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Journal Articles

Polygenic Germline Risk of Common Haematological Traits Drives Clonal Selection on JAK2 V617F and Development of Myeloproliferative Neoplasms

Jyoti Nangalia, Jing Guo, Klaudia Walter, Pedro Quiros, Muxin Gu, E Joanna Baxter, John Danesh, Emanuele Di Angelantonio, David Roberts, Paola Guglielmelli, Claire N Harrison, Anna L Godfrey, Anthony R Green, George Vassiliou, Dragana Vuckovic, Nicole Soranzo

Blood (2023) 142 (Supplement 1): 863.

https://doi.org/10.1182/blood-2023-189551

Published: 2023

Journal Articles

Pervasive Positive Selection in Blood in 200,618 Individuals and Novel Drivers of Clonal Hematopoiesis

Nicholas Bernstein, Michael Spencer Chapman, Kudzai Nyamondo, Zhenghao Chen, Nicholas Williams, Emily Mitchell, Peter Campbell, Robert L Cohen, Jyoti Nangalia

Blood (2023) 142 (Supplement 1): 4062.

https://doi.org/10.1182/blood-2023-185188

Published: 2023

Journal Articles

Cancer Chemotherapy Accelerates the Loss of Clonal Diversity in Hematopoietic Stem Cells and Promotes the Convergent Evolution of Therapy-Related Clonal Hematopoiesis

Blood (2022) 140 (Supplement 1): 2232–2233.

https://doi.org/10.1182/blood-2022-160294

Published: 2022

Journal Articles

Clonal Hematopoiesis in Mice Is Common with Age and Accelerated By Microbial Exposure

Chiraag D. Kapadia, Matthew Yousefzadeh, Emily Mitchell, Duy Le, Nicholas Williams, Marcus A. Florez, Katherine Y. King, Laura Niedernhofer, Jyoti Nangalia, Margaret A. Goodell

Blood (2022) 140 (Supplement 1): 5741–5742.

https://doi.org/10.1182/blood-2022-168231

Published: 2022

Journal Articles

Ruxolitinib Versus Best Available Therapy for PV Intolerant or Resistant to Hydroxycarbamide in a Randomized Trial

Blood (2022) 140 (Supplement 1): 1781–1783.

https://doi.org/10.1182/blood-2022-157273

Published: 2022

Journal Articles

Clonal Dynamics after Haematopoietic Stem Cell Transplantation Using Genome-Wide Somatic Mutations

Michael Spencer Chapman, C. Matthias Wilk, Steffen Boettcher, Emily Mitchell, Kevin J Dawson, Larisa V. Kovtonyuk, Jan Müller, Nicholas Williams, Jyoti Nangalia, Markus G Manz, Peter J. Campbell

Blood (2022) 140 (Supplement 1): 1572–1573.

https://doi.org/10.1182/blood-2022-166701

Published: 2022

Journal Articles

The Longitudinal Dynamics and Natural History of Clonal Hematopoiesis

Blood (2021) 138 (Supplement 2): LBA-2.

https://doi.org/10.1182/blood-2021-154938

Published: 2021

Journal Articles

Long-Term Clonal Dynamics upon Allogeneic Haematopoietic Stem Cell Transplantation Revealed Using Somatic Mutations As Clonal Tracking Marks in HSC Donor and Recipient Pairs

Michael Spencer Chapman, C. Matthias Wilk, Steffen Boettcher, Larisa V. Kovtonyuk, Emily Mitchell, Nicholas Williams, Jyoti Nangalia, Markus G Manz, Peter J. Campbell

Blood (2021) 138 (Supplement 1): 3813.

https://doi.org/10.1182/blood-2021-146151

Published: 2021

Journal Articles

Clonal Dynamics of Normal Haematopoiesis with Human Ageing

Blood (2021) 138 (Supplement 1): 598.

https://doi.org/10.1182/blood-2021-150152

Published: 2021

Journal Articles

Changes in Clonal Architecture Inform MPN Disease Course in Advance of Phenotypic Manifestations

Joe S Lee, Nicholas Williams, Joanna E Baxter, Anna L Godfrey, Kate Milne, Karim Mane, David C Wedge, Peter J. Campbell, Anthony R Green, Jyoti Nangalia

