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Maher Hanoun
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Journal Articles

Secondary-Type Mutations Do Not Impact the Favorable Outcome of NPM1 -Mutated Acute Myeloid Leukemia Patients - Results from a Large Cohort of Intensively Treated Patients

Marius Bill, Jan-Niklas Eckardt, Christian Rausch, Klaus H Metzeler, Karsten Spiekermann, Sebastian Stasik, Tim Sauer, Sebastian Scholl, Andreas Hochhaus, Martina Crysandt, Tim H. Brümmendorf, Utz Krug, Bernhard Wörmann, Wolfgang Hiddemann, Dennis Görlich, Maria Cristina Sauerland, Björn Steffen, Hermann Einsele, Andreas Neubauer, Andreas Burchert, Kerstin Schaefer-Eckart, Wolfgang E. Berdel, Christoph Schliemann, Stefan W. Krause, Mathias Hanel, Maher Hanoun, Martin Kaufmann, Lars Fransecky, Jan Braess, Leo Ruhnke, Johannes Schetelig, Jan Moritz Middeke, Hubert Serve, Claudia D Baldus, Uwe Platzbecker, Carsten Müller-Tidow, Martin Bornhäuser, Tobias Herold, Christian Thiede, Christoph Röllig
Journal: Blood
Blood (2023) 142 (Supplement 1): 721.
https://doi.org/10.1182/blood-2023-186160
Published: 2023
Journal Articles

Mimicking Clinical Trials with Synthetic Acute Myeloid Leukemia Patients Using Generative Artificial Intelligence

Jan-Niklas Eckardt, Waldemar Hahn, Christoph Röllig, Sebastian Stasik, Uwe Platzbecker, Carsten Müller-Tidow, Hubert Serve, Claudia D Baldus, Christoph Schliemann, Kerstin Schäfer-Eckart, Maher Hanoun, Martin Kaufmann, Andreas Burchert, Christian Thiede, Johannes Schetelig, Martin Bornhäuser, Markus Wolfien, Jan Moritz Middeke
Journal: Blood
Blood (2023) 142 (Supplement 1): 2268.
https://doi.org/10.1182/blood-2023-179817
Published: 2023
Journal Articles

Venetoclax Plus High-Dose Cytarabine and Mitoxantrone (HAM-Ven) As Salvage Treatment for Relapsed/Refractory AML: Updated Results of the Phase-I/II SAL Relax Trial

Leo Ruhnke, Christoph Schliemann, Jan-Henrik Mikesch, Matthias Stelljes, Lars Fransecky, Björn Steffen, Martin Kaufmann, Andreas Burchert, Andreas Rank, Maher Hanoun, Alexander Höllein, Sabrina Kraus, Mathias Hänel, Kerstin Schäfer-Eckart, Annett Haake, Frank Fiebig, Sven Zukunft, Jan Moritz Middeke, Désirée Kunadt, Johannes Schetelig, Malte von Bonin, Maximilian Alexander Röhnert, Uta Oelschlägel, Friedrich Stölzel, Claudia D Baldus, Hubert Serve, Martin Wermke, Martin Bornhäuser, Christoph Röllig
Journal: Blood
Blood (2023) 142 (Supplement 1): 160.
https://doi.org/10.1182/blood-2023-184445
Published: 2023
Journal Articles

Venetoclax Plus High-Dose Cytarabine and Mitoxantrone As Feasible and Effective Novel Treatment for Relapsed AML: Results of the Phase-I SAL Relax Trial

Christoph Röllig, Lars Fransecky, Maher Hanoun, Björn Steffen, Sabrina Kraus, Christoph Schliemann, Annett Haake, Frank Fiebig, Sven Zukunft, Nael Alakel, Jan Moritz Middeke, Martin Bornhaeuser, Friedrich Stoelzel, Johannes Schetelig, Leo Ruhnke, Michael Kramer, Malte Von Bonin, Maximilian Alexander Röhnert, Uta Oelschlägel, Claudia D. Baldus, Hubert Serve, Martin Wermke
Journal: Blood
Blood (2022) 140 (Supplement 1): 3327–3328.
https://doi.org/10.1182/blood-2022-159897
Published: 2022
Journal Articles

