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Journal Articles

MYC-induced human acute myeloid leukemia requires a continuing IL-3/GM-CSF costimulus

Elizabeth Bulaeva, Davide Pellacani, Naoto Nakamichi, Colin A. Hammond, Philip A. Beer, Alireza Lorzadeh, Michelle Moksa, Annaïck Carles, Misha Bilenky, Sylvain Lefort, Jeremy Shu, Brian T. Wilhelm, Andrew P. Weng, Martin Hirst, Connie J. Eaves

Blood (2020) 136 (24): 2764–2773.

https://doi.org/10.1182/blood.2020006374

Published: 2020

Includes: Supplemental data

Journal Articles

Targeted sequencing in DLBCL, molecular subtypes, and outcomes: a Haematological Malignancy Research Network report

Stuart E. Lacy, Sharon L. Barrans, Philip A. Beer, Daniel Painter, Alexandra G. Smith, Eve Roman, Susanna L. Cooke, Camilo Ruiz, Paul Glover, Suzan J. L. Van Hoppe, Nichola Webster, Peter J. Campbell, Reuben M. Tooze, Russell Patmore, Cathy Burton, Simon Crouch, Daniel J. Hodson

Blood (2020) 135 (20): 1759–1771.

https://doi.org/10.1182/blood.2019003535

Published: 2020

Includes: Supplemental data

Journal Articles

A topological view of human CD34 + cell state trajectories from integrated single-cell output and proteomic data

David J. H. F. Knapp, Colin A. Hammond, Fangwu Wang, Nima Aghaeepour, Paul H. Miller, Philip A. Beer, Davide Pellacani, Michael VanInsberghe, Carl Hansen, Sean C. Bendall, Garry P. Nolan, Connie J. Eaves

Blood (2019) 133 (9): 927–939.

https://doi.org/10.1182/blood-2018-10-878025

Published: 2019

Includes: Supplemental data

Journal Articles

Distinct signaling programs control human hematopoietic stem cell survival and proliferation

David J. H. F. Knapp, Colin A. Hammond, Nima Aghaeepour, Paul H. Miller, Davide Pellacani, Philip A. Beer, Karen Sachs, Wenlian Qiao, WeiJia Wang, R. Keith Humphries, Guy Sauvageau, Peter W. Zandstra, Sean C. Bendall, Garry P. Nolan, Carl Hansen, Connie J. Eaves

Blood (2017) 129 (3): 307–318.

https://doi.org/10.1182/blood-2016-09-740654

Published: 2017

Includes: Supplemental data

Journal Articles

Enhanced and Accelerated Repopulation of Mutant C-Kit Immunodeficient Mice By Transplants of Primary Chronic and Acute Myeloid Leukemic Human Cells

Naoto Nakamichi, MD PhD, Colin A. Hammond, Paul H. Miller, PhD, Katharina Rothe, PhD, Philip A Beer, BM, MRCP, MRCPath, Xiaoyan Jiang, MD PhD, Michael W. Deininger, MD PhD, Connie J. Eaves, PhD

Blood (2016) 128 (22): 4537.

https://doi.org/10.1182/blood.V128.22.4537.4537

Published: 2016

Journal Articles

Disruption of IKAROS activity in primitive chronic-phase CML cells mimics myeloid disease progression

Philip A. Beer, David J. H. F. Knapp, Paul H. Miller, Nagarajan Kannan, Ivan Sloma, Kathy Heel, Sonja Babovic, Elizabeth Bulaeva, Gabrielle Rabu, Jefferson Terry, Brian J. Druker, Marc M. Loriaux, Keith R. Loeb, Jerald P. Radich, Wendy N. Erber, Connie J. Eaves

Blood (2015) 125 (3): 504–515.

https://doi.org/10.1182/blood-2014-06-581173

Published: 2015

Includes: Supplemental data

Journal Articles

Longterm Multilineage Human Hematopoietic Repopulation of Untreated KIT-Mutant Immunodeficient Mice

Paul H. Miller, Gabrielle Rabu, David J.H.F. Knapp, Alice M.S. Cheung, PhD, Kiran Dhillon, Philip A. Beer, MRCP, FRCPath, PhD, Connie J. Eaves, PhD

Blood (2014) 124 (21): 2415.

https://doi.org/10.1182/blood.V124.21.2415.2415

Published: 2014

Journal Articles

Modeling de novo leukemogenesis from human cord blood with MN1 and NUP98HOXD13

Suzan Imren, Michael Heuser, Maura Gasparetto, Philip A. Beer, Gudmundur L. Norddahl, Ping Xiang, Ling Chen, Tobias Berg, Garrett W. Rhyasen, Patricia Rosten, Gyeongsin Park, Yeonsook Moon, Andrew P. Weng, Connie J. Eaves, R. Keith Humphries

