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Journal Articles

The lifelong natural history of clonal hematopoiesis and its links to myeloid neoplasia

Margarete A. Fabre, George S. Vassiliou

Blood (2024) 143 (7): 573–581.

https://doi.org/10.1182/blood.2023019964

Published: 2024

Journal Articles

Prevalence and significance of DDX41 gene variants in the general population

Sruthi Cheloor Kovilakam, Muxin Gu, William G. Dunn, Ludovica Marando, Clea Barcena, Serena Nik-Zainal, Irina Mohorianu, Siddhartha P. Kar, Margarete A. Fabre, Pedro M. Quiros, George S. Vassiliou

Blood (2023) 142 (14): 1185–1192.

https://doi.org/10.1182/blood.2023020209

Published: 2023

Includes: Supplemental data

Journal Articles

HOXA9 forms a repressive complex with nuclear matrix–associated protein SAFB to maintain acute myeloid leukemia

Shuchi Agrawal-Singh, Jaana Bagri, George Giotopoulos, Dhoyazan M. A. Azazi, Sarah J. Horton, Cecile K. Lopez, Shubha Anand, Anne-Sophie Bach, Frances Stedham, Robin Antrobus, Jack W. Houghton, George S. Vassiliou, Daniel Sasca, Haiyang Yun, Anthony D. Whetton, Brian J. P. Huntly

Blood (2023) 141 (14): 1737–1754.

https://doi.org/10.1182/blood.2022016528

Published: 2023

Includes: Supplemental data

Journal Articles

Genome-Wide CRISPR Screen Reveals Dependency of PPM1D- mutant Cells on DNA Repair

Linda Zhang, Joanne I. Hsu, Etienne D. Braekeleer, Hidetaka Uryu, Elsa Callen-Moreu, Andre Nussenzweig, Koichi Takahashi, George S Vassiliou, Margaret A. Goodell

Blood (2022) 140 (Supplement 1): 1994–1995.

https://doi.org/10.1182/blood-2022-166910

Published: 2022

Journal Articles

A macaque clonal hematopoiesis model demonstrates expansion of TET2-disrupted clones and utility for testing interventions

Blood (2022) 140 (16): 1774–1789.

https://doi.org/10.1182/blood.2021014875

Published: 2022

Includes: Supplemental data

Journal Articles

STAT1 is essential for HSC function and maintains MHCII hi stem cells that resist myeloablation and neoplastic expansion

Blood (2022) 140 (14): 1592–1606.

https://doi.org/10.1182/blood.2021014009

Published: 2022

Includes: Supplemental data

Journal Articles

Clonal hematopoiesis is not significantly associated with COVID-19 disease severity

Blood (2022) 140 (14): 1650–1655.

https://doi.org/10.1182/blood.2022015721

Published: 2022

Includes: Supplemental data

Journal Articles

The Longitudinal Dynamics and Natural History of Clonal Hematopoiesis

Blood (2021) 138 (Supplement 2): LBA-2.

https://doi.org/10.1182/blood-2021-154938

Published: 2021

Journal Articles

Clinical relevance of clonal hematopoiesis in persons aged ≥80 years

Marianna Rossi, Manja Meggendorfer, Matteo Zampini, Mauro Tettamanti, Emma Riva, Erica Travaglino, Matteo Bersanelli, Sara Mandelli, Alessia Antonella Galbussera, Ettore Mosca, Elena Saba, Chiara Chiereghin, Nicla Manes, Chiara Milanesi, Marta Ubezio, Lucio Morabito, Clelia Peano, Giulia Soldà, Rosanna Asselta, Stefano Duga, Carlo Selmi, Maria De Santis, Karolina Malik, Giulia Maggioni, Marilena Bicchieri, Alessia Campagna, Cristina A. Tentori, Antonio Russo, Efrem Civilini, Paola Allavena, Rocco Piazza, Giovanni Corrao, Claudia Sala, Alberto Termanini, Laura Giordano, Paolo Detoma, Aurelio Malabaila, Luca Sala, Stefano Rosso, Roberto Zanetti, Claudia Saitta, Elena Riva, Gianluigi Condorelli, Francesco Passamonti, Armando Santoro, Francesc Sole, Uwe Platzbecker, Pierre Fenaux, Niccolò Bolli, Gastone Castellani, Wolfgang Kern, George S. Vassiliou, Torsten Haferlach, Ugo Lucca, Matteo G. Della Porta

