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Journal Articles

Macrophage metabolic rewiring improves heme-suppressed efferocytosis and tissue damage in sickle cell disease

Richa Sharma, Ada Antypiuk, S. Zebulon Vance, Deepa Manwani, Quentinn Pearce, James E. Cox, Xiuli An, Karina Yazdanbakhsh, Francesca Vinchi
Journal: Blood
Blood (2023) 141 (25): 3091–3108.
https://doi.org/10.1182/blood.2022018026
Published: 2023
Includes: Supplemental data
Journal Articles

Heme and Iron Aggravate Tissue Damage in Sickle Cell Disease By Driving Macrophage Functional Reprogramming through the Coordinated Suppression of Efferocytosis and Mitochondrial Metabolism

Richa Sharma, S. Zebulon Vance, Ada Antypiuk, Deepa Manwani, Quentinn Pearce, James E. Cox, Xiuli An, Karina Yazdanbakhsh, Francesca Vinchi
Journal: Blood
Blood (2022) 140 (Supplement 1): 2456–2457.
https://doi.org/10.1182/blood-2022-165364
Published: 2022