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Journal Articles

IFNγR Signaling As a Therapeutic Target To Prevent GvHD While Preserving Gvl

Jaebok Choi, PhD, Matthew L Cooper, PhD, Julie Ritchey, Lynne Collins, Julie Prior, David Piwnica-Worms, MD, PhD, John F. Dipersio, MD, PhD

Blood (2013) 122 (21): 4464.

https://doi.org/10.1182/blood.V122.21.4464.4464

Published: 2013

Journal Articles

Interruption of IFNγR Signaling Results in Altered T Cell Trafficking in Vivo and Abrogation of GvHD While Maintaining a Robust Gvl Response

Jaebok Choi, PhD., Edward Dela Ziga, MD, MPH, Julie Ritchey, Lynne Collins, Julie Prior, Matthew Cooper, PhD, David Piwnica-Worms, MD, PhD, John F. DiPersio, MD, PhD

Blood (2012) 120 (21): 455.

https://doi.org/10.1182/blood.V120.21.455.455

Published: 2012

Journal Articles

IFNγR signaling mediates alloreactive T-cell trafficking and GVHD

Jaebok Choi, Edward D. Ziga, Julie Ritchey, Lynne Collins, Julie L. Prior, Matthew L. Cooper, David Piwnica-Worms, John F. DiPersio

Blood (2012) 120 (19): 4093–4103.

https://doi.org/10.1182/blood-2012-01-403196

Published: 2012

Includes: Supplemental data

Journal Articles

Epoxyketone-Based Proteasome Inhibitors Carfilzomib and Orally Bioavailable ONX 0912 Have Anti-Resorptive and Bone-Anabolic Activity in Addition to Anti-Myeloma Effects

Michelle A Hurchla, Antonio Garcia-Gomez, Mary C Hornick, Enrique M Ocio, Aixiao Li, Juan F Blanco, Lynne Collins, Christopher J Kirk, David Piwnica-Worms, Ravi Vij, MD, Michael H Tomasson, Atanasio Pandiella, Jesús F San Miguel, Mercedes Garayoa, Katherine N Weilbaecher

Blood (2011) 118 (21): 2906.

https://doi.org/10.1182/blood.V118.21.2906.2906

Published: 2011

Journal Articles

Interruption of the IFN γR/CXCR3 Axis Results in Altered T Cell Trafficking In Vivo and Abrogation of GvHD While Maintaining a Robust Gvl Response

Jaebok Choi, PhD., Edward Dela Ziga, MD, MPH, Julie Ritchey, Julie Prior, Lynne Collins, Johnny Wei, David Piwnica-Worms, MD, PhD, John F. DiPersio, MD, PhD

Blood (2011) 118 (21): 2971.

https://doi.org/10.1182/blood.V118.21.2971.2971

Published: 2011

Journal Articles

Effect of In Vivo Azacitidine on GvHD and Gvl: Mechanistic Studies

Jaebok Choi, PhD., Julie Ritchey, Jessica Su, Julie Prior, Edward Ziga, David Piwnica-Worms, John F. DiPersio, MD, PhD

Blood (2010) 116 (21): 2537.

https://doi.org/10.1182/blood.V116.21.2537.2537

Published: 2010

Journal Articles

Chemosensitization of acute myeloid leukemia (AML) following mobilization by the CXCR4 antagonist AMD3100

Bruno Nervi, Pablo Ramirez, Michael P. Rettig, Geoffrey L. Uy, Matthew S. Holt, Julie K. Ritchey, Julie L. Prior, David Piwnica-Worms, Gary Bridger, Timothy J. Ley, John F. DiPersio

Blood (2009) 113 (24): 6206–6214.

https://doi.org/10.1182/blood-2008-06-162123

Published: 2009

Includes: Supplemental data

Journal Articles

Revascularization of ischemic limbs after transplantation of human bone marrow cells with high aldehyde dehydrogenase activity

Benjamin J. Capoccia, Debra L. Robson, Krysta D. Levac, Dustin J. Maxwell, Sarah A. Hohm, Marian J. Neelamkavil, Gillian I. Bell, Anargyros Xenocostas, Daniel C. Link, David Piwnica-Worms, Jan A. Nolta, David A. Hess

Blood (2009) 113 (21): 5340–5351.

https://doi.org/10.1182/blood-2008-04-154567

Published: 2009

Includes: Supplemental data

Journal Articles

Imaging spontaneous tumorigenesis: inflammation precedes development of peripheral NK tumors

Dan Rauch, Shimon Gross, John Harding, Stefan Niewiesk, Michael Lairmore, David Piwnica-Worms, Lee Ratner

Blood (2009) 113 (7): 1493–1500.

https://doi.org/10.1182/blood-2008-07-166462

Published: 2009

Journal Articles

Human Cord Blood Progenitors with High Aldehyde Dehydrogenase Activity Improve Vascular Density in a Model of Acute Myocardial Infarction

Claus Sondergaard, Ph.D., David Hess, PhD, Dustin Maxwell, Ph.D., Ivana Rosova, Carla Weinheimer, Ph.D., Attila Kovacs, Ph.D., Michael Creer, MD, David Piwnica-Worms, MD, PhD, Lene Pederson, Ph.D., Jan Nolta, Ph.D.