Blood (2021) 138 (21): 2093–2105.

https://doi.org/10.1182/blood.2021011320

Published: 2021

Includes: Supplemental data

Journal Articles

Mannose Metabolism Is a Metabolic Vulnerability Unveiled By Standard and Novel Therapies in Acute Myeloid Leukemia

Keith Woodley, Laura S Dillingh, George Giotopoulos, Pedro Madrigal, Konstantinos Tzelepis, Celine Philippe, Kevin Rattigan, Ryan Asby, Vilma Dembitz, Aoife S.M. Magee, Gudmundur Helgason, Kevin Rouault-Pierre, George S. Vassiliou, Brian J.P Huntly, Paolo Gallipoli

Blood (2021) 138 (Supplement 1): 508.

https://doi.org/10.1182/blood-2021-148489

Published: 2021

Journal Articles

Combinatorial Genetic Uncovers DOCK1/RAC2 As Specific Targets for the Treatment of NPM1;Cohesin Mutated AML

Alison E Meyer, Cary Stelloh, Kirthi Pulakanti, Robert Burns, Joseph B Fisher, Katelyn E Heimbruch, Sergey Tarima, Aaron D Viny, George S. Vassiliou, Sridhar Rao

Blood (2021) 138 (Supplement 1): 3288.

https://doi.org/10.1182/blood-2021-148811

Published: 2021

Journal Articles

Clonal Dynamics of Normal Haematopoiesis with Human Ageing

Blood (2021) 138 (Supplement 1): 598.

https://doi.org/10.1182/blood-2021-150152

Published: 2021

Journal Articles

Synergistic targeting of FLT3 mutations in AML via combined menin-MLL and FLT3 inhibition

Margarita M. Dzama, Marlene Steiner, Johanna Rausch, Daniel Sasca, Jonas Schönfeld, Kerstin Kunz, Martha C. Taubert, Gerard M. McGeehan, Chun-Wei Chen, Annalisa Mupo, Patricia Hähnel, Matthias Theobald, Thomas Kindler, Richard P. Koche, George S. Vassiliou, Scott A. Armstrong, Michael W. M. Kühn

Blood (2020) 136 (21): 2442–2456.

https://doi.org/10.1182/blood.2020005037

Published: 2020

Includes: Supplemental data

Journal Articles

TET2 and DNMT3A Mutations Exert Divergent Effects on DNA Repair and Sensitivity of Leukemia Cells to PARP Inhibitors

Blood (2020) 136 (Supplement 1): 4.

https://doi.org/10.1182/blood-2020-137658

Published: 2020

Journal Articles

Transcriptional Heterogeneity Governs Cell Fate Diversification during Pre-Leukemia to Leukemia Progression

Shikha Gupta, MS, Ana Filipa Domingues, Oliwia Cyran, George Giotopoulos, PhD, Sudhakaran Prabakaran, PhD, Brian J. P. Huntly, PhD MRCP, MB, FRCPath, Oliver M. Dovey, PhD, George S. Vassiliou, MD PhD FRCPath, MRCP, Cristina Pina, MDDPhil

Blood (2020) 136 (Supplement 1): 31–32.

https://doi.org/10.1182/blood-2020-136504

Published: 2020

Journal Articles

Setbp1 Overexpression Acts in the Place of Class-Defining Somatic Mutations to Drive Mouse and Human FLT3-ITD -Mutant AMLs

Suruchi Pacharne, Oliver M. Dovey, PhD, Jonathan L Cooper, Muxin Gu, Vijay Baskar, PhD, Mathias J Friedrich, Malgorzata Gozdecka, PhD, Sandeep S Rajan, PhD, Etienne De Braekeleer, PhD MSc, Maxim Barenboim, Grace Collord, Hannes Postingl, PhD, Ruben Bautista, Milena Mazan, PhD, Roland Rad, Prof., MD, Konstantinos Tzelepis, Penny Wright, George S. Vassiliou, MD PhD FRCPath, MRCP

