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Journal Articles

Efficient Combinatorial Adaptor-Mediated Targeting of Acute Myeloid Leukemia with CAR T-Cells

Laura Volta, Renier Myburgh, Christian Pellegrino, Christian Koch, Monique Maurer, Francesco Manfredi, Mara Hofstetter, Anne Kaiser, Florin Schneiter, Jan Müller, Marco M. Bühler, Roberto De Luca, Nicholas Favalli, Chiara F. Magnani, Timm Schroeder, Dario Neri, Markus G. Manz

Blood (2023) 142 (Supplement 1): 3435.

https://doi.org/10.1182/blood-2023-185853

Published: 2023

Journal Articles

Single Cell Analysis Identifies Expression of PD-L2 on Human Bone Marrow Hematopoietic Stem Cells

Tessa Schmachtel, Marius Külp, Weijia Yu, Hana Komic, Catia Simoes, Malin S. Nilsson, Felipe Prosper, Timm Schroeder, Halvard Bonig, Bruno Paiva, Fredrik B. Thorén, Michael A. Rieger

Blood (2023) 142 (Supplement 1): 2671.

https://doi.org/10.1182/blood-2023-188684

Published: 2023

Journal Articles

TP53 Deficiency in AML Confers Resistance to CAR T-Cells That Can be Overcome By Targeting the Cholesterol or Wnt Pathways

Jan Mueller, Roman Schimmer, Christian Koch, Florin Schneiter, Jonas Fullin, Veronika Lysenko, Renier Myburgh, Laura Volta, Alexandre Theocharides, Kari Kurppa, Benjamin L. Ebert, Timm Schroeder, Markus G. Manz, Steffen Boettcher

Blood (2023) 142 (Supplement 1): 1019.

https://doi.org/10.1182/blood-2023-185567

Published: 2023

Journal Articles

Iron is a modifier of the phenotypes of JAK2 -mutant myeloproliferative neoplasms

Blood (2023) 141 (17): 2127–2140.

https://doi.org/10.1182/blood.2022017976

Published: 2023

Includes: Supplemental data

Journal Articles

NfκB signaling dynamics and their target genes differ between mouse blood cell types and induce distinct cell behavior

Tobias Kull, Arne Wehling, Martin Etzrodt, Markus Auler, Philip Dettinger, Nicola Aceto, Timm Schroeder

Blood (2022) 140 (2): 99–111.

https://doi.org/10.1182/blood.2021012918

Published: 2022

Includes: Supplemental data

Journal Articles

Asymmetric organelle inheritance predicts human blood stem cell fate

Dirk Loeffler, Florin Schneiter, Weijia Wang, Arne Wehling, Tobias Kull, Claudia Lengerke, Markus G. Manz, Timm Schroeder

Blood (2022) 139 (13): 2011–2023.

https://doi.org/10.1182/blood.2020009778

Published: 2022

Includes: Multimedia, Supplemental data

Journal Articles

Cytokine combinations for human blood stem cell expansion induce cell-type– and cytokine-specific signaling dynamics

Weijia Wang, Yang Zhang, Philip Dettinger, Andreas Reimann, Tobias Kull, Dirk Loeffler, Markus G. Manz, Claudia Lengerke, Timm Schroeder

Blood (2021) 138 (10): 847–857.

https://doi.org/10.1182/blood.2020008386

Published: 2021

Includes: Multimedia, Supplemental data

Journal Articles

JAK2 -V617F and interferon-α induce megakaryocyte-biased stem cells characterized by decreased long-term functionality

Tata Nageswara Rao, Nils Hansen, Jan Stetka, Damien Luque Paz, Milena Kalmer, Julian Hilfiker, Max Endele, Nouraiz Ahmed, Lucia Kubovcakova, Margareta Rybarikova, Hui Hao-Shen, Florian Geier, Christian Beisel, Stefan Dirnhofer, Timm Schroeder, Tim H. Brümmendorf, Dominik Wolf, Steffen Koschmieder, Radek C. Skoda

Blood (2021) 137 (16): 2139–2151.

https://doi.org/10.1182/blood.2020005563

Published: 2021

Includes: Supplemental data

Journal Articles

Adult blood stem cell localization reflects the abundance of reported bone marrow niche cell types and their combinations

