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Journal Articles

ATM germ line pathogenic variants affect outcomes in children with ataxia-telangiectasia and hematological malignancies

Sarah Elitzur, Ruth Shiloh, Jan L. C. Loeffen, Agata Pastorczak, Masatoshi Takagi, Simon Bomken, Andre Baruchel, Thomas Lehrnbecher, Sarah K. Tasian, Oussama Abla, Nira Arad-Cohen, Itziar Astigarraga, Miriam Ben-Harosh, Nicole Bodmer, Triantafyllia Brozou, Francesco Ceppi, Liliia Chugaeva, Luciano Dalla Pozza, Stephane Ducassou, Gabriele Escherich, Roula Farah, Amber Gibson, Henrik Hasle, Julieta Hoveyan, Elad Jacoby, Janez Jazbec, Stefanie Junk, Alexandra Kolenova, Jelena Lazic, Luca Lo Nigro, Nizar Mahlaoui, Lane Miller, Vassilios Papadakis, Lucie Pecheux, Marta Pillon, Ifat Sarouk, Jan Stary, Eftichia Stiakaki, Marion Strullu, Thai Hoa Tran, Marek Ussowicz, Jaime Verdu-Amoros, Anna Wakulinska, Joanna Zawitkowska, Dominique Stoppa-Lyonnet, A. Malcolm Taylor, Yosef Shiloh, Shai Izraeli, Veronique Minard-Colin, Kjeld Schmiegelow, Ronit Nirel, Andishe Attarbaschi, Arndt Borkhardt

Blood (2024) 144 (11): 1193–1205.

https://doi.org/10.1182/blood.2024024283

Published: 2024

Includes: Supplemental data

Journal Articles

CNS Invasion of TCF3::PBX1 + Leukemia Cells Requires Upregulation of AP-1 Signaling As Revealed By Brain Organoid Model

Philip Gebing, Stefanos Loizou, Sebastian Hänsch, Julian Schliehe-Diecks, Lea Spory, Pawel Stachura, Aleksandra Pandyra, Martin Schrappe, Gunnar Cario, Ameera Alsadeq, Denis Martin Schewe, Arndt Borkhardt, Lennart Lenk, Ute Fischer, Sanil Bhatia

Blood (2023) 142 (Supplement 1): 1407.

https://doi.org/10.1182/blood-2023-178613

Published: 2023

Journal Articles

Somatic and Germline Cohesin Genes Alterations in Pediatric Acute Lymphoblastic Leukemia

Blood (2023) 142 (Supplement 1): 1600.

https://doi.org/10.1182/blood-2023-189244

Published: 2023

Journal Articles

ATM Germline Pathogenic Variants Affect Treatment Outcomes in Children with Acute Lymphoblastic Leukemia/Lymphoma and Ataxia Telangiectasia

Sarah Elitzur, Ruth Shiloh, Jan Loeffen, Agata Pastorczak, Masatoshi Takagi, Simon Bomken, Andre Baruchel, Stephane Ducassou, Nizar Mahlaoui, Marion Strullu, Thomas Lehrnbecher, Kjeld Schmiegelow, Oussama Abla, Liliia Anderzhanova, Nira Arad-Cohen, Itziar Astigarraga, Miriam Ben-Harosh, Francesco Ceppi, Nicole Bodmer, Triantafyllia Brozou, Luciano Dalla-Pozza, Gabriele Escherich, Roula Farah, Amber Gibson, Henrik Hasle, Julieta Hoveyan, Elad Jacoby, Janez Jazbec, Alexandra Kolenova, Jelena Lazic, Luca Lo Nigro, Lane Miller, Vassilios Papadakis, Lucie Pecheux, Marta Pillon, Ifat Sarouk, Jan Stary, Eftichia Stiakaki, Sarah K. Tasian, Thai Hoa Tran, Marek Ussowicz, Jose Jaime Verdu-Amoros, Anna Wakulinska, Joanna Zawitkowska, Dominique Stoppa-Lyonnet, Malcolm Taylor, Yosef Shiloh, Shai Izraeli, Ronit Nirel, Veronique Minard-Colin, Andishe Attarbaschi, Arndt Borkhardt

Blood (2023) 142 (Supplement 1): 520.

https://doi.org/10.1182/blood-2023-179333

Published: 2023

Journal Articles

High-Hyperdiploid Acute Lymphoblastic Leukemia in Children with LZTR1 Germline Variants

