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Johannes Duell
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Journal Articles

Spatial transcriptomics reveals profound subclonal heterogeneity and T-cell dysfunction in extramedullary myeloma

Mara John, Moutaz Helal, Johannes Duell, Greta Mattavelli, Emilia Stanojkovska, Nazia Afrin, Alexander M. Leipold, Maximilian J. Steinhardt, Xiang Zhou, David Žihala, Anjana Anilkumar Sithara, Julia Mersi, Johannes M. Waldschmidt, Christine Riedhammer, Sofie-Katrin Kadel, Marietta Truger, Rudolf A. Werner, Claudia Haferlach, Hermann Einsele, Kai Kretzschmar, Tomáš Jelínek, Andreas Rosenwald, K. Martin Kortüm, Angela Riedel, Leo Rasche
Journal: Blood
Blood (2024) 144 (20): 2121–2135.
https://doi.org/10.1182/blood.2024024590
Published: 2024
Includes: Supplemental data
Journal Articles

Sequential antigen loss and branching evolution in lymphoma after CD19- and CD20-targeted T-cell–redirecting therapy

Johannes Duell, Alexander M. Leipold, Silke Appenzeller, Viktoria Fuhr, Hilka Rauert-Wunderlich, Matteo Da Via, Oliver Dietrich, Christophe Toussaint, Fabian Imdahl, Florian Eisele, Nazia Afrin, Lars Grundheber, Hermann Einsele, Niels Weinhold, Andreas Rosenwald, Max S. Topp, Antoine-Emmanuel Saliba, Leo Rasche
Journal: Blood
Blood (2024) 143 (8): 685–696.
https://doi.org/10.1182/blood.2023021672
Published: 2024
Includes: Supplemental data
Journal Articles

Estimates of Survival and Life Expectancy with Tafasitamab Plus Lenalidomide in the L-Mind Study Compared with Real-World Standard-of-Care for Patients with Relapsed/Refractory Diffuse Large B-Cell Lymphoma

Johannes Duell, Martin Dreyling, Gianluca Gaidano, Nagesh Kalakonda, Eva Maria Gonzalez Barca, Anna Marina Liberati, Zsolt Nagy, Daniel Moik, Mirko Vukcevic, Aasim Amin, Abhishek Bakuli
Journal: Blood
Blood (2023) 142 (Supplement 1): 6286.
https://doi.org/10.1182/blood-2023-174043
Published: 2023
Journal Articles

Prolonged Cytopenia Following CAR T-Cell Therapy in Relapsed/Refractory Multiple Myeloma: A Prospective Comprehensive Biomarker Study

Xiang Zhou, Vivien Wagner, Emilia Stanojkovska, Christine Riedhammer, Xianghui Xiao, Mara John, Lukas Scheller, Umair Munawar, Seungbin Han, Johannes M Waldschmidt, Max S. Topp, Johannes Duell, Hermann Einsele, Angela Riedel, Martin Kortüm, Leo Rasche
Journal: Blood
Blood (2023) 142 (Supplement 1): 95.
https://doi.org/10.1182/blood-2023-180534
Published: 2023
Journal Articles

The Impact of Treatment-Free Intervals on T-Cell Exhaustion and Clonotypic Diversity in Myeloma Patients Treated with BCMA Bispecific Antibodies

Florian Eisele, Nazia Afrin, Emilia Stanojkovska, Mara John, Moutaz Helal, Lars Grundheber, Philipp Weis, Christine Riedhammer, Sofie-Katrin Kadel, Max Steinhardt, Johannes Duell, Johannes M Waldschmidt, Hermann Einsele, Angela Riedel, K. Martin Kortüm, Leo Rasche
Journal: Blood
Blood (2023) 142 (Supplement 1): 1938.
https://doi.org/10.1182/blood-2023-189042
Published: 2023
Journal Articles

Tafasitamab and Lenalidomide in Relapsed/Refractory B-Cell Lymphoma: A Multicenter Retrospective Real-World-Study of Patients from Germany and Austria