Konstantinos D. Kokkaliaris, Leo Kunz, Nina Cabezas-Wallscheid, Constantina Christodoulou, Simon Renders, Fernando Camargo, Andreas Trumpp, David T. Scadden, Timm Schroeder

Blood (2020) 136 (20): 2296–2307.

https://doi.org/10.1182/blood.2020006574

Published: 2020

Includes: Multimedia, Supplemental data

Journal Articles

Single Cell Analysis of the Bone Marrow Niche - Quantitative Understanding of Stem/Progenitor Niche Interactions

Timm Schroeder, PhD

Blood (2020) 136 (Supplement 1): SCI5.

https://doi.org/10.1182/blood-2020-133070

Published: 2020

Journal Articles

Dichotomous Regulation of Lysosomes By MYC and Tfeb Controls Hematopoietic Stem Cell Fate

Laura Garcia Prat, PhD BSc, MSc, Kerstin B Kaufmann, PhD, Florin Schneiter, Veronique Voisin, PhD, Alex Murison, Michelle Chan-Seng-Yue, Olga I. Gan, PhD, Jessica L. McLeod, Michelle Shoong, Kristele Pan, Kinam Gupta, Shin-Ichiro Takayanagi, PhD, Elvin Wagenblast, PhD, Weijia Wang, Timm Schroeder, PhD, Stephanie Zhi-Juan Xie, PhD, John E. Dick, PhD FRS

Blood (2020) 136 (Supplement 1): 34.

https://doi.org/10.1182/blood-2020-142671

Published: 2020

Journal Articles

PU.1 Enforces Hematopoietic Stem Cell Quiescence during Chronic Inflammation

James Chavez, BS, Jennifer L Rabe, BS, BA, Kelly Higa, MS, Dirk Loeffler, Ahmed Nouraiz, PhD, Taylor Mills, BA, Beau M Idler, Brett M. Stevens, PhD, Courtney Fleenor, PhD, Claus Nerlov, PhD, Hideaki Nakajima, MD, James Hagman, Timm Schroeder, PhD, Hyun Min Kim, PhD, Craig T Jordan, PhD, James DeGregori, Eric Pietras, PhD

Blood (2019) 134 (Supplement_1): 822.

https://doi.org/10.1182/blood-2019-129300

Published: 2019

Journal Articles

Understanding cell fate control by continuous single-cell quantification

Dirk Loeffler, Timm Schroeder

Blood (2019) 133 (13): 1406–1414.

https://doi.org/10.1182/blood-2018-09-835397

Published: 2019

Journal Articles

Inflammatory signals directly instruct PU.1 in HSCs via TNF

Martin Etzrodt, Nouraiz Ahmed, Philipp S. Hoppe, Dirk Loeffler, Stavroula Skylaki, Oliver Hilsenbeck, Konstantinos D. Kokkaliaris, Hans-Michael Kaltenbach, Jörg Stelling, Claus Nerlov, Timm Schroeder

Blood (2019) 133 (8): 816–819.

https://doi.org/10.1182/blood-2018-02-832998

Published: 2019

Includes: Supplemental data

Journal Articles

Mouse and human HSPC immobilization in liquid culture by CD43- or CD44-antibody coating

Dirk Loeffler, Weijia Wang, Alois Hopf, Oliver Hilsenbeck, Paul E. Bourgine, Fabian Rudolf, Ivan Martin, Timm Schroeder

Blood (2018) 131 (13): 1425–1429.

https://doi.org/10.1182/blood-2017-07-794131

Published: 2018

Includes: Multimedia, Supplemental data

Journal Articles

CSF-1–induced Src signaling can instruct monocytic lineage choice

Max Endele, Dirk Loeffler, Konstantinos D. Kokkaliaris, Oliver Hilsenbeck, Stavroula Skylaki, Philipp S. Hoppe, Axel Schambach, E. Richard Stanley, Timm Schroeder

Blood (2017) 129 (12): 1691–1701.

https://doi.org/10.1182/blood-2016-05-714329

Published: 2017

Includes: Multimedia, Supplemental data

Journal Articles

Long-term Live Single Cell Quantification of Transcription Factor Dynamics

Timm Schroeder, PhD

Blood (2016) 128 (22): SCI-4.

