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Claude Preudhomme
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Journal Articles

Secondary Genetic Alterations and Measurable Residual Disease in Core Binding Factor Acute Myeloid Leukemia - a Study from the Acute Leukemia French Intergroup

Loic Vasseur, Matthieu Duchmann, Nicolas Duployez, Emmanuel Raffoux, Celine Berthon, Mael Heiblig, Alexis Genthon, Thorsten Braun, Mathieu Leclerc, Delphine Lebon, Sylvain Chantepie, Jean-Baptiste Micol, Juliette Lambert, Christian Recher, Marie-Lorraine Chrétien, Thomas Cluzeau, Julien Vaidie, Jean-Valère Malfuson, Madalina Uzunov, Arnaud Pigneux, Pierre Peterlin, Sihem Tarfi, Pierre Hirsch, Dominique Penther, Eric Jourdan, Karine Celli-Lebras, Claude Preudhomme, Hervé Dombret, Jérôme Lambert, Nicolas Boissel, Raphael Itzykson
Journal: Blood
Blood (2024) 144 (Supplement 1): 227.
https://doi.org/10.1182/blood-2024-194060
Published: 2024
Journal Articles

Flow MRD Monitoring Combining Laip/Dfn and CD34+CD38- LSCs Is a Strong Predictor of Outcome in Adult AML Independently of the ELN-2022 Risk: First Results from the Multicentric Acute Leukemia French Intergroup MRD Flow Network

Adriana Plesa, Stéphanie Mathis, Florent Dumezy, Anne-Catherine Lhoumeau, Veronique Saada, Isabelle Arnoux, Jennifer Osman, Nicolas Chapuis, Franck Geneviève, Mikael Roussel, Delphine Manzoni, Anne Roggy, Remi Letestu, Veronique Harrivel, Elsa Bera, Jean Feuillard, Hélène Lapillonne, Richard Veyrat-Masson, Tatiana Raskovalova, Bouchra Badaoui, Valerie Bardet, Caroline Mayeur-Rousse, Francois Vergez, Jean Philippe Vial, Valerie Goncalves Monteiro, Frédéric Feger, Dominique Penther, Isabelle Luquet, Eric Delabesse, Nicolas Duployez, Karine Celli-Lebras, Mathilde Hunault, Raphael Itzykson, Arnaud Pigneux, Christian Récher, Hervé Dombret, Claude Preudhomme, Christophe Roumier
Journal: Blood
Blood (2024) 144 (Supplement 1): 226.
https://doi.org/10.1182/blood-2024-205457
Published: 2024
Journal Articles

Favourable Outcomes in Newly Diagnosed Paediatric AML with Gemtuzumab Ozogamicin and Risk-Stratified Therapy: Results from the International Phase III Myechild 01 Trial

Brenda Gibson, Andre Baruchel, Andrew Moore, Shanna Maycock, Owen Smith, Geoff Shenton, Jean-Pierre Bourquin, Yves Bertrand, Nicholas Heaney, Anna Lawson, Persis Jal Amrolia, Gerard Michel, Jean-Hugues Dalle, Marc Ansari, Hélène Lapillonne, Richard Dillon, Jelena Jovanovic, Siobhan Cross, Paul Virgo, Lucy Wheeler, Christophe Roumier, Nicolas Duployez, Christine Harrison, Claire Schwab, Wendy Cuccuini, Marina Lafage-Pochitaloff, Claude Preudhomme, Paresh Vyas, Pierre Hirsch, Gareth Veal, David Gillis, Pam Kearns, Guy Leverger, Phil Ancliff, Aimee Jackson, Arnaud Petit
Journal: Blood
Blood (2024) 144 (Supplement 1): 968.
https://doi.org/10.1182/blood-2024-198419
Published: 2024
Journal Articles

Treatments and Outcomes of Adult Patients with AML in the Real-Life - First Report of the French Observational ALFA-PPP Study

Hervé Dombret, Alexandra Coelho, Laurène Fenwarth, Jean-Baptiste Micol, Lionel Ades, Thomas Cluzeau, Emmanuel Raffoux, Sylvain Chantepie, Pierre Arnautou, Mathieu Leclerc, Delphine Lebon, Thorsten Braun, Ollivier Legrand, Claire Bories, Céline Berthon, Juliette Lambert, Ahmad Aljijakli, Emilie Lemasle, Pascal Turlure, Benjamin Carpentier, Jamile Frayfer, Stephanie Haiat, Ambroise Marcais, Isabelle Plantier, Kevin-James Wattebled, Madalina Uzunov, Iona Vaida, Mael Heiblig, Lauris Gastaud, Laure Farnault, Dominique Penther, Nicole Raus, Renaud Buffet, Karine Celli-Lebras, Claude Preudhomme, Nicolas Duployez, Raphael Itzykson, Stephane De Botton
Journal: Blood
Blood (2024) 144 (Supplement 1): 2424.
https://doi.org/10.1182/blood-2024-207226
Published: 2024
Journal Articles