Blood (2021) 138 (Supplement 1): 3590.

https://doi.org/10.1182/blood-2021-152436

Published: 2021

Journal Articles

Inherited Blood Cancer Predisposition through Altered Transcription Elongation

Liam Cato, Jiawei Zhao, Erik L. Bao, Samuel Bryant, Nicholas Williams, Yuemeng Jia, Jyoti Nangalia, Michael Erb, Seychelle Vos, Scott A. Armstrong, Vijay G. Sankaran

Blood (2021) 138 (Supplement 1): 629.

https://doi.org/10.1182/blood-2021-153381

Published: 2021

Journal Articles

Clonal hematopoiesis and therapy-related myeloid neoplasms following neuroblastoma treatment

Tim H. H. Coorens, Grace Collord, Wanhua Lu, Emily Mitchell, Jannat Ijaz, Thomas Roberts, Thomas R. W. Oliver, G. A. Amos Burke, Michael Gattens, Emmy Dickens, Jyoti Nangalia, Marc Tischkowitz, John Anderson, Adam Shlien, Anna L. Godfrey, Matthew J. Murray, Sam Behjati

Blood (2021) 137 (21): 2992–2997.

https://doi.org/10.1182/blood.2020010150

Published: 2021

Includes: Supplemental data

Journal Articles

Driver Mutation Acquisition in Utero and Childhood Followed By Lifelong Clonal Evolution Underlie Myeloproliferative Neoplasms

Nicholas Williams, PhD, Joe Lee, MBBS, Luiza Moore, PhD, Joanna E Baxter, PhD, James Hewinson, PhD, Kevin J Dawson, PhD, Andrew Menzies, MSc, Anna L Godfrey, PhD, Anthony R Green, PhDFRCPath FMedSci, Peter J Campbell, PhD, Jyoti Nangalia, MBBChir

Blood (2020) 136 (Supplement_2): LBA-1.

https://doi.org/10.1182/blood-2020-143813

Published: 2020

Journal Articles

Clonal approaches to understanding the impact of mutations on hematologic disease development

Jyoti Nangalia, Emily Mitchell, Anthony R. Green

Blood (2019) 133 (13): 1436–1445.

https://doi.org/10.1182/blood-2018-11-835405

Published: 2019

Journal Articles

Hydroxycarbamide Plus Aspirin Vs Aspirin Alone in Intermediate Risk Essential Thrombocythemia: Results of the PT-1 International, Prospective, Randomized Clinical Trial

Anna L. Godfrey, BMBCh, PhD MRCP, FRCPath, Peter J Campbell, MD PhD, Cathy MacLean, BSc, MSc, MBA, Georgina Buck, BSc, MSc, Clare L. East, BSc, Julia Cook, BSc, Julie Temple, BSc, Bridget S. Wilkins, MD FRCPath, Keith Wheatley, DPhil, Jyoti Nangalia, MBBChir, MA, MRCP, FRCPath, PhD, Jacob Grinfeld, MBChB, BSc, MRCP, FRCPath, Mary Frances Frances McMullin, MB,Bch BAO, MD FRCPath, Cecily Forsyth, MB BS, Jean-Jacques Kiladjian, MD PhD, Anthony R. Green, FRCP, FRCPath, FMed Sci, Claire N. Harrison, BMBCh, DM, FRCP, FRCPath

Blood (2017) 130 (Supplement 1): 319.

https://doi.org/10.1182/blood.V130.Suppl_1.319.319

Published: 2017

Journal Articles

Personalized Prognostic Predictions for Patients with Myeloproliferative Neoplasms through Integration of Comprehensive Genomic and Clinical Information

Blood (2017) 130 (Supplement 1): 491.

https://doi.org/10.1182/blood.V130.Suppl_1.491.491

Published: 2017

Journal Articles

A Knowledge-Based Approach for Clinical Annotation of Oncogenic Variants to Support Patient-Tailored Diagnosis in Myeloid Disease

Blood (2017) 130 (Supplement 1): 1414.

https://doi.org/10.1182/blood.V130.Suppl_1.1414.1414

Published: 2017

Journal Articles

Myeloproliferative neoplasms: from origins to outcomes

Jyoti Nangalia, Anthony R. Green

Blood (2017) 130 (23): 2475–2483.