Anna Ruckdeschel, Koemm Sabrina, Max S. Topp, Richard Greil, Thomas Melchardt, Georg Lenz, Andrea Kerkhoff, Evgenii Shumilov, Georg Hess, Marta Baumgaertner, Lorenz Thurner, Igor Age Kos, Stephanie Mayer, Francis A. Ayuk, Rolf Krause, Marco Herling, Vladan Vucinic, Claudia Chapuy, Gerald Illerhaus, Markus Knott, Andreas Viardot, Alexander Grunenberg, Sascha Dietrich, Leandra Caille, Mareike C. Tometten, Hyunyee Rosa Cho, Julia Scholz, Fabian Mueller, Katharina Prochazka, Bjoern Chapuy, David Böckle, Bastian von Tresckow, Natalie Schub, Götz Gelbrich, Hermann Einsele, Johannes Duell
Journal: Blood
Blood (2023) 142 (Supplement 1): 1771.
https://doi.org/10.1182/blood-2023-185992
Published: 2023
Journal Articles

Real World Results of Brexucabtagene Autoleucel for Patients with Relapsed/Refractory Mantle Cell Lymphoma - First German/Swiss Analysis

Georg Hess, Vladan Vucinic, Kai Rejeski, Enver Aydilek, Linda Simon, Olaf Penack, Christian Koenecke, Malte von Bonin, Bastian von Tresckow, Martin Fehr, Christiane Pott, Stephan Stilgenbauer, Corinna Leng, Roland Schroers, Johannes Duell, Reinhard Marks, Fabian Mueller, Uta Brunnberg, Andrea Kerkhoff, Anke Ohler, Eva-Maria Wagner Drouet, Irene Schmidtmann, Matthias Theobald, Martin Dreyling, Peter Dreger
Journal: Blood
Blood (2023) 142 (Supplement 1): 4394.
https://doi.org/10.1182/blood-2023-182415
Published: 2023
Journal Articles

Functional Imaging As a Key Diagnostic Tool in the Follow-up of RRMM Patients after CAR-T-Cell Therapy

Sven Schimanski, Hannah Hornburger, Sofie-Katrin Kadel, Anna Marie Ruckdeschel, Florian Eisele, Daniela Schneider, Anke Heidemeier, Andreas Buck, Rudolf Werner, Johannes M Waldschmidt, Paula Tabares, Andreas Beilhack, Johannes Duell, Hermann Einsele, K. Martin Kortüm, Max S. Topp, Leo Rasche
Journal: Blood
Blood (2023) 142 (Supplement 1): 3372.
https://doi.org/10.1182/blood-2023-188501
Published: 2023
Journal Articles

Safety and efficacy of tafasitamab with or without lenalidomide added to first-line R-CHOP for DLBCL: the phase 1b First-MIND study

Clinical Trials & Observations
David Belada, Katerina Kopeckova, Juan Miguel Bergua Burgues, Don Stevens, Marc André, Ernesto Perez Persona, Petra Pichler, Philipp B. Staber, Marek Trneny, Johannes Duell, Maeve Waldron-Lynch, Steve Wagner, Amitava Mukhopadhyay, Maren Dirnberger-Hertweck, John M. Burke, Grzegorz S. Nowakowski
Journal: Blood
Blood (2023) 142 (16): 1348–1358.
https://doi.org/10.1182/blood.2023020637
Published: 2023
Includes: Supplemental data
Journal Articles

Subcutaneous Epcoritamab in Novel Combinations with Antineoplastic Agents Among Patients with B-Cell Non-Hodgkin Lymphoma in a Phase 1b/2, Multicenter, Open-Label Study: Assessing Safety, Tolerability, and Preliminary Efficacy (EPCORE NHL-5)

Laurie H. Sehn, Johannes Duell, Irit Avivi, Joshua Brody, Dok Hyun Yoon, Brian Elliot, Satya R. Siddani, Yang Bai, Apurvasena Parikh, Mostafa M. Seliem, Minh Dinh, Alan P. Skarbnik
Journal: Blood
Blood (2022) 140 (Supplement 1): 12108–12109.
https://doi.org/10.1182/blood-2022-157596
Published: 2022
Journal Articles

Pseudoprogression and Sarcoidosis-like Phenomena after CART-Cells and Bispecific Antibodies in Multiple Myeloma