Triantafyllia Brozou, Arndt Borkhardt, Ute Fischer, Danielle Brandes, Layal Yasin, Oskar A. Haas, Stefanie Junk, Martin Stanulla, Ammarah Anwar, Stavrieta Soura, Julia Hauer, Franziska Auer, Martin Dugas, Carolin Walter, Julian Varghese, Tobias Reiff, Lisa Zipper, Anna Emilia Hoffmann, Rabea Wagener

Blood (2023) 142 (Supplement 1): 1408.

https://doi.org/10.1182/blood-2023-174500

Published: 2023

Journal Articles

Pax5 Heterozygosity Affects B-Cell Differentiation and Generates a Deregulated Precursor Population in the Bone Marrow

Franziska Auer, Mina Morcos, Mikko Sipola, Sanni Moisio, Anna Viitasalo, Aleksandra Pandyra, Arndt Borkhardt, Merja Heinäniemi, Julia Hauer

Blood (2023) 142 (Supplement 1): 2768.

https://doi.org/10.1182/blood-2023-184384

Published: 2023

Journal Articles

EBV-driven lymphoid neoplasms associated with pediatric ALL maintenance therapy

Blood (2023) 141 (7): 743–755.

https://doi.org/10.1182/blood.2022016975

Published: 2023

Includes: Supplemental data

Journal Articles

Familial Predisposition to B-Cell Precursor Acute Lymphoblastic Leukemia Mediated By PAX5 Germline Variants

Franziska Auer, Adela Escuerdo, Ulrike Anne Friedrich, Polina Stepensky, Arndt Borkhardt, Sarah Elitzur, Masatoshi Takagi, Julia Hauer

Blood (2022) 140 (Supplement 1): 8888–8889.

https://doi.org/10.1182/blood-2022-166646

Published: 2022

Journal Articles

The Role of Adult Cancer Predisposition Genes in Hematological Malignancies of Childhood

Triantafyllia Brozou, Rabea Wagener, Danielle Brandes, Ute Fischer, Arndt Borkhardt

Blood (2022) 140 (Supplement 1): 8750–8751.

https://doi.org/10.1182/blood-2022-159655

Published: 2022

Journal Articles

A Human iPSC Model Reveals Specific Upregulation of Linker Histone H1-0 in ETV6::RUNX1 + Preleukemia and B Cell Precursor Acute Lymphoblastic Leukemia

Vera H Jepsen, Daniel Hein, Daniel Picard, Tobias Lautwein, Rabea Wagener, Nan Qin, Annika Filip, Merja Heinäniemi, Arndt Borkhardt, Ute Fischer

Blood (2022) 140 (Supplement 1): 3469–3470.

https://doi.org/10.1182/blood-2022-163564

Published: 2022

Journal Articles

Targeting Hyperactivated Lck in PAX5 Rearranged Pediatric B-Cell Precursors Acute Lymphoblastic Leukemia

Grazia Fazio, Manuel Quadri, Silvia Bresolin, Chiara Palmi, Michela Bardini, Athanasios Oikonomou, Jia-Wey Tu, Katerina Scharov, Alberto Peloso, Titus Watrin, Sanil Bhatia, Arndt Borkhardt, Andrea Biondi, Giovanni Cazzaniga

Blood (2022) 140 (Supplement 1): 3107–3108.

https://doi.org/10.1182/blood-2022-169023

Published: 2022

Journal Articles

Novel Drugs to Target JAK2 Rearrangements in Pediatric Acute Lymphoblastic Leukemia

Manuel Quadri, Claudia Saitta, Sonia Palamini, Chiara Palmi, Jia-Wey Tu, Sanil Bhatia, Arndt Borkhardt, Andrea Biondi, Giovanni Cazzaniga, Grazia Fazio

Blood (2022) 140 (Supplement 1): 364–365.

https://doi.org/10.1182/blood-2022-169437

Published: 2022

Journal Articles

Deciphering the Somatic and Germline Structural Variation Landscape in Pediatric B-Cell Precursor Acute Lymphoblastic Leukemia By Whole Genome Optical Mapping

Danielle Brandes, Triantafyllia Brozou, Karin Nebral, Anke K. Bergmann, Oskar A. Haas, Stefan Köhrer, Martin Stanulla, Ute Fischer, Arndt Borkhardt, Rabea Wagener

Blood (2022) 140 (Supplement 1): 9203–9204.

https://doi.org/10.1182/blood-2022-163110

Published: 2022

Journal Articles

Ph-like and IKZF1plus Features in Children with Down Syndrome and B Cell Precursor Acute Lymphoblastic Leukemia

Blood (2022) 140 (Supplement 1): 6367–6368.

