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Journal Articles

IL-1 in aging and pathologies of hematopoietic stem cells

Francisco Caiado, Markus G. Manz

Blood (2024) 144 (4): 368–377.

https://doi.org/10.1182/blood.2023023105

Published: 2024

Includes: Supplemental data

Journal Articles

Efficient Combinatorial Adaptor-Mediated Targeting of Acute Myeloid Leukemia with CAR T-Cells

Laura Volta, Renier Myburgh, Christian Pellegrino, Christian Koch, Monique Maurer, Francesco Manfredi, Mara Hofstetter, Anne Kaiser, Florin Schneiter, Jan Müller, Marco M. Bühler, Roberto De Luca, Nicholas Favalli, Chiara F. Magnani, Timm Schroeder, Dario Neri, Markus G. Manz

Blood (2023) 142 (Supplement 1): 3435.

https://doi.org/10.1182/blood-2023-185853

Published: 2023

Journal Articles

Preclinical Evaluation of the Efficacy of Human Sirpα Antibodies for B-Cell Lymphoma Immunotherapy in Humanized Mouse Models

Yasuyuki Saito, Afroj Tania, Satomi Komori, Tomoko Takai, Okechi S Oduori, Takenori Kotani, Yohei Funakoshi, Yoji Murata, Kimikazu Yakushijin, Hiroshi Matsuoka, Hironobu Minami, Markus G. Manz, Takashi Matozaki

Blood (2023) 142 (Supplement 1): 1646.

https://doi.org/10.1182/blood-2023-181926

Published: 2023

Journal Articles

Prognostic Value of Measurable Residual Disease in High-Risk Myelodysplastic Syndromes with Intensive Chemotherapy Treatment: Analysis of HOVON-SAKK Studies

Blood (2023) 142 (Supplement 1): 323.

https://doi.org/10.1182/blood-2023-184703

Published: 2023

Journal Articles

TP53 Deficiency in AML Confers Resistance to CAR T-Cells That Can be Overcome By Targeting the Cholesterol or Wnt Pathways

Jan Mueller, Roman Schimmer, Christian Koch, Florin Schneiter, Jonas Fullin, Veronika Lysenko, Renier Myburgh, Laura Volta, Alexandre Theocharides, Kari Kurppa, Benjamin L. Ebert, Timm Schroeder, Markus G. Manz, Steffen Boettcher

Blood (2023) 142 (Supplement 1): 1019.

https://doi.org/10.1182/blood-2023-185567

Published: 2023

Journal Articles

The Laip-Based-Dfn Approach Is Superior in Terms of Useful MRD Results As Compared to the Laip Approach after Cycle II in Acute Myeloid Leukemia

Blood (2023) 142 (Supplement 1): 1572.

https://doi.org/10.1182/blood-2023-181709

Published: 2023

Journal Articles

Prospective validation of the prognostic relevance of CD34 + CD38 – AML stem cell frequency in the HOVON-SAKK132 trial

Blood (2023) 141 (21): 2657–2661.

https://doi.org/10.1182/blood.2022019160

Published: 2023

Includes: Supplemental data

Journal Articles

Aging drives Tet2 +/− clonal hematopoiesis via IL-1 signaling

Francisco Caiado, Larisa V. Kovtonyuk, Nagihan G. Gonullu, Jonas Fullin, Steffen Boettcher, Markus G. Manz

Blood (2023) 141 (8): 886–903.

https://doi.org/10.1182/blood.2022016835

Published: 2023

Includes: Supplemental data

Journal Articles

Measurable Residual Disease Guided Therapy in Intermediate-Risk AML Patients Compared to an Unguided Cohort Using Propensity Score Matching

Jesse M. Tettero, Lok Lam Ngai, Costa Bachas, Dimitri A. Breems, Thomas Fischer, Bjørn Tore Gjertsen, Patrycja Gradowska, Laimonas Griskevicius, Jeroen J.W.M. Janssen, Gunnar Juliusson, Johan A. Maertens, Markus G Manz, Thomas Pabst, Jakob Passweg, Kimmo Porkka, Peter JM Valk, Bob Lowenberg, Gert J. Ossenkoppele, Jacqueline Cloos

