Slavica Vuckovic, Geoffrey R. Hill

Blood (2018) 132 (16): 1675–1688.

https://doi.org/10.1182/blood-2018-01-825240

Published: 2018

Includes: Supplemental data

Journal Articles

TIGIT immune checkpoint blockade restores CD8 + T-cell immunity against multiple myeloma

Camille Guillerey, Heidi Harjunpää, Nadège Carrié, Sahar Kassem, Tricia Teo, Kim Miles, Sophie Krumeich, Marianne Weulersse, Marine Cuisinier, Kimberley Stannard, Yuan Yu, Simone A. Minnie, Geoffrey R. Hill, William C. Dougall, Hervé Avet-Loiseau, Michele W. L. Teng, Kyohei Nakamura, Ludovic Martinet, Mark J. Smyth

Blood (2018) 132 (16): 1689–1694.

https://doi.org/10.1182/blood-2018-01-825265

Published: 2018

Journal Articles

In Vivo Expansion of Recipient DC Leads to Deletion of Donor Alloreactive CD8 + T Cells and Is an Alternative to Post-Transplant Cyclophosphamide for the Prevention of Graft-Versus-Host Disease after BMT

Kate A Markey, MBBS, PhD, Rachel D Kuns, BSc, Daniel J Browne, BSc, Kate H Gartlan, PhD, Renee J Robb, PhD, J Paulo Martins, BSc, Andrea S Henden, MBBS, Simone A Minnie, BSc, Melody Cheong, PhD, Motoko Koyama, MD PhD, Mark J Smyth, PhD, Gabrielle T Belz, PhD, Thomas Brocker, PhD, Mariapia Degli-Esposti, PhD, Steven W. Lane, MD PhD, Geoff R Hill, MD

Blood (2017) 130 (Supplement 1): 4443.

https://doi.org/10.1182/blood.V130.Suppl_1.4443.4443

Published: 2017

Journal Articles

GVHD prevents NK-cell–dependent leukemia and virus-specific innate immunity

Mark D. Bunting, Antiopi Varelias, Fernando Souza-Fonseca-Guimaraes, Iona S. Schuster, Katie E. Lineburg, Rachel D. Kuns, Peter Fleming, Kelly R. Locke, Nicholas D. Huntington, Bruce R. Blazar, Steven W. Lane, Siok-Keen Tey, Kelli P. A. MacDonald, Mark J. Smyth, Mariapia A. Degli-Esposti, Geoffrey R. Hill

Blood (2017) 129 (5): 630–642.

https://doi.org/10.1182/blood-2016-08-734020

Published: 2017

Includes: Supplemental data

Journal Articles

Tc17 cells are a proinflammatory, plastic lineage of pathogenic CD8 + T cells that induce GVHD without antileukemic effects

Blood (2015) 126 (13): 1609–1620.

https://doi.org/10.1182/blood-2015-01-622662

Published: 2015

Includes: Supplemental data

Journal Articles

Promoting regulation via the inhibition of DNAM-1 after transplantation

Motoko Koyama, Rachel D. Kuns, Stuart D. Olver, Katie E. Lineburg, Mary Lor, Bianca E. Teal, Neil C. Raffelt, Lucie Leveque, Christopher J. Chan, Renee J. Robb, Kate A. Markey, Kylie A. Alexander, Antiopi Varelias, Andrew D. Clouston, Mark J. Smyth, Kelli P. A. MacDonald, Geoffrey R. Hill

Blood (2013) 121 (17): 3511–3520.

https://doi.org/10.1182/blood-2012-07-444026

Published: 2013

Journal Articles

Promoting Regulation Via the Inhibition of DNAM-1 After Transplantation

Motoko Koyama, MD, PhD, Rachel D Kuns, Stuart D Olver, Katie E Lineburg, Mary Lor, Bianca E Teal, Neil C Raffelt, Lucie Leveque, Christopher J Chan, Renee J Robb, PhD, Kate A Markey, MD, PhD, Kylie A Alexander, PhD, Antiopi Varelias, PhD, Andrew D Clouston, MD, Kelli P A MacDonald, PhD, Mark J Smyth, PhD, Geoffrey R Hill, MD