https://doi.org/10.1182/blood-2022-169131

Published: 2022

Journal Articles

Pax5 Heterozygosity Delays BCR Expression in Preb-II Cells and Generates a Preleukemic Population

Franziska Auer, Juha Mehtonen, Mikko Sipola, Mina Morcos, Aleksandra Pandyra, Arndt Borkhardt, Merja Heinäniemi, Julia Hauer

Blood (2021) 138 (Supplement 1): 1140.

https://doi.org/10.1182/blood-2021-150144

Published: 2021

Journal Articles

Novel Germline POT1 Variant Predisposes to Childhood Acute Myeloid Leukemia

Pia Michler, Franziska Auer, Rabea Wagener, Triantafyllia Brozou, Ulrike Anne Friedrich, Carolin Walter, Martin Dugas, Arndt Borkhardt, Friedrich Stölzel, Julia Hauer

Blood (2021) 138 (Supplement 1): 3449.

https://doi.org/10.1182/blood-2021-150456

Published: 2021

Journal Articles

Recurrent Germline Variant in the Cohesin Complex Gene RAD21 Predisposes Children to Lymphoblastic Leukemia and Lymphoma

Blood (2021) 138 (Supplement 1): 3358.

https://doi.org/10.1182/blood-2021-150284

Published: 2021

Journal Articles

Toward prevention of childhood ALL by early-life immune training

Julia Hauer, Ute Fischer, Arndt Borkhardt

Blood (2021) 138 (16): 1412–1428.

https://doi.org/10.1182/blood.2020009895

Published: 2021

Journal Articles

NF1 Tumor Suppressor Gene Inactivation in Juvenile Myelomonocytic Leukemia: New Genetic Evidence and Consequences for Diagnostic Work-up

Blood (2020) 136 (Supplement 1): 30–31.

https://doi.org/10.1182/blood-2020-136294

Published: 2020

Journal Articles

An intact gut microbiome protects genetically predisposed mice against leukemia

Blood (2020) 136 (18): 2003–2017.

https://doi.org/10.1182/blood.2019004381

Published: 2020

Includes: Supplemental data

NARROW

ATM germ line pathogenic variants affect outcomes in children with ataxia-telangiectasia and hematological malignancies

CNS Invasion of TCF3::PBX1 + Leukemia Cells Requires Upregulation of AP-1 Signaling As Revealed By Brain Organoid Model

Somatic and Germline Cohesin Genes Alterations in Pediatric Acute Lymphoblastic Leukemia

ATM Germline Pathogenic Variants Affect Treatment Outcomes in Children with Acute Lymphoblastic Leukemia/Lymphoma and Ataxia Telangiectasia

High-Hyperdiploid Acute Lymphoblastic Leukemia in Children with LZTR1 Germline Variants

Pax5 Heterozygosity Affects B-Cell Differentiation and Generates a Deregulated Precursor Population in the Bone Marrow

EBV-driven lymphoid neoplasms associated with pediatric ALL maintenance therapy

Familial Predisposition to B-Cell Precursor Acute Lymphoblastic Leukemia Mediated By PAX5 Germline Variants

The Role of Adult Cancer Predisposition Genes in Hematological Malignancies of Childhood

A Human iPSC Model Reveals Specific Upregulation of Linker Histone H1-0 in ETV6::RUNX1 + Preleukemia and B Cell Precursor Acute Lymphoblastic Leukemia

Targeting Hyperactivated Lck in PAX5 Rearranged Pediatric B-Cell Precursors Acute Lymphoblastic Leukemia

Novel Drugs to Target JAK2 Rearrangements in Pediatric Acute Lymphoblastic Leukemia

Deciphering the Somatic and Germline Structural Variation Landscape in Pediatric B-Cell Precursor Acute Lymphoblastic Leukemia By Whole Genome Optical Mapping

Ph-like and IKZF1plus Features in Children with Down Syndrome and B Cell Precursor Acute Lymphoblastic Leukemia

Pax5 Heterozygosity Delays BCR Expression in Preb-II Cells and Generates a Preleukemic Population

Novel Germline POT1 Variant Predisposes to Childhood Acute Myeloid Leukemia

Recurrent Germline Variant in the Cohesin Complex Gene RAD21 Predisposes Children to Lymphoblastic Leukemia and Lymphoma

Toward prevention of childhood ALL by early-life immune training

NF1 Tumor Suppressor Gene Inactivation in Juvenile Myelomonocytic Leukemia: New Genetic Evidence and Consequences for Diagnostic Work-up

An intact gut microbiome protects genetically predisposed mice against leukemia

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American Society of Hematology

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ASH Publications

American Society of Hematology

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