Long Term Follow-up Data after Consolidation Therapy with Ponatinib in Combination with Cytarabine in Patients with FLT3 Mutated Acute Myeloid Leukemia in First Complete Remission

Thibaut Leguay, Laurène Fenwarth, Thomas Cluzeau, Anne Vekoff, Etienne Lengline, Juliette Lambert, Denis Caillot, Mathilde Hunault, Jean-Valère Malfuson, Sylvain Chantepie, Emmanuelle Tavernier, Berengere Gruson, José Fernandes, Pierre Peterlin, Melody Fort, Laure Morisset, Herve Dombret, Claude Preudhomme, Arnaud Pigneux, Philippe Rousselot
Journal: Blood
Blood (2024) 144 (Supplement 1): 2905.
https://doi.org/10.1182/blood-2024-209998
Published: 2024
Journal Articles

Genomic imbalance analysis provides new insight into prognostic factors in adult and pediatric T-ALL

Estelle Balducci, Mathieu Simonin, Nicolas Duployez, Thomas Steimlé, Marie-Emilie Dourthe, Patrick Villarese, Stéphane Ducassou, Isabelle Arnoux, Jean-Michel Cayuela, Marie Balsat, Lucien Courtois, Guillaume Andrieu, Aurore Touzart, Françoise Huguet, Arnaud Petit, Norbert Ifrah, Hervé Dombret, André Baruchel, Elizabeth Macintyre, Claude Preudhomme, Nicolas Boissel, Vahid Asnafi
Journal: Blood
Blood (2024) 144 (9): 988–1000.
https://doi.org/10.1182/blood.2023022154
Published: 2024
Includes: Supplemental data
Journal Articles

Somatic Mutations and DNA Hypermethylation at Enhancers and Promoters Identify Distinct Subtypes within Lower-Risk Myelodysplastic Syndromes

David Rombaut, Tobias Tekath, Sarah Sandmann, Simon Crouch, Aniek O. de Graaf, Olivier Kosmider, Magnus Tobiasson, Andreas Lennartsson, Bert A. Van der Reijden, Sophie Park, Maud D'Aveni, Bohrane Slama, Emmanuelle Clappier, Pierre Fenaux, Lionel Ades, Arjan A. van de Loosdrecht, Saskia MC Langemeijer, Argiris S. Symeonidis, Jaroslav Čermák, Claude Preudhomme, Aleksandar Savic, Ulrich Germing, Reinhard Stauder, David T. Bowen, Corine J. Van Marrewijk, Elsa Bernard, Alexandra Smith, Daniel Painter, Theo J.M. de Witte, Eva Hellstrom Lindberg, Julian Varghese, Martin Dugas, Joost H.A. Martens, Luca Malcovati, Joop H. Jansen, Michaela Fontenay
Journal: Blood
Blood (2023) 142 (Supplement 1): 4587.
https://doi.org/10.1182/blood-2023-180071
Published: 2023
Journal Articles

Venetoclax in Combination with Intermediate Doses of Cytarabine in Consolidation Phase for Acute Myeloid Leukemia Patients in First Complete Remission; Results of the Part 1 of the Phase 1/2 Multicentric Covenidac Study

Lauris Gastaud, Pierre Peterlin, Mathilde Hunault, Emmanuel Raffoux, Sarah Bertoli, Martin Carré, Cecile Pautas, Sylvain Chantepie, Juliette Lambert, Nicolas Duployez, Karine Celli-Lebras, Ariane Mineur, Claude Gardin, Norbert Vey, Arnaud Pigneux, Eric Delabesse, Claude Preudhomme, Adriana Plesa, Francois Vergez, Jean-François Hamel, Herve Dombret, Christian Recher
Journal: Blood
Blood (2023) 142 (Supplement 1): 4261.
https://doi.org/10.1182/blood-2023-173656
Published: 2023
Journal Articles

Involvement of the JAK-STAT Pathway in the Molecular Landscape of Fusion-Free Myeloid Neoplasms with Eosinophilia