Blood (2022) 140 (Supplement 1): 2027–2029.

https://doi.org/10.1182/blood-2022-157009

Published: 2022

Journal Articles

Prospective Validation of CD34+CD38- Leukemic Stem Cell Frequency in the HOVON-SAKK 132 Trial: Perspectives for Future Improvements

Blood (2022) 140 (Supplement 1): 9125–9127.

https://doi.org/10.1182/blood-2022-157753

Published: 2022

Journal Articles

Bayesian Inference for Optimization of Interim Analysis in Clinical Trials By Incorporation of Historical Data: Reanalysis of the HOVON AML 132 Clinical Trial

Niek Van Der Maas, Kazem Nasserinejad, Thomas Pabst, Johan A. Maertens, Dimitri A. Breems, Markus G Manz, Jacqueline Cloos, Gert J. Ossenkoppele, Yngvar Floisand, Patrycja Gradowska, Bob Lowenberg, Gerwin A. Huls, Douwe Postmus, Francesco Pignatti, Jan J. Cornelissen, Jurjen Versluis

Blood (2022) 140 (Supplement 1): 127–129.

https://doi.org/10.1182/blood-2022-158137

Published: 2022

Journal Articles

CAR T Cells and Their Immune Environment Synergize to Shape Distinct Immune Profiles in Response Versus Toxicity in B Cell Lymphoma Patients

Stefanie Kreutmair, Maximilian M Schaefer, Sebastian Stolz, Carla Merten, Can Ulutekin, Florian Ingelfinger, Susanne Unger, Chiara Alberti, Tobias Wertheimer, Aakriti Sethi, Thorsten Zenz, Markus G Manz, Antonia Maria Susanne Müller, Corinne C Widmer, Burkhard Becher

Blood (2022) 140 (Supplement 1): 7504–7505.

https://doi.org/10.1182/blood-2022-168905

Published: 2022

Journal Articles

Clonal Dynamics after Haematopoietic Stem Cell Transplantation Using Genome-Wide Somatic Mutations

Michael Spencer Chapman, C. Matthias Wilk, Steffen Boettcher, Emily Mitchell, Kevin J Dawson, Larisa V. Kovtonyuk, Jan Müller, Nicholas Williams, Jyoti Nangalia, Markus G Manz, Peter J. Campbell

Blood (2022) 140 (Supplement 1): 1572–1573.

https://doi.org/10.1182/blood-2022-166701

Published: 2022

Journal Articles

TLR1/2-stimulated DCs “prime” HSCs via IL-1β

Francisco Caiado, Markus G. Manz

Blood (2022) 140 (14): 1576–1578.

https://doi.org/10.1182/blood.2022017137

Published: 2022

Journal Articles

Asymmetric organelle inheritance predicts human blood stem cell fate

Dirk Loeffler, Florin Schneiter, Weijia Wang, Arne Wehling, Tobias Kull, Claudia Lengerke, Markus G. Manz, Timm Schroeder

Blood (2022) 139 (13): 2011–2023.

https://doi.org/10.1182/blood.2020009778

Published: 2022

Includes: Multimedia, Supplemental data

Journal Articles

IL-1 mediates microbiome-induced inflammaging of hematopoietic stem cells in mice

Larisa V. Kovtonyuk, Francisco Caiado, Santiago Garcia-Martin, Eva-Maria Manz, Patrick Helbling, Hitoshi Takizawa, Steffen Boettcher, Fatima Al-Shahrour, Cesar Nombela-Arrieta, Emma Slack, Markus G. Manz

Blood (2022) 139 (1): 44–58.

https://doi.org/10.1182/blood.2021011570

Published: 2022

Includes: Supplemental data

Journal Articles

Anti-CD117 CAR T Cells Incorporating a Safety Switch Eradicate Acute Myeloid Leukemia and Deplete Human Hematopoietic Stem Cells

Chiara F Magnani, Renier Myburgh, Norman F Russkamp, Steve Pascolo, Judith A Shizuru, Dario Neri, Markus G Manz

Blood (2021) 138 (Supplement 1): 2808.

