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Journal Articles

KBTBD4-mediated reduction of MYC is critical for hematopoietic stem cell expansion upon UM171 treatment

Jalila Chagraoui, Simon Girard, Laure Mallinger, Nadine Mayotte, Maria Florencia Tellechea, Guy Sauvageau

Blood (2024) 143 (10): 882–894.

https://doi.org/10.1182/blood.2023021342

Published: 2024

Includes: Supplemental data

Journal Articles

Identification of Acute Myeloid Leukemia Cell Surface Therapeutic Targets Using Single Cell RNA Sequencing Supported By Surface Proteomics

Blood (2023) 142 (Supplement 1): 163.

https://doi.org/10.1182/blood-2023-186367

Published: 2023

Journal Articles

UM171 Enhances Fitness and Engraftment of Gene Modified Hematopoietic Stem Cells from Sickle Cells Disease Patients

Boya Liu, Denise Klatt, Yu Zhou, John Manis, Guy Sauvageau, Christian Brendel, David A. Williams

Blood (2023) 142 (Supplement 1): 18.

https://doi.org/10.1182/blood-2023-182099

Published: 2023

Journal Articles

Infusion of UM171-Expanded Cord Blood Led to Excellent Survival in Patients with High-Risk Leukemias: Results from Two Independent Phase II Studies

Filippo Milano, Guy Sauvageau, Gabrielle Thauvette, Nadia M. Bambace, Lea Bernard, Imran Ahmad, Jean Roy, Laura C Roberts, Laurel Thur, Jenna B Pedersen, Ann Dahlberg, Sandra Cohen

Blood (2023) 142 (Supplement 1): 1040.

https://doi.org/10.1182/blood-2023-187446

Published: 2023

Journal Articles

The XPO1-FOXC1-HOX Functional Axis Opens New Therapeutic Avenues to Treat DEK-NUP214 AML Patients

Blood (2023) 142 (Supplement 1): 4302.

https://doi.org/10.1182/blood-2023-174891

Published: 2023

Journal Articles

Deciphering the Boundaries of KBTBD4-CoREST1 Axis Modulation to Maximally Expand Human HSCs

Maria Florencia Florencia Tellechea, Jalila Chagraoui, Nadine Mayotte, Guy Sauvageau

Blood (2023) 142 (Supplement 1): 2681.

https://doi.org/10.1182/blood-2023-189646

Published: 2023

Journal Articles

Deep Multi-Omics Profiling in Cytogenetically Poor-Risk AML

Blood (2022) 140 (Supplement 1): 1030–1032.

https://doi.org/10.1182/blood-2022-159069

Published: 2022

Journal Articles

The EBMT Disease Risk Stratification System (DRSS) Allows Prediction of Relapse after Allogeneic Hematopoietic Cell Transplantation for Acute Myeloid Leukemia and Myelodysplastic Syndrome

Yasmine Kadri, Michelle Phan, Nadia Bambace, Léa Bernard, Sandra Cohen, Jean-Sébastien Delisle, Thomas L. Kiss, Sylvia Lachance, Denis-Claude Roy, Jean Roy, Guy Sauvageau, Olivier Veilleux, Imran Ahmad

Blood (2022) 140 (Supplement 1): 7759–7760.

https://doi.org/10.1182/blood-2022-157107

Published: 2022

Journal Articles

Improved Outcomes of UM171-Expanded Cord Blood Transplantation Compared with Other Graft Sources: Real World Evidence

Sandra Cohen, Nadia M. Bambace, Imran Ahmad, Linda J. Burns, Jean Roy, Silvy Lachance, Léa Bernard, Jean-Sébastien Delisle, Denis-Claude Roy, Thomas L. Kiss, Olivier Veilleux, Mei-Jie Zhang, Xiao-Ying Tang, Guy Sauvageau

Blood (2022) 140 (Supplement 1): 1610–1612.

