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Journal Articles

2025 Update on MRD in Acute Myeloid Leukemia: A Consensus Document from the ELN-DAVID MRD Working Party

Blood blood.2025031480.

https://doi.org/10.1182/blood.2025031480

Published: 2025

Includes: Supplemental data

Journal Articles

Proteogenomic analysis of NPM1-mutated AML reveals clinical heterogeneity related to differentiation states and mitochondrial metabolism

Sebastian Wolf, Josefine Jakob, Björn Häupl, Annika Meid, Daniela Späth, Felicitas R Thol, Hubert Serve, Konstanze Döhner, Hartmut Döhner, Thomas Oellerich

Blood (2025) 146 (Supplement 1): 660.

https://doi.org/10.1182/blood-2025-660

Published: 2025

Journal Articles

Allogeneic CAR-T therapy AVC-201 in AML positive for CD123

Blood (2025) 146 (Supplement 1): 3426.

https://doi.org/10.1182/blood-2025-3426

Published: 2025

Journal Articles

Establishing contemporary benchmarks for Acute Myeloid Leukemia outcomes and measurable residual disease: Real-world data utilization from the ELN-david MRD international working group

Blood (2025) 146 (Supplement 1): 5183.

https://doi.org/10.1182/blood-2025-5183

Published: 2025

Journal Articles

Clinical characteristics and comutational landscape of CSF3R mutations in acute myeloid leukemia

Lara Wiechers, Rabea Mecklenbrauck, Razif Gabdoulline, Henri C. Hupe, Piroska Poll, Rabia Shahswar, Franziska Westendorf, Walter Fiedler, Arnold Ganser, Florian Heidel, Michael Heuser, Felicitas R Thol

Blood (2025) 146 (Supplement 1): 1718.

https://doi.org/10.1182/blood-2025-1718

Published: 2025

Journal Articles

Monitoring of CNS involvement in AML using ultrahigh-sensitivity next-generation sequencing of cell-free DNA

Blood (2025) 146 (Supplement 1): 3515.

https://doi.org/10.1182/blood-2025-3515

Published: 2025

Journal Articles

Umbilical cord blood CD34+ hematopoietic stem cell-derived natural killer cells in Acute Myeloid Leukemia – a phase I clinical study

Blood (2025) 146 (Supplement 1): 1640.

https://doi.org/10.1182/blood-2025-1640

Published: 2025

Journal Articles

Adding eltrombopag to immunosuppressive treatment with cyclosporine as front-line therapy for moderate aplastic anemia improves trilineage hematologic response: One-year analysis of the randomised, placebo-controlled, double-blind Phase III trial eltrombopag for moderate aplastic anemia (EMAA Trial)

Britta Hoechsmann, Philippe Schafhausen, Fabian Beier, Michael Heuser, Joerg Westermann, Beatrice Drexler, Alexander Röth, Mathias Hänel, Flore Sicre-de-Fontbrune, Astrid Marx-Hofmann, Antonia Beitzen-Heineke, Jens Panse, Felicitas R Thol, Sixten Koerper, Tim H. Brummendorf, Hubert Schrezenmeier

Blood (2025) 146 (Supplement 1): 980.

https://doi.org/10.1182/blood-2025-980

Published: 2025

Journal Articles

CPX-351 in Down syndrome-associated Myeloid Leukemia: Results and Prognostic Factors from the Phase 3 ML-DS 2018 Trial

Blood blood.2025030775.

https://doi.org/10.1182/blood.2025030775

Published: 2025

Includes: Supplemental data

Journal Articles

Intra-Tumor Heterogeneity in Core-Binding Factor Acute Myeloid Leukemia

Raphael Hablesreiter, Paulina Strzelecka, Natalia Estrada, Klara Kopp, Anna Dolnik, Marlon Tilgner, Coral Fustero, Felicitas R Thol, Florian H. Heidel, Michael Heuser, Lars Bullinger, Friederike Christen, Frederik Damm