https://doi.org/10.1182/blood.V128.22.SCI-4.SCI-4

Published: 2016

Journal Articles

Identification of factors promoting ex vivo maintenance of mouse hematopoietic stem cells by long-term single-cell quantification

Konstantinos D. Kokkaliaris, Erin Drew, Max Endele, Dirk Loeffler, Philipp S. Hoppe, Oliver Hilsenbeck, Bernhard Schauberger, Christoph Hinzen, Stavroula Skylaki, Marina Theodorou, Matthias Kieslinger, Ihor Lemischka, Kateri Moore, Timm Schroeder

Blood (2016) 128 (9): 1181–1192.

https://doi.org/10.1182/blood-2016-03-705590

Published: 2016

Includes: Supplemental data

Journal Articles

Glutathione peroxidase 4 prevents necroptosis in mouse erythroid precursors

Özge Canli, Yasemin B. Alankuş, Sasker Grootjans, Naidu Vegi, Lothar Hültner, Philipp S. Hoppe, Timm Schroeder, Peter Vandenabeele, Georg W. Bornkamm, Florian R. Greten

Blood (2016) 127 (1): 139–148.

https://doi.org/10.1182/blood-2015-06-654194

Published: 2016

Includes: Supplemental data

Journal Articles

Interleukin-1 Drives Precocious Myeloid Differentiation of Hematopoietic Stem Cells at the Expense of Self-Renewal

Eric Martin Pietras, PhD, Cristina Mirantes-Barbeito, PhD, Sarah Fong, Dirk Loffler, PhD, Larisa Vladimirovna Kovtonyuk, Ranjani Lakshminarashimhan, Chih Peng Chin, Jose-Marc Techner, Britta Will, PhD, Claus Nerlov, PhD, Ulrich Steidl, MD PhD, Markus Manz, MD, Timm Schroeder, PhD, Emmanuelle Passegue, PhD

Blood (2015) 126 (23): 778.

https://doi.org/10.1182/blood.V126.23.778.778

Published: 2015

NARROW

Efficient Combinatorial Adaptor-Mediated Targeting of Acute Myeloid Leukemia with CAR T-Cells

Single Cell Analysis Identifies Expression of PD-L2 on Human Bone Marrow Hematopoietic Stem Cells

TP53 Deficiency in AML Confers Resistance to CAR T-Cells That Can be Overcome By Targeting the Cholesterol or Wnt Pathways

Iron is a modifier of the phenotypes of JAK2 -mutant myeloproliferative neoplasms

NfκB signaling dynamics and their target genes differ between mouse blood cell types and induce distinct cell behavior

Asymmetric organelle inheritance predicts human blood stem cell fate

Cytokine combinations for human blood stem cell expansion induce cell-type– and cytokine-specific signaling dynamics

JAK2 -V617F and interferon-α induce megakaryocyte-biased stem cells characterized by decreased long-term functionality

Adult blood stem cell localization reflects the abundance of reported bone marrow niche cell types and their combinations

Single Cell Analysis of the Bone Marrow Niche - Quantitative Understanding of Stem/Progenitor Niche Interactions

Dichotomous Regulation of Lysosomes By MYC and Tfeb Controls Hematopoietic Stem Cell Fate

PU.1 Enforces Hematopoietic Stem Cell Quiescence during Chronic Inflammation

Understanding cell fate control by continuous single-cell quantification

Inflammatory signals directly instruct PU.1 in HSCs via TNF

Mouse and human HSPC immobilization in liquid culture by CD43- or CD44-antibody coating

CSF-1–induced Src signaling can instruct monocytic lineage choice

Long-term Live Single Cell Quantification of Transcription Factor Dynamics

Identification of factors promoting ex vivo maintenance of mouse hematopoietic stem cells by long-term single-cell quantification

Glutathione peroxidase 4 prevents necroptosis in mouse erythroid precursors

Interleukin-1 Drives Precocious Myeloid Differentiation of Hematopoietic Stem Cells at the Expense of Self-Renewal

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American Society of Hematology

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ASH Publications

American Society of Hematology

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