https://doi.org/10.1182/blood-2022-160417

Published: 2022

Journal Articles

Targeting PLZF Enhances Glucocorticoid Sensitivity in Acute Myeloid Leukemia

Azadeh Hajmirza, Laura Simon, Jalila Chagraoui, Nadine Mayotte, Jean-François Spinella, Tara Macrae, Bernhard Lehnertz, Thierry Bertomeu, Jasmin Coulombe-Huntington, Geneviève Boucher, Sébastien Lemieux, Mike Tyers, Josee Hebert, Guy Sauvageau

Blood (2022) 140 (Supplement 1): 8825–8826.

https://doi.org/10.1182/blood-2022-163685

Published: 2022

Journal Articles

Identification of a Novel Cyclin K Degrader Molecule with Selective Anti-AML Activity

Deanne Gracias, Céline Moison, Rodrigo Mendoza-Sanchez, Simon Fortier, Simon Girard, Jean-Francois Spinella, Tara Macrae, Bounkham Thavonekham, Rejean Ruel, Josee Hebert, Anne Marinier, Guy Sauvageau

Blood (2022) 140 (Supplement 1): 10684.

https://doi.org/10.1182/blood-2022-166517

Published: 2022

Journal Articles

Ex Vivo Generation and Infusion of Anti-Minor Histocompatibility Antigen Expanded T Cells for Patients Who Relapse after Allogeneic HLA-Matched Stem Cell Transplantation

Blood (2022) 140 (Supplement 1): 1601–1603.

https://doi.org/10.1182/blood-2022-170147

Published: 2022

Journal Articles

Disruption of Intracellular Metal Homeostasis As a Vulnerability in SF3B1 Mutated AML

Céline Moison, Deanne Gracias, Julie Schmitt, Simon Girard, Simon Fortier, Isabel Boivin, Jean-Francois Spinella, Tara Macrae, Rejean Ruel, Josee Hebert, Anne Marinier, Guy Sauvageau

Blood (2022) 140 (Supplement 1): 10680–10681.

https://doi.org/10.1182/blood-2022-165235

Published: 2022

Journal Articles

Identification of Novel Antigens for Normal Karyotype Triple Mutated Acute Myeloid Leukemia

Arnaud Metois, Marie-Eve Bordeleau, Louis Theret, Azadeh Hajmirza, Ossama Moujaber, Jean-François Spinella, Jalila Chagraoui, Nadine Mayotte, Isabel Boivin, Eric Audemard, Azer Farah, Véronique Lisi, Eric Bonneil, Pierre Thibault, Guillaume Richard-Carpentier, Vincent-Philippe Lavallée, Josee Hebert, Philippe P Roux, Guy Sauvageau

Blood (2022) 140 (Supplement 1): 11791–11792.

https://doi.org/10.1182/blood-2022-166857

Published: 2022

Journal Articles

Identification of Novel Cell Surface Therapeutic Targets for KMT2A -Rearranged Acute Myeloid Leukemia

Blood (2022) 140 (Supplement 1): 6316–6317.

https://doi.org/10.1182/blood-2022-166769

Published: 2022

Journal Articles

IL1R1 Expression Predicts the Benefit from Allogeneic Hematopoietic Stem Cell Transplantation in Patients with Acute Myeloid Leukemia and Intermediate-Risk Cytogenetics

Guillaume Richard-Carpentier, Francois Beliveau, Sandrine Lacoste, Jean-Francois Spinella, Michael Vladovsky, Patrick Gendron, Sébastien Lemieux, Vincent-Philippe Lavallee, Guy Sauvageau, Josee Hebert

Blood (2022) 140 (Supplement 1): 6333–6334.

https://doi.org/10.1182/blood-2022-170230

Published: 2022

Journal Articles

HLF expression defines the human hematopoietic stem cell state

Bernhard Lehnertz, Jalila Chagraoui, Tara MacRae, Elisa Tomellini, Sophie Corneau, Nadine Mayotte, Isabel Boivin, Aurélie Durand, Deanne Gracias, Guy Sauvageau

Blood (2021) 138 (25): 2642–2654.