Single Versus Double Induction with "7+3" Containing 60 Versus 90 Mg Daunorubicin for Newly Diagnosed AML: Results from the Randomized Controlled SAL Dauno-Double Trial

Christoph Röllig, Björn Steffen, Christoph Schliemann, Jan-Henrik Mikesch, Nael Alakel, Regina Herbst, Mathias Haenel, Richard Noppeney, Maher Hanoun, Martin Kaufmann, Zdenek Racil, Kerstin Schäfer-Eckart, Tim Sauer, Andreas Neubauer, Claudia D. Baldus, Jolana Mertova, Edgar Jost, Dirk Niemann, Jan Novak, Stefan W. Krause, Sebastian Scholl, Andreas Hochhaus, Gerhard Held, Tomáš Szotkowski, Christoph Schmid, Andreas Rank, Lars Fransecky, Michael Kramer, Frank Fiebig, Annett Haake, Friedrich Stoelzel, Johannes Schetelig, Jan Moritz Middeke, Uwe Platzbecker, Christian Thiede, Carsten Müller-Tidow, Wolfgang E. Berdel, Hubert Serve, Gerhard Ehninger, Jiří Mayer, Martin Bornhaeuser
Journal: Blood
Blood (2022) 140 (Supplement 1): 523–525.
https://doi.org/10.1182/blood-2022-157126
Published: 2022
Journal Articles

Venetoclax-Based Salvage Therapy Improves Outcome in Relapsed/Refractory AML Patients Eligible for Intensive Treatment: A Propensity Score Matching Analysis

Julia M. Unglaub, Richard F. Schlenk, Maher Hanoun, H. Christian Reinhardt, Jan Moritz Middeke, Kerstin Schäfer-Eckart, Björn Steffen, Stefan W. Krause, Christoph Schliemann, Martin Kaufmann, Mathias Haenel, Edgar Jost, Martina Crysandt, Lars Fransecky, Hermann Einsele, Sabrina Kraus, Dirk Niemann, Andreas Neubauer, Ruth Seggewiss-Bernhardt, Sebastian Scholl, Stefan Klein, Christoph Schmid, Markus Schaich, Uwe Platzbecker, Claudia D. Baldus, Martin Bornhaeuser, Hubert Serve, Christoph Röllig, Michael Kramer, Elena Katelari, Maike Janssen, Caroline Pabst, Thomas Luft, Peter Dreger, Carsten Müller-Tidow, Tim Sauer
Journal: Blood
Blood (2022) 140 (Supplement 1): 3317–3319.
https://doi.org/10.1182/blood-2022-167677
Published: 2022
Journal Articles

Venetoclax and Hypomethylating Agents Followed By Allogeneic Stem Cell Transplantation in Patients with Acute Myeloid Leukemia

Christina Rautenberg, Anja Ragette, Jennifer Kaivers, Nina Neuendorff, Maher Hanoun, Hans Christian Reinhardt, Thomas Schroeder
Journal: Blood
Blood (2022) 140 (Supplement 1): 12943–12944.
https://doi.org/10.1182/blood-2022-169893
Published: 2022
Journal Articles

Inotuzumab Ozogamicin Induction Followed By Standard Chemotherapy Yields High Remission Rates and Promising Survival in Older (>55 Years) Patients with De Novo B-Lymphoblastic Leukemia (GMALL-Initial1 Trial)

Matthias Stelljes, Nael Alakel, Ralph Wäsch, Sebastian Scholl, Kathrin Nachtkamp, Andreas Rank, Mathias Haenel, Bernd Spriewald, Maher Hanoun, Sonja Martin, Katjana Schwab, Julian Knaden, Lena Reiser, Julia Marx, Klaus Wethmar, Tim Sauer, Wolfgang E. Berdel, Georg Lenz, Monika Brüggemann, Simon Raffel, Nicola Goekbuget
Journal: Blood
Blood (2022) 140 (Supplement 1): 510–512.
https://doi.org/10.1182/blood-2022-162235
Published: 2022
Journal Articles

Results of the Risk-Adapted, MRD-Stratified GMALL Trial 08/2013 in 281 T-ALL / T-Lbl Patients: Excellent Outcome of Standard Risk Thymic T-ALL