Blood (2012) 120 (21): 338.

https://doi.org/10.1182/blood.V120.21.338.338

Published: 2012

Journal Articles

NKT cell adjuvant-based tumor vaccine for treatment of myc oncogene-driven mouse B-cell lymphoma

Stephen R. Mattarollo, Alison C. West, Kim Steegh, Helene Duret, Christophe Paget, Ben Martin, Geoffrey M. Matthews, Jake Shortt, Marta Chesi, P. Leif Bergsagel, Michael Bots, Johannes Zuber, Scott W. Lowe, Ricky W. Johnstone, Mark J. Smyth

Blood (2012) 120 (15): 3019–3029.

https://doi.org/10.1182/blood-2012-04-426643

Published: 2012

Includes: Supplemental data

Journal Articles

Response: dexamethasone dose alters expression of NK activating receptors in vivo

Andy Hsu, Hang Quach, Tsin Tai, H. Miles Prince, Simon J. Harrison, Joseph A. Trapani, Mark J. Smyth, Paul J. Neeson, David S. Ritchie

Blood (2011) 118 (24): 6466–6468.

https://doi.org/10.1182/blood-2011-10-382291

Published: 2011

Journal Articles

Autologous Peripheral Blood T Lymphocytes Transduced with An Anti LewisY Chimeric Receptor Gene Persist In Patients with Lewis y Positive Acute Myeloid Leukaemia and Show Changes In Functional Polarization After Adoptive Transfer,

Paul Neeson, PhD, Amit S Khot, MBBS, MD, MRCP, FRCPath, Stefan Peinert, MD, Tsin Y Tai, MSc, Karen Chen, Kellie Tainton, BSc, Dominic Wall, PhD, Dirk Hoenemann, MD, Michael H Kershaw, PhD, Jennifer Westwood, Joe Trapani, PhD, Mark J Smyth, PhD, Phillip Darcy, PhD, Andrew Scott, PhD, Lucy Kravets, BSc, Jill Davison, RN, Michael J. Dickinson, MBBS, FRACP, FRCPA, David Ritchie, MBBS, FRACP, FRCPA, PhD, Miles Prince, MD, FRACP, FRCPA

Blood (2011) 118 (21): 4180.

https://doi.org/10.1182/blood.V118.21.4180.4180

Published: 2011

Journal Articles

A role for Blimp1 in the transcriptional network controlling natural killer cell maturation

Axel Kallies, Sebastian Carotta, Nicholas D. Huntington, Nicholas J. Bernard, David M. Tarlinton, Mark J. Smyth, Stephen L. Nutt

Blood (2011) 117 (6): 1869–1879.

https://doi.org/10.1182/blood-2010-08-303123

Published: 2011

Includes: Supplemental data

Journal Articles

The immunostimulatory effect of lenalidomide on NK-cell function is profoundly inhibited by concurrent dexamethasone therapy

Andy K. Hsu, Hang Quach, Tsin Tai, H. Miles Prince, Simon J. Harrison, Joseph A. Trapani, Mark J. Smyth, Paul Neeson, David S. Ritchie

Blood (2011) 117 (5): 1605–1613.

https://doi.org/10.1182/blood-2010-04-278432

Published: 2011

Includes: Supplemental data

Journal Articles

Stem cell mobilization with G-CSF induces type 17 differentiation and promotes scleroderma

Geoffrey R. Hill, Stuart D. Olver, Rachel D. Kuns, Antiopi Varelias, Neil C. Raffelt, Alistair L. Don, Kate A. Markey, Yana A. Wilson, Mark J. Smyth, Yoichiro Iwakura, Joel Tocker, Andrew D. Clouston, Kelli P. A. MacDonald

Blood (2010) 116 (5): 819–828.

https://doi.org/10.1182/blood-2009-11-256495

Published: 2010

Journal Articles

Does IL-17 suppress tumor growth?

