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Journal Articles

KBTBD4-mediated reduction of MYC is critical for hematopoietic stem cell expansion upon UM171 treatment

Jalila Chagraoui, Simon Girard, Laure Mallinger, Nadine Mayotte, Maria Florencia Tellechea, Guy Sauvageau

Blood (2024) 143 (10): 882–894.

https://doi.org/10.1182/blood.2023021342

Published: 2024

Includes: Supplemental data

Journal Articles

Identification of Acute Myeloid Leukemia Cell Surface Therapeutic Targets Using Single Cell RNA Sequencing Supported By Surface Proteomics

Blood (2023) 142 (Supplement 1): 163.

https://doi.org/10.1182/blood-2023-186367

Published: 2023

Journal Articles

Deciphering the Boundaries of KBTBD4-CoREST1 Axis Modulation to Maximally Expand Human HSCs

Maria Florencia Florencia Tellechea, Jalila Chagraoui, Nadine Mayotte, Guy Sauvageau

Blood (2023) 142 (Supplement 1): 2681.

https://doi.org/10.1182/blood-2023-189646

Published: 2023

Journal Articles

Identification of Novel Antigens for Normal Karyotype Triple Mutated Acute Myeloid Leukemia

Arnaud Metois, Marie-Eve Bordeleau, Louis Theret, Azadeh Hajmirza, Ossama Moujaber, Jean-François Spinella, Jalila Chagraoui, Nadine Mayotte, Isabel Boivin, Eric Audemard, Azer Farah, Véronique Lisi, Eric Bonneil, Pierre Thibault, Guillaume Richard-Carpentier, Vincent-Philippe Lavallée, Josee Hebert, Philippe P Roux, Guy Sauvageau

Blood (2022) 140 (Supplement 1): 11791–11792.

https://doi.org/10.1182/blood-2022-166857

Published: 2022

Journal Articles

Identification of Novel Cell Surface Therapeutic Targets for KMT2A -Rearranged Acute Myeloid Leukemia

Blood (2022) 140 (Supplement 1): 6316–6317.

https://doi.org/10.1182/blood-2022-166769

Published: 2022

Journal Articles

Targeting PLZF Enhances Glucocorticoid Sensitivity in Acute Myeloid Leukemia

Azadeh Hajmirza, Laura Simon, Jalila Chagraoui, Nadine Mayotte, Jean-François Spinella, Tara Macrae, Bernhard Lehnertz, Thierry Bertomeu, Jasmin Coulombe-Huntington, Geneviève Boucher, Sébastien Lemieux, Mike Tyers, Josee Hebert, Guy Sauvageau

Blood (2022) 140 (Supplement 1): 8825–8826.

https://doi.org/10.1182/blood-2022-163685

Published: 2022

Journal Articles

HLF expression defines the human hematopoietic stem cell state

Bernhard Lehnertz, Jalila Chagraoui, Tara MacRae, Elisa Tomellini, Sophie Corneau, Nadine Mayotte, Isabel Boivin, Aurélie Durand, Deanne Gracias, Guy Sauvageau

Blood (2021) 138 (25): 2642–2654.

https://doi.org/10.1182/blood.2021010745

Published: 2021

Includes: Supplemental data

Journal Articles

Mubritinib Targets the Electron Transport Chain Complex I and Reveals the Landscape of Mitochondrial Vulnerability in Acute Myeloid Leukemia

Blood (2018) 132 (Supplement 1): 910.

https://doi.org/10.1182/blood-2018-99-114525

Published: 2018

Journal Articles

Coordination of Pro- and Anti-Inflammatory Signals Determine Human Hematopoietic Stem and Progenitor Cell Expansion

Jalila Chagraoui, PhD, Elisa Tomellini, PhD, Leo Aubert, Iman Fares, PhD, Jean-Francois Spinella, PhD, Simon Girard, Nadine Mayotte, Philippe P Roux, PhD, Guy Sauvageau, MD, PhD

Blood (2018) 132 (Supplement 1): 2555.

https://doi.org/10.1182/blood-2018-99-111917

Published: 2018

Journal Articles

Integrin-α3 Is a New Marker of Long-Term Hematopoietic Stem Cells in Ex Vivo Expanded Cells

Elisa Tomellini, PhD, Iman Fares, PhD, Bernhard Lehnertz, PhD, Jalila Chagraoui, PhD, Nadine Mayotte, Tara MacRae, Sophie Corneau, Guy Sauvageau, MD, PhD

Blood (2018) 132 (Supplement 1): 1267.

https://doi.org/10.1182/blood-2018-99-111963

Published: 2018

Journal Articles

H3K27M/I Mutations Promote Context-Dependent Transformation in Acute Myeloid Leukemia with RUNX1 Alterations

Bernhard Lehnertz, PhD, Yu Wei Zhang, Isabel Boivin, Nadine Mayotte, Tomellini Elisa, PhD, Jalila Chagraoui, PhD, Vincent-Philippe Lavallée, MD, Josée Hébert, MD, Guy Sauvageau, MD, PhD

Blood (2017) 130 (Supplement 1): 302.

https://doi.org/10.1182/blood.V130.Suppl_1.302.302

Published: 2017

Journal Articles

H3 K27M/I mutations promote context-dependent transformation in acute myeloid leukemia with RUNX1 alterations

Bernhard Lehnertz, Yu