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Journal Articles

Ironing erythroid cells takes FLG1 and ERFE to tango

Laura Silvestri

Blood (2024) 143 (13): 1208–1209.

https://doi.org/10.1182/blood.2023023645

Published: 2024

Journal Articles

Iron is a modifier of the phenotypes of JAK2 -mutant myeloproliferative neoplasms

Blood (2023) 141 (17): 2127–2140.

https://doi.org/10.1182/blood.2022017976

Published: 2023

Includes: Supplemental data

Journal Articles

Bone Marrow Tfr2 Deletion Modulates Systemic Metabolism in β-Thalassemic Mice to Sustain Augmented Erythropoiesis

Simona Maria Di Modica, Claudia Benelli, Alessia Pagani, Emanuele Tanzi, Violante Olivari, Laura Silvestri, Antonella Nai

Blood (2022) 140 (Supplement 1): 2197–2198.

https://doi.org/10.1182/blood-2022-163145

Published: 2022

Journal Articles

Rebalancing Iron Homeostasis and Erythropoiesis through Tfr2 Inhibition for Correction of Anemia in CKD

Violante Olivari, Maria Rosa Lidonnici, Mariam Aghajan, Mariateresa Pettinato, Simona Maria Di Modica, Alessia Pagani, Francesca Tiboni, Shuling Guo, Laura Silvestri, Giuliana Ferrari, Antonella Nai

Blood (2021) 138 (Supplement 1): 940.

https://doi.org/10.1182/blood-2021-148384

Published: 2021

Journal Articles

Tfr2 Genetic Deletion Makes Transfusion-Independent a Murine Model of Transfusion-Dependent β-Thalassemia

Simona Maria Di Modica, Violante Olivari, Emanuele Tanzi, Mariateresa Pettinato, Maria Rosa Lidonnici, Alessia Pagani, Francesca Tiboni, Giuliana Ferrari, Laura Silvestri, Stefano Rivella, Antonella Nai

Blood (2021) 138 (Supplement 1): 575.

https://doi.org/10.1182/blood-2021-148419

Published: 2021

Journal Articles

Dissecting the Mechanisms of Hepcidin and BMP-SMAD Pathway Regulation By FKBP12

Alessia Pagani, Mariateresa Pettinato, Alessandro Dulja, Silvia Colucci, Mariam Aghajan, Valeria Furiosi, Martina U. Muckenthaler, Shuling Guo, Antonella Nai, Laura Silvestri

Blood (2021) 138 (Supplement 1): 2008.

https://doi.org/10.1182/blood-2021-152172

Published: 2021

Journal Articles

The Immunophilin FKBP12 Inhibits Hepcidin By Modulating BMP Type I-Type II Receptors Interaction and Ligand Responsiveness

Alessandro Dulja, MSc, Alessia Pagani, PhD, Mariateresa Pettinato, Antonella Nai, PhD, Clara Camaschella, MD, Laura Silvestri, PhD

Blood (2019) 134 (Supplement_1): 430.

https://doi.org/10.1182/blood-2019-130058

Published: 2019

Journal Articles

Targeting the BMP Receptor Inhibitor FKBP12 to Upregulate Hepcidin in Wild-Type and Hemojuvelin-Hemochromatosis Models

Mariateresa Pettinato, Mariam Aghajan, PhD, Violante Olivari, MSc, Alessandro Dulja, MSc, Antonella Nai, PhD, Jessica Bordini, PhD, Alessandro Campanella, PhD, Alessia Pagani, PhD, Shuling Guo, PhD, Clara Camaschella, MD, Laura Silvestri, PhD

Blood (2019) 134 (Supplement_1): 955.

https://doi.org/10.1182/blood-2019-126496

Published: 2019

Journal Articles

Targeting Transferrin Receptor 2: A Novel "Erythropoiesis-Stimulating Approach" in a Model of Anemia of Chronic Kidney Disease

Violante Olivari, MSc, Maria Rosa Lidonnici, PhD, Mariateresa Pettinato, Laura Silvestri, PhD, Giuliana Ferrari, PhD, Clara Camaschella, MD, Antonella Nai, PhD

Blood (2019) 134 (Supplement_1): 956.

