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Journal Articles

Defining evolutionary trajectories in myelodysplastic syndromes and integrating them into prognostic models to improve risk stratification: The progevo machine learning approach

Blood (2025) 146 (Supplement 1): 3847.

https://doi.org/10.1182/blood-2025-3847

Published: 2025

Journal Articles

CMML2AML: Machine-learning discovery of co-mutations predictive of blast transformation in chronic myelomonocytic leukemia

Blood (2025) 146 (Supplement 1): 3844.

https://doi.org/10.1182/blood-2025-3844

Published: 2025

Journal Articles

Clonal evolution and risk assessment in myelodysplastic syndromes (MDS): A prospective Study of dynamic IPSS-m validation and evolutionary trajectory modeling by the italian MDS foundation (FISIM)

Luca Lanino, Matteo Zampini, Ivan Civettini, Daniele Ramazzotti, Alessia Campagna, Elena Riva, Denise Ventura, Nicole Pinocchio, Pasquale Niscola, Marco Gabriele Raddi, Angela Consagra, Federica Pilo, Antonella Poloni, Mariarita Sciumè, Andrea Patriarca, Stefania Paolini, Carlo Finelli, Andrea Castelli, Pellegrino Musto, Anna Calvisi, Grazia Sanpaolo, Monia Marchetti, Elisa Diral, Germana Beltrami, Carmen Fava, Claudio Fozza, Chiara Frairia, Carmine Selleri, Daniela Barraco, Domenico Pastore, Rosanna Ciancia, Elena Crisa, Enrico Balleari, Susanna Gallo, Vincenzo Pavone, Esther Natalie Oliva, Giulia Maggioni, Ferdinando Frigeri, Gabriele Todisco, Antonio Russo, Alessandro Buizza, Ivan Ferrari, Giulia Figini, Alessandra Crespi, Elisa Calvetti, Chiara Milanesi, Nicla Manes, Francesco Pesce, Saverio D'Amico, Gianluca Asti, Elisabetta Sauta, Guido Sanguinetti, Gastone Castellani, Marilena Bicchieri, Ilaria Naldi, Francesca Ficara, Valeria Santini, Marta Ubezio, Matteo Della Porta

Blood (2025) 146 (Supplement 1): 3842.

https://doi.org/10.1182/blood-2025-3842

Published: 2025

Journal Articles

Immune-based risk score derived from bulk and single-cell transcriptomics enhances prognostic stratification in MDS

Blood (2025) 146 (Supplement 1): 115.

https://doi.org/10.1182/blood-2025-115

Published: 2025

Journal Articles

Validation of blast and blast-mol risk models in chronic myelomonocytic leukemia: Mayo-humanitas collaborative project involving 1,101 patients

Saubia Fathima, Muhammad Yousuf, Priyansh Faldu, Ali Alsugair, Clifford Csizmar, Merry Nakhleh, Abhishek Mangaonkar, Animesh Pardanani, Luca Lanino, Alessia Campagna, Giulia Maggioni, Kaaren Reichard, Rong He, Naseema Gangat, Mrinal Patnaik, Matteo Della Porta, Ayalew Tefferi

Blood (2025) 146 (Supplement 1): 2077.

https://doi.org/10.1182/blood-2025-2077

Published: 2025

Journal Articles

Safe: A multimodal, scalable and clinically-oriented comprehensive framework for synthetic data validation in hematology

Blood (2025) 146 (Supplement 1): 396.

https://doi.org/10.1182/blood-2025-396

Published: 2025

Journal Articles

Single-cell multi-omics profiling reveals distinct patterns of clonal expansion and microenvironmental shifts associated with disease evolution in patients with Myelodysplastic Syndromes

Matteo Zampini, Elena Riva, Nicolas Sompairac, Giulia Maggioni, Rita Antunes Dos Reis, Rosa Andres Ejarque, Laura Crisafulli, Nicolas Derus, Martina Tarozzi, Claudia Sala, Pamela Acha, Emili Cid Roldós, Elisabetta Sauta, Luca Lanino, Alessia Campagna, Gabriele Todisco, Marta Ubezio, Antonio Russo, Francesco Pesce, Mattia Delleani, Gianluca Asti, Denise Ventura, Cristina Astrid Tentori, Alessandro Buizza, Ivan Ferrari, Matteo Brindisi, Nicole Pinocchio, Elisa Calvetti, Nicla Manes, Chiara Milanesi, Mara Memoli, Federico Caretti, Rongrong Xie, Lorea Chaparro, Caterina Mata, Armando Santoro, Valeria Santini, Amer Zeidan, Rami Komrokji, Paola Guglielmelli, Alessandro Vannucchi, Guillermo Garcia-Manero, Simona Colla, Saverio D'Amico, Guido Sanguinetti, Gastone Castellani, Francesc Sole, Shahram Kordasti, Francesca Ficara, Matteo Della Porta

Blood (2025) 146 (Supplement 1): 3830.

https://doi.org/10.1182/blood-2025-3830

Published: 2025

Journal Articles

AI-based, secure and privacy-preserving synthetic data generation platform in transfusion-dependent β-thalassemia applied to the Webthal® dataset

