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Christian Koch
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Journal Articles

Bone marrow failure, somatic rescue by p53 inactivation, and enhanced leukemogenesis in germline ERCC6L2 disease

Available to Purchase
Roman Schimmer, Nancy Klemm, Jonas Fullin, Ebru Topcu, Milena Treacy, Karolina Zielinska, Cyril Doerdelmann, Daphne Devesa-Serrano, Melissa Lock, Francisco Caiado, Christian Koch, Nadjia Dietliker, Rahel Schwotzer, Marco Matteo Buehler, Mikko Myllymäki, Kari J. Kurppa, Markus G. Manz, Massimo Lopes, Steffen Boettcher
Journal: Blood
Blood blood.2025030230.
https://doi.org/10.1182/blood.2025030230
Published: 2026
Includes: Supplemental data
Journal Articles

Modelling the Evolution of Clonal Hematopoiesis to Myeloid Malignancies Under the Selective Pressure of Anti-Cancer Therapy

Free
Christian Koch, Jonas Fullin, Ebru Topçu, Nancy Klemm, Karolina Zielinska, Monika Hebeisen, Joelle Tchinda, Markus G. Manz, Steffen Boettcher
Journal: Blood
Blood (2024) 144 (Supplement 1): 5651.
https://doi.org/10.1182/blood-2024-205797
Published: 2024
Journal Articles

The Pathogenesis of Therapy-Related Myeloid Neoplasms from TP53 -Mutant Clonal Hematopoiesis

Free
Jonas Fullin, Ebru Topçu, Roman R. Schimmer, Nancy Klemm, Karolina Zielinska, Christian Koch, Francisco Caiado, Cyril Doerdelmann, Melissa Lock, Joelle Tchinda, Markus G. Manz, Massimo Lopes, Steffen Boettcher
Journal: Blood
Blood (2024) 144 (Supplement 1): 41.
https://doi.org/10.1182/blood-2024-205209
Published: 2024
Journal Articles

TP53 Deficiency in AML Confers Resistance to CAR T-Cells That Can be Overcome By Targeting the Cholesterol or Wnt Pathways

Free
Jan Mueller, Roman Schimmer, Christian Koch, Florin Schneiter, Jonas Fullin, Veronika Lysenko, Renier Myburgh, Laura Volta, Alexandre Theocharides, Kari Kurppa, Benjamin L. Ebert, Timm Schroeder, Markus G. Manz, Steffen Boettcher
Journal: Blood
Blood (2023) 142 (Supplement 1): 1019.
https://doi.org/10.1182/blood-2023-185567
Published: 2023
Journal Articles

Efficient Combinatorial Adaptor-Mediated Targeting of Acute Myeloid Leukemia with CAR T-Cells

Free
Laura Volta, Renier Myburgh, Christian Pellegrino, Christian Koch, Monique Maurer, Francesco Manfredi, Mara Hofstetter, Anne Kaiser, Florin Schneiter, Jan Müller, Marco M. Bühler, Roberto De Luca, Nicholas Favalli, Chiara F. Magnani, Timm Schroeder, Dario Neri, Markus G. Manz
Journal: Blood
Blood (2023) 142 (Supplement 1): 3435.
https://doi.org/10.1182/blood-2023-185853
Published: 2023