Blood (2008) 112 (11): 2895.

https://doi.org/10.1182/blood.V112.11.2895.2895

Published: 2008

Journal Articles

IL-12 Stimulates Interferon-Gamma Mediated Inhibition of Tumor-Induced Regulatory T Cell Proliferation and Enhances Tumor Clearance

Xuefang Cao, PhD, Lynne I. Collins, Sheng F. Cai, Joshua C. Mayer, Michael J. Walter, MD, David Piwnica-Worms, MD, PhD, Robert D. Schreiber, PhD, Timothy J. Ley, MD

Blood (2008) 112 (11): 2558.

https://doi.org/10.1182/blood.V112.11.2558.2558

Published: 2008

Journal Articles

Fluorophore Conjugated Iron Oxide Nanoparticle Labeling and Analysis of Engrafting Human Hematopoietic Stem Cells.

Dustin Maxwell, PhD, David Hess, Ph.D., Jesper Bonde, Ph.D., Sarah A. Hohm, Ryan Lahey, Michael Creer, MD, David Piwnica-Worms, MD, Jan A. Nolta, Ph.D.

Blood (2007) 110 (11): 1213.

https://doi.org/10.1182/blood.V110.11.1213.1213

Published: 2007

Journal Articles

Granulocyte colony-stimulating factor enhances bone tumor growth in mice in an osteoclast-dependent manner

Angela C. Hirbe, Özge Uluçkan, Elizabeth A. Morgan, Mark C. Eagleton, Julie L. Prior, David Piwnica-Worms, Kathryn Trinkaus, Anthony Apicelli, Katherine Weilbaecher

Blood (2006) 109 (8): 3424–3431.

https://doi.org/10.1182/blood-2006-09-048686

Published: 2006

Includes: Supplemental data

Journal Articles

In Vivo Bioluminescence Imaging (BLI) and Sequential 18 F]FHBG microPET Imaging Studies of Human T Cell (huT) Trafficking, Expansion and Xenogeneic Graft-Versus-Host-Disease (XGVHD) Following Different Routes of T Cell Administration.

Bruno Nervi, MD, Michael P. Rettig, PhD, Julie K. Ritchey, Hanlin L. Wang, MD,PhD, Gerhard Bauer, Jon Walker, Julie L. Prior, David Piwnica-Worms, MD,PhD, Jan A. Nolta, PhD, John F. DiPersio, MD,PhD

Blood (2006) 108 (11): 5178.

https://doi.org/10.1182/blood.V108.11.5178.5178

Published: 2006

Journal Articles

CXCR4/SDF-1 Is a Key Regulator for Leukemia Migration and Homing to the BM: Impact of AMD3100 on In Vivo Response to Chemotherapy.

Bruno Nervi, MD, Pablo Ramirez, MD, Matthew Holt, Michael P. Rettig, PhD, Julie K. Ritchey, Julie L. Prior, David Piwnica-Worms, MD,PhD, Gary Bridger, PhD, Timothy J. Ley, MD,PhD, John F. DiPersio, MD,PhD

Blood (2006) 108 (11): 569.

https://doi.org/10.1182/blood.V108.11.569.569

Published: 2006

Journal Articles

Granzyme B Is Important for Treg-Mediated Suppression of NK-Dependent Tumor Clearance In Vivo .

Xuefang Cao, PhD, Sheng F. Cai, BS, Todd A. Fehniger, MD/PhD, Jiling Song, BS, David Piwnica-Worms, MD/PhD, Timothy James Ley, MD

Blood (2006) 108 (11): 133.

https://doi.org/10.1182/blood.V108.11.133.133

Published: 2006

Journal Articles

Bioluminescence Imaging of Spontaneous Lymphomas and Contribution of Distinct NFκB Pathways.

Lee Ratner, MD, PhD, Leon Bernal-Mizrachi, MD, Daniel Rauch, PhD, John Harding, BA, Shimon Gross, PhD, David Piwnica-Worms, MD PhD

Blood (2006) 108 (11): 2377.

https://doi.org/10.1182/blood.V108.11.2377.2377

Published: 2006

Journal Articles

Comparison of Human Stem Cell Homing after Intravenous or Intra-Femoral Transplantation Using Multimodal In Vivo Imaging of Repopulating Human CD34+ Cells Labeled with Far-Red Fluorescent-Conjugated Nanoparticles.

