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Journal Articles

Comparing malignant monocytosis across the updated WHO and ICC classifications of 2022

Francis Baumgartner, Constance Baer, Stefanos Bamopoulos, Edward Ayoub, Marietta Truger, Manja Meggendorfer, Miriam Lenk, Gregor Hoermann, Stephan Hutter, Heiko Müller, Wencke Walter, Martha-Lena Müller, Niroshan Nadarajah, Piers Blombery, Ulrich Keller, Wolfgang Kern, Claudia Haferlach, Torsten Haferlach

Blood (2024) 143 (12): 1139–1156.

https://doi.org/10.1182/blood.2023021199

Published: 2024

Includes: Supplemental data

Journal Articles

Germ line variant GFI1-36N affects DNA repair and sensitizes AML cells to DNA damage and repair therapy

Daria Frank, Pradeep Kumar Patnana, Jan Vorwerk, Lianghao Mao, Lavanya Mokada Gopal, Noelle Jung, Thorben Hennig, Leo Ruhnke, Joris Maximillian Frenz, Maithreyan Kuppusamy, Robert Autry, Lanying Wei, Kaiyan Sun, Helal Mohammed Mohammed Ahmed, Axel Künstner, Hauke Busch, Heiko Müller, Stephan Hutter, Gregor Hoermann, Longlong Liu, Xiaoqing Xie, Yahya Al-Matary, Subbaiah Chary Nimmagadda, Fiorella Charles Cano, Michael Heuser, Felicitas Thol, Gudrun Göhring, Doris Steinemann, Jürgen Thomale, Theo Leitner, Anja Fischer, Roland Rad, Christoph Röllig, Heidi Altmann, Desiree Kunadt, Wolfgang E. Berdel, Jana Hüve, Felix Neumann, Jürgen Klingauf, Virginie Calderon, Bertram Opalka, Ulrich Dührsen, Frank Rosenbauer, Martin Dugas, Julian Varghese, Hans Christian Reinhardt, Nikolas von Bubnoff, Tarik Möröy, Georg Lenz, Aarif M. N. Batcha, Marianna Giorgi, Murugan Selvam, Eunice Wang, Shannon K. McWeeney, Jeffrey W. Tyner, Friedrich Stölzel, Matthias Mann, Ashok Kumar Jayavelu, Cyrus Khandanpour

Blood (2023) 142 (25): 2175–2191.

https://doi.org/10.1182/blood.2022015752

Published: 2023

Includes: Supplemental data

Journal Articles

Whole Genome and Transcriptome Sequencing of 21 Paired Chronic and Blast Phase CML Cases: Acquisition of Genomic Alterations, Changes in the Transcriptomic Profiles and Occurrence of B-Cell Receptor Rearrangements

Claudia Haferlach, Wencke Walter, Heiko Mueller, Sandra Huber, Constance Regina Baer, Stephan Hutter, Manja Meggendorfer, Gregor Hoermann, Wolfgang Kern, Torsten Haferlach

Blood (2023) 142 (Supplement 1): 3170.

https://doi.org/10.1182/blood-2023-185867

Published: 2023

Journal Articles

Characterization of Cases with the Rare Cytogenetic Abnormality I(7)(p10) Reveals an Association with IDH2 Mutated Acute Myeloid Leukemia

Anna Stengel, Manja Meggendorfer, Constance Regina Baer, Niroshan Nadarajah, Stephan Hutter, Wolfgang Kern, Torsten Haferlach, Claudia Haferlach

Blood (2023) 142 (Supplement 1): 5987.

https://doi.org/10.1182/blood-2023-179844

Published: 2023

Journal Articles

Classification of Philadelphia-Negative MPN As Low Risk and High Risk MPN Based on Peripheral Blood Values and Molecular Genetics Only

Sandra Huber, Gregor Hoermann, Manja Meggendorfer, Stephan Hutter, Constance Regina Baer, Wolfgang Kern, Torsten Haferlach, Claudia Haferlach

Blood (2023) 142 (Supplement 1): 3184.

https://doi.org/10.1182/blood-2023-174872

Published: 2023

Journal Articles

Parallel Genomic Analysis from Paired Bone Marrow and Peripheral Blood Samples of 200 Cytopenic Patients

Sandra Huber, Natalie Wossidlo, Torsten Haferlach, Manja Meggendorfer, Stephan Hutter, Gregor Hoermann, Isolde Summerer, Henning Ruge, Constance Regina Baer, Wolfgang Kern, Claudia Haferlach

Blood (2023) 142 (Supplement 1): 198.

https://doi.org/10.1182/blood-2023-174843

Published: 2023

Journal Articles

Can Whole Genome and Whole Transcriptome Sequencing Replace Standard Procedures in CLL Diagnostics?

