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Journal Articles

Epigenetic control over the cell-intrinsic immune response antagonizes self-renewal in acute myeloid leukemia

Blood (2024) 143 (22): 2284–2299.

https://doi.org/10.1182/blood.2023021640

Published: 2024

Includes: Supplemental data

Journal Articles

Germ line variant GFI1-36N affects DNA repair and sensitizes AML cells to DNA damage and repair therapy

Daria Frank, Pradeep Kumar Patnana, Jan Vorwerk, Lianghao Mao, Lavanya Mokada Gopal, Noelle Jung, Thorben Hennig, Leo Ruhnke, Joris Maximillian Frenz, Maithreyan Kuppusamy, Robert Autry, Lanying Wei, Kaiyan Sun, Helal Mohammed Mohammed Ahmed, Axel Künstner, Hauke Busch, Heiko Müller, Stephan Hutter, Gregor Hoermann, Longlong Liu, Xiaoqing Xie, Yahya Al-Matary, Subbaiah Chary Nimmagadda, Fiorella Charles Cano, Michael Heuser, Felicitas Thol, Gudrun Göhring, Doris Steinemann, Jürgen Thomale, Theo Leitner, Anja Fischer, Roland Rad, Christoph Röllig, Heidi Altmann, Desiree Kunadt, Wolfgang E. Berdel, Jana Hüve, Felix Neumann, Jürgen Klingauf, Virginie Calderon, Bertram Opalka, Ulrich Dührsen, Frank Rosenbauer, Martin Dugas, Julian Varghese, Hans Christian Reinhardt, Nikolas von Bubnoff, Tarik Möröy, Georg Lenz, Aarif M. N. Batcha, Marianna Giorgi, Murugan Selvam, Eunice Wang, Shannon K. McWeeney, Jeffrey W. Tyner, Friedrich Stölzel, Matthias Mann, Ashok Kumar Jayavelu, Cyrus Khandanpour

Blood (2023) 142 (25): 2175–2191.

https://doi.org/10.1182/blood.2022015752

Published: 2023

Includes: Supplemental data

Journal Articles

High-Hyperdiploid Acute Lymphoblastic Leukemia in Children with LZTR1 Germline Variants

Triantafyllia Brozou, Arndt Borkhardt, Ute Fischer, Danielle Brandes, Layal Yasin, Oskar A. Haas, Stefanie Junk, Martin Stanulla, Ammarah Anwar, Stavrieta Soura, Julia Hauer, Franziska Auer, Martin Dugas, Carolin Walter, Julian Varghese, Tobias Reiff, Lisa Zipper, Anna Emilia Hoffmann, Rabea Wagener

Blood (2023) 142 (Supplement 1): 1408.

https://doi.org/10.1182/blood-2023-174500

Published: 2023

Journal Articles

Somatic Mutations and DNA Hypermethylation at Enhancers and Promoters Identify Distinct Subtypes within Lower-Risk Myelodysplastic Syndromes

Blood (2023) 142 (Supplement 1): 4587.

https://doi.org/10.1182/blood-2023-180071

Published: 2023

Journal Articles

Final Induction Therapy Results of an Open Label Phase II Study Using Inotuzumab Ozogamicin for Induction Therapy, Followed By a Conventional Chemotherapy Based Consolidation and Maintenance Therapy in Patients Aged 56 Years and Older with Acute B-Lymphoblastic Leukemia (INITIAL-1 trial)

Blood (2021) 138 (Supplement 1): 2300.

https://doi.org/10.1182/blood-2021-145553

Published: 2021

Journal Articles

Novel Germline POT1 Variant Predisposes to Childhood Acute Myeloid Leukemia

Pia Michler, Franziska Auer, Rabea Wagener, Triantafyllia Brozou, Ulrike Anne Friedrich, Carolin Walter, Martin Dugas, Arndt Borkhardt, Friedrich Stölzel, Julia Hauer

Blood (2021) 138 (Supplement 1): 3449.

https://doi.org/10.1182/blood-2021-150456

Published: 2021

Journal Articles

Clonal Evolution at First Sight: A Combined Visualization of Diverse Diagnostic Methods Improves Understanding of Leukemia Progression

Sarah Sandmann, Yvonne Lisa Behrens, Felicitas Thol, Michael Heuser, Doris Steinemann, Martin Dugas, Brigitte Schlegelberger, Gudrun Gohring

Blood (2021) 138 (Supplement 1): 1293.

https://doi.org/10.1182/blood-2021-147187

Published: 2021

Journal Articles

Validation of the Qualms Questionnaire to Assess Health-Related Quality of Life in European and Israeli Patients with Myelodysplastic Syndromes: Results from the MDS-Right Project

Fabio Efficace, Karin A Koinig, Francesco Cottone, David Bowen, Moshe Mittelman, Saskia M. C. Langemeijer, Dominic Culligan, Kalman Filanovsky, Gregory A. Abel, Michael Storck, Alexandra Smith, Corine Van Marrewijk, Martin Dugas, Theo M de Witte, Reinhard Stauder

