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Journal Articles

Venetoclax Plus High-Dose Cytarabine and Mitoxantrone As Feasible and Effective Novel Treatment for Relapsed AML: Results of the Phase-I SAL Relax Trial

Christoph Röllig, Lars Fransecky, Maher Hanoun, Björn Steffen, Sabrina Kraus, Christoph Schliemann, Annett Haake, Frank Fiebig, Sven Zukunft, Nael Alakel, Jan Moritz Middeke, Martin Bornhaeuser, Friedrich Stoelzel, Johannes Schetelig, Leo Ruhnke, Michael Kramer, Malte Von Bonin, Maximilian Alexander Röhnert, Uta Oelschlägel, Claudia D. Baldus, Hubert Serve, Martin Wermke
Journal: Blood
Blood (2022) 140 (Supplement 1): 3327–3328.
https://doi.org/10.1182/blood-2022-159897
Published: 2022
Journal Articles

In Patients with Relapsed/Refractory AML Sequential Conditioning and Immediate Allogeneic Stem Cell Transplantation (allo-HCT) Results in Similar Overall and Leukemia-Free Survival Compared to Intensive Remission Induction Chemotherapy Followed By Allo-HCT: Results from the Randomized Phase III ASAP Trial

Matthias Stelljes, Jan Moritz Middeke, Gesine Bug, Eva-Maria Wagner, Lutz Peter Mueller, Schmid Christoph, Stefan W. Krause, Wolfgang Bethge, Edgar Jost, Uwe Platzbecker, Stefan Klein, Jörg Schubert, Judith Niederland, Martin Kaufmann, Kerstin Schäfer-Eckart, Markus Schaich, Henning Baldauf, Friedrich Stölzel, Cathleen Petzold, Christoph Röllig, Nael Alakel, Björn Steffen, Beate Hauptrock, Christian Reicherts, Christoph Schliemann, Hubert Serve, Alexander H. Schmidt, Martin Bornhäuser, Jan-Henrik Mikesch, Johannes Schetelig
Journal: Blood
Blood (2022) 140 (Supplement 1): 9–11.
https://doi.org/10.1182/blood-2022-159962
Published: 2022
Journal Articles

Single Versus Double Induction with "7+3" Containing 60 Versus 90 Mg Daunorubicin for Newly Diagnosed AML: Results from the Randomized Controlled SAL Dauno-Double Trial

Christoph Röllig, Björn Steffen, Christoph Schliemann, Jan-Henrik Mikesch, Nael Alakel, Regina Herbst, Mathias Haenel, Richard Noppeney, Maher Hanoun, Martin Kaufmann, Zdenek Racil, Kerstin Schäfer-Eckart, Tim Sauer, Andreas Neubauer, Claudia D. Baldus, Jolana Mertova, Edgar Jost, Dirk Niemann, Jan Novak, Stefan W. Krause, Sebastian Scholl, Andreas Hochhaus, Gerhard Held, Tomáš Szotkowski, Christoph Schmid, Andreas Rank, Lars Fransecky, Michael Kramer, Frank Fiebig, Annett Haake, Friedrich Stoelzel, Johannes Schetelig, Jan Moritz Middeke, Uwe Platzbecker, Christian Thiede, Carsten Müller-Tidow, Wolfgang E. Berdel, Hubert Serve, Gerhard Ehninger, Jiří Mayer, Martin Bornhaeuser
Journal: Blood
Blood (2022) 140 (Supplement 1): 523–525.
https://doi.org/10.1182/blood-2022-157126
Published: 2022
Journal Articles

Inotuzumab Ozogamicin Induction Followed By Standard Chemotherapy Yields High Remission Rates and Promising Survival in Older (>55 Years) Patients with De Novo B-Lymphoblastic Leukemia (GMALL-Initial1 Trial)

Matthias Stelljes, Nael Alakel, Ralph Wäsch, Sebastian Scholl, Kathrin Nachtkamp, Andreas Rank, Mathias Haenel, Bernd Spriewald, Maher Hanoun, Sonja Martin, Katjana Schwab, Julian Knaden, Lena Reiser, Julia Marx, Klaus Wethmar, Tim Sauer, Wolfgang E. Berdel, Georg Lenz, Monika Brüggemann, Simon Raffel, Nicola Goekbuget
Journal: Blood
Blood (2022) 140 (Supplement 1): 510–512.
https://doi.org/10.1182/blood-2022-162235
Published: 2022
Journal Articles