Heiko Mueller, Wencke Walter, Manja Meggendorfer, Stephan Hutter, Niroshan Nadarajah, Wolfgang Kern, Torsten Haferlach, Claudia Haferlach

Blood (2023) 142 (Supplement 1): 1912.

https://doi.org/10.1182/blood-2023-185732

Published: 2023

Journal Articles

Genomic Landscape of Ccus Compared to MDS Indicates a Potential Applicability of the IPSS-M

Sandra Huber, Constance Regina Baer, Stephan Hutter, Gregor Hoermann, Christian Pohlkamp, Wencke Walter, Manja Meggendorfer, Wolfgang Kern, Torsten Haferlach, Claudia Haferlach

Blood (2023) 142 (Supplement 1): 4609.

https://doi.org/10.1182/blood-2023-177582

Published: 2023

Journal Articles

Proposal ofmyeloid Neoplasms with MYC -Positive Double Minutes As a Distinct Entity

Isolde Summerer, Wencke Walter, Manja Meggendorfer, Torsten Haferlach, Frank Dicker, Stephan Hutter, Niroshan Nadarajah, Constance Regina Baer, Anna Stengel, Wolfgang Kern, John M. Bennett, Claudia Haferlach, Christian Pohlkamp

Blood (2023) 142 (Supplement 1): 2930.

https://doi.org/10.1182/blood-2023-189902

Published: 2023

Journal Articles

The Frequency of Clonal Hematopoiesis Prior to AML and MDS Varies Among the Different Molecularly Defined Who Subtypes

Constance Regina Baer, Sandra Huber, Gregor Hoermann, Manja Meggendorfer, Stephan Hutter, Wolfgang Kern, Torsten Haferlach, Claudia Haferlach

Blood (2023) 142 (Supplement 1): 725.

https://doi.org/10.1182/blood-2023-179737

Published: 2023

Journal Articles

Modification of the ELN Classification 2022 Refines Risk Assessment in MDS/AML Patients

Sandra Huber, Constance Regina Baer, Stephan Hutter, Frank Dicker, Irene Fuhrmann, Manja Meggendorfer, Christian Pohlkamp, Wolfgang Kern, Torsten Haferlach, Claudia Haferlach, Gregor Hoermann

Blood (2023) 142 (Supplement 1): 61.

https://doi.org/10.1182/blood-2023-179822

Published: 2023

Journal Articles

A Proposal for a Classification of Ccus, MDS and AML Primarily Based on Genetic Abnormalities Considering the Biological Continuum of These Entities

Claudia Haferlach, Sandra Huber, Constance Regina Baer, Stephan Hutter, Manja Meggendorfer, Wolfgang Kern, Gregor Hoermann, Torsten Haferlach

Blood (2023) 142 (Supplement 1): 6492.

https://doi.org/10.1182/blood-2023-179188

Published: 2023

Journal Articles

Detecting the Unusual without Compromising Diagnostic Accuracy - a Prospective WGS/Wts Pilot Study in Acute Leukemias Provided Additional Information for Diagnosis, Prognosis and Treatment

Manja Meggendorfer, Marietta Truger, Wencke Walter, Constance Baer, Stephan Hutter, Niroshan Nadarajah, Wolfgang Kern, Torsten Haferlach, Claudia Haferlach

Blood (2022) 140 (Supplement 1): 4959–4960.

https://doi.org/10.1182/blood-2022-159428

Published: 2022

Journal Articles

Evaluation of a Transparent Artificial Intelligence (AI) Disease Classification System with Whole Genome Sequencing (WGS) and Whole Transcriptome Sequencing (WTS) Data in a Prospective Study with 325 Cases

Niroshan Nadarajah, Sven Maschek, Stephan Hutter, Manja Meggendorfer, Wolfgang Kern, Claudia Haferlach, Torsten Haferlach

Blood (2022) 140 (Supplement 1): 1915–1916.

https://doi.org/10.1182/blood-2022-169093

Published: 2022

Journal Articles

Proximally Biased V(D)J Recombination and Evolution of Non-Productive Clones in B-Cell Precursor Acute Lymphocytic Leukemia with KMT2A :: AFF1 Fusion Genes

Heiko Mueller, Wencke Walter, Stephan Hutter, Niroshan Nadarajah, Frank Dicker, Manja Meggendorfer, Qingsong Gao, Ilaria Iacobucci, Charles G. Mullighan, Wolfgang Kern, Torsten Haferlach, Claudia Haferlach

Blood (2022) 140 (Supplement 1): 6348–6349.

https://doi.org/10.1182/blood-2022-162382

Published: 2022

Journal Articles

Myeloid Neoplasms with MYC -Positive Double Minutes, a Specific Subgroup?

