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Journal Articles

Laboratories Can Reliably Detect Clinically Relevant Variants in the TP53 Gene below 10 % Allelic Frequency: A Multicenter Study of ERIC, the European Research Initiative on CLL

Sarka Pavlova, Jitka Malcikova, Lenka Radova, Silvia Bonfiglio, Jack B. Cowland, Christian Brieghel, Mette Klarskov Andersen, Maria Karypidou, Bella V Biderman, Michael Doubek, Gregory Lazarian, Inmaculada Rapado, Matthijs Vynck, Naomi Porret, Martin Andres, Dina Rosenberg, Dvora Sahar, Carolina Martinez-Laperche, Ismael Buño Borde, Andrew Hindley, Julio Bravo Sánchez, José García-Marco, Alicia Serrano, Blanca Ferrer Lores, Concepción Fernández-Rodriguez, Beatriz Bellosillo, Stephan Stilgenbauer, Eugen Tausch, Hero Nikdin, Fiona Quinn, Emer Atkinson, Lisette Van De Corput, Cafer Yildiz, Cristina Bilbao, Yanira Florido, Christian Thiede, Caroline Schuster, Anastazja Stoj, Sylwia Czekalska, Anastasia Chatzidimitriou, Stamatia Laidou, Audrey Bidet, Charles Dussiau, Friedel Nollet, Giovanna Piras, Tereza Borosova, Terezia Kurucova, Maria Monne, Svetlana Smirnova, Evgeny Nikitin, Ivan Sloma, Marie-Helene Delfau, Laetitia Largeaud, Loic Ysebaert, Peter J. M. Valk, Amy Christian, Renata Walewska, Marta Sebastião, Maria Gomes da Silva, Piero Galieni, Mario Angelini, Davide Rossi, Valeria Spina, Sónia Matos, Vânia Martins, David Donaldson, Tomasz Stoklosa, Monika Pepek, Panagiotis Baliakas, Rafa Andreu, Irene Luna, Tiina Kahre, Ülle Murumets, Sophie Laird, Daniel Ward, Miguel Alcoceba, Ana Balanzategui, Lydia Scarfo, Francesca Gandini, Ettore Zapparoli, Adoracion Blanco, Pau Abrisqueta Costa, Ana E. Rodriguez, Maria Rocio Benito Sanchez, Frédéric Davi, Clothilde Bravetti, Paula Gameiro, Joaquin Martinez-Lopez, Barbara Tazon, Fanny Baran-Marszak, Zadie Davies, Mark Caterwood, Andrey B Sudarikov, Richard Rosenquist, Carsten Utoft Niemann, Kostas Stamatopoulos, Paolo Ghia, Sarka Pospisilova

Blood (2023) 142 (Supplement 1): 200.

https://doi.org/10.1182/blood-2023-173235

Published: 2023

Journal Articles

Mutation of Epigenetic Regulators at Diagnosis Is an Independent Predictor of Tyrosine Kinase Inhibitor Treatment Failure: A Report from the Residiag Study

Hippolyte Guerineau, Jean-Michel Cayuela, Stéphanie Dulucq, Violaine Tran Quang, Sihem Tarfi, Quentin Barathon, Corine Joy, Orianne Wagner-Ballon, Stéphane Morisset, Franck E. Nicolini, Lydia Roy, Sébastien Maury, Gabriel Etienne, Delphine Rea, Ivan Sloma

Blood (2023) 142 (Supplement 1): 4540.

https://doi.org/10.1182/blood-2023-186271

Published: 2023

Journal Articles

Erythroid Chimerism Measurement As a Predictive Tool of Bone Marrow Transplantation Outcome in Sickle Cell Disease

Nicolas Hebert, Meghan Perkins, Ivan Sloma, Laura Bencheikh, Florence Beckerich, Rabah Redjoul, Stephane Moutereau, France Pirenne, Sébastien Maury, Gonzalo De Luna, Pablo Bartolucci

Blood (2021) 138 (Supplement 1): 2028.