https://doi.org/10.1182/blood.2021010745

Published: 2021

Includes: Supplemental data

Journal Articles

UM171-Expanded Cord Blood Transplants Support Robust T-Cell Reconstitution with Low Rates of Severe Infections

Blood (2020) 136 (Supplement 1): 36–37.

https://doi.org/10.1182/blood-2020-139598

Published: 2020

Journal Articles

High frequency of germline RUNX1 mutations in patients with RUNX1 -mutated AML

Laura Simon, Jean-François Spinella, Chi-Yuan Yao, Vincent-Philippe Lavallée, Isabel Boivin, Geneviève Boucher, Eric Audemard, Marie-Eve Bordeleau, Sébastien Lemieux, Josée Hébert, Guy Sauvageau

Blood (2020) 135 (21): 1882–1886.

https://doi.org/10.1182/blood.2019003357

Published: 2020

Includes: Supplemental data

Journal Articles

A 9-Gene Expression Signature Identifies Patients with Core-Binding Factor Acute Myeloid Leukemia at High Risk of Relapse after Achieving Complete Remission

Guillaume Richard-Carpentier, MD, Miriam Marquis, PhD, Francois Beliveau, PhD, Guy Sauvageau, MD PhD, Josee Hebert, MD

Blood (2019) 134 (Supplement_1): 1432.

https://doi.org/10.1182/blood-2019-129990

Published: 2019

NARROW

KBTBD4-mediated reduction of MYC is critical for hematopoietic stem cell expansion upon UM171 treatment

Identification of Acute Myeloid Leukemia Cell Surface Therapeutic Targets Using Single Cell RNA Sequencing Supported By Surface Proteomics

UM171 Enhances Fitness and Engraftment of Gene Modified Hematopoietic Stem Cells from Sickle Cells Disease Patients

Infusion of UM171-Expanded Cord Blood Led to Excellent Survival in Patients with High-Risk Leukemias: Results from Two Independent Phase II Studies

The XPO1-FOXC1-HOX Functional Axis Opens New Therapeutic Avenues to Treat DEK-NUP214 AML Patients

Deciphering the Boundaries of KBTBD4-CoREST1 Axis Modulation to Maximally Expand Human HSCs

Deep Multi-Omics Profiling in Cytogenetically Poor-Risk AML

The EBMT Disease Risk Stratification System (DRSS) Allows Prediction of Relapse after Allogeneic Hematopoietic Cell Transplantation for Acute Myeloid Leukemia and Myelodysplastic Syndrome

Improved Outcomes of UM171-Expanded Cord Blood Transplantation Compared with Other Graft Sources: Real World Evidence

Targeting PLZF Enhances Glucocorticoid Sensitivity in Acute Myeloid Leukemia

Identification of a Novel Cyclin K Degrader Molecule with Selective Anti-AML Activity

Ex Vivo Generation and Infusion of Anti-Minor Histocompatibility Antigen Expanded T Cells for Patients Who Relapse after Allogeneic HLA-Matched Stem Cell Transplantation

Disruption of Intracellular Metal Homeostasis As a Vulnerability in SF3B1 Mutated AML

Identification of Novel Antigens for Normal Karyotype Triple Mutated Acute Myeloid Leukemia

Identification of Novel Cell Surface Therapeutic Targets for KMT2A -Rearranged Acute Myeloid Leukemia

IL1R1 Expression Predicts the Benefit from Allogeneic Hematopoietic Stem Cell Transplantation in Patients with Acute Myeloid Leukemia and Intermediate-Risk Cytogenetics

HLF expression defines the human hematopoietic stem cell state

UM171-Expanded Cord Blood Transplants Support Robust T-Cell Reconstitution with Low Rates of Severe Infections

High frequency of germline RUNX1 mutations in patients with RUNX1 -mutated AML

A 9-Gene Expression Signature Identifies Patients with Core-Binding Factor Acute Myeloid Leukemia at High Risk of Relapse after Achieving Complete Remission

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American Society of Hematology

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ASH Publications

American Society of Hematology

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