Nicola Goekbuget, Walter Fiedler, Nael Alakel, Max S. Topp, Maher Hanoun, Björn Steffen, Ralph Wäsch, Andreas Viardot, Kathrin Nachtkamp, Matthias Stelljes, Hendrik Poeck, Vladan Vucinic, Boris Böll, Joachim Beck, Lars Fransecky, Knut Wendelin, Folker Schneller, Christoph Faul, Veit L Buecklein, Lena Reiser, Monika Brüggemann, Hubert Serve, Stefan Schwartz
Journal: Blood
Blood (2022) 140 (Supplement 1): 115–117.
https://doi.org/10.1182/blood-2022-158381
Published: 2022
Journal Articles

Prediction of Complete Remission and Survival in Acute Myeloid Leukemia Using Supervised Machine Learning

Jan-Niklas Eckardt, Christoph Rollig, Michael Kramer, Sebastian Stasik, Julia-Annabell Georgi, Peter Heisig, Frank P. Kroschinsky, Johannes Schetelig, Uwe Platzbecker, Carsten Müller-Tidow, Tim Sauer, Hubert Serve, Claudia D. Baldus, Kerstin Schaefer-Eckart, Martin Kaufmann, Stefan W. Krause, Mathias Haenel, Christoph Schliemann, Maher Hanoun, Christian Thiede, Martin Bornhaeuser, Karsten Wendt, Jan Moritz Middeke
Journal: Blood
Blood (2021) 138 (Supplement 1): 108.
https://doi.org/10.1182/blood-2021-149582
Published: 2021
Journal Articles

Real-World Experience of CPX-351 As First-Line Treatment in 188 Patients with Acute Myeloid Leukemia

Christina Rautenberg, Friedrich Stölzel, Christoph Röllig, Matthias Stelljes, Verena I Gaidzik, Michael Lauseker, Oliver Kriege, Mareike Verbeek, Julia M. Unglaub, Felicitas Thol, Stefan W. Krause, Mathias Haenel, Charlotte Neuerburg, Vladan Vucinic, Christian Jehn, Julia Severmann, Maxi Wass, Lars Fransecky, Jens Chemnitz, Udo Holtick, Kerstin Schäfer-Eckart, Josephine Schröder, Sabrina Kraus, William Hermann Krüger, Ulrich Kaiser, Sebastian Scholl, Lea Henning, Guido Kobbe, Rainer Haas, Nael Alakel, Maximilian Alexander Röhnert, Katja Sockel, Maher Hanoun, Uwe Platzbecker, Tobias A. W. Holderried, Anke Morgner, Michael Heuser, Tim Sauer, Katharina S. Goetze, Eva Maria Wagner, Konstanze Döhner, Hartmut Döhner, Christoph Schliemann, Johannes Schetelig, Martin Bornhäuser, Ulrich Germing, Thomas Schroeder, Moritz Moritz Middeke
Journal: Blood
Blood (2021) 138 (Supplement 1): 33.
https://doi.org/10.1182/blood-2021-153440
Published: 2021
Journal Articles

Venetoclax-Azacitidine As Salvage Therapy and Bridge to Allogeneic Cell Transplantation in Relapsed/Refractory AML Compared to Historical Data of the SAL Registry Study

Julia M. Unglaub, Richard F. Schlenk, Maher Hanoun, H. Christian Reinhardt, Jan Moritz Middeke, Kerstin Schäfer-Eckart, Björn Steffen, Stefan W. Krause, Christoph Schliemann, Martin Kaufmann, Mathias Haenel, Edgar Jost, Martina Crysandt, Lars Fransecky, Sabrina Kraus, Hermann Einsele, Dirk Niemann, Andreas Neubauer, Ruth Seggewiss-Bernhardt, Sebastian Scholl, Stefan Klein, Christoph Schmid, Markus Schaich, Uwe Platzbecker, Claudia D. Baldus, Martin Bornhäuser, Hubert Serve, Christoph Rollig, Michael Kramer, Elena Katelari, Maike Janssen, Caroline Pabst, Thomas Luft, Peter Dreger, Carsten Müller-Tidow, Tim Sauer
Journal: Blood
Blood (2021) 138 (Supplement 1): 4418.
https://doi.org/10.1182/blood-2021-151287
Published: 2021
Journal Articles