https://doi.org/10.1182/blood-2021-144844

Published: 2021

Journal Articles

NUP98-HOXA9 -Initiates Molecular and Biologic Features of Disease Progression in a Humanized Model of CML

Ivan Sloma, PharmD, PhD, Philip Beer, PhD FRCPath, MRCP, Christophe Desterke, PhD, Elizabeth Bulaeva, Misha Bilenky, Michelle Moksa, Kamini Raghuram, Cedric Brimacombe, Karen Lambie, Ali G Turhan, MD PhD, Orianne Wagner-Ballon, MD PhD, Philippe Gaulard, MD PhD, R. Keith Humphries, MD PhD, Martin Hirst, PhD BS, Connie J. Eaves, PhD

Blood (2019) 134 (Supplement_1): 4139.

https://doi.org/10.1182/blood-2019-127839

Published: 2019

Journal Articles

The Absolute Count of Circulating, Classical, CD14 ++ /CD16 - Monocytes Is a Poor Prognosis Marker in Chronic Myelomonocytic Leukemia (CMML)

Matthieu Jestin, Sihem Tarfi, PharmD, Bouchra Badaoui, PharmD, Nicolas Freynet, PharmD, Ivan Sloma, PharmD,PhD, Margot Morabito, Sébastien Maury, MD PhD, Pierre Fenaux, MD PhD, Eric Solary, MD PhD, Dorothée Selimoglu-Buet, PhD, Orianne Wagner Ballon, MD PhD

Blood (2019) 134 (Supplement_1): 4242.

https://doi.org/10.1182/blood-2019-121794

Published: 2019

Journal Articles

Aryl Hydrocarbon Receptor (AhR) Pathway Directly Controls Hematopoietic Proliferation in Chronic Myeloid Leukemia (CML) and Its Inhibition Allows Massive Expansion of Leukemic Progenitors and Stem Cells

Melanie Gentil, MD, Patricia Hugues, Gladys Telliam, Ivan Sloma, PharmD,PhD, Seda Baykal, Jerome Artus, PhD, Agnes Guerci, MD, Hyacinthe Johnson Ansa, Adlen Foudi, PhD, Annelise Bennaceur-Griscelli, MD PhD, Ali G Turhan, MD PhD

Blood (2015) 126 (23): 4013.

https://doi.org/10.1182/blood.V126.23.4013.4013

Published: 2015

Journal Articles

A Bio-Integrative Approach Identifies an Inflammatory Signature in Chronic Myeloid Leukemia (CML) Stem Cells That Is Highly Perturbed in CML Blast Crisis and Involves REL transcription Factor

Christophe Desterke, PhD, Ludovic Marie-Sainte, Amine Sbitti, PhD, Ali Naama, Annelise Bennaceur-Griscelli, MD PhD, Ali G Turhan, MD PhD, Ivan Sloma, PharmD,PhD

Blood (2015) 126 (23): 4017.

https://doi.org/10.1182/blood.V126.23.4017.4017

Published: 2015

Journal Articles

Disruption of IKAROS activity in primitive chronic-phase CML cells mimics myeloid disease progression

Philip A. Beer, David J. H. F. Knapp, Paul H. Miller, Nagarajan Kannan, Ivan Sloma, Kathy Heel, Sonja Babovic, Elizabeth Bulaeva, Gabrielle Rabu, Jefferson Terry, Brian J. Druker, Marc M. Loriaux, Keith R. Loeb, Jerald P. Radich, Wendy N. Erber, Connie J. Eaves

Blood (2015) 125 (3): 504–515.

https://doi.org/10.1182/blood-2014-06-581173

Published: 2015

Includes: Supplemental data

Journal Articles

Whole Genome Sequencing Of Chronic Myeloid Leukemia (CML)-Derived Induced Pluripotent Stem Cells (iPSC) Reveals Faithful Genocopying Of Highly Mutated Primary Leukemic Cells