Blood (2014) 124 (24): 3608–3612.

https://doi.org/10.1182/blood-2014-04-564666

Published: 2014

Includes: Supplemental data

Journal Articles

Disruption Of Ikaros In Patients’ Chronic Phase CML Cells Induces The Features Of Accelerated Phase Disease

Philip A Beer, MRCP, FRCPath, PhD, Ivan Sloma, PhD, Paul H Miller, BAppSc, David JHF Knapp, BSc, Gabrielle Rabu, BSc, Connie J Eaves, PhD

Blood (2013) 122 (21): 513.

https://doi.org/10.1182/blood.V122.21.513.513

Published: 2013

Journal Articles

Enhanced normal short-term human myelopoiesis in mice engineered to express human-specific myeloid growth factors

Paul H. Miller, Alice M. S. Cheung, Philip A. Beer, David J. H. F. Knapp, Kiran Dhillon, Gabrielle Rabu, Shabnam Rostamirad, R. Keith Humphries, Connie J. Eaves

Blood (2013) 121 (5): e1–e4.

https://doi.org/10.1182/blood-2012-09-456566

Published: 2013

Includes: Supplemental data

Journal Articles

Time Course Studies of the Progeny of Barcoded CD34 + Human Cord Blood Cells Generated in Transplanted NOD/SCID-IL2Rγ −/− Mice Unveil the Clonal Dynamics of Short Term, Intermediate Term and Long Term Repopulating Cells

Alice M.S. Cheung, PhD, Long V. Nguyen, Annaick Carles, Paul H. Miller, Philip A Beer, BM, MRCP, MRCPath, Pawan Pandoh, David Knapp, Kiran Dhillon, Kane Tse, Thomas Zeng, Yongjun Zhao, Martin Hirst, Ph.D., Connie J. Eaves, PhD

Blood (2012) 120 (21): 28.

https://doi.org/10.1182/blood.V120.21.28.28

Published: 2012

Journal Articles

Longterm Serial Transplantability of BCR-ABL+ Chronic Phase CML Cells Is Predicted by a 6-Week LTC-IC Assay.

Ivan Sloma, PharmD, PhD, Philip A Beer, BM, MRCP, MRCPath, Kyi Min Saw, Matthiew Chan, Karen Lambie, Bobby Johnston, Xiaoyan Jiang, MD, PhD, Connie J. Eaves, PhD

Blood (2012) 120 (21): 2770.

https://doi.org/10.1182/blood.V120.21.2770.2770

Published: 2012

Journal Articles

Correlation of blood counts with vascular complications in essential thrombocythemia: analysis of the prospective PT1 cohort

Peter J. Campbell, Cathy MacLean, Philip A. Beer, Georgina Buck, Keith Wheatley, Jean-Jacques Kiladjian, Cecily Forsyth, Claire N. Harrison, Anthony R. Green

Blood (2012) 120 (7): 1409–1411.

https://doi.org/10.1182/blood-2012-04-424911

Published: 2012

Journal Articles

Distinct Human Cell Populations Produce Rapidly Detectable Levels of Neutrophils and Platelets in NOD/SCID-IL-2Receptor Gamma Chain Null Mice Transgenically Engineered to Produce Human Myeloid Growth Factors

Paul H. Miller, Alice M.S. Cheung, PhD, Suzan Imren, MD, Philip A Beer, BM, MRCP, MRCPath, Shabnam Rostamirad, Kiran Dhillon, R. Keith Humphries, MD, PhD, Connie J. Eaves, PhD

Blood (2011) 118 (21): 1892.

https://doi.org/10.1182/blood.V118.21.1892.1892

Published: 2011

Journal Articles

Response: essential thrombocythemia: seeing the wood for the trees

Philip A. Beer, Wendy N. Erber, Peter J. Campbell, Anthony R. Green

Blood (2011) 118 (4): 1180–1181.

https://doi.org/10.1182/blood-2011-05-350215

Published: 2011

Journal Articles

How I treat essential thrombocythemia

Philip A. Beer, Wendy N. Erber, Peter J. Campbell, Anthony R. Green

Blood (2011) 117 (5): 1472–1482.

https://doi.org/10.1182/blood-2010-08-270033

Published: 2011

Journal Articles

JAK2 V617F impairs hematopoietic stem cell function in a conditional knock-in mouse model of JAK2 V617F–positive essential thrombocythemia

