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Vania Manolova
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Journal Articles

Genetic iron overload aggravates and pharmacological iron restriction improves MDS pathophysiology in a preclinical study

Ada Antypiuk, Steven Vance, Richa Sharma, Sara T. Passos, Michela Asperti, Shobana Navaneethabalakrishnan, Franz Durrenberger, Vania Manolova, Francesca Vinchi, Prof.
Journal: Blood
Blood blood.2024026135.
https://doi.org/10.1182/blood.2024026135
Published: 2024
Includes: Supplemental data
Journal Articles

Combination Therapy with Luspatercept and the Ferroportin Inhibitor Vamifeport Is Superior to Either Drug Alone in Improving Anemia and Reducing Myeloid Skewing in MDS

Ada Antypiuk, Steven Vance, Franz Dürrenberger, Vania Manolova, Francesca Vinchi
Journal: Blood
Blood (2023) 142 (Supplement 1): 3836.
https://doi.org/10.1182/blood-2023-190095
Published: 2023
Journal Articles

Iron Restriction Alleviates β-Thalassemia By Stimulating ULK1-Mediated Autophagy of Free α-Globin

Alfonso G. Fernandez, Georgios E. Christakopoulos, Dudley E. Michael, Razan B. A. Sweileh, Rahul Telange, Heather Sheppard, Yu Yao, Jingjing Zhang, Vania Manolova, Elizabeta Nemeth, Tomas Ganz, Mitchell J. Weiss
Journal: Blood
Blood (2023) 142 (Supplement 1): 558.
https://doi.org/10.1182/blood-2023-185008
Published: 2023
Journal Articles

Iron is a modifier of the phenotypes of JAK2 -mutant myeloproliferative neoplasms

Jan Stetka, Marc Usart, Lucia Kubovcakova, Shivam Rai, Tata Nageswara Rao, Joshua Sutter, Hui Hao-Shen, Stefan Dirnhofer, Florian Geier, Michael S. Bader, Jakob R. Passweg, Vania Manolova, Franz Dürrenberger, Nouraiz Ahmed, Timm Schroeder, Tomas Ganz, Elizabeta Nemeth, Laura Silvestri, Antonella Nai, Clara Camaschella, Radek C. Skoda
Journal: Blood
Blood (2023) 141 (17): 2127–2140.
https://doi.org/10.1182/blood.2022017976
Published: 2023
Includes: Supplemental data
Journal Articles

Genetic Iron Overload Aggravates and Pharmacological Iron Restriction Improves MDS Pathophysiology in a Preclinical Mouse Model

S. Zebulon Vance, Ada Antypiuk, Richa Sharma, Franz Dürrenberger, Vania Manolova, Francesca Vinchi
Journal: Blood
Blood (2022) 140 (Supplement 1): 5341–5342.
https://doi.org/10.1182/blood-2022-170164
Published: 2022
Journal Articles

The oral ferroportin inhibitor vamifeport improves hemodynamics in a mouse model of sickle cell disease

Naja Nyffenegger, Rahima Zennadi, Natarajaswamy Kalleda, Anna Flace, Giada Ingoglia, Raphael M. Buzzi, Cédric Doucerain, Paul W. Buehler, Dominik J. Schaer, Franz Dürrenberger, Vania Manolova
Journal: Blood
Blood (2022) 140 (7): 769–781.
https://doi.org/10.1182/blood.2021014716
Published: 2022
Includes: Multimedia, Supplemental data