Ivan Sloma, PharmD, PhD, Maria Teresa Mitjavila-Garcia, PhD, Olivier Feraud, Noufissa Oudrhiri, Lucie Tosca, PharmD, PhD, Sanaa El Marsafy, MD, PhD, Emilie Gobbo, Dominique Divers, Alexis Proust, Frank Griscelli, PharmD PhD, Gerard Tachdjian, MD, PhD, Marco A. Marra, PhD, Connie J Eaves, PhD, Annelise Bennaceur-Griscelli, MD, PhD, Ali G Turhan, MD, PhD

Blood (2013) 122 (21): 514.

https://doi.org/10.1182/blood.V122.21.514.514

Published: 2013

Journal Articles

A Novel TWIST2-ID2 Axis That Modulates The Growth and Imatinib Sensitivity Of CML CD34+ Cells

Yun Zhao, PhD, Wenjuan Ma, Xiuyan Zhang, Jiangxia Cui, Ivan Sloma, PhD, Haixia Zhou, Depei Wu, MD, Connie J Eaves, PhD

Blood (2013) 122 (21): 511.

https://doi.org/10.1182/blood.V122.21.511.511

Published: 2013

Journal Articles

Disruption Of Ikaros In Patients’ Chronic Phase CML Cells Induces The Features Of Accelerated Phase Disease

Philip A Beer, MRCP, FRCPath, PhD, Ivan Sloma, PhD, Paul H Miller, BAppSc, David JHF Knapp, BSc, Gabrielle Rabu, BSc, Connie J Eaves, PhD

Blood (2013) 122 (21): 513.

https://doi.org/10.1182/blood.V122.21.513.513

Published: 2013

Journal Articles

Evaluation of Leukemic Stem Cell Persistence in Chronic Myeloid Leukemia (CML) Patients in Complete Molecular Remission Induced by First Line TKI Therapies

Jean-Claude Chomel, PharmD, PhD, Marie Laure Bonnet, Nathalie Sorel, PhD, Ivan Sloma, PharmD, PhD, Alexis Proust, Annelise Bennaceur-Griscelli, MD, PhD, Delphine Rea, MD, PhD, Madalina Uzunov, M.D., Laurence Legros, MD, PhD, Shanti Ame, MD, Anne Marfaing-Koka, Agnès Guerci, MD, Philippe Rousselot, MD, PhD, Ali G Turhan, M.D., PhD

Blood (2012) 120 (21): 3726.

https://doi.org/10.1182/blood.V120.21.3726.3726

Published: 2012

Journal Articles

A Single Chronic Myeloid Leukemia (CML) Stem Cell Harboring Both BCR-ABL and JAK2-V617F Mutation Modeled by Induced Pluripotency

Ivan Sloma, PharmD, PhD, Maria Teresa Mitjavila-Garcia, PhD, Olivier Feraud, Lucie Tosca, PharmD, PhD, Sanaa El Marsafy, MD, PhD, Emilie Gobbo, Dominique Divers, Alexis Proust, Marie Laure Bonnet, Frank Griscelli, PharmD PhD, Gerard Tachdjian, MD, PhD, Annelise Bennaceur-Griscelli, MD, PhD, Ali G Turhan, M.D., PhD

Blood (2012) 120 (21): 3728.

https://doi.org/10.1182/blood.V120.21.3728.3728

Published: 2012

Journal Articles

Longterm Serial Transplantability of BCR-ABL+ Chronic Phase CML Cells Is Predicted by a 6-Week LTC-IC Assay.

Ivan Sloma, PharmD, PhD, Philip A Beer, BM, MRCP, MRCPath, Kyi Min Saw, Matthiew Chan, Karen Lambie, Bobby Johnston, Xiaoyan Jiang, MD, PhD, Connie J. Eaves, PhD

Blood (2012) 120 (21): 2770.

https://doi.org/10.1182/blood.V120.21.2770.2770

Published: 2012

Journal Articles

Combined Targeting of BCR-ABL and JAK2 with ABL and JAK2 Inhibitors Is Effective Against CML Patients' Leukemic Stem/Progenitor Cells.