https://doi.org/10.1182/blood-2019-125783

Published: 2019

Journal Articles

Exploring the Mechanisms of Thalassemic Erythropoiesis Improvement Caused By Bone Marrow Tfr2 Deletion

Antonella Nai, PhD, Irene Artuso, MSc, Maria Rosa Lidonnici, PhD, Sandro Altamura, PhD, Giacomo Mandelli, PhD, Mariateresa Pettinato, MSc, Martina U. Muckenthaler, PhD, Laura Silvestri, PhD, Giuliana Ferrari, PhD, Clara Camaschella, MD

Blood (2018) 132 (Supplement 1): 3624.

https://doi.org/10.1182/blood-2018-99-115835

Published: 2018

Journal Articles

Novel Insights Into Systemic Iron Regulation

Laura Silvestri, PhD, Alessia Pagani, PhD, Antonella Nai, PhD, Clara Camaschella, MD

Blood (2018) 132 (Supplement 1): SCI-1.

https://doi.org/10.1182/blood-2018-99-109518

Published: 2018

Journal Articles

Inhibiting the Immunophilin FKBP12: A Potential Therapeutic Approach to Iron Overload/Low Hepcidin Disorders

Mariateresa Pettinato, MSc, Mariam Aghajan, Alessandro Dulja, Antonella Nai, PhD, Violante Olivari, Jessica Bordini, MSc, Alessandro Campanella, PhD, Alessia Pagani, PhD, Shuling Guo, Clara Camaschella, MD, Laura Silvestri, PhD

Blood (2018) 132 (Supplement 1): 2333.

https://doi.org/10.1182/blood-2018-99-118112

Published: 2018

Journal Articles

Transferrin receptor 2 is a potential novel therapeutic target for β-thalassemia: evidence from a murine model

Irene Artuso, Maria Rosa Lidonnici, Sandro Altamura, Giacomo Mandelli, Mariateresa Pettinato, Martina U. Muckenthaler, Laura Silvestri, Giuliana Ferrari, Clara Camaschella, Antonella Nai

Blood (2018) 132 (21): 2286–2297.

https://doi.org/10.1182/blood-2018-05-852277

Published: 2018

Includes: Supplemental data

Journal Articles

Impairment in the Mesenchymal Bone-Marrow Niche of Beta-Thalassemia Patients and Association with Prolonged Iron Exposure

Stefania Crippa, PhD, Valeria Rossella, Biologist, Laura Silvestri, PhD, Annamaria Aprile, PhD, Samantha Scaramuzza, Silvia Rivis, maria Antonietta Avanzini, Marco Zecca, MD, Sarah Marktel, MD, Fabio Ciceri, MD, Alessandro Aiuti, MD, Giuliana Ferrari, PhD, Maria Ester Bernardo, MD PhD

Blood (2017) 130 (Supplement 1): 948.

https://doi.org/10.1182/blood.V130.Suppl_1.948.948

Published: 2017

Journal Articles

NCOA4 Links Iron Bioavailability to DNA Metabolism

Giorgia Federico, PhD, Roberto Bellelli, PhD, Antonella Nai, PhD, Laura Silvestri, PhD, Clara Camaschella, MD, Achille Iolascon, MD PhD, Massimo Santoro, MD, Francesca Carlomagno, MD

Blood (2017) 130 (Supplement 1): 223.

https://doi.org/10.1182/blood.V130.Suppl_1.223.223

Published: 2017

Journal Articles

The Macrophage Nuclear Receptor Coactivator 4 Counteracts Iron-Deficiency Anemia

Antonella Nai, PhD, Maria Rosa Lidonnici, Irene Artuso, MSc, Giorgia Federico, PhD, Giacomo Mandelli, Giuliana Ferrari, PhD, Clara Camaschella, MD, Francesca Carlomagno, MD, Laura Silvestri, PhD

Blood (2017) 130 (Supplement 1): 224.

https://doi.org/10.1182/blood.V130.Suppl_1.224.224

Published: 2017

Journal Articles

Transient Reduction of Transferrin Saturation Contributes to Hepcidin Inhibition Independently of Erfe in Mice Treated with Erythropoietin