https://doi.org/10.1182/blood-2017-06-782037

Published: 2017

Journal Articles

Relationship of JAK2 V617F Allelic Burden (AB) to Demographics, Disease Characteristics, and Response to Therapy in Persist-1, a Randomized Phase III Study of Pacritinib (PAC) Versus Best Available Therapy (BAT) in Patients (pts) with Primary and Secondary Myelofibrosis (MF)

Alessandro M. Vannucchi, Adam Mead, Miklos Egyed, Anita Szoke, Aleksandr Suvorov, Andrew Perkins, Jiri Mayer, Peter Ganly, Harry C. Schouten, Patrizia Tosi, Charles Michael Farber, Pierre Zachee, Jean-Jacques Kiladjian, Jyoti Nangalia, James P. Dean, Huafeng Zhou, Jack W. Singer, Ruben A. Mesa, Claire N. Harrison

Blood (2016) 128 (22): 3131.

https://doi.org/10.1182/blood.V128.22.3131.3131

Published: 2016

Journal Articles

Nongenetic stochastic expansion of JAK2V617F -homozygous subclones in polycythemia vera?

Anna L. Godfrey, Jyoti Nangalia, E. Joanna Baxter, Charles E. Massie, David G. Kent, Elli Papaemmanuil, Peter J. Campbell, Anthony R. Green

Blood (2014) 124 (22): 3332–3334.

https://doi.org/10.1182/blood-2014-09-603043

Published: 2014

Includes: Supplemental data

NARROW

Polygenic Germline Risk of Common Haematological Traits Drives Clonal Selection on JAK2 V617F and Development of Myeloproliferative Neoplasms

Pervasive Positive Selection in Blood in 200,618 Individuals and Novel Drivers of Clonal Hematopoiesis

Cancer Chemotherapy Accelerates the Loss of Clonal Diversity in Hematopoietic Stem Cells and Promotes the Convergent Evolution of Therapy-Related Clonal Hematopoiesis

Clonal Hematopoiesis in Mice Is Common with Age and Accelerated By Microbial Exposure

Ruxolitinib Versus Best Available Therapy for PV Intolerant or Resistant to Hydroxycarbamide in a Randomized Trial

Clonal Dynamics after Haematopoietic Stem Cell Transplantation Using Genome-Wide Somatic Mutations

The Longitudinal Dynamics and Natural History of Clonal Hematopoiesis

Long-Term Clonal Dynamics upon Allogeneic Haematopoietic Stem Cell Transplantation Revealed Using Somatic Mutations As Clonal Tracking Marks in HSC Donor and Recipient Pairs

Clonal Dynamics of Normal Haematopoiesis with Human Ageing

Changes in Clonal Architecture Inform MPN Disease Course in Advance of Phenotypic Manifestations

Inherited Blood Cancer Predisposition through Altered Transcription Elongation

Clonal hematopoiesis and therapy-related myeloid neoplasms following neuroblastoma treatment

Driver Mutation Acquisition in Utero and Childhood Followed By Lifelong Clonal Evolution Underlie Myeloproliferative Neoplasms

Clonal approaches to understanding the impact of mutations on hematologic disease development

Hydroxycarbamide Plus Aspirin Vs Aspirin Alone in Intermediate Risk Essential Thrombocythemia: Results of the PT-1 International, Prospective, Randomized Clinical Trial

Personalized Prognostic Predictions for Patients with Myeloproliferative Neoplasms through Integration of Comprehensive Genomic and Clinical Information

A Knowledge-Based Approach for Clinical Annotation of Oncogenic Variants to Support Patient-Tailored Diagnosis in Myeloid Disease

Myeloproliferative neoplasms: from origins to outcomes

Relationship of JAK2 V617F Allelic Burden (AB) to Demographics, Disease Characteristics, and Response to Therapy in Persist-1, a Randomized Phase III Study of Pacritinib (PAC) Versus Best Available Therapy (BAT) in Patients (pts) with Primary and Secondary Myelofibrosis (MF)

Nongenetic stochastic expansion of JAK2V617F -homozygous subclones in polycythemia vera?

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American Society of Hematology

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ASH Publications

American Society of Hematology

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