Alexander Leipold, Rudolf Werner, Johannes Duell, Pius Jung, Mara John, Emilia Stanojkovska, Xiang Zhou, Anna Ruckdeschel, Oliver Dietrich, Fabian Imdahl, Tobias Krammer, Andreas Buck, Julia Mersi, Hermann Einsele, K. Martin Kortuem, Antoine-Emmanuel Saliba, Leo Rasche
Journal: Blood
Blood (2022) 140 (Supplement 1): 10020–10021.
https://doi.org/10.1182/blood-2022-168836
Published: 2022
Journal Articles

L-Mind: A Safety and Efficacy Analysis of Tafasitamab in Patients with Relapsed/Refractory Diffuse Large B-Cell Lymphoma (R/R DLBCL) Receiving Treatment for at Least 2 Years

Johannes Duell, Wojciech Jurczak, Anna Marina Liberati, Janusz Halka, Esther Pena Carbó, Pau Abrisqueta Costa, Kami J. Maddocks, Martin Dreyling, Andreas Rosenwald, Abhishek Bakuli, Aasim Amin, Konstantin Gurbanov, Gilles Salles
Journal: Blood
Blood (2022) 140 (Supplement 1): 6596–6598.
https://doi.org/10.1182/blood-2022-159983
Published: 2022
Journal Articles

Spatial Transcriptomics Reveals a Multi Cellular Ecosystem in Extramedullary Multiple Myeloma

Moutaz Helal, Mara John, Emilia Stanojkovska, Greta Mattavelli, Lars Grundheber, Alexander Leipold, Nazia Afrin, Christine Riedhammer, Johannes Duell, Max Johannes Steinhardt, Julia Mersi, Hermann Einsele, Kai Kretzschmar, K. Martin Kortuem, Angela Riedel, Leo Rasche
Journal: Blood
Blood (2022) 140 (Supplement 1): 7060–7061.
https://doi.org/10.1182/blood-2022-168700
Published: 2022
Journal Articles

First-Mind: Final Analysis from a Phase Ib, Open-Label, Randomized Study to Assess Safety of Tafasitamab or Tafasitamab + Lenalidomide in Addition to R-CHOP in Patients with Newly Diagnosed Diffuse Large B-Cell Lymphoma

Grzegorz S. Nowakowski, Johannes Duell, Katerina Kopeckova, Marek Trneny, Christiane Pott, Mouhamad Khouja, John M. Burke, Maeve Waldron-Lynch, Steve Wagner, Amitava Mukhopadhyay, Derek Blair, David Belada
Journal: Blood
Blood (2022) 140 (Supplement 1): 3731–3733.
https://doi.org/10.1182/blood-2022-163160
Published: 2022
Journal Articles

Expression of CD20 Affects Early MRD Response to Rituximab in Adult B Cell Precursor Lymphoblastic Leukemia of the GMALL 08/2013 Trial

Monika Szczepanowski, Johanna Richter, Miriam Kelm, Heiko Trautmann, Britta Kehden, Matthias Ritgen, Christoph Faul, Kathrin Nachtkamp, Björn Steffen, Andreas Viardot, Johannes Gärtner, Johannes Duell, Claudia D. Baldus, Stefan Schwartz, Nicola Goekbuget, Monika Brüggemann
Journal: Blood
Blood (2021) 138 (Supplement 1): 2301.
https://doi.org/10.1182/blood-2021-150375
Published: 2021
Journal Articles

The Addition of Rituximab to Cyclophosphamide, Doxorubicine, Vincristine and Prednisone (CHOP) Prolongs Overall Survival in Previously Untreated Mantle Cell Lymphoma: A Long Term Pooled Trials Analysis

Luca Fischer, Linmiao Jiang, Joerg Bittenbring, Kai Hübel, Christian Schmidt, Johannes Duell, Bernd Metzner, Jürgen Krauter, Bertram Glass, Andreas Hüttmann, Kerstin Schaefer-Eckart, Wolfram Klapper, Wolfgang Hiddemann, Michael Unterhalt, Martin H. Dreyling, Eva Hoster
Journal: Blood
Blood (2021) 138 (Supplement 1): 3551.
https://doi.org/10.1182/blood-2021-148074
Published: 2021
Journal Articles

Efficacy of Tafasitamab (MOR208) Combined with Lenalidomide in Patients with High-Risk Relapsed or Refractory Diffuse Large B-Cell Lymphoma in the L-Mind Study