Results of the Risk-Adapted, MRD-Stratified GMALL Trial 08/2013 in 281 T-ALL / T-Lbl Patients: Excellent Outcome of Standard Risk Thymic T-ALL

Nicola Goekbuget, Walter Fiedler, Nael Alakel, Max S. Topp, Maher Hanoun, Björn Steffen, Ralph Wäsch, Andreas Viardot, Kathrin Nachtkamp, Matthias Stelljes, Hendrik Poeck, Vladan Vucinic, Boris Böll, Joachim Beck, Lars Fransecky, Knut Wendelin, Folker Schneller, Christoph Faul, Veit L Buecklein, Lena Reiser, Monika Brüggemann, Hubert Serve, Stefan Schwartz
Journal: Blood
Blood (2022) 140 (Supplement 1): 115–117.
https://doi.org/10.1182/blood-2022-158381
Published: 2022
Journal Articles

Outcome of 841 Older Patients (>55 yrs) with Newly Diagnosed Ph/BCR-ABL Negative ALL Prospectively Treated According to Pediatric-Based, Age-Adapted GMALL Protocols

Nicola Goekbuget, Andreas Viardot, Björn Steffen, Joachim Hahn, Bernd Spriewald, Sonja Martin, Simon Raffel, Lino L. Teichmann, Arne Trummer, Winfried Alsdorf, Anke Morgner, Stefan Schwartz, Matthias Stelljes, Vladan Vucinic, Nael Alakel, Andrea Stoltefuß, Claudia D. Baldus, Monika Brüggemann, Hubert Serve, Dieter Hoelzer
Journal: Blood
Blood (2022) 140 (Supplement 1): 121–123.
https://doi.org/10.1182/blood-2022-158934
Published: 2022
Journal Articles

Real-World Experience of CPX-351 As First-Line Treatment in 188 Patients with Acute Myeloid Leukemia

Christina Rautenberg, Friedrich Stölzel, Christoph Röllig, Matthias Stelljes, Verena I Gaidzik, Michael Lauseker, Oliver Kriege, Mareike Verbeek, Julia M. Unglaub, Felicitas Thol, Stefan W. Krause, Mathias Haenel, Charlotte Neuerburg, Vladan Vucinic, Christian Jehn, Julia Severmann, Maxi Wass, Lars Fransecky, Jens Chemnitz, Udo Holtick, Kerstin Schäfer-Eckart, Josephine Schröder, Sabrina Kraus, William Hermann Krüger, Ulrich Kaiser, Sebastian Scholl, Lea Henning, Guido Kobbe, Rainer Haas, Nael Alakel, Maximilian Alexander Röhnert, Katja Sockel, Maher Hanoun, Uwe Platzbecker, Tobias A. W. Holderried, Anke Morgner, Michael Heuser, Tim Sauer, Katharina S. Goetze, Eva Maria Wagner, Konstanze Döhner, Hartmut Döhner, Christoph Schliemann, Johannes Schetelig, Martin Bornhäuser, Ulrich Germing, Thomas Schroeder, Moritz Moritz Middeke
Journal: Blood
Blood (2021) 138 (Supplement 1): 33.
https://doi.org/10.1182/blood-2021-153440
Published: 2021
Journal Articles

Allogeneic Hematopoietic Cell Transplantation in Patients ≤ 60 Years with Intermediate-Risk Acute Myeloid Leukemia in First Remission - Results of the Randomized Etal-1 Trial-

