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Dominik J. Schaer
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Journal Articles

Hemolysis, free hemoglobin toxicity, and scavenger protein therapeutics

Florence Vallelian, Paul W. Buehler, Dominik J. Schaer
Journal: Blood
Blood (2022) 140 (17): 1837–1844.
https://doi.org/10.1182/blood.2022015596
Published: 2022
Journal Articles

The oral ferroportin inhibitor vamifeport improves hemodynamics in a mouse model of sickle cell disease

Naja Nyffenegger, Rahima Zennadi, Natarajaswamy Kalleda, Anna Flace, Giada Ingoglia, Raphael M. Buzzi, Cédric Doucerain, Paul W. Buehler, Dominik J. Schaer, Franz Dürrenberger, Vania Manolova
Journal: Blood
Blood (2022) 140 (7): 769–781.
https://doi.org/10.1182/blood.2021014716
Published: 2022
Includes: Multimedia, Supplemental data
Journal Articles

Hemoglobin concentration of young men at residential altitudes between 200 and 2000 m mirrors Switzerland's topography

Clinical Trials & Observations
Kaspar Staub, Martin Haeusler, Nicole Bender, Irina Morozova, Patrick Eppenberger, Radoslaw Panczak, Marcel Zwahlen, Dominik J. Schaer, Marco Maggiorini, Silvia Ulrich, Norina N. Gassmann, Martina U. Muckenthaler, Frank Rühli, Max Gassmann
Journal: Blood
Blood (2020) 135 (13): 1066–1069.
https://doi.org/10.1182/blood.2019004135
Published: 2020
Includes: Supplemental data
Journal Articles

Hemolysis and free hemoglobin revisited: exploring hemoglobin and hemin scavengers as a novel class of therapeutic proteins

Dominik J. Schaer, Paul W. Buehler, Abdu I. Alayash, John D. Belcher, Gregory M. Vercellotti
Journal: Blood
Blood (2013) 121 (8): 1276–1284.
https://doi.org/10.1182/blood-2012-11-451229
Published: 2013
Journal Articles

Glucocorticoid treatment skews human monocyte differentiation into a hemoglobin-clearance phenotype with enhanced heme-iron recycling and antioxidant capacity

Florence Vallelian, Christian A. Schaer, Theresa Kaempfer, Peter Gehrig, Elena Duerst, Gabriele Schoedon, Dominik J. Schaer
Journal: Blood
Blood (2010) 116 (24): 5347–5356.
https://doi.org/10.1182/blood-2010-04-277319
Published: 2010
Includes: Supplemental data
Journal Articles

Haptoglobin preserves the CD163 hemoglobin scavenger pathway by shielding hemoglobin from peroxidative modification

Paul W. Buehler, Bindu Abraham, Florence Vallelian, Charlotte Linnemayr, Claudia P. Pereira, John F. Cipollo, Yiping Jia, Malgorzata Mikolajczyk, Felicitas S. Boretti, Gabriele Schoedon, Abdu I. Alayash, Dominik J. Schaer
Journal: Blood
Blood (2009) 113 (11): 2578–2586.
https://doi.org/10.1182/blood-2008-08-174466
Published: 2009
Includes: Supplemental data
Journal Articles

CD163 is the macrophage scavenger receptor for native and chemically modified hemoglobins in the absence of haptoglobin

Dominik J. Schaer, Christian A. Schaer, Paul W. Buehler, Robert A. Boykins, Gabriele Schoedon, Abdu I. Alayash, Andreas Schaffner
Journal: Blood
Blood (2006) 107 (1): 373–380.
https://doi.org/10.1182/blood-2005-03-1014
Published: 2006
Includes: Supplemental data
Journal Articles

Expression of the hemoglobin scavenger receptor (CD163/HbSR) as immunophenotypic marker of monocytic lineage in acute myeloid leukemia

Roland B. Walter, Esther B. Bächli, Dominik J. Schaer, Regula Rüegg, Gabriele Schoedon
Journal: Blood
Blood (2003) 101 (9): 3755.
https://doi.org/10.1182/blood-2002-11-3414
Published: 2003