Eva González-Barca, MD PhD, Johannes Duell, MD, Federica Cavallo, Juan-Manuel Sancho, MD PhD, Zsolt Nagy, MD PhD, Pau Abrisqueta, MD PhD, Carlos Panizo, MD PhD, Marinela Augustin, Johannes Weirather, PhD, Sumeet Ambarkhane, MD MBBS, Kami J. Maddocks, MD, Nagesh Kalakonda, MD, Gilles Salles, MDPhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 1–2.
https://doi.org/10.1182/blood-2020-140294
Published: 2020
Journal Articles

Odronextamab (REGN1979), a Human CD20 x CD3 Bispecific Antibody, Induces Durable, Complete Responses in Patients with Highly Refractory B-Cell Non-Hodgkin Lymphoma, Including Patients Refractory to CAR T Therapy

Rajat Bannerji, MDPhD, John N. Allan, MD, Jon E. Arnason, MD, Jennifer R. Brown, MD PhD, Ranjana Advani, MD, Stephen M. Ansell, MD PhD, Susan M. O'Brien, MD, Johannes Duell, MD, Peter Martin, FRCPC, MD MS, Robin M. Joyce, MD, Jingjin Li, PhD, Dina M. Flink, PhD, Min Zhu, PhD, David M. Weinreich, MD, George D. Yancopoulos, MD PhD, Andres Sirulnik, MD PhD, Aafia Chaudhry, MD MBA, MS, Srikanth R. Ambati, MBBS, MD, Max S. Topp, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 42–43.
https://doi.org/10.1182/blood-2020-136659
Published: 2020
Journal Articles

Polatuzumab Vedotin in Relapsed and Refractory (r/r) Large B-Cell Lymphoma (LBCL): Real-World Data of the German National Compassionate Use Program (CUP)

Nora Liebers, MD, Johannes Duell, MD, Daniel Nörenberg, MD, Eva Kaebisch, MD, Andrea Kerkhoff, MD, Fabian Acker, MD, Stephan Fuhrmann, MD, Corinna Leng, MD PhD, Manfred Welslau, MD, Jens Chemnitz, MD, Jan Moritz Middeke, MD, Thomas Weber, MD, Ralf Ulrich Trappe, MD, Roald Pfannes, MD, Ruediger Liersch, MD, Christian Spoer, MD, Niklas Gebauer, MD, Stefan Fuxius, MD, Léandra Caillé, Christiane Pott, MD PhD, Christian Koenecke, MD, Udo Holtick, Thomas Geer, MD, Ulrich Keller, MD, Rainer Claus, MD, Dimitrios Mougiakakos, MD, Stephanie Mayer, MD, Andreas Hüttmann, MD, Arne Trummer, MD, Gerald Wulf, MD, Uta Brunnberg, MD, Lars Bullinger, MD, Georg Hess, MD, Carsten Mueller-Tidow, MD, Bertram Glass, MD, Georg Lenz, Peter Dreger, MD, Sascha Dietrich, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 11–13.
https://doi.org/10.1182/blood-2020-136539
Published: 2020
Journal Articles

Baseline Biomarkers of T-Cell Function Correlate with Clinical Responses to Odronextamab (REGN1979), and Loss of CD20 Target Antigen Expression Identified As a Mechanism of Treatment Resistance

Jurriaan Brouwer-Visser, PhD, Nathalie Fiaschi, PhD, Raquel P. Deering, PhD, Ankur Dhanik, PhD, Kamil J. Cygan, PhD, Wen Zhang, PhD, Se Jeong, MPH, Stephane Pourpe, MS, Lauren Boucher, Sara Hamon, PhD, Max S. Topp, MD, Rajat Bannerji, MDPhD, Johannes Duell, MD, Ranjana Advani, MD, Dina M. Flink, PhD, Aafia Chaudhry, MD MBA, MS, Andres Sirulnik, MD PhD, Andrew J. Murphy, PhD, David M. Weinreich, MD, George D. Yancopoulos, MD PhD, Gavin Thurston, PhD, Srikanth R. Ambati, MBBS, MD, Vladimir Jankovic, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 10–11.
https://doi.org/10.1182/blood-2020-137499
Published: 2020