Blood (2021) 138 (Supplement 1): 1982.

https://doi.org/10.1182/blood-2021-147176

Published: 2021

Journal Articles

Recurrent Germline Variant in the Cohesin Complex Gene RAD21 Predisposes Children to Lymphoblastic Leukemia and Lymphoma

Blood (2021) 138 (Supplement 1): 3358.

https://doi.org/10.1182/blood-2021-150284

Published: 2021

Journal Articles

Integrative genomic analysis of pediatric T-cell lymphoblastic lymphoma reveals candidates of clinical significance

Blood (2021) 137 (17): 2347–2359.

https://doi.org/10.1182/blood.2020005381

Published: 2021

Includes: Supplemental data

Journal Articles

First Results of an Open Label Phase II Study to Evaluate the Efficacy and Safety of Inotuzumab Ozogamicin for Induction Therapy Followed By a Conventional Chemotherapy Based Consolidation and Maintenance Therapy in Patients Aged 56 Years and Older with Acute Lymphoblastic Leukemia (INITIAL-1 trial)

Matthias Stelljes, MD, Simon Raffel, MD, Ralph Wäsch, Sebastian Scholl, Mustafa Kondakci, MD, Andreas Rank, PD Dr, Mathias Haenel, MD, Sonja Martin, MD, Katjana Schwab, MD, Julian Knaden, Klaus Wethmar, MD, Tim Sauer, MD, Wolfgang E. Berdel, Prof., MD, Georg Lenz, Martin Dugas, Monika Brüggemann, MD, Nicola Goekbuget, MD, Nael Alakel, MD

Blood (2020) 136 (Supplement 1): 12–13.

https://doi.org/10.1182/blood-2020-136920

Published: 2020

Journal Articles

Mutation Profiles Identify Distinct Clusters of Lower Risk Myelodysplastic Syndromes with Unique Clinical and Biological Features and Clinical Endpoints

Blood (2020) 136 (Supplement 1): 29.

https://doi.org/10.1182/blood-2020-138549

Published: 2020

Journal Articles

Site-specific methylation of 18S ribosomal RNA by SNORD42A is required for acute myeloid leukemia cell proliferation

Cornelius Pauli, Yi Liu, Christian Rohde, Chunhong Cui, Daria Fijalkowska, Dennis Gerloff, Carolin Walter, Jeroen Krijgsveld, Martin Dugas, Bayram Edemir, Caroline Pabst, Lutz P. Müller, Fengbiao Zhou, Carsten Müller-Tidow

Blood (2020) 135 (23): 2059–2070.

https://doi.org/10.1182/blood.2019004121

Published: 2020

Includes: Supplemental data

Journal Articles

Temporal autoregulation during human PU.1 locus SubTAD formation

Daniel Schuetzmann, Carolin Walter, Boet van Riel, Sabrina Kruse, Thorsten König, Tabea Erdmann, Alexander Tönges, Eric Bindels, Andre Weilemann, Claudia Gebhard, Klaus Wethmar, Chiara Perrod, Julia Minderjahn, Michael Rehli, Ruud Delwel, Georg Lenz, Stefan Gröschel, Martin Dugas, Frank Rosenbauer

Blood (2018) 132 (25): 2643–2655.

https://doi.org/10.1182/blood-2018-02-834721

Published: 2018

Includes: Supplemental data

Journal Articles

Increased DNA methylation of Dnmt3b targets impairs leukemogenesis

Isabell Schulze, Christian Rohde, Marina Scheller-Wendorff, Nicole Bäumer, Annika Krause, Friederike Herbst, Pia Riemke, Katja Hebestreit, Petra Tschanter, Qiong Lin, Heinz Linhart, Lucy A. Godley, Hanno Glimm, Martin Dugas, Wolfgang Wagner, Wolfgang E. Berdel, Frank Rosenbauer, Carsten Müller-Tidow

Blood (2016) 127 (12): 1575–1586.

https://doi.org/10.1182/blood-2015-07-655928

Published: 2016

Includes: Supplemental data

Journal Articles

A New ETV6-RUNX1 In Vivo Model Produces a Phenocopy of the Human Pb-ALL

Blood (2015) 126 (23): 3658.

https://doi.org/10.1182/blood.V126.23.3658.3658

Published: 2015

Journal Articles

Two Novel Distinct Subtypes of Myeloid Neoplasms Molecularly Associated with Histone H3K36 Methylations

Blood (2015) 126 (23): 2841.

https://doi.org/10.1182/blood.V126.23.2841.2841

Published: 2015

Journal Articles

DDX41 Is a Tumor Suppressor Gene Associated with Inherited and Acquired Mutations

Blood (2014) 124 (21): 125.