Jesper Bonde, PhD, David A. Hess, PhD, Dustin J. Maxwell, PhD, Ryan Lahey, BS, Michael H. Creer, MD, David Piwnica-Worms, PhD, Jan A. Nolta, PhD

Blood (2005) 106 (11): 2196.

https://doi.org/10.1182/blood.V106.11.2196.2196

Published: 2005

Journal Articles

Comparison of the Proliferative Kinetics, GVHD Potential and GCV Sensitivity of Naive and Transduced and Selected Murine T Cells after Allogeneic BMT.

Michael Rettig, PhD, Julie Ritchey, Julie Prior, David Piwnica-Worms, MD/PhD, Mark Bonyhadi, PhD, John DiPersio, MD/PhD.

Blood (2005) 106 (11): 5257.

https://doi.org/10.1182/blood.V106.11.5257.5257

Published: 2005

Journal Articles

In Vivo Imaging and Tracking of Defined, Repopulating Human Stem Cell Subsets Using Fluorescence Conjugated Nanoparticles in a Clinically Applicable Ex Vivo Protocol.

Jesper Bonde, PhD, Dustin J. Maxwell, PhD, David A. Hess, PhD, Ryan Lahey, BS, Michael H. Creer, MD, David Piwnica-Worms, PhD, Jan A. Nolta, PhD

Blood (2005) 106 (11): 3031.

https://doi.org/10.1182/blood.V106.11.3031.3031

Published: 2005

NARROW

IFNγR Signaling As a Therapeutic Target To Prevent GvHD While Preserving Gvl

Interruption of IFNγR Signaling Results in Altered T Cell Trafficking in Vivo and Abrogation of GvHD While Maintaining a Robust Gvl Response

IFNγR signaling mediates alloreactive T-cell trafficking and GVHD

Epoxyketone-Based Proteasome Inhibitors Carfilzomib and Orally Bioavailable ONX 0912 Have Anti-Resorptive and Bone-Anabolic Activity in Addition to Anti-Myeloma Effects

Interruption of the IFN γR/CXCR3 Axis Results in Altered T Cell Trafficking In Vivo and Abrogation of GvHD While Maintaining a Robust Gvl Response

Effect of In Vivo Azacitidine on GvHD and Gvl: Mechanistic Studies

Chemosensitization of acute myeloid leukemia (AML) following mobilization by the CXCR4 antagonist AMD3100

Revascularization of ischemic limbs after transplantation of human bone marrow cells with high aldehyde dehydrogenase activity

Imaging spontaneous tumorigenesis: inflammation precedes development of peripheral NK tumors

Human Cord Blood Progenitors with High Aldehyde Dehydrogenase Activity Improve Vascular Density in a Model of Acute Myocardial Infarction

IL-12 Stimulates Interferon-Gamma Mediated Inhibition of Tumor-Induced Regulatory T Cell Proliferation and Enhances Tumor Clearance

Fluorophore Conjugated Iron Oxide Nanoparticle Labeling and Analysis of Engrafting Human Hematopoietic Stem Cells.

Granulocyte colony-stimulating factor enhances bone tumor growth in mice in an osteoclast-dependent manner

In Vivo Bioluminescence Imaging (BLI) and Sequential 18 F]FHBG microPET Imaging Studies of Human T Cell (huT) Trafficking, Expansion and Xenogeneic Graft-Versus-Host-Disease (XGVHD) Following Different Routes of T Cell Administration.

CXCR4/SDF-1 Is a Key Regulator for Leukemia Migration and Homing to the BM: Impact of AMD3100 on In Vivo Response to Chemotherapy.

Granzyme B Is Important for Treg-Mediated Suppression of NK-Dependent Tumor Clearance In Vivo .

Bioluminescence Imaging of Spontaneous Lymphomas and Contribution of Distinct NFκB Pathways.

Comparison of Human Stem Cell Homing after Intravenous or Intra-Femoral Transplantation Using Multimodal In Vivo Imaging of Repopulating Human CD34+ Cells Labeled with Far-Red Fluorescent-Conjugated Nanoparticles.

Comparison of the Proliferative Kinetics, GVHD Potential and GCV Sensitivity of Naive and Transduced and Selected Murine T Cells after Allogeneic BMT.

In Vivo Imaging and Tracking of Defined, Repopulating Human Stem Cell Subsets Using Fluorescence Conjugated Nanoparticles in a Clinically Applicable Ex Vivo Protocol.

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American Society of Hematology

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American Society of Hematology

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