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Ada Antypiuk
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Journal Articles

Genetic iron overload aggravates and pharmacological iron restriction improves MDS pathophysiology in a preclinical study

Ada Antypiuk, Steven Vance, Richa Sharma, Sara T. Passos, Michela Asperti, Shobana Navaneethabalakrishnan, Franz Durrenberger, Vania Manolova, Francesca Vinchi, Prof.
Journal: Blood
Blood blood.2024026135.
https://doi.org/10.1182/blood.2024026135
Published: 2024
Includes: Supplemental data
Journal Articles

Myelodysplastic Syndromes Benefit from Iron-Restricted Bone Marrow Transplant in Preclinical Mouse Model

Ada Antypiuk, Alberto Martinez, Ute Schaeper, Uwe Platzbecker, Francesca Vinchi
Journal: Blood
Blood (2023) 142 (Supplement 1): 2462.
https://doi.org/10.1182/blood-2023-189794
Published: 2023
Journal Articles

Combination Therapy with Luspatercept and the Ferroportin Inhibitor Vamifeport Is Superior to Either Drug Alone in Improving Anemia and Reducing Myeloid Skewing in MDS

Ada Antypiuk, Steven Vance, Franz Dürrenberger, Vania Manolova, Francesca Vinchi
Journal: Blood
Blood (2023) 142 (Supplement 1): 3836.
https://doi.org/10.1182/blood-2023-190095
Published: 2023
Journal Articles

Macrophage metabolic rewiring improves heme-suppressed efferocytosis and tissue damage in sickle cell disease

Richa Sharma, Ada Antypiuk, S. Zebulon Vance, Deepa Manwani, Quentinn Pearce, James E. Cox, Xiuli An, Karina Yazdanbakhsh, Francesca Vinchi
Journal: Blood
Blood (2023) 141 (25): 3091–3108.
https://doi.org/10.1182/blood.2022018026
Published: 2023
Includes: Supplemental data
Journal Articles

Genetic Iron Overload Aggravates and Pharmacological Iron Restriction Improves MDS Pathophysiology in a Preclinical Mouse Model

S. Zebulon Vance, Ada Antypiuk, Richa Sharma, Franz Dürrenberger, Vania Manolova, Francesca Vinchi
Journal: Blood
Blood (2022) 140 (Supplement 1): 5341–5342.
https://doi.org/10.1182/blood-2022-170164
Published: 2022
Journal Articles

Differential Recovery of Macrophage Iron Deficiency By Oral Iron Formulations Determines Cell Inflammatory Response in Conditions of Iron Deficiency Anemia

Ada Antypiuk, Richa Sharma, Elisa Brilli, Germano Tarantino, Francesca Vinchi
Journal: Blood
Blood (2022) 140 (Supplement 1): 5335–5336.
https://doi.org/10.1182/blood-2022-165292
Published: 2022
Journal Articles

Heme and Iron Aggravate Tissue Damage in Sickle Cell Disease By Driving Macrophage Functional Reprogramming through the Coordinated Suppression of Efferocytosis and Mitochondrial Metabolism

Richa Sharma, S. Zebulon Vance, Ada Antypiuk, Deepa Manwani, Quentinn Pearce, James E. Cox, Xiuli An, Karina Yazdanbakhsh, Francesca Vinchi
Journal: Blood
Blood (2022) 140 (Supplement 1): 2456–2457.
https://doi.org/10.1182/blood-2022-165364
Published: 2022