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Tae-Hoon Shin
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Journal Articles

A RUNX1 -FPDMM rhesus macaque model reproduces the human phenotype and predicts challenges to curative gene therapies

Brief Report
Byung-Chul Lee, Yifan Zhou, Erica Bresciani, Neval Ozkaya, Alina Dulau-Florea, Blake Carrington, Tae-Hoon Shin, Valentina Baena, Zulfeqhar A. Syed, So Gun Hong, Tao Zhen, Katherine R. Calvo, Paul Liu, Cynthia E. Dunbar
Journal: Blood
Blood (2023) 141 (3): 231–237.
https://doi.org/10.1182/blood.2022018193
Published: 2023
Includes: Supplemental data
Journal Articles

A macaque clonal hematopoiesis model demonstrates expansion of TET2-disrupted clones and utility for testing interventions

Tae-Hoon Shin, Yifan Zhou, Shirley Chen, Stefan Cordes, Max Z. Grice, Xing Fan, Byung-Chul Lee, Aisha A. Aljanahi, So Gun Hong, Kelli L. Vaughan, Julie A. Mattison, Steven G. Kohama, Margarete A. Fabre, Naoya Uchida, Selami Demirci, Marcus A. F. Corat, Jean-Yves Métais, Katherine R. Calvo, Manuel Buscarlet, Hannah Natanson, Kathy L. McGraw, Alan F. List, Lambert Busque, John F. Tisdale, George S. Vassiliou, Kyung-Rok Yu, Cynthia E. Dunbar
Journal: Blood
Blood (2022) 140 (16): 1774–1789.
https://doi.org/10.1182/blood.2021014875
Published: 2022
Includes: Supplemental data
Journal Articles

Clonal hematopoiesis is not significantly associated with COVID-19 disease severity

Clinical Trials & Observations
Yifan Zhou, Ruba Shalhoub, Stephanie N. Rogers, Shiqin Yu, Muxin Gu, Margarete A. Fabre, Pedro M. Quiros, Tae-Hoon Shin, Arch Diangson, Wenhan Deng, Shubha Anand, Wenhua Lu, Matthew Cullen, Anna L. Godfrey, Jacobus Preller, Jerome Hadjadj, Emmanuelle Jouanguy, Aurélie Cobat, Laurent Abel, Frederic Rieux-Laucat, Benjamin Terrier, Alain Fischer, Lara Novik, Ingelise J. Gordon, Larisa Strom, Martin R. Gaudinski, Andrea Lisco, Irini Sereti, Thomas J. Gniadek, Andrea Biondi, Paolo Bonfanti, Luisa Imberti, Clifton L. Dalgard, Yu Zhang, Kerry Dobbs, Helen C. Su, Luigi D. Notarangelo, Colin O. Wu, Peter J. M. Openshaw, Malcolm G. Semple, Ziad Mallat, Kenneth Baillie, Cynthia E. Dunbar, George S. Vassiliou
Journal: Blood
Blood (2022) 140 (14): 1650–1655.
https://doi.org/10.1182/blood.2022015721
Published: 2022
Includes: Supplemental data
Journal Articles

CRISPR/Cas9 PIG -A gene editing in nonhuman primate model demonstrates no intrinsic clonal expansion of PNH HSPCs

Tae-Hoon Shin, Eun Jung Baek, Marcus A. F. Corat, Shirley Chen, Jean-Yves Metais, Aisha A. AlJanahi, Yifan Zhou, Robert E. Donahue, Kyung-Rok Yu, Cynthia E. Dunbar
Journal: Blood
Blood (2019) 133 (23): 2542–2545.
https://doi.org/10.1182/blood.2019000800
Published: 2019
Includes: Supplemental data
Journal Articles

The impact of aging on primate hematopoiesis as interrogated by clonal tracking

Kyung-Rok Yu, Diego A. Espinoza, Chuanfeng Wu, Lauren Truitt, Tae-Hoon Shin, Shirley Chen, Xing Fan, Idalia M. Yabe, Sandhya Panch, So Gun Hong, Samson Koelle, Rong Lu, Aylin Bonifacino, Allen Krouse, Mark Metzger, Robert E. Donahue, Cynthia E. Dunbar
Journal: Blood
Blood (2018) 131 (11): 1195–1205.
https://doi.org/10.1182/blood-2017-08-802033
Published: 2018
Includes: Supplemental data