Intensified Cytarabine Dose during Consolidation Therapy in AML Patients Under 65 Years Is Not Associated with Survival Benefit

Maher Hanoun, Leo Ruhnke, Michael Kramer, Kerstin Schäfer-Eckhard, Björn Steffen, Tim Sauer, Stefan W. Krause, Christoph Schliemann, Martin Kaufmann, Mathias Haenel, Edgar Jost, Tim H Brummendorf, Lars Fransecky, Sabrina Kraus, Hermann Einsele, Dirk Niemann, Andreas Neubauer, Johannes Kullmer, Ruth Seggewiss-Bernhard, Martin Goerner, Gerhard Held, Ulrich Kaiser, Sebastian Scholl, Hans Christian Reinhardt, Uwe Platzbecker, Claudia D. Baldus, Carsten Mueller-Tidow, Martin Bornhaeuser, Hubert Serve, Christoph Rollig
Journal: Blood
Blood (2021) 138 (Supplement 1): 1242.
https://doi.org/10.1182/blood-2021-146606
Published: 2021
Journal Articles

Characteristics and Outcome of Patients with Acute Myeloid Leukemia and Trisomy 4

Sabine Kayser, David Martínez-Cuadrón, Maher Hanoun, Friedrich Stölzel, Cristina Gil, H. Christian Reinhardt, Eliana Aguiar, Kerstin Schäfer-Eckart, Juan Miguel Bergua Burgues, Björn Steffen, Teresa Bernal, Stefan W. Krause, Rosalia Riaza, Christoph Schliemann, Jose Cervera, Martin Kaufmann, Laura Torres, Mathias Haenel, Evelyn Acuña-Cruz, Edgar Jost, Jesús Lorenzo Algarra, Martina Crysandt, Lars Fransecky, Javier Cornago Navascués, Sabrina Kraus, Joaquin Martinez-Lopez, Hermann Einsele, Dirk Niemann, Andreas Neubauer, Ruth Seggewiss-Bernhardt, Sebastian Scholl, Stefan Klein, Christoph Schmid, Markus Schaich, Martin Schmidt-Hieber, Anthony D. Ho, Uwe Platzbecker, Claudia D. Baldus, Carsten Müller-Tidow, Christian Thiede, Martin Bornhäuser, Hubert Serve, Mark Levis, Pau Montesinos, Christoph Röllig, Richard F. Schlenk
Journal: Blood
Blood (2021) 138 (Supplement 1): 1307.
https://doi.org/10.1182/blood-2021-150281
Published: 2021
Journal Articles

Impact of Body Mass Index on Patient Outcome in Acute Myeloid Leukemia Patients Receiving Intensive Induction Therapy: A Real-World Registry Experience

Julius Christoph Enssle, Sebastian Wolf, Sebastian Scheich, Sarah Weber, Michael Kramer, Leo Ruhnke, Christoph Schliemann, Jan-Henrik Mikesch, Stefan W. Krause, Tim Sauer, Maher Hanoun, Hans Christian Reinhardt, Sabrina Kraus, Martin Kaufmann, Mathias Haenel, Lars Fransecky, Andreas Burchert, Andreas Neubauer, Martina Crysandt, Edgar Jost, Dirk Niemann, Kerstin Schäfer-Eckhard, Gerhard Held, Ulrich Kaiser, Maxi Wass, Markus Schaich, Carsten Müller-Tidow, Uwe Platzbecker, Claudia D. Baldus, Martin Bornhäuser, Christoph Rollig, Hubert Serve, Björn Steffen
Journal: Blood
Blood (2021) 138 (Supplement 1): 3370.
https://doi.org/10.1182/blood-2021-145917
Published: 2021
Journal Articles

Gemtuzumab Ozogamicin Plus Midostaurin in Combination with Standard Intensive Induction Therapy in Newly Diagnosed AML: Results from a Phase-I Study

Christoph Röllig, Christoph Schliemann, Jan-Henrik Mikesch, Lars Fransecky, Claudia D. Baldus, Björn-Niklas Heydrich, Maher Hanoun, Richard Noppeney, Sebastian Scholl, Ulf Schnetzke, Kerstin Schäfer-Eckart, Knut Wendelin, Martin Wermke, Manja Reimann, Frank Fiebig, Theresa Kretschmann, Friedrich Stoelzel, Nael Alakel, Martin Bornhäuser
Journal: Blood
Blood (2021) 138 (Supplement 1): 2324.
https://doi.org/10.1182/blood-2021-150069
Published: 2021
Journal Articles

