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Andreas Lennartsson
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Journal Articles

Somatic Mutations and DNA Hypermethylation at Enhancers and Promoters Identify Distinct Subtypes within Lower-Risk Myelodysplastic Syndromes

David Rombaut, Tobias Tekath, Sarah Sandmann, Simon Crouch, Aniek O. de Graaf, Olivier Kosmider, Magnus Tobiasson, Andreas Lennartsson, Bert A. Van der Reijden, Sophie Park, Maud D'Aveni, Bohrane Slama, Emmanuelle Clappier, Pierre Fenaux, Lionel Ades, Arjan A. van de Loosdrecht, Saskia MC Langemeijer, Argiris S. Symeonidis, Jaroslav Čermák, Claude Preudhomme, Aleksandar Savic, Ulrich Germing, Reinhard Stauder, David T. Bowen, Corine J. Van Marrewijk, Elsa Bernard, Alexandra Smith, Daniel Painter, Theo J.M. de Witte, Eva Hellstrom Lindberg, Julian Varghese, Martin Dugas, Joost H.A. Martens, Luca Malcovati, Joop H. Jansen, Michaela Fontenay
Journal: Blood
Blood (2023) 142 (Supplement 1): 4587.
https://doi.org/10.1182/blood-2023-180071
Published: 2023
Journal Articles

AML displays increased CTCF occupancy associated with aberrant gene expression and transcription factor binding

Huthayfa Mujahed, Sophia Miliara, Anne Neddermeyer, Sofia Bengtzén, Christer Nilsson, Stefan Deneberg, Lina Cordeddu, Karl Ekwall, Andreas Lennartsson, Sören Lehmann
Journal: Blood
Blood (2020) 136 (3): 339–352.
https://doi.org/10.1182/blood.2019002326
Published: 2020
Includes: Supplemental data
Journal Articles

Single-Cell Analysis of the Transcriptional Response in AML Patients Treated with BET-Inhibitors

Sophia Miliara, BSc, MSc, PhD, Bogumil Kaczkowski, PhD, Takahiro Suzuki, PhD, Huthayfa Mujahed, MSc, Maasaki Furuno, PhD, Satoshi Takizawa, Harukazu Suzuki, PhD, Takahiro Arakawa, Soren Lehmann, MD PhD, Andreas Lennartsson, PhD, Erik Arner, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 5120.
https://doi.org/10.1182/blood-2018-99-117849
Published: 2018
Journal Articles

Cancer-specific changes in DNA methylation reveal aberrant silencing and activation of enhancers in leukemia

e-blood
Ying Qu, Lee Siggens, Lina Cordeddu, Verena I. Gaidzik, Kasper Karlsson, Lars Bullinger, Konstanze Döhner, Karl Ekwall, Sören Lehmann, Andreas Lennartsson
Journal: Blood
Blood (2017) 129 (7): e13–e25.
https://doi.org/10.1182/blood-2016-07-726877
Published: 2017
Includes: Supplemental data
Journal Articles

Mutations in Histone Modulators Are Associated with Prolonged Survival during Azacitidine Therapy

Magnus Tobiasson, MD, Donal McLornan, MDPhD, Mohsen Karimi, Marios Dimitriou, PhD, Monika Jansson, Asmaa Ben Azenkoud, Martin Jädersten, Greger Lindberg, Hani Abdulkadir, Austin G. Kulasekararaj, MBBS, MD MRCP, FRCPath, Johanna Ungerstedt, Associate Professor, Andreas Lennartsson, Karl Ekwall, Ghulam J Mufti, Eva Hellström-Lindberg, MD PhD
Journal: Blood
Blood (2015) 126 (23): 2839.
https://doi.org/10.1182/blood.V126.23.2839.2839
Published: 2015
Journal Articles

Mutations in Histone Modulators and HOXA5 Methylation Levels Affects Survival in Azacitidine Treated MDS Patients

Magnus Tobiasson, MD, Mohsen Karimi, Marios Dimitriou, Ying Qu, MDM.Sc, Andreas Lennartsson, PhD, Hani Abdulkadir Ali, Ashwin Unnikrishnan, PhD, Martin Jadersten, MDPhD, Monika Jansson, Asmaa Ben Azenkoud, John E Pimanda, MD PhD, Karl Ekwall, Prof, Johanna Ungerstedt, MD PhD, Soren Lehmann, MD PhD, Eva Hellstrom-Lindberg, MD PhD
Journal: Blood
Blood (2014) 124 (21): 4613.
https://doi.org/10.1182/blood.V124.21.4613.4613
Published: 2014
Journal Articles