Irene Artuso, MSc, Antonella Nai, PhD, Mariateresa Pettinato, MSc, Alessia Pagani, PhD, Chloe Latour, Benjamin Billore, Maria Rosa Lidonnici, Giacomo Mandelli, Giuliana Ferrari, Clara Camaschella, MD, Leon C. Kautz, PhD, Laura Silvestri, PhD

Blood (2017) 130 (Supplement 1): 174.

https://doi.org/10.1182/blood.V130.Suppl_1.174.174

Published: 2017

Journal Articles

The immunophilin FKBP12 inhibits hepcidin expression by binding the BMP type I receptor ALK2 in hepatocytes

Silvia Colucci, Alessia Pagani, Mariateresa Pettinato, Irene Artuso, Antonella Nai, Clara Camaschella, Laura Silvestri

Blood (2017) 130 (19): 2111–2120.

https://doi.org/10.1182/blood-2017-04-780692

Published: 2017

Includes: Supplemental data

Journal Articles

A new form of IRIDA due to combined heterozygous mutations of TMPRSS6 and ACVR1A encoding the BMP receptor ALK2

Alessia Pagani, Silvia Colucci, Renata Bocciardi, Marta Bertamino, Carlo Dufour, Roberto Ravazzolo, Laura Silvestri, Clara Camaschella

Blood (2017) 129 (25): 3392–3395.

https://doi.org/10.1182/blood-2017-03-773481

Published: 2017

Includes: Supplemental data

Journal Articles

A Novel Crosstalk Between Iron Homeostasis and mTOR Mediated By the Immunophilin FKBP12

Laura Silvestri, PhD, Silvia Colucci, Alessia Pagani, PhD, Irene Artuso, BSc, Mariatesera Pettinato, BSc, Antonella Nai, PhD, Clara Camaschella, MD

Blood (2016) 128 (22): 261.

https://doi.org/10.1182/blood.V128.22.261.261

Published: 2016

NARROW

Ironing erythroid cells takes FLG1 and ERFE to tango

Iron is a modifier of the phenotypes of JAK2 -mutant myeloproliferative neoplasms

Bone Marrow Tfr2 Deletion Modulates Systemic Metabolism in β-Thalassemic Mice to Sustain Augmented Erythropoiesis

Rebalancing Iron Homeostasis and Erythropoiesis through Tfr2 Inhibition for Correction of Anemia in CKD

Tfr2 Genetic Deletion Makes Transfusion-Independent a Murine Model of Transfusion-Dependent β-Thalassemia

Dissecting the Mechanisms of Hepcidin and BMP-SMAD Pathway Regulation By FKBP12

The Immunophilin FKBP12 Inhibits Hepcidin By Modulating BMP Type I-Type II Receptors Interaction and Ligand Responsiveness

Targeting the BMP Receptor Inhibitor FKBP12 to Upregulate Hepcidin in Wild-Type and Hemojuvelin-Hemochromatosis Models

Targeting Transferrin Receptor 2: A Novel "Erythropoiesis-Stimulating Approach" in a Model of Anemia of Chronic Kidney Disease

Exploring the Mechanisms of Thalassemic Erythropoiesis Improvement Caused By Bone Marrow Tfr2 Deletion

Novel Insights Into Systemic Iron Regulation

Inhibiting the Immunophilin FKBP12: A Potential Therapeutic Approach to Iron Overload/Low Hepcidin Disorders

Transferrin receptor 2 is a potential novel therapeutic target for β-thalassemia: evidence from a murine model

Impairment in the Mesenchymal Bone-Marrow Niche of Beta-Thalassemia Patients and Association with Prolonged Iron Exposure

NCOA4 Links Iron Bioavailability to DNA Metabolism

The Macrophage Nuclear Receptor Coactivator 4 Counteracts Iron-Deficiency Anemia

Transient Reduction of Transferrin Saturation Contributes to Hepcidin Inhibition Independently of Erfe in Mice Treated with Erythropoietin

The immunophilin FKBP12 inhibits hepcidin expression by binding the BMP type I receptor ALK2 in hepatocytes

A new form of IRIDA due to combined heterozygous mutations of TMPRSS6 and ACVR1A encoding the BMP receptor ALK2

A Novel Crosstalk Between Iron Homeostasis and mTOR Mediated By the Immunophilin FKBP12

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American Society of Hematology

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American Society of Hematology

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