Blood (2024) 144 (Supplement 1): 2956.

https://doi.org/10.1182/blood-2024-202342

Published: 2024

Journal Articles

Prognostic Role of NGS-Based MRD Assessment in FLT3 -TKD Mutated Patients with Acute Myeloid Leukemia

Isabell Arnhardt, Christian M. Vonk, Xavier Cheng-Hong Tsai, Felicitas R. Thol, Wen-Chien Chou, Hsin-An Hou, Razif Gabdoulline, Florian H. Heidel, Hwei-Fang Tien, Michael Heuser, Peter J. M. Valk

Blood (2024) 144 (Supplement 1): 2951.

https://doi.org/10.1182/blood-2024-207981

Published: 2024

Journal Articles

Prognostic Impact of Subclinical FLT3 -ITD Microclones in Patients with Acute Myeloid Leukemia

Paul Olson, Razif Gabdoulline, Rabia Shahswar, Arnold Kloos, Letizia Venturini, Isabell Arnhardt, Henri C. Hupe, Victoria Panagiota, Michael Stadler, Matthias Eder, Gernot Beutel, Elke Dammann, Piroska Poll, Anke Bergmann, Nataliya DiDonato, Florian H. Heidel, Felicitas R. Thol, Michael Heuser

Blood (2024) 144 (Supplement 1): 847.

https://doi.org/10.1182/blood-2024-207703

Published: 2024

Journal Articles

The Prognostic Impact of Myelodysplasia-Related Gene Mutations in Acute Myeloid Leukemia with FLT3 -ITD Mutations

Blood (2024) 144 (Supplement 1): 844.

https://doi.org/10.1182/blood-2024-202362

Published: 2024

Journal Articles

A Molecular-Based Ecosystem to Improve Personalized Medicine in Patients with Chronic Myelomonocytic Leukemia (CMML)

Luca Lanino, Anthony M. Hunter, Nico Gagelmann, Marie Robin, Claudia Sala, Daniele Dall'Olio, Carmelo Gurnari, Lorenzo Dall'Olio, Yu-Hung Wang, Lisa Pleyer, Blanca Xicoy, Guillermo Montalban-Bravo, Lee-Yung Shih, Tamanna Haque, Omar Abdel-Wahab, Klaus Geissler, Alex Bataller, Alexandre Bazinet, Manja Meggendorfer, Ilaria Carola Casetti, Elisabetta Sauta, Erica Travaglino, Laura Palomo, Lurdes Zamora, David Quintela, Andres Jerez, Elena Cornejo, Paloma Garcia Martin, Marina Díaz-Beyá, Alejandro Avendaño Pita, Veronica Roldan, Dolly Viviana Fiallo Suarez, Estefania Cerezo Velasco, Marisa Calabuig, Esperanza Such, Guillermo Sanz, Anne Sophie Kubasch, Cristina Castilla-Llorente, Claude-Éric Bulabois, Laetitia Souchet, Hussein Awada, Massimo Bernardi, Patrizia Chiusolo, Antonio Curti, Luisa Giaccone, Francesco Onida, Lorenza Maria Borin, Francesco Passamonti, Elisa Diral, Vladan Vucinic, Gregorio Maria Bergonzi, Maria Teresa Voso, Hsin-An Hou, Wen-Chien Chou, Chi-Yuan Yao, Chien-Chin Lin, Hwei-Fang Tien, Alessia Campagna, Marta Ubezio, Antonio Russo, Gabriele Todisco, Giulia Maggioni, Cristina Astrid Tentori, Alessandro Buizza, Gianluca Asti, Matteo Zampini, Elena Riva, Mattia Delleani, Angela Consagra, Francesca Ficara, Armando Santoro, Luciana Carota, Tiziana Sanavia, Cesare Rollo, Ahmad Kiwan, Jennifer VanOudenhove, Piero Fariselli, Najla H. Al Ali, David Sallman, Wolfgang Kern, Guillermo Garcia-Manero, Swapna Thota, Elizabeth A. Griffiths, Matilde Yung Follo, Carlo Finelli, Uwe Platzbecker, Francesc Sole, Maria Diez-Campelo, Jaroslaw Maciejewski, Rafael Bejar, Felicitas R. Thol, Nicolaus Kröger, Pierre Fenaux, Raphael Itzykson, Timothy Aaron Graubert, Michaela Fontenay, Amer M. Zeidan, Rami S. Komrokji, Valeria Santini, Torsten Haferlach, Ulrich Germing, Saverio D'Amico, Gastone Castellani, Mrinal M. Patnaik, Eric Solary, Eric Padron, Matteo Giovanni Della Porta