High-throughput transcription profiling identifies putative epigenetic regulators of hematopoiesis

e-blood
Punit Prasad, Michelle Rönnerblad, Erik Arner, Masayoshi Itoh, Hideya Kawaji, Timo Lassmann, Carsten O. Daub, Alistair R. R. Forrest, Andreas Lennartsson, Karl Ekwall
Journal: Blood
Blood (2014) 123 (17): e46–e57.
https://doi.org/10.1182/blood-2013-02-483537
Published: 2014
Includes: Supplemental data
Journal Articles

Analysis of the DNA methylome and transcriptome in granulopoiesis reveals timed changes and dynamic enhancer methylation

e-blood
Michelle Rönnerblad, Robin Andersson, Tor Olofsson, Iyadh Douagi, Mohsen Karimi, Sören Lehmann, Ilka Hoof, Michiel de Hoon, Masayoshi Itoh, Sayaka Nagao-Sato, Hideya Kawaji, Timo Lassmann, Piero Carninci, Yoshihide Hayashizaki, Alistair R. R. Forrest, Albin Sandelin, Karl Ekwall, Erik Arner, Andreas Lennartsson
Journal: Blood
Blood (2014) 123 (17): e79–e89.
https://doi.org/10.1182/blood-2013-02-482893
Published: 2014
Includes: Supplemental data
Journal Articles

Analysis of DNA Methylation and Transcription During Granulopoiesis Reveals Timed Methylation Changes in Low CpG Areas That Correlate with Changed Transcriptional Activity.

Rönnerblad Michelle, Olofsson Tor, Prof, Iyadh Douagi, PhD, Sören Lehmann, MD, PhD, Karl Ekwall, Prof, Erik Arner, PhD, Andreas Lennartsson, PhD
Journal: Blood
Blood (2012) 120 (21): 2334.
https://doi.org/10.1182/blood.V120.21.2334.2334
Published: 2012
Journal Articles

Genome-Wide DNA Methylation Analysis Shows Enrichment of Differential Methylation in “Open Seas” and Enhancers and Reveals Hypomethylation in DNMT3A Mutated Cytogenetically Normal AML (CN-AML)

Ying Qu, MD, M.Sc, Andreas Lennartsson, PhD, Verena I. Gaidzik, MD, Ph.D, Stefan Deneberg, MD, Ph.D, Sofia Bengtzén, Mohsen Karimi Arzenani, PhD, Lars Bullinger, MD, PhD, Konstanze Döhner, MD, Ph.D, Sören Lehmann, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 653.
https://doi.org/10.1182/blood.V120.21.653.653
Published: 2012
Journal Articles

Prognostic DNA methylation patterns in cytogenetically normal acute myeloid leukemia are predefined by stem cell chromatin marks

Stefan Deneberg, Philippe Guardiola, Andreas Lennartsson, Ying Qu, Verena Gaidzik, Odile Blanchet, Mohsen Karimi, Sofia Bengtzén, Hareth Nahi, Bertil Uggla, Ulf Tidefelt, Martin Höglund, Christer Paul, Karl Ekwall, Konstanze Döhner, Sören Lehmann
Journal: Blood
Blood (2011) 118 (20): 5573–5582.
https://doi.org/10.1182/blood-2011-01-332353
Published: 2011
Includes: Supplemental data
Journal Articles

Global and HOX Gene DNA Methylation In Normal Karyotype Acute Myeloid Leukemia: Clinical Implications and Molecular Correlations

Stefan Deneberg, MD, Andreas Lennartsson, PhD, Bertil Uggla, MD, PhD, Verena Gaidzik, Andrea Corbacioglu, PhD, Hareth Nahi, MD, PhD, Konstanze Dohner, MD, PhD, Karl Ekwall, MD, PhD, Ulf Tidefelt, MD, PhD, Martin Hoglund, MD, PhD, Sören Lehmann, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 231.
https://doi.org/10.1182/blood.V116.21.231.231
Published: 2010