Juan Li, Dominik Spensberger, Jong Sook Ahn, Shubha Anand, Philip A. Beer, Cedric Ghevaert, Edwin Chen, Ariel Forrai, Linda M. Scott, Rita Ferreira, Peter J. Campbell, Steve P. Watson, Pentao Liu, Wendy N. Erber, Brian J. P. Huntly, Katrin Ottersbach, Anthony R. Green

Blood (2010) 116 (9): 1528–1538.

https://doi.org/10.1182/blood-2009-12-259747

Published: 2010

Includes: Supplemental data

Journal Articles

Independently acquired biallelic JAK2 mutations are present in a minority of patients with essential thrombocythemia

Philip A. Beer, Christina A. Ortmann, Peter J. Campbell, Anthony R. Green

Blood (2010) 116 (6): 1013–1014.

https://doi.org/10.1182/blood-2010-05-284356

Published: 2010

Journal Articles

The JAK2 46/1 haplotype predisposes to MPL -mutated myeloproliferative neoplasms

Amy V. Jones, Peter J. Campbell, Philip A. Beer, Susanne Schnittger, Alessandro M. Vannucchi, Katerina Zoi, Melanie J. Percy, Mary Frances McMullin, Linda M. Scott, William Tapper, Richard T. Silver, David Oscier, Claire N. Harrison, Harald Grallert, Aliaksei Kisialiou, Paul Strike, Andrew J. Chase, Anthony R. Green, Nicholas C. P. Cross

Blood (2010) 115 (22): 4517–4523.

https://doi.org/10.1182/blood-2009-08-236448

Published: 2010

Includes: Supplemental data

Journal Articles

Two routes to leukemic transformation after a JAK2 mutation–positive myeloproliferative neoplasm

Philip A. Beer, François Delhommeau, Jean-Pierre LeCouédic, Mark A. Dawson, Edwin Chen, David Bareford, Rajko Kušec, Mary Frances McMullin, Claire N. Harrison, Alessandro M. Vannucchi, William Vainchenker, Anthony R. Green

Blood (2010) 115 (14): 2891–2900.

https://doi.org/10.1182/blood-2009-08-236596

Published: 2010

NARROW

MYC-induced human acute myeloid leukemia requires a continuing IL-3/GM-CSF costimulus

Targeted sequencing in DLBCL, molecular subtypes, and outcomes: a Haematological Malignancy Research Network report

A topological view of human CD34 + cell state trajectories from integrated single-cell output and proteomic data

Distinct signaling programs control human hematopoietic stem cell survival and proliferation

Enhanced and Accelerated Repopulation of Mutant C-Kit Immunodeficient Mice By Transplants of Primary Chronic and Acute Myeloid Leukemic Human Cells

Disruption of IKAROS activity in primitive chronic-phase CML cells mimics myeloid disease progression

Longterm Multilineage Human Hematopoietic Repopulation of Untreated KIT-Mutant Immunodeficient Mice

Modeling de novo leukemogenesis from human cord blood with MN1 and NUP98HOXD13

Disruption Of Ikaros In Patients’ Chronic Phase CML Cells Induces The Features Of Accelerated Phase Disease

Enhanced normal short-term human myelopoiesis in mice engineered to express human-specific myeloid growth factors

Time Course Studies of the Progeny of Barcoded CD34 + Human Cord Blood Cells Generated in Transplanted NOD/SCID-IL2Rγ −/− Mice Unveil the Clonal Dynamics of Short Term, Intermediate Term and Long Term Repopulating Cells

Longterm Serial Transplantability of BCR-ABL+ Chronic Phase CML Cells Is Predicted by a 6-Week LTC-IC Assay.

Correlation of blood counts with vascular complications in essential thrombocythemia: analysis of the prospective PT1 cohort

Distinct Human Cell Populations Produce Rapidly Detectable Levels of Neutrophils and Platelets in NOD/SCID-IL-2Receptor Gamma Chain Null Mice Transgenically Engineered to Produce Human Myeloid Growth Factors

Response: essential thrombocythemia: seeing the wood for the trees

How I treat essential thrombocythemia

JAK2 V617F impairs hematopoietic stem cell function in a conditional knock-in mouse model of JAK2 V617F–positive essential thrombocythemia

Independently acquired biallelic JAK2 mutations are present in a minority of patients with essential thrombocythemia

The JAK2 46/1 haplotype predisposes to MPL -mutated myeloproliferative neoplasms

Two routes to leukemic transformation after a JAK2 mutation–positive myeloproliferative neoplasm

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American Society of Hematology

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American Society of Hematology

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