Martin Bornhaeuser, Christoph Schliemann, Johannes Schetelig, Christoph Rollig, Michael Kramer, Bertram Glass, Uwe Platzbecker, Andreas Burchert, Mathias Haenel, Lutz Peter Mueller, Stefan Klein, Gesine Bug, Dietrich W. Beelen, Wolf Roesler, Kerstin Schaefer-Eckart, Christoph Schmid, Edgar Jost, Georg Lenz, Johanna Tischer, Karsten Spiekermann, Markus Pfirrmann, Hubert Serve, Friedrich Stoelzel, Nael Alakel, Gerhard Ehninger, Wolfgang E. Berdel, Matthias Stelljes
Journal: Blood
Blood (2021) 138 (Supplement 1): 173.
https://doi.org/10.1182/blood-2021-145167
Published: 2021
Journal Articles

Gemtuzumab Ozogamicin Plus Midostaurin in Combination with Standard Intensive Induction Therapy in Newly Diagnosed AML: Results from a Phase-I Study

Christoph Röllig, Christoph Schliemann, Jan-Henrik Mikesch, Lars Fransecky, Claudia D. Baldus, Björn-Niklas Heydrich, Maher Hanoun, Richard Noppeney, Sebastian Scholl, Ulf Schnetzke, Kerstin Schäfer-Eckart, Knut Wendelin, Martin Wermke, Manja Reimann, Frank Fiebig, Theresa Kretschmann, Friedrich Stoelzel, Nael Alakel, Martin Bornhäuser
Journal: Blood
Blood (2021) 138 (Supplement 1): 2324.
https://doi.org/10.1182/blood-2021-150069
Published: 2021
Journal Articles

Final Induction Therapy Results of an Open Label Phase II Study Using Inotuzumab Ozogamicin for Induction Therapy, Followed By a Conventional Chemotherapy Based Consolidation and Maintenance Therapy in Patients Aged 56 Years and Older with Acute B-Lymphoblastic Leukemia (INITIAL-1 trial)

Matthias Stelljes, Nael Alakel, Ralph Wäsch, Sebastian Scholl, Kathrin Nachtkamp, Andreas Rank, Mathias Haenel, Bernd Spriewald, Maher Hanoun, Sonja Martin, Katjana Schwab, Julian Knaden, Julia Marx, Klaus Wethmar, Tim Sauer, Wolfgang E. Berdel, Georg Lenz, Martin Dugas, Nicola Goekbuget, Monika Brueggemann, Simon Raffel
Journal: Blood
Blood (2021) 138 (Supplement 1): 2300.
https://doi.org/10.1182/blood-2021-145553
Published: 2021
Journal Articles

First Results of the Risk-Adapted, MRD-Stratified GMALL Trial 08/2013 in 705 Adults with Newly Diagnosed Acute Lymphoblastic Leukemia/Lymphoma (ALL/LBL)

Nicola Goekbuget, Matthias Stelljes, Andreas Viardot, Kathrin Nachtkamp, Björn Steffen, Folker Schneller, Nael Alakel, Max Topp, Boris Böll, Christoph Faul, Karsten Spiekermann, Knut Wendelin, Maher Hanoun, Ralph Wäsch, Joachim Beck, Sonja Martin, Vladan Vucinic, Claudia D. Baldus, Monika Brüggemann, Thomas Burmeister, Heike Pfeifer, Stefan Schwartz, Lena Baumann, Diana Tichy, Hubert Serve, Walter Fiedler
Journal: Blood
Blood (2021) 138 (Supplement 1): 362.
https://doi.org/10.1182/blood-2021-146306
Published: 2021
Journal Articles

Interim Results of a Multicenter, Single-Arm Study to Assess Blinatumomab in Adult Patients (pts) with Minimal Residual Disease (MRD) of B-Precursor (BCP) Acute Lymphoblastic Leukemia (GMALL-MOLACT1-BLINA)

Nicola Goekbuget, MD, Wiba Keke Wermann, Stefan Schwartz, MD PhD, Andreas Hüttmann, MD, Christoph Faul, MD, Simon Raffel, MD, Andreas Viardot, Professor Dr, Walter Fiedler, MD, Nael Alakel, MD, Matthias Stelljes, MD, Marion Subklewe, MD, Ralph Wäsch, Sonja Martin, MD, Wolfram Jung, MD, Vladan Vucinic, MD, Mustafa Kondakci, MD, Lars R. Fransecky, MD, Daniela Heidenreich, MD, Knut Wendelin, MD, Julian Hermann, Hubert Serve, MD PhD, Ralf C Bargou, MD PhD, Max S. Topp, MD, Monika Brüggemann, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 39–40.
https://doi.org/10.1182/blood-2020-137350
Published: 2020
Journal Articles