Blood (2025) 146 (Supplement 1): 4351.

https://doi.org/10.1182/blood-2025-4351

Published: 2025

Journal Articles

Development and validation of synthetic data generation over a federated learning computing framework to accelerate innovation and boost personalized medicine in hematological diseases

Blood (2025) 146 (Supplement 1): 4350.

https://doi.org/10.1182/blood-2025-4350

Published: 2025

Journal Articles

Clinical and technological validation of locally-installed, privacy-compliant, and hematology-tailored ambient AI platform for clinical report transcription assistance and clinical trial patient management

Blood (2025) 146 (Supplement 1): 6129.

https://doi.org/10.1182/blood-2025-6129

Published: 2025

Journal Articles

IPSS-M risk and specific sex-associated somatic mutations predict response to ESA therapy in LR-MDS: building a new score

Blood (2025) 146 (14): 1693–1706.

https://doi.org/10.1182/blood.2024027540

Published: 2025

Includes: Supplemental data

Journal Articles

Generation of Multimodal Longitudinal Synthetic Data By Artificial Intelligence to Improve Personalized Medicine in Hematology

Blood (2024) 144 (Supplement 1): 4981.

https://doi.org/10.1182/blood-2024-209541

Published: 2024

Journal Articles

Artificial Intelligence-Powered Digital Pathology to Improve Diagnosis and Personalized Prognostic Assessment in Patient with Myeloid Neoplasms

Blood (2024) 144 (Supplement 1): 3598.

https://doi.org/10.1182/blood-2024-206248

Published: 2024

Journal Articles

Clonal Hematopoiesis and the Risk of Dementia: The Monzino 80-Plus Population-Based Study

Alessandro Buizza, Alessia Antonella Galbussera, Francesco Pesce, Matteo Zampini, Luca Lanino, Gabriele Todisco, Alessia Campagna, Giulia Maggioni, Marta Ubezio, Saverio D'Amico, Elisabetta Sauta, Antonio Russo, Daniele Dall'Olio, Francesca Ficara, Stefano Polizzi, Gastone Castellani, Mauro Tettamanti, Ugo Lucca, Matteo Giovanni Della Porta

Blood (2024) 144 (Supplement 1): 4052.

https://doi.org/10.1182/blood-2024-200995

Published: 2024

Journal Articles

Landscape of Immune Cell States and Ecosystems in Patients with Myelodysplastic Syndrome to Refine Prognostic Assessment and Predict Treatment Response. a Study By i4MDS Consortium

Blood (2024) 144 (Supplement 1): 665.

https://doi.org/10.1182/blood-2024-200184

Published: 2024

Journal Articles

Enhancing Personalized Prognostic Assessment of Myelodysplastic Syndromes through a Multimodal and Explainable Deep Data Fusion Approach (MAGAERA)

Blood (2024) 144 (Supplement 1): 105.

https://doi.org/10.1182/blood-2024-205413

Published: 2024

Journal Articles

Clinical Relevance of the Integrative Analysis of Gut Microbiome and Metabolomics in Myeloid Neoplasms: Correlations with Genomic Profiles, Treatment Response/Complications and Clinical Outcome

Blood (2024) 144 (Supplement 1): 104.

https://doi.org/10.1182/blood-2024-204635

Published: 2024

Journal Articles

A Molecular-Based Ecosystem to Improve Personalized Medicine in Patients with Chronic Myelomonocytic Leukemia (CMML)

Luca Lanino, Anthony M. Hunter, Nico Gagelmann, Marie Robin, Claudia Sala, Daniele Dall'Olio, Carmelo Gurnari, Lorenzo Dall'Olio, Yu-Hung Wang, Lisa Pleyer, Blanca Xicoy, Guillermo Montalban-Bravo, Lee-Yung Shih, Tamanna Haque, Omar Abdel-Wahab, Klaus Geissler, Alex Bataller, Alexandre Bazinet, Manja Meggendorfer, Ilaria Carola Casetti, Elisabetta Sauta, Erica Travaglino, Laura Palomo, Lurdes Zamora, David Quintela, Andres Jerez, Elena Cornejo, Paloma Garcia Martin, Marina Díaz-Beyá, Alejandro Avendaño Pita, Veronica Roldan, Dolly Viviana Fiallo Suarez, Estefania Cerezo Velasco, Marisa Calabuig, Esperanza Such, Guillermo Sanz, Anne Sophie Kubasch, Cristina Castilla-Llorente, Claude-Éric Bulabois, Laetitia Souchet, Hussein Awada, Massimo Bernardi, Patrizia Chiusolo, Antonio Curti, Luisa Giaccone, Francesco Onida, Lorenza Maria Borin, Francesco Passamonti, Elisa Diral, Vladan Vucinic, Gregorio Maria Bergonzi, Maria Teresa Voso, Hsin-An Hou, Wen-Chien Chou, Chi-Yuan Yao, Chien-Chin Lin, Hwei-Fang Tien, Alessia Campagna, Marta Ubezio, Antonio Russo, Gabriele Todisco, Giulia Maggioni, Cristina Astrid Tentori, Alessandro Buizza, Gianluca Asti, Matteo Zampini, Elena Riva, Mattia Delleani, Angela Consagra, Francesca Ficara, Armando Santoro, Luciana Carota, Tiziana Sanavia, Cesare Rollo, Ahmad Kiwan, Jennifer VanOudenhove, Piero Fariselli, Najla H. Al Ali, David Sallman, Wolfgang Kern, Guillermo Garcia-Manero, Swapna Thota, Elizabeth A. Griffiths, Matilde Yung Follo, Carlo Finelli, Uwe Platzbecker, Francesc Sole, Maria Diez-Campelo, Jaroslaw Maciejewski, Rafael Bejar, Felicitas R. Thol, Nicolaus Kröger, Pierre Fenaux, Raphael Itzykson, Timothy Aaron Graubert, Michaela Fontenay, Amer M. Zeidan, Rami S. Komrokji, Valeria Santini, Torsten Haferlach, Ulrich Germing, Saverio D'Amico, Gastone Castellani, Mrinal M. Patnaik, Eric Solary, Eric Padron, Matteo Giovanni Della Porta