Blood (2020) 136 (Supplement 1): 31–32.

https://doi.org/10.1182/blood-2020-141743

Published: 2020

Journal Articles

Home and away: clonal hematopoiesis in sibling transplants

Margarete A. Fabre, George S. Vassiliou

Blood (2020) 135 (18): 1511–1512.

https://doi.org/10.1182/blood.2020005717

Published: 2020

Journal Articles

Concordance for clonal hematopoiesis is limited in elderly twins

Margarete A. Fabre, Thomas McKerrell, Maximillian Zwiebel, M. S. Vijayabaskar, Naomi Park, Philippa M. Wells, Roland Rad, Panagiotis Deloukas, Kerrin Small, Claire J. Steves, George S. Vassiliou

Blood (2020) 135 (4): 269–273.

https://doi.org/10.1182/blood.2019001807

Published: 2020

Includes: Supplemental data

Journal Articles

The curious incident of TdT-mediated mutations in AML

George S. Vassiliou

Blood (2019) 134 (25): 2229–2231.

https://doi.org/10.1182/blood.2019003619

Published: 2019

Journal Articles

Pharmacological Inhibition of the RNA m 6 a Writer METTL3 As a Novel Therapeutic Strategy for Acute Myeloid Leukemia

Konstantinos Tzelepis, Etienne De Braekeleer, PhD MSc, Eliza Yankova, PhD, Justyna Rak, PhD, Demetrios Aspris, MSc, Ana Filipa Domingues, PhD, Richard Fosbeary, Alan Hendrick, PhD, Dan Leggate, PhD, Yaara Ofir-Rosenfeld, PhD, Alexandra Sapetschnig, PhD, Cristina Pina, MDDPhil, Mark Albertella, PhD, Wesley Blackaby, PhD, Oliver Rausch, PhD, George S. Vassiliou, FRCPath, MRCP, PhD, Tony Kouzarides, PhD

Blood (2019) 134 (Supplement_1): 403.

https://doi.org/10.1182/blood-2019-127962

Published: 2019

NARROW

The lifelong natural history of clonal hematopoiesis and its links to myeloid neoplasia

Prevalence and significance of DDX41 gene variants in the general population

HOXA9 forms a repressive complex with nuclear matrix–associated protein SAFB to maintain acute myeloid leukemia

Genome-Wide CRISPR Screen Reveals Dependency of PPM1D- mutant Cells on DNA Repair

A macaque clonal hematopoiesis model demonstrates expansion of TET2-disrupted clones and utility for testing interventions

STAT1 is essential for HSC function and maintains MHCII hi stem cells that resist myeloablation and neoplastic expansion

Clonal hematopoiesis is not significantly associated with COVID-19 disease severity

The Longitudinal Dynamics and Natural History of Clonal Hematopoiesis

Clinical relevance of clonal hematopoiesis in persons aged ≥80 years

Mannose Metabolism Is a Metabolic Vulnerability Unveiled By Standard and Novel Therapies in Acute Myeloid Leukemia

Combinatorial Genetic Uncovers DOCK1/RAC2 As Specific Targets for the Treatment of NPM1;Cohesin Mutated AML

Clonal Dynamics of Normal Haematopoiesis with Human Ageing

Synergistic targeting of FLT3 mutations in AML via combined menin-MLL and FLT3 inhibition

TET2 and DNMT3A Mutations Exert Divergent Effects on DNA Repair and Sensitivity of Leukemia Cells to PARP Inhibitors

Transcriptional Heterogeneity Governs Cell Fate Diversification during Pre-Leukemia to Leukemia Progression

Setbp1 Overexpression Acts in the Place of Class-Defining Somatic Mutations to Drive Mouse and Human FLT3-ITD -Mutant AMLs

Home and away: clonal hematopoiesis in sibling transplants

Concordance for clonal hematopoiesis is limited in elderly twins

The curious incident of TdT-mediated mutations in AML

Pharmacological Inhibition of the RNA m 6 a Writer METTL3 As a Novel Therapeutic Strategy for Acute Myeloid Leukemia

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American Society of Hematology

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ASH Publications

American Society of Hematology

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