https://doi.org/10.1182/blood-2021-145195

Published: 2021

Journal Articles

Efficient Human Acute Myeloid Leukemia Targeting By Universal Chimeric Antigen Receptor T-Cells Via Combinatorial Use of Linkers

Laura Volta, Renier Myburgh, Christian Edoardo Pellegrino, Jan Müller, C. Matthias Wilk, Dario Neri, Markus G Manz

Blood (2021) 138 (Supplement 1): 2781.

https://doi.org/10.1182/blood-2021-151039

Published: 2021

Journal Articles

CD117 As an Immunotherapeutic Target in Advanced Forms of Mastocytosis

Anne Kaiser, Renier Myburgh, Laura Volta, Christian Edoardo Pellegrino, Markus G Manz

Blood (2021) 138 (Supplement 1): 2538.

https://doi.org/10.1182/blood-2021-145876

Published: 2021

Journal Articles

Long-Term Clonal Dynamics upon Allogeneic Haematopoietic Stem Cell Transplantation Revealed Using Somatic Mutations As Clonal Tracking Marks in HSC Donor and Recipient Pairs

Michael Spencer Chapman, C. Matthias Wilk, Steffen Boettcher, Larisa V. Kovtonyuk, Emily Mitchell, Nicholas Williams, Jyoti Nangalia, Markus G Manz, Peter J. Campbell

Blood (2021) 138 (Supplement 1): 3813.

https://doi.org/10.1182/blood-2021-146151

Published: 2021

NARROW

IL-1 in aging and pathologies of hematopoietic stem cells

Efficient Combinatorial Adaptor-Mediated Targeting of Acute Myeloid Leukemia with CAR T-Cells

Preclinical Evaluation of the Efficacy of Human Sirpα Antibodies for B-Cell Lymphoma Immunotherapy in Humanized Mouse Models

Prognostic Value of Measurable Residual Disease in High-Risk Myelodysplastic Syndromes with Intensive Chemotherapy Treatment: Analysis of HOVON-SAKK Studies

TP53 Deficiency in AML Confers Resistance to CAR T-Cells That Can be Overcome By Targeting the Cholesterol or Wnt Pathways

The Laip-Based-Dfn Approach Is Superior in Terms of Useful MRD Results As Compared to the Laip Approach after Cycle II in Acute Myeloid Leukemia

Prospective validation of the prognostic relevance of CD34 + CD38 – AML stem cell frequency in the HOVON-SAKK132 trial

Aging drives Tet2 +/− clonal hematopoiesis via IL-1 signaling

Measurable Residual Disease Guided Therapy in Intermediate-Risk AML Patients Compared to an Unguided Cohort Using Propensity Score Matching

Prospective Validation of CD34+CD38- Leukemic Stem Cell Frequency in the HOVON-SAKK 132 Trial: Perspectives for Future Improvements

Bayesian Inference for Optimization of Interim Analysis in Clinical Trials By Incorporation of Historical Data: Reanalysis of the HOVON AML 132 Clinical Trial

CAR T Cells and Their Immune Environment Synergize to Shape Distinct Immune Profiles in Response Versus Toxicity in B Cell Lymphoma Patients

Clonal Dynamics after Haematopoietic Stem Cell Transplantation Using Genome-Wide Somatic Mutations

TLR1/2-stimulated DCs “prime” HSCs via IL-1β

Asymmetric organelle inheritance predicts human blood stem cell fate

IL-1 mediates microbiome-induced inflammaging of hematopoietic stem cells in mice

Anti-CD117 CAR T Cells Incorporating a Safety Switch Eradicate Acute Myeloid Leukemia and Deplete Human Hematopoietic Stem Cells

Efficient Human Acute Myeloid Leukemia Targeting By Universal Chimeric Antigen Receptor T-Cells Via Combinatorial Use of Linkers

CD117 As an Immunotherapeutic Target in Advanced Forms of Mastocytosis

Long-Term Clonal Dynamics upon Allogeneic Haematopoietic Stem Cell Transplantation Revealed Using Somatic Mutations As Clonal Tracking Marks in HSC Donor and Recipient Pairs

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American Society of Hematology

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ASH Publications

American Society of Hematology

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