Isolde Summerer, Wencke Walter, Manja Meggendorfer, Torsten Haferlach, Stephan Hutter, Niroshan Nadarajah, Constance Baer, Anna Stengel, Wolfgang Kern, Claudia Haferlach

Blood (2022) 140 (Supplement 1): 9142–9143.

https://doi.org/10.1182/blood-2022-166102

Published: 2022

Journal Articles

Interplay of TP53 Allelic State, Blast Count and Karyotype on Survival of Patients with AML and MDS

Anna Stengel, Manja Meggendorfer, Wencke Walter, Constance Baer, Niroshan Nadarajah, Stephan Hutter, Wolfgang Kern, Torsten Haferlach, Claudia Haferlach

Blood (2022) 140 (Supplement 1): 2073–2074.

https://doi.org/10.1182/blood-2022-159388

Published: 2022

Journal Articles

RUNX1 Mutated AML and MDS: Similarities, Differences and Molecular Factors Leading to Disease Progression

Anna Stengel, Manja Meggendorfer, Wencke Walter, Constance Baer, Niroshan Nadarajah, Stephan Hutter, Wolfgang Kern, Torsten Haferlach, Claudia Haferlach

Blood (2022) 140 (Supplement 1): 2990–2991.

https://doi.org/10.1182/blood-2022-159379

Published: 2022

Journal Articles

IDH2 mutations in Hematological Malignancies: Distribution, Hot Spots, Clonal Development and Identification of a Novel (cyto-)Genetically Defined Subgroup

Anna Stengel, Manja Meggendorfer, Wencke Walter, Constance Baer, Niroshan Nadarajah, Stephan Hutter, Wolfgang Kern, Torsten Haferlach, Claudia Haferlach

Blood (2022) 140 (Supplement 1): 3405–3406.

https://doi.org/10.1182/blood-2022-158979

Published: 2022

Journal Articles

MDS Classification - Do We Still Have to Count Blasts?

Claudia Haferlach, Sandra Huber, Heiko Mueller, Constance Baer, Gregor Hoermann, Manja Meggendorfer, Stephan Hutter, Wolfgang Kern, Torsten Haferlach

Blood (2022) 140 (Supplement 1): 1130–1131.

https://doi.org/10.1182/blood-2022-162147

Published: 2022

NARROW

Comparing malignant monocytosis across the updated WHO and ICC classifications of 2022

Germ line variant GFI1-36N affects DNA repair and sensitizes AML cells to DNA damage and repair therapy

Whole Genome and Transcriptome Sequencing of 21 Paired Chronic and Blast Phase CML Cases: Acquisition of Genomic Alterations, Changes in the Transcriptomic Profiles and Occurrence of B-Cell Receptor Rearrangements

Characterization of Cases with the Rare Cytogenetic Abnormality I(7)(p10) Reveals an Association with IDH2 Mutated Acute Myeloid Leukemia

Classification of Philadelphia-Negative MPN As Low Risk and High Risk MPN Based on Peripheral Blood Values and Molecular Genetics Only

Parallel Genomic Analysis from Paired Bone Marrow and Peripheral Blood Samples of 200 Cytopenic Patients

Can Whole Genome and Whole Transcriptome Sequencing Replace Standard Procedures in CLL Diagnostics?

Genomic Landscape of Ccus Compared to MDS Indicates a Potential Applicability of the IPSS-M

Proposal ofmyeloid Neoplasms with MYC -Positive Double Minutes As a Distinct Entity

The Frequency of Clonal Hematopoiesis Prior to AML and MDS Varies Among the Different Molecularly Defined Who Subtypes

Modification of the ELN Classification 2022 Refines Risk Assessment in MDS/AML Patients

A Proposal for a Classification of Ccus, MDS and AML Primarily Based on Genetic Abnormalities Considering the Biological Continuum of These Entities

Detecting the Unusual without Compromising Diagnostic Accuracy - a Prospective WGS/Wts Pilot Study in Acute Leukemias Provided Additional Information for Diagnosis, Prognosis and Treatment

Evaluation of a Transparent Artificial Intelligence (AI) Disease Classification System with Whole Genome Sequencing (WGS) and Whole Transcriptome Sequencing (WTS) Data in a Prospective Study with 325 Cases

Proximally Biased V(D)J Recombination and Evolution of Non-Productive Clones in B-Cell Precursor Acute Lymphocytic Leukemia with KMT2A :: AFF1 Fusion Genes

Myeloid Neoplasms with MYC -Positive Double Minutes, a Specific Subgroup?

Interplay of TP53 Allelic State, Blast Count and Karyotype on Survival of Patients with AML and MDS

RUNX1 Mutated AML and MDS: Similarities, Differences and Molecular Factors Leading to Disease Progression

IDH2 mutations in Hematological Malignancies: Distribution, Hot Spots, Clonal Development and Identification of a Novel (cyto-)Genetically Defined Subgroup

MDS Classification - Do We Still Have to Count Blasts?

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American Society of Hematology

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ASH Publications

American Society of Hematology

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