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Journal Articles

Nrf2 regulates CD4 + T cell–induced acute graft-versus-host disease in mice

Blood (2018) 132 (26): 2763–2774.

https://doi.org/10.1182/blood-2017-10-812941

Published: 2018

Includes: Supplemental data

Journal Articles

Sex Steroid Blockade Enhances Thymopoiesis By Modulating Notch Signaling

Enrico Velardi, PhD, Jennifer J Tsai, M.D., Amanda M. Holland, PhD, Natalie V Singer, BS, Mallory L West, BS, Odette M Smith, BA, Lauren F. Young, BS, Fabiana M Kreines, BS, Emily R Levy, BS, Richard Boyd, PhD, Marcel R. M. van den Brink, MD, PhD, Jarrod A Dudakov, PhD

Blood (2013) 122 (21): 291.

https://doi.org/10.1182/blood.V122.21.291.291

Published: 2013

Journal Articles

CD19-Targeted Donor T Cells Exert Potent Graft Versus Lymphoma Activity and Attenuated Gvhd

Arnab Ghosh, MD, PhD, Marco L. Davila, MD, PhD, Lauren F. Young, BS, Christopher Kloss, BS, Gertrude Gunset, BS, Odette M. Smith, BA, Mallory L. West, BS, Natalie V. Singer, BS, Amanda M. Holland, BS, Robert R. Jenq, MD, Alan M. Hanash, MD, PhD, Jarrod A. Dudakov, PhD, Enrico Velardi, PhD, Yusuke Shono, MD, PhD, Michel Sadelain, MD, PhD, Marcel R.M. van den Brink, MD, PhD

Blood (2012) 120 (21): 451.

https://doi.org/10.1182/blood.V120.21.451.451

Published: 2012

Journal Articles

Over-Expression of TRAIL on Donor T Cells Enhances GVT and Suppresses Gvhd Via Elimination of Alloreactive T Cells and Host APC

Arnab Ghosh, MD, PhD, Yildirim Dogan, PhD, Amanda M. Holland, BS, Odette M Smith, BA, Lauren F. Young, BS, Mallory L West, BS, Natalie V Singer, BS, Robert R Jenq, MD, Il-Kang Na, MD/PhD, Olaf Penack, MD/PhD, Alan M Hanash, MD, PhD, Martin G. Sauer, MD, Michel Sadelain, MD, PhD, Marcel R.M. van den Brink, MD, PhD

Blood (2011) 118 (21): 817.

https://doi.org/10.1182/blood.V118.21.817.817

Published: 2011

Journal Articles

Innate Lymphoid Cell-Derived IL-22 Mediates Endogenous Thymic Repair Under the Control of IL-23

Jarrod A Dudakov, PhD, Alan M Hanash, MD, PhD, Lauren F. Young, BS, Natalie V Singer, BS, Mallory L West, BS, Robert R Jenq, MD, Odette M Smith, BA, Amanda M Holland, BS, Richard L Boyd, PhD, Marcel R.M. van den Brink, MD, PhD

Blood (2011) 118 (21): 143.

https://doi.org/10.1182/blood.V118.21.143.143

Published: 2011

Journal Articles

Host-Derived IL-22 Limits Graft Versus Host Disease and Protects the Intestinal Stem Cell Niche

Alan M. Hanash, MD, PhD, Jarrod A Dudakov, PhD, Guoqiang Hua, PhD, Lauren F. Young, BS, Maggie O'connor, Robert R Jenq, MD, Amanda M Holland, BS, Odette M Smith, BA, Chen Liu, PhD, Lynette Fouser, PhD, Richard Kolesnick, PhD, Bruce R. Blazar, MD, Marcel Van Den Brink, MD, PhD

Blood (2011) 118 (21): 309.

https://doi.org/10.1182/blood.V118.21.309.309

Published: 2011

Journal Articles

Abrogation of donor T-cell IL-21 signaling leads to tissue-specific modulation of immunity and separation of GVHD from GVL

Alan M. Hanash, Lucy W. Kappel, Nury L. Yim, Rebecca A. Nejat, Gabrielle L. Goldberg, Odette M. Smith, Uttam K. Rao, Lindsay Dykstra, Il-Kang Na, Amanda M. Holland, Jarrod A. Dudakov, Chen Liu, George F. Murphy, Warren J. Leonard, Glenn Heller, Marcel R. M. van den Brink

Blood (2011) 118 (2): 446–455.

https://doi.org/10.1182/blood-2010-07-294785

Published: 2011

Includes: Supplemental data

Journal Articles

Abrogation of Donor T Cell IL-21 Signaling Leads to Tissue-Specific Modulation of Immunity and Separation of Gvhd From GVL