https://doi.org/10.1182/blood.V124.21.125.125

Published: 2014

Journal Articles

Azacitidine Followed By Intensive Induction/Consolidation Chemotherapy in Older Patients with Acute Myeloid Leukemia (AML): Results from the Randomized AML-AZA Trial of the Study Alliance Leukemias (SAL)

Carsten Müller-Tidow, MD, Petra Tschanter, MD, Utz Krug, MD, Stefanie Goellner, PhD, Christoph Röllig, MD, Christian Thiede, MD, Anja Koschmieder, Martin Dugas, PhD, Joachim Gerss, PhD, Trude Butterfaß-Bahloul, Ruth Wagner, Stefan W. Krause, MD, Ulrich Kaiser, Volker Kunzmann, MD, Björn Steffen, MD, Richard Noppeney, MD, Wolfgang Herr, MD, Claudia D Baldus, Norbert Schmitz, MD, Katharina Götze, Albrecht Reichle, Martin Kaufmann, MD, Andreas Neubauer, MD, Kerstin Schäfer-Eckart, MD, Mathias Hänel, MD, Rudolf Peceny, MD, Haack Bea, Lilly Meredith, Norbert Frickhofen, MD, Michael G Kiehl, MD, Aristoteles A.N. Giagounidis, MD PhD, Martin Görner, Roland Repp, MD, Ralph Naumann, MD, Hartmut Link, MDPhD, Alexander Kiani, MD, Steffen Koschmieder, MD, Tim H. Brümmendorf, MD, Hubert Serve, MD, Gerhard Ehninger, MD, Wolfgang E Berdel, MD

Blood (2014) 124 (21): 946.

https://doi.org/10.1182/blood.V124.21.946.946

Published: 2014

Journal Articles

Mutations in the cohesin complex in acute myeloid leukemia: clinical and prognostic implications

Blood (2014) 123 (6): 914–920.

https://doi.org/10.1182/blood-2013-07-518746

Published: 2014

Includes: Supplemental data

NARROW

Epigenetic control over the cell-intrinsic immune response antagonizes self-renewal in acute myeloid leukemia

Germ line variant GFI1-36N affects DNA repair and sensitizes AML cells to DNA damage and repair therapy

High-Hyperdiploid Acute Lymphoblastic Leukemia in Children with LZTR1 Germline Variants

Somatic Mutations and DNA Hypermethylation at Enhancers and Promoters Identify Distinct Subtypes within Lower-Risk Myelodysplastic Syndromes

Final Induction Therapy Results of an Open Label Phase II Study Using Inotuzumab Ozogamicin for Induction Therapy, Followed By a Conventional Chemotherapy Based Consolidation and Maintenance Therapy in Patients Aged 56 Years and Older with Acute B-Lymphoblastic Leukemia (INITIAL-1 trial)

Novel Germline POT1 Variant Predisposes to Childhood Acute Myeloid Leukemia

Clonal Evolution at First Sight: A Combined Visualization of Diverse Diagnostic Methods Improves Understanding of Leukemia Progression

Validation of the Qualms Questionnaire to Assess Health-Related Quality of Life in European and Israeli Patients with Myelodysplastic Syndromes: Results from the MDS-Right Project

Recurrent Germline Variant in the Cohesin Complex Gene RAD21 Predisposes Children to Lymphoblastic Leukemia and Lymphoma

Integrative genomic analysis of pediatric T-cell lymphoblastic lymphoma reveals candidates of clinical significance

First Results of an Open Label Phase II Study to Evaluate the Efficacy and Safety of Inotuzumab Ozogamicin for Induction Therapy Followed By a Conventional Chemotherapy Based Consolidation and Maintenance Therapy in Patients Aged 56 Years and Older with Acute Lymphoblastic Leukemia (INITIAL-1 trial)

Mutation Profiles Identify Distinct Clusters of Lower Risk Myelodysplastic Syndromes with Unique Clinical and Biological Features and Clinical Endpoints

Site-specific methylation of 18S ribosomal RNA by SNORD42A is required for acute myeloid leukemia cell proliferation

Temporal autoregulation during human PU.1 locus SubTAD formation

Increased DNA methylation of Dnmt3b targets impairs leukemogenesis

A New ETV6-RUNX1 In Vivo Model Produces a Phenocopy of the Human Pb-ALL

Two Novel Distinct Subtypes of Myeloid Neoplasms Molecularly Associated with Histone H3K36 Methylations

DDX41 Is a Tumor Suppressor Gene Associated with Inherited and Acquired Mutations

Azacitidine Followed By Intensive Induction/Consolidation Chemotherapy in Older Patients with Acute Myeloid Leukemia (AML): Results from the Randomized AML-AZA Trial of the Study Alliance Leukemias (SAL)

Mutations in the cohesin complex in acute myeloid leukemia: clinical and prognostic implications

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American Society of Hematology

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American Society of Hematology

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