Shin Foong Ngiow, Mark J. Smyth, Michele W. L. Teng

Blood (2010) 115 (12): 2554–2555.

https://doi.org/10.1182/blood-2009-11-254607

Published: 2010

Journal Articles

Type I natural killer T cells suppress tumors caused by p53 loss in mice

Jeremy B. Swann, Adam P. Uldrich, Serani van Dommelen, Janelle Sharkey, William K. Murray, Dale I. Godfrey, Mark J. Smyth

Blood (2009) 113 (25): 6382–6385.

https://doi.org/10.1182/blood-2009-01-198564

Published: 2009

Includes: Supplemental data

Journal Articles

Invariant natural killer T cell–natural killer cell interactions dictate transplantation outcome after α-galactosylceramide administration

Rachel D. Kuns, Edward S. Morris, Kelli P. A. MacDonald, Kate A. Markey, Helen M. Morris, Neil C. Raffelt, Tatjana Banovic, Alistair L. J. Don, Vanessa Rowe, Angela C. Burman, Andrew D. Clouston, Camile Farah, Gurdyal S. Besra, Petr A. Illarionov, Mark J. Smyth, Steven A. Porcelli, Geoffrey R. Hill

Blood (2009) 113 (23): 5999–6010.

https://doi.org/10.1182/blood-2008-10-183335

Published: 2009

NARROW

Cancer immunoediting and immune dysregulation in multiple myeloma

The Immune System and Progression from Precursor Condition to Active Myeloma

Donor T Cells Maintain Myeloma-Immune Equilibrium after Autologous Stem Cell Transplantation and Concurrent Immunotherapy Promotes Cure

Oncogenic-Drivers Dictate Immune Responses to Control Disease Progression in Acute Myeloid Leukaemia

Myeloma escape after stem cell transplantation is a consequence of T-cell exhaustion and is prevented by TIGIT blockade

TIGIT immune checkpoint blockade restores CD8 + T-cell immunity against multiple myeloma

In Vivo Expansion of Recipient DC Leads to Deletion of Donor Alloreactive CD8 + T Cells and Is an Alternative to Post-Transplant Cyclophosphamide for the Prevention of Graft-Versus-Host Disease after BMT

GVHD prevents NK-cell–dependent leukemia and virus-specific innate immunity

Tc17 cells are a proinflammatory, plastic lineage of pathogenic CD8 + T cells that induce GVHD without antileukemic effects

Promoting regulation via the inhibition of DNAM-1 after transplantation

Promoting Regulation Via the Inhibition of DNAM-1 After Transplantation

NKT cell adjuvant-based tumor vaccine for treatment of myc oncogene-driven mouse B-cell lymphoma

Response: dexamethasone dose alters expression of NK activating receptors in vivo

Autologous Peripheral Blood T Lymphocytes Transduced with An Anti LewisY Chimeric Receptor Gene Persist In Patients with Lewis y Positive Acute Myeloid Leukaemia and Show Changes In Functional Polarization After Adoptive Transfer,

A role for Blimp1 in the transcriptional network controlling natural killer cell maturation

The immunostimulatory effect of lenalidomide on NK-cell function is profoundly inhibited by concurrent dexamethasone therapy

Stem cell mobilization with G-CSF induces type 17 differentiation and promotes scleroderma

Does IL-17 suppress tumor growth?

Type I natural killer T cells suppress tumors caused by p53 loss in mice

Invariant natural killer T cell–natural killer cell interactions dictate transplantation outcome after α-galactosylceramide administration

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American Society of Hematology

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ASH Publications

American Society of Hematology

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