Blood (2024) 144 (Supplement 1): 1003.

https://doi.org/10.1182/blood-2024-200104

Published: 2024

Journal Articles

Performance of the Molecular International Prognostic Scoring System (IPSS-M) in Myelodysplastic Syndromes Treated with Hypomethylating Agent-Based Therapy: A Multicenter Analysis

Blood (2024) 144 (Supplement 1): 4584.

https://doi.org/10.1182/blood-2024-210646

Published: 2024

Journal Articles

Single-Cell Multi-Omics Reveals Anticipated Erythroid Differentiation and Transcriptional Regulation in Differentiation Trajectories of SF3B1 - JAK2/MPL Mutated Cells in MDS/MPN-RS-T

Blood (2024) 144 (Supplement 1): 3194.

https://doi.org/10.1182/blood-2024-201085

Published: 2024

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Defining evolutionary trajectories in myelodysplastic syndromes and integrating them into prognostic models to improve risk stratification: The progevo machine learning approach

CMML2AML: Machine-learning discovery of co-mutations predictive of blast transformation in chronic myelomonocytic leukemia

Clonal evolution and risk assessment in myelodysplastic syndromes (MDS): A prospective Study of dynamic IPSS-m validation and evolutionary trajectory modeling by the italian MDS foundation (FISIM)

Immune-based risk score derived from bulk and single-cell transcriptomics enhances prognostic stratification in MDS

Validation of blast and blast-mol risk models in chronic myelomonocytic leukemia: Mayo-humanitas collaborative project involving 1,101 patients

Safe: A multimodal, scalable and clinically-oriented comprehensive framework for synthetic data validation in hematology

Single-cell multi-omics profiling reveals distinct patterns of clonal expansion and microenvironmental shifts associated with disease evolution in patients with Myelodysplastic Syndromes

AI-based, secure and privacy-preserving synthetic data generation platform in transfusion-dependent β-thalassemia applied to the Webthal® dataset

Development and validation of synthetic data generation over a federated learning computing framework to accelerate innovation and boost personalized medicine in hematological diseases

Clinical and technological validation of locally-installed, privacy-compliant, and hematology-tailored ambient AI platform for clinical report transcription assistance and clinical trial patient management

IPSS-M risk and specific sex-associated somatic mutations predict response to ESA therapy in LR-MDS: building a new score

Generation of Multimodal Longitudinal Synthetic Data By Artificial Intelligence to Improve Personalized Medicine in Hematology

Artificial Intelligence-Powered Digital Pathology to Improve Diagnosis and Personalized Prognostic Assessment in Patient with Myeloid Neoplasms

Clonal Hematopoiesis and the Risk of Dementia: The Monzino 80-Plus Population-Based Study

Landscape of Immune Cell States and Ecosystems in Patients with Myelodysplastic Syndrome to Refine Prognostic Assessment and Predict Treatment Response. a Study By i4MDS Consortium

Enhancing Personalized Prognostic Assessment of Myelodysplastic Syndromes through a Multimodal and Explainable Deep Data Fusion Approach (MAGAERA)

Clinical Relevance of the Integrative Analysis of Gut Microbiome and Metabolomics in Myeloid Neoplasms: Correlations with Genomic Profiles, Treatment Response/Complications and Clinical Outcome

A Molecular-Based Ecosystem to Improve Personalized Medicine in Patients with Chronic Myelomonocytic Leukemia (CMML)

Performance of the Molecular International Prognostic Scoring System (IPSS-M) in Myelodysplastic Syndromes Treated with Hypomethylating Agent-Based Therapy: A Multicenter Analysis

Single-Cell Multi-Omics Reveals Anticipated Erythroid Differentiation and Transcriptional Regulation in Differentiation Trajectories of SF3B1 - JAK2/MPL Mutated Cells in MDS/MPN-RS-T

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