Final Induction Therapy Results of an Open Label Phase II Study Using Inotuzumab Ozogamicin for Induction Therapy, Followed By a Conventional Chemotherapy Based Consolidation and Maintenance Therapy in Patients Aged 56 Years and Older with Acute B-Lymphoblastic Leukemia (INITIAL-1 trial)

Matthias Stelljes, Nael Alakel, Ralph Wäsch, Sebastian Scholl, Kathrin Nachtkamp, Andreas Rank, Mathias Haenel, Bernd Spriewald, Maher Hanoun, Sonja Martin, Katjana Schwab, Julian Knaden, Julia Marx, Klaus Wethmar, Tim Sauer, Wolfgang E. Berdel, Georg Lenz, Martin Dugas, Nicola Goekbuget, Monika Brueggemann, Simon Raffel
Journal: Blood
Blood (2021) 138 (Supplement 1): 2300.
https://doi.org/10.1182/blood-2021-145553
Published: 2021
Journal Articles

First Results of the Risk-Adapted, MRD-Stratified GMALL Trial 08/2013 in 705 Adults with Newly Diagnosed Acute Lymphoblastic Leukemia/Lymphoma (ALL/LBL)

Nicola Goekbuget, Matthias Stelljes, Andreas Viardot, Kathrin Nachtkamp, Björn Steffen, Folker Schneller, Nael Alakel, Max Topp, Boris Böll, Christoph Faul, Karsten Spiekermann, Knut Wendelin, Maher Hanoun, Ralph Wäsch, Joachim Beck, Sonja Martin, Vladan Vucinic, Claudia D. Baldus, Monika Brüggemann, Thomas Burmeister, Heike Pfeifer, Stefan Schwartz, Lena Baumann, Diana Tichy, Hubert Serve, Walter Fiedler
Journal: Blood
Blood (2021) 138 (Supplement 1): 362.
https://doi.org/10.1182/blood-2021-146306
Published: 2021
Journal Articles

Remission and Survival after Single Versus Double Induction with 7+3 for Newly Diagnosed Acute Myeloid Leukemia: Results from the Planned Interim Analysis of Randomized Controlled SAL-Daunodouble Trial

Christoph Röllig, MD MSC, Björn Steffen, MD, Nael Alakel, MD, Regina Herbst, MD, Richard Noppeney, MD, Maher Hanoun, MD PhD, Zdenek Racil, MD PhD, Kerstin Schäfer-Eckart, MD, Alwin Krämer, MD, Andreas Neubauer, Professor Dr, Claudia D Baldus, MD, Christoph Schliemann, Prof., MD, Martin Kaufmann, MD, Jolana Mertova, Edgar Jost, Dirk Niemann, MD, Jan Novak, Stefan W Krause, Sebastian Scholl, Gerhard Held, Professor Dr, Stefani B. Parmentier, Tomáš Szotkowski, MD PhD, Pavel Zak, MD, Andreas Rank, PD Dr, Maxi Wass, MD, Sebastian Buske, Michael Kramer, Frank Fiebig, Annett Haake, Johannes Schetelig, MDMSc, Uwe Platzbecker, Christian Thiede, MD, Carsten Müller-Tidow, MD, Wolfgang E. Berdel, Prof., MD, Hubert Serve, MD PhD, Gerhard Ehninger, MD, Jiri Mayer, Martin Bornhäuser, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 1–3.
https://doi.org/10.1182/blood-2020-140246
Published: 2020
Journal Articles

Acute Myeloid Leukemia Induced Remodelling of the Human Bone Marrow Niche Predicts Clinical Outcome

Yiyang Chen, Yasmin Zaun, MD, Lucas Arnold, Kerstin Weissenfels, Kurt Werner Schmid, Ludger Klein-Hitpass, PhD, Anthony Squire, Stefanie Bertram, MD, Ulrich Duehrsen, MD, Maher Hanoun, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3851.
https://doi.org/10.1182/blood-2018-99-116317
Published: 2018