Blood (2024) 144 (Supplement 1): 1003.

https://doi.org/10.1182/blood-2024-200104

Published: 2024

Journal Articles

CAR-T Cell Therapy for Acquired Hemophilia A

Blood (2024) 144 (Supplement 1): 5503.

https://doi.org/10.1182/blood-2024-202970

Published: 2024

Journal Articles

A Phase 1, Open-Label, Dose Escalation and Dose Expansion Study of Cln-049 for the Treatment of Acute Myeloid Leukemia Patients with Measurable Residual Disease

Blood (2024) 144 (Supplement 1): 2883.1.

https://doi.org/10.1182/blood-2024-201478

Published: 2024

Journal Articles

Reliable Assessment of Iron Deficiency in Patients with Myeloproliferative Neoplasms through Fluorescence Spectroscopy-Based Measurement of Zinc Protoporphyrin (ZPP)

Kirsi Manz, Myriam Kobrosly, Carl C Crodel, Haifa Kathrin Al-Ali, Susanne Isfort, Gernot Beutel, Victoria Panagiota, Felicitas R. Thol, Stefanie Jilg, Thomas Stauch, Wolfgang Hoffmann, Henry Völzke, William H Krüger, Andreas Hochhaus, Francesca Palandri, Tina M Schnoeder, Christian Homann, Florian H. Heidel

Blood (2024) 144 (Supplement 1): 1090.

https://doi.org/10.1182/blood-2024-205036

Published: 2024

Journal Articles

The Differential Impact of Secondary-Type Mutations in a Multinational Cohort of 5311 Intensively Treated Acute Myeloid Leukemia Patients

Jan-Niklas Eckardt, Marius Bill, Konstanze Döhner, Christian Rausch, Klaus H Metzeler, Karsten Spiekermann, Sebastian Stasik, Tim Sauer, Sebastian Scholl, Andreas Hochhaus, Martina Crysandt, Tim H. H. Brummendorf, Utz Krug, Bernhard Wörmann, Hermann Einsele, Wolfgang Hiddemann, Dennis Görlich, Maria Cristina Sauerland, Björn Steffen, Andreas Neubauer, Andreas Burchert, Kerstin Schaefer-Eckart, Wolfgang E. Berdel, Christoph Schliemann, Stefan W. Krause, Mathias Hänel, Maher Hanoun, Martin Kaufmann, Lars Fransecky, Jan Braess, Johannes Schetelig, Jan Moritz Middeke, Lars Bullinger, Michael Heuser, Felicitas R Thol, Hubert Serve, Claudia D Baldus, Uwe Platzbecker, Carsten Mueller-Tidow, Barbora Weinbergerova, Jiri Mayer, Pierre-Yves Dumas, Sarah Bertoli, Eric Delabesse, Christian Récher, Arnaud Pigneux, Tobias Herold, Arnold Ganser, Hartmut Döhner, Martin Bornhäuser, Christian Thiede, Christoph Röllig

Blood (2024) 144 (Supplement 1): 2934.