Alan M. Hanash, MD, PhD, Lucy W. Kappel, Nury L. Yim, Rebecca A. Nejat, Gabrielle L. Goldberg, Odette M. Smith, Uttam K. Rao, Lindsay Dykstra, Il-Kang Na, Amanda M. Holland, Chen Liu, George F. Murphy, Warren J Leonard, Glenn Heller, PhD, Marcel R.M. van den Brink, MD, PhD

Blood (2010) 116 (21): 729.

https://doi.org/10.1182/blood.V116.21.729.729

Published: 2010

Journal Articles

Genetic Engineering of Donor T Cells for BMT Immunotherapy: Expression of TRAIL and PLZF Selectively Enhances GVT and Abrogates Gvhd

Arnab Ghosh, MD, PhD, Amanda M. Holland, BS, Yildirim Dogan, PhD, Nury Yim, BS, Uttam K. Rao, BA, Lauren F. Young, BS, Odette M. Smith, BA, Robert Jenq, MD, Il-Kang Na, MD/PhD, Jennifer Tsai, MD, Olaf Penack, MD/PhD, Alan M. Hanash, MD, PhD, Martin G. Sauer, MD, Derek Sant'Angelo, PhD, Michel Sadelain, MD, PhD, Marcel R.M. van den Brink, MD, PhD

Blood (2010) 116 (21): 730.

https://doi.org/10.1182/blood.V116.21.730.730

Published: 2010

Journal Articles

Gvhd, Hematopoietic Dysfunction, and Post-Transplant Immune Deficiency: Loss of Marrow Function Leads to Ineffective Extramedullary Hematopoiesis, However Lymphoid Reconstitution Is Restored by the Synergistic Effects of KGF, Sex Steroid Ablation, and Precursor T Cell Adoptive Therapy.

Jarrod A Dudakov, PhD, Alan M. Hanash, MD, PhD, Uttam K. Rao, Amanda M. Holland, Robert Jenq, MD, Gabrielle L. Goldberg, PhD, Richard Boyd, PhD, Marcel R.M. van den Brink, MD, PhD

Blood (2010) 116 (21): 1468.

https://doi.org/10.1182/blood.V116.21.1468.1468

Published: 2010

Journal Articles

Concurrent visualization of trafficking, expansion, and activation of T lymphocytes and T-cell precursors in vivo

Il-Kang Na, John C. Markley, Jennifer J. Tsai, Nury L. Yim, Bradley J. Beattie, Alexander D. Klose, Amanda M. Holland, Arnab Ghosh, Uttam K. Rao, Matthias T. Stephan, Inna Serganova, Elmer B. Santos, Renier J. Brentjens, Ronald G. Blasberg, Michel Sadelain, Marcel R. M. van den Brink

Blood (2010) 116 (11): e18–e25.

https://doi.org/10.1182/blood-2009-12-259432

Published: 2010

Includes: Supplemental data

Journal Articles

P-Selectin in Recipients of Allogeneic Bone Marrow Transplantation Regulates Experimental Graft-Versus-Host-Disease.

Sydney X Lu, PhD, Maria Lia Palomba, MD, Il-Kang Na, MD, Theis Terwey, Onder Alpdogan, MD, Jhoanne L Bautista, Marsinay O Smith, David Suh, Christopher King, Uttam Rao, Nury Yim, Robert R. Jenq, MD, Johannes L Zakrzewski, MD, Amanda M. Holland, Olaf Penack, MD, Lindsay Dykstra, Kevin Bampoe, Marcel R.M. van den Brink, MD, PhD

Blood (2009) 114 (22): 1335.

https://doi.org/10.1182/blood.V114.22.1335.1335

Published: 2009

Journal Articles

NOD2 Regulates Hematopoietic Cell Function During Graft-Versus-Host Disease.

Olaf Penack, Odette M. Smith, Nury Yim, Uttam Rao, Arnab Ghosh, George F Murphy, Amanda M. Holland, Robert R. Jenq, MD, Sydney X Lu, Il-Kang Na, MD, Marcel R.M. van den Brink, MD, PhD

Blood (2009) 114 (22): 2453.

https://doi.org/10.1182/blood.V114.22.2453.2453

Published: 2009

Journal Articles

TRAIL/ DR5 Interactions Are Important for Thymic Damage After Allogeneic Bone Marrow Transplantation.

Blood (2009) 114 (22): 234.

https://doi.org/10.1182/blood.V114.22.234.234

Published: 2009

Journal Articles

Concurrent Visualization of Trafficking and NFAT Signalling in Primary T Lymphocytes and T Cell Precursors In Vivo.