Matthieu Groh, Laurène Fenwarth, Augustin Boudry, Elise Fournier, Alice Marceau-Renaut, Julie Abraham, Marly Barry, Philippe Blanche, Quentin Bodard, Thorsten Braun, Safia Chebrek, Rafael Daltro De Oliveira, Matthieu Decamp, Cécile Audrey Durel, Edouard Forcade, Mathieu Gerfaud-Valentin, Camille Golfier, Clement Gourguechon, Nathalie Grardel, Olivier Kosmider, Mathilde Labro, Sarah Melboucy Belkhir, Fatiha Merabet, Adrien Michon, Nihal Martis, Cécile Morice, Stephane Moreau, Antoine Néel, Franck E. Nicolini, Laurent Pascal, Florence Pasquier, Andrea Pieragostini, Catherine Roche-Lestienne, Philippe Rousselot, Anne Thiebaut, Jean-Francois Viallard, Mathieu Wemeau, Claude Preudhomme, Jean-Emmanuel Kahn, Guillaume Lefèvre, Nicolas Duployez
Journal: Blood
Blood (2023) 142 (Supplement 1): 78.
https://doi.org/10.1182/blood-2023-181250
Published: 2023
Journal Articles

Clonal Dynamics of FLT3 -ITD Positive Acute Myeloid Leukemia Patients with Relapsed/Refractory Disease Following Intensive Chemotherapy +/- Midostaurin

Romane Joudinaud, Augustin Boudry, Laurène Fenwarth, Sandrine Geffroy, Mikaël Salson, Herve Dombret, Céline Berthon, Arnaud Pigneux, Delphine Lebon, Lamya Haddaoui, Raphael Itzykson, Christian Recher, Audrey Bidet, Eric Delabesse, Mathilde Hunault, Claude Preudhomme, Nicolas Duployez, Pierre-Yves Dumas
Journal: Blood
Blood (2023) 142 (Supplement 1): 976.
https://doi.org/10.1182/blood-2023-182018
Published: 2023
Journal Articles

The Occurrence of Infection and TP53 Mutation Are Risk Factors for Cardiovascular Toxicity of Acute Myeloid Leukemia Induction Therapy

Hélène Kemp, Laurène Fenwarth, Delphine Lebon, Nicolas Duployez, Etienne Paubelle, Magalie Joris, Amandine Charbonnier, Lydia Montes, Claude Preudhomme, Christophe Tribouilloy, Jean Pierre Marolleau, Pierre Morel
Journal: Blood
Blood (2023) 142 (Supplement 1): 3815.
https://doi.org/10.1182/blood-2023-190177
Published: 2023
Journal Articles

Current Results of Intensive Therapy in Younger Adults with Acute Myeloid Leukemia (AML): The Large Randomized French Backbone Intergroup (BIG)-1 Study on Behalf of the Filo, ALFA, and SFGM-TC Study Groups

Hunault-Berger Mathilde, Cécile Pautas, Sarah Bertoli, Pierre-Yves Dumas, Emmanuel Raffoux, Tony Marchand, Marie Anne Hospital, Mael Heiblig, Sylvain Chantepie, Martin Carré, Pierre Peterlin, Emilie Lemasle, Célestine Simand, Maria Pilar Gallego Hernanz, Anne Huynh, Edouard Forcade, Raynier Devillier, Stéphanie Nguyen Quoc, Nicolas Duployez, Isabelle Luquet, Dominique Penther, Karine Celli-Lebras, Ariane Mineur, Claude Gardin, Gerard Socié, Jean-Yves Cahn, Norbert Ifrah, Norbert Vey, Regis Peffault De Latour, Eric Delabesse, Claude Preudhomme, Jean-François Hamel, Arnaud Pigneux, Christian Recher, Hervé Dombret
Journal: Blood
Blood (2023) 142 (Supplement 1): 967.
https://doi.org/10.1182/blood-2023-179376
Published: 2023
Journal Articles

Tetraspanin CD81 Supports Cancer Stem Cell Function and Represents a Therapeutic Vulnerability in Acute Myeloid Leukemia

Fanny Gonzales, Pauline Peyrouze, Thomas Boyer, Soizic Guihard, Francois Sevrin, Djohana Laurent, Adriana Plesa, Adeline Barthelemy, Antonino Bongiovanni, Claude Preudhomme, Nicolas Duployez, Celine Berthon, Christophe Roumier, Meyling H Cheok
Journal: Blood
Blood (2023) 142 (Supplement 1): 168.
https://doi.org/10.1182/blood-2023-186957
Published: 2023
Journal Articles

Chromothripsis and Genomic Complexity As Pejorative Prognostic Markers in Pediatric and Adult T-ALL

Estelle Balducci, Mathieu Simonin, Nicolas Duployez, Thomas Steimlé, Marie-Emilie Dourthe, Patrick Villarese, Stéphane Ducassou, Isabelle Arnoux, Jean-Michel Cayuela, Marie Balsat, Lucien Courtois, Guillaume P Andrieu, Aurore Touzart, Françoise Huguet, Arnaud Petit, Norbert Ifrah, Hervé Dombret, André Baruchel, Claude Preudhomme, Nicolas Boissel, Vahid Asnafi
Journal: Blood
Blood (2023) 142 (Supplement 1): 2980.
https://doi.org/10.1182/blood-2023-185831
Published: 2023
Journal Articles