Donna DeGeer, MSc, Paolo Gallipoli, MD, Min Chen, PhD, Ivan Sloma, PhD, Heather Jorgensen, PhD, Donna Forrest, MD, Karen Lambie, Helen Nakamoto, Kyi Min Saw, Matthew Chan, Kathleen Newmarch, Leon Zhou, Ali G. Turhan, MD, PhD, Ralph B. Arlinghaus, PhD, Allen C. Eaves, MD, FRCPC, PhD, Connie J. Eaves, PhD, Tessa L. Holyoake, PhD, FRCP, FRCPath, Xiaoyan Jiang, MD, PhD

Blood (2010) 116 (21): 3404.

https://doi.org/10.1182/blood.V116.21.3404.3404

Published: 2010

Journal Articles

A Novel Strategy for Expanding Primitive Leukemic Cells from Chronic Phase CML Patients by Forced Overexpression of a NUP98-HOXA10 Homeodomain Fusion Gene.

Ivan Sloma, PhD, Suzan Imren, MD, Yun Zhao, PhD, Keith Humphries, MD, PhD, Connie J. Eaves, PhD

Blood (2008) 112 (11): 1078.

https://doi.org/10.1182/blood.V112.11.1078.1078

Published: 2008

NARROW

Laboratories Can Reliably Detect Clinically Relevant Variants in the TP53 Gene below 10 % Allelic Frequency: A Multicenter Study of ERIC, the European Research Initiative on CLL

Mutation of Epigenetic Regulators at Diagnosis Is an Independent Predictor of Tyrosine Kinase Inhibitor Treatment Failure: A Report from the Residiag Study

Erythroid Chimerism Measurement As a Predictive Tool of Bone Marrow Transplantation Outcome in Sickle Cell Disease

NUP98-HOXA9 -Initiates Molecular and Biologic Features of Disease Progression in a Humanized Model of CML

The Absolute Count of Circulating, Classical, CD14 ++ /CD16 - Monocytes Is a Poor Prognosis Marker in Chronic Myelomonocytic Leukemia (CMML)

Aryl Hydrocarbon Receptor (AhR) Pathway Directly Controls Hematopoietic Proliferation in Chronic Myeloid Leukemia (CML) and Its Inhibition Allows Massive Expansion of Leukemic Progenitors and Stem Cells

A Bio-Integrative Approach Identifies an Inflammatory Signature in Chronic Myeloid Leukemia (CML) Stem Cells That Is Highly Perturbed in CML Blast Crisis and Involves REL transcription Factor

Disruption of IKAROS activity in primitive chronic-phase CML cells mimics myeloid disease progression

Whole Genome Sequencing Of Chronic Myeloid Leukemia (CML)-Derived Induced Pluripotent Stem Cells (iPSC) Reveals Faithful Genocopying Of Highly Mutated Primary Leukemic Cells

A Novel TWIST2-ID2 Axis That Modulates The Growth and Imatinib Sensitivity Of CML CD34+ Cells

Disruption Of Ikaros In Patients’ Chronic Phase CML Cells Induces The Features Of Accelerated Phase Disease

Evaluation of Leukemic Stem Cell Persistence in Chronic Myeloid Leukemia (CML) Patients in Complete Molecular Remission Induced by First Line TKI Therapies

A Single Chronic Myeloid Leukemia (CML) Stem Cell Harboring Both BCR-ABL and JAK2-V617F Mutation Modeled by Induced Pluripotency

Longterm Serial Transplantability of BCR-ABL+ Chronic Phase CML Cells Is Predicted by a 6-Week LTC-IC Assay.

Combined Targeting of BCR-ABL and JAK2 with ABL and JAK2 Inhibitors Is Effective Against CML Patients' Leukemic Stem/Progenitor Cells.

A Novel Strategy for Expanding Primitive Leukemic Cells from Chronic Phase CML Patients by Forced Overexpression of a NUP98-HOXA10 Homeodomain Fusion Gene.

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American Society of Hematology

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American Society of Hematology

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