Il-Kang Na, MD, John Markley, MD, PhD, Jennifer Tsai, MD, Nury L. Yim, Bradley J. Beattie, Alexander D. Klose, PhD, Amanda M. Holland, Arnab Ghosh, MD, PhD, Uttam K. Rao, Matthias Stephan, MD, PhD, Inna Serganova, PhD, Renier J. Brentjens, MD, PhD, Ron R.G. Blasberg, MD, Michel W Sadelain, MD, PhD, Marcel R.M. van den Brink, MD, PhD

Blood (2009) 114 (22): 914.

https://doi.org/10.1182/blood.V114.22.914.914

Published: 2009

Journal Articles

Keratinocyte growth factor enhances DNA plasmid tumor vaccine responses after murine allogeneic bone marrow transplantation

Blood (2009) 113 (7): 1574–1580.

https://doi.org/10.1182/blood-2008-05-155697

Published: 2009

Journal Articles

IL-17 contributes to CD4-mediated graft-versus-host disease

Lucy W. Kappel, Gabrielle L. Goldberg, Christopher G. King, David Y. Suh, Odette M. Smith, Cassandra Ligh, Amanda M. Holland, Jeremy Grubin, Nicholas M. Mark, Chen Liu, Yoichiro Iwakura, Glenn Heller, Marcel R. M. van den Brink

Blood (2009) 113 (4): 945–952.

https://doi.org/10.1182/blood-2008-08-172155

Published: 2009

Journal Articles

The T Cell Cytolytic Molecules Fas Ligand and TRAIL, the Trafficking Molecules CCR9, β7 Integrin and PSGL-1, and the Immune Modulating Molecules OX40, CEACAM1, and CTLA4 Are Required for Thymic Graft-Versus-Host Disease

Blood (2008) 112 (11): 65.

https://doi.org/10.1182/blood.V112.11.65.65

Published: 2008

Journal Articles

Targeted ‘Off-the-Shelf’ Tumor Immunotherapy Using Allogeneic T-Cell Precursors.

Johannes L. Zakrzewski, MD, David Suh, Odette M. Smith, Christopher King, Gabrielle L. Goldberg, PhD, Robert Jenq, MD, Amanda M. Holland, Jeremy Grubin, Sydney X. Lu, Javier Cabrera-Perez, Gabrielle Rizzuto, Derek B. Sant’Angelo, PhD, Marcel R.M. van den Brink, MD, PhD, John C. Markley, Isabelle Riviere, PhD, Michel Sadelain, MD, PhD, Juan Carlos Zuniga-Pflucker, PhD

Blood (2007) 110 (11): 579.

https://doi.org/10.1182/blood.V110.11.579.579

Published: 2007

NARROW

Nrf2 regulates CD4 + T cell–induced acute graft-versus-host disease in mice

Sex Steroid Blockade Enhances Thymopoiesis By Modulating Notch Signaling

CD19-Targeted Donor T Cells Exert Potent Graft Versus Lymphoma Activity and Attenuated Gvhd

Over-Expression of TRAIL on Donor T Cells Enhances GVT and Suppresses Gvhd Via Elimination of Alloreactive T Cells and Host APC

Innate Lymphoid Cell-Derived IL-22 Mediates Endogenous Thymic Repair Under the Control of IL-23

Host-Derived IL-22 Limits Graft Versus Host Disease and Protects the Intestinal Stem Cell Niche

Abrogation of donor T-cell IL-21 signaling leads to tissue-specific modulation of immunity and separation of GVHD from GVL

Abrogation of Donor T Cell IL-21 Signaling Leads to Tissue-Specific Modulation of Immunity and Separation of Gvhd From GVL

Genetic Engineering of Donor T Cells for BMT Immunotherapy: Expression of TRAIL and PLZF Selectively Enhances GVT and Abrogates Gvhd

Gvhd, Hematopoietic Dysfunction, and Post-Transplant Immune Deficiency: Loss of Marrow Function Leads to Ineffective Extramedullary Hematopoiesis, However Lymphoid Reconstitution Is Restored by the Synergistic Effects of KGF, Sex Steroid Ablation, and Precursor T Cell Adoptive Therapy.

Concurrent visualization of trafficking, expansion, and activation of T lymphocytes and T-cell precursors in vivo

P-Selectin in Recipients of Allogeneic Bone Marrow Transplantation Regulates Experimental Graft-Versus-Host-Disease.

NOD2 Regulates Hematopoietic Cell Function During Graft-Versus-Host Disease.

TRAIL/ DR5 Interactions Are Important for Thymic Damage After Allogeneic Bone Marrow Transplantation.

Concurrent Visualization of Trafficking and NFAT Signalling in Primary T Lymphocytes and T Cell Precursors In Vivo.

Keratinocyte growth factor enhances DNA plasmid tumor vaccine responses after murine allogeneic bone marrow transplantation

IL-17 contributes to CD4-mediated graft-versus-host disease

The T Cell Cytolytic Molecules Fas Ligand and TRAIL, the Trafficking Molecules CCR9, β7 Integrin and PSGL-1, and the Immune Modulating Molecules OX40, CEACAM1, and CTLA4 Are Required for Thymic Graft-Versus-Host Disease

Targeted ‘Off-the-Shelf’ Tumor Immunotherapy Using Allogeneic T-Cell Precursors.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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