Impact of Residence in an Agricultural Zone on AML Characteristics

Vincent Marmouset, Berengere Gruson, Veronique Harrivel, Céline Berthon, Nicolas Duployez, Claude Preudhomme, Jean Pierre Marolleau, Pierre Morel, Carine Hauspie, Stéphane Morisset, Delphine Lebon
Journal: Blood
Blood (2023) 142 (Supplement 1): 2842.
https://doi.org/10.1182/blood-2023-173171
Published: 2023
Journal Articles

Hyperleukocytosis Increases the Risk of Early Relapses Independently of Genetics in AML

Raphaël Liévin, Nicolas Duployez, Loïc Vasseur, Juliette Lambert, Mael Heiblig, Mathilde Hunault, Claude Gardin, Stephane De Botton, Elise Fournier, Cecile Pautas, Christine Terré, Eric Delabesse, Norbert Ifrah, Arnaud Pigneux, Celli-Lebras Karine, Christian Recher, Claude Preudhomme, Herve Dombret, Raphael Itzykson
Journal: Blood
Blood (2023) 142 (Supplement 1): 4322.
https://doi.org/10.1182/blood-2023-173614
Published: 2023
Journal Articles

Phase I/II Clinical Trial Evaluating Azacitidine + Venetoclax + Donor Lymphocyte Infusion in Post-Transplant Relapse Myelodysplastic Syndromes and Acute Myeloid Leukemia: Preliminary Results of Ventograft, a GFM Study

Thomas Cluzeau, Marie Sebert, Michael Loschi, Lionel Ades, Sylvain Thepot, Martin Carre, Nicolas Duployez, Rosa Sapena, Fatiha Chermat, Claude Preudhomme, Pierre Fenaux, Marie Robin
Journal: Blood
Blood (2023) 142 (Supplement 1): 3246.
https://doi.org/10.1182/blood-2023-178021
Published: 2023
Journal Articles

Long-Term Evolution of Somatic Mutations in Patients with Del(5q) MDS Early Treated with Lenalidomide in the Sintra-Rev Clinical Trial: Safe and Effecitive Approach?

Sofía M Toribio Castelló, Felix Lopez-Cadenas, Claude Preudhomme, Angela Villaverde Ramiro, Laurène Fenwarth, Eva Lumbreras, Teresa González, Mónica Del Rey, Blanca Xicoy, Aline Renneville, Joaquín Sánchez-Garcia, Rosa Coll, Bohrane Slama, José Ángel Hernández-Rivas, Sylvain Thepot, Teresa Bernal, Agnès Guerci-Bresler, Katharina Götze, Jesús María Hernández-Rivas, Pierre Fenaux, Consuelo Del Cañizo, Maria Diez-Campelo
Journal: Blood
Blood (2022) 140 (Supplement 1): 9740–9743.
https://doi.org/10.1182/blood-2022-168599
Published: 2022
Journal Articles

Evaluation of Lenalidomide (LEN) Vs Placebo in Non-Transfusion Dependent Low Risk Del(5q) MDS Patients. Final Results of Sintra-REV Phase III International Multicenter Clinical Trial

Félix López Cadenas, Eva Lumbreras, Teresa González, Blanca Xicoy, Joaquín Sánchez-García, Rosa Coll, Bohrane Slama, José Ángel Hernández-Rivas, Sylvain Thepot, Teresa Bernal, Agnès Guerci-Bresler, Guillermo Sanz, Joan Bargay, Maria Luz Amigo, Raquel De Paz Arias, Claude Preudhomme, Aristoteles Giagounidis, Uwe Platzbecker, Stefan Wickenhauser, Katharina S. Goetze, Ali Arar, Jesús M Hernández Rivas, Sofía M Toribio Castelló, Pierre Fenaux, Consuelo Del Cañizo, Maria Diez-Campelo
Journal: Blood
Blood (2022) 140 (Supplement 1): 1109–1111.
https://doi.org/10.1182/blood-2022-168718
Published: 2022
Journal Articles

Persistence of Mutations in Complete Remission Including DNMT3A , TET2 and ASXL1 Mutations Is Associated with Worse Prognosis in Patients with Acute Myeloid Leukemia Treated in ALFA 0702 Study

Pierre Hirsch, Jérôme Lambert, Maxime Bucci, Caroline Deswarte, Juliette Lambert, Laurène Fenwarth, Herve Dombret, Nicolas Duployez, Claude Preudhomme, Raphael Itzykson, Francois Delhommeau
Journal: Blood
Blood (2022) 140 (Supplement 1): 549–550.
https://doi.org/10.1182/blood-2022-166713
Published: 2022