https://doi.org/10.1182/blood-2024-201945

Published: 2024

Journal Articles

Subclonal KIT D816V Mutations Are Prevalent in Chronic Myelomonocytic Leukemia and Correlate with Distinct Phenotypic Features

Blood (2022) 140 (Supplement 1): 9824–9827.

https://doi.org/10.1182/blood-2022-164816

Published: 2022

Journal Articles

TP53 and Complex Karyotype Represent a Very High-Risk Group in Myelofibrosis Undergoing Hematopoietic Stem Cell Transplantation: An International Collaborative Analysis

Nico Gagelmann, Anita Badbaran, Rachel Beth Salit, Thomas Schroeder, Carmelo Gurnari, Simona Pagliuca, Arnold Ganser, Christina Rautenberg, Bruno Cassinat, Felicitas R Thol, Christine Wolschke, Marie Robin, Michael Heuser, Marie Thérèse Rubio, Jaroslaw P. Maciejewski, Hans Christian Reinhardt, Bart L. Scott, Nicolaus Kroeger

Blood (2022) 140 (Supplement 1): 828–829.

https://doi.org/10.1182/blood-2022-158900

Published: 2022

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2025 Update on MRD in Acute Myeloid Leukemia: A Consensus Document from the ELN-DAVID MRD Working Party

Proteogenomic analysis of NPM1-mutated AML reveals clinical heterogeneity related to differentiation states and mitochondrial metabolism

Allogeneic CAR-T therapy AVC-201 in AML positive for CD123

Establishing contemporary benchmarks for Acute Myeloid Leukemia outcomes and measurable residual disease: Real-world data utilization from the ELN-david MRD international working group

Clinical characteristics and comutational landscape of CSF3R mutations in acute myeloid leukemia

Monitoring of CNS involvement in AML using ultrahigh-sensitivity next-generation sequencing of cell-free DNA

Umbilical cord blood CD34+ hematopoietic stem cell-derived natural killer cells in Acute Myeloid Leukemia – a phase I clinical study

Adding eltrombopag to immunosuppressive treatment with cyclosporine as front-line therapy for moderate aplastic anemia improves trilineage hematologic response: One-year analysis of the randomised, placebo-controlled, double-blind Phase III trial eltrombopag for moderate aplastic anemia (EMAA Trial)

CPX-351 in Down syndrome-associated Myeloid Leukemia: Results and Prognostic Factors from the Phase 3 ML-DS 2018 Trial

Intra-Tumor Heterogeneity in Core-Binding Factor Acute Myeloid Leukemia

Prognostic Role of NGS-Based MRD Assessment in FLT3 -TKD Mutated Patients with Acute Myeloid Leukemia

Prognostic Impact of Subclinical FLT3 -ITD Microclones in Patients with Acute Myeloid Leukemia

The Prognostic Impact of Myelodysplasia-Related Gene Mutations in Acute Myeloid Leukemia with FLT3 -ITD Mutations

A Molecular-Based Ecosystem to Improve Personalized Medicine in Patients with Chronic Myelomonocytic Leukemia (CMML)

CAR-T Cell Therapy for Acquired Hemophilia A

A Phase 1, Open-Label, Dose Escalation and Dose Expansion Study of Cln-049 for the Treatment of Acute Myeloid Leukemia Patients with Measurable Residual Disease

Reliable Assessment of Iron Deficiency in Patients with Myeloproliferative Neoplasms through Fluorescence Spectroscopy-Based Measurement of Zinc Protoporphyrin (ZPP)

The Differential Impact of Secondary-Type Mutations in a Multinational Cohort of 5311 Intensively Treated Acute Myeloid Leukemia Patients

Subclonal KIT D816V Mutations Are Prevalent in Chronic Myelomonocytic Leukemia and Correlate with Distinct Phenotypic Features

TP53 and Complex Karyotype Represent a Very High-Risk Group in Myelofibrosis Undergoing Hematopoietic Stem Cell Transplantation: An International Collaborative Analysis

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