Molecular Subgroups of T Cell Acute Lymphoblastic Leukemia in Adults Treated According to GMALL Protocols

Martin Neumann, Lorenz Bastian, Sonja Hänzelmann, Alina Hartmann, Heiko Trautmann, PhD, Jutta Ortiz Tanchez, Cornelia Schlee, Michael P Schroeder, PhD, Lars R. Fransecky, MD, Sebastian Vosberg, Walter Fiedler, MD, Nael Alakel, MD, Mustafa Kondakci, MD, Michael Starck, MD, Stefan Schwartz, MD PhD, Carsten Müller-Tidow, MD, Folker Schneller, Albert Reichle, Thomas Burmeister, Philipp A. Greif, MD PD, Monika Brüggemann, MD, Nicola Goekbuget, MD, Claudia D Baldus, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 37–38.
https://doi.org/10.1182/blood-2020-141921
Published: 2020
Journal Articles

First Results of an Open Label Phase II Study to Evaluate the Efficacy and Safety of Inotuzumab Ozogamicin for Induction Therapy Followed By a Conventional Chemotherapy Based Consolidation and Maintenance Therapy in Patients Aged 56 Years and Older with Acute Lymphoblastic Leukemia (INITIAL-1 trial)

Matthias Stelljes, MD, Simon Raffel, MD, Ralph Wäsch, Sebastian Scholl, Mustafa Kondakci, MD, Andreas Rank, PD Dr, Mathias Haenel, MD, Sonja Martin, MD, Katjana Schwab, MD, Julian Knaden, Klaus Wethmar, MD, Tim Sauer, MD, Wolfgang E. Berdel, Prof., MD, Georg Lenz, Martin Dugas, Monika Brüggemann, MD, Nicola Goekbuget, MD, Nael Alakel, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 12–13.
https://doi.org/10.1182/blood-2020-136920
Published: 2020
Journal Articles

Remission and Survival after Single Versus Double Induction with 7+3 for Newly Diagnosed Acute Myeloid Leukemia: Results from the Planned Interim Analysis of Randomized Controlled SAL-Daunodouble Trial

Christoph Röllig, MD MSC, Björn Steffen, MD, Nael Alakel, MD, Regina Herbst, MD, Richard Noppeney, MD, Maher Hanoun, MD PhD, Zdenek Racil, MD PhD, Kerstin Schäfer-Eckart, MD, Alwin Krämer, MD, Andreas Neubauer, Professor Dr, Claudia D Baldus, MD, Christoph Schliemann, Prof., MD, Martin Kaufmann, MD, Jolana Mertova, Edgar Jost, Dirk Niemann, MD, Jan Novak, Stefan W Krause, Sebastian Scholl, Gerhard Held, Professor Dr, Stefani B. Parmentier, Tomáš Szotkowski, MD PhD, Pavel Zak, MD, Andreas Rank, PD Dr, Maxi Wass, MD, Sebastian Buske, Michael Kramer, Frank Fiebig, Annett Haake, Johannes Schetelig, MDMSc, Uwe Platzbecker, Christian Thiede, MD, Carsten Müller-Tidow, MD, Wolfgang E. Berdel, Prof., MD, Hubert Serve, MD PhD, Gerhard Ehninger, MD, Jiri Mayer, Martin Bornhäuser, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 1–3.
https://doi.org/10.1182/blood-2020-140246
Published: 2020
Journal Articles

Comorbidities Are Frequent in Older Patients with De Novo Acute Lymphoblastic Leukemia (ALL) and Correlate with Induction Mortality: Analysis of More Than 1200 Patients from GMALL Data Bases

Wiba Keke Wermann, Andreas Viardot, MD, Sabine Kayser, MD, Nael Alakel, MD, Ahmet Elmaagacli, Christoph Faul, MD, Walter Fiedler, MD, Heinz A. Horst, MD, Elisabeth Lange, Sonja Martin, MD, Omar Mohamed, MD, Anke Morgner, MD, Albrecht Reichle, MD, Karsten Spiekermann, MD, Bernd Spriewald, MD, Michael Starck, MD, Matthias Stelljes, MD, Arne Trummer, Vladan Vucinic, MD, Hubert Serve, MD, Dieter Hoelzer, MD PhD, Nicola Goekbuget, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 660.
https://doi.org/10.1182/blood-2018-99-111954
Published: 2018
Journal Articles

Evaluation of Various Strategies to Generate NPM1mut-Specific T Cell Clones

Elke Ruecker-Braun, PhD, Falk Heidenreich, PhD, Cornelia S Link, MD, Maria Schmiedgen, BSc, Rebekka Wehner, PhD, Denise Kühn, BSc, Katharina Heidrich, MD, Nael Alakel, MD, Marc Schmitz, PhD, Christian Thiede, MD, Gerhard Ehninger, MD, Martin Bornhäuser, MD, Johannes Schetelig, MD MSc
Journal: Blood
Blood (2016) 128 (22): 5718.
https://doi.org/10.1182/blood.V128.22.5718.5718
Published: 2016
Journal Articles

Long Term Follow up and Impact of Comorbidity Prior to Allogeneic Hematopoietic Stem Cell Transplantation in Patients with Relapsed or Refractory AML - Lessons Learned from the Prospective Bridge Trial -

Jan Moritz Middeke, MD, Regina Herbst, MD, Stefani Barbara Parmentier, MD, Gesine Bug, MD, Mathias Hänel, MD, Gernot Stuhler, Kerstin Schäfer-Eckart, MD, Wolf Rösler, MD, Stefan A. Klein, MD, Wolfgang Bethge, MD, Nael Alakel, MD, Markus Schaich, MD, Anke Morgner, MD, Michael Kramer, MSc, Katja Sockel, MD, Malte von Bonin, MD, Friedrich Stölzel, MD, Uwe Platzbecker, MD, Christoph Röllig, MD, Christian Thiede, MD, Gerhard Ehninger, MD, Martin Bornhäuser, MD, Johannes Schetelig, MD MSc
Journal: Blood
Blood (2016) 128 (22): 4692.
https://doi.org/10.1182/blood.V128.22.4692.4692
Published: 2016
Journal Articles

The Prevalence of Extramedullary AML Detected By 18-FDG/PET-CT: Results from the Prospective PET-AML Trial

Friedrich Stölzel, MD, Tors Lüer, Stefani B Parmentier, MD, Tobias Paulus, MD, Friederike Kuithan, MD, Michael Kramer, PhD, Nael Alakel, MD, Katja Sockel, MD, Franziska Taube, MD, Jörg Kotzerke, Christoph Röllig, MD, Martin Bornhäuser, MD, Gerhard Ehninger, MD, Klaus Zoephel, MD, Markus Schaich, MD
Journal: Blood
Blood (2014) 124 (21): 2270.
https://doi.org/10.1182/blood.V124.21.2270.2270
Published: 2014
Journal Articles

– Updated Results from the Bridge Trial: Long-Term Survival and Impact of Donor Availability – Clofarabine Salvage Therapy Prior to Allogeneic Hematopoietic Stem Cell Transplantation in Patients with Relapsed or Refractory AML

Jan Moritz Middeke, MD, Regina Herbst, MD, Stefani B Parmentier, MD, Gesine Bug, MD, Mathias Hänel, MD, Gernot Stuhler, MD, Kerstin Schäfer-Eckart, MD, Wolf Rösler, MD, Stefan A. Klein, Wolfgang Bethge, MD, Ulrich Bitz, MD, Nael Alakel, MD, Markus Schaich, MD, Anke Morgner, MD, Michael Kramer, PhD, Uwe Platzbecker, MD, Christoph Röllig, MD, Christian Thiede, MD, Gerhard Ehninger, MD, Martin Bornhäuser, MD, Johannes Schetelig, MD M. Sc,
Journal: Blood
Blood (2014) 124 (21): 1204.
https://doi.org/10.1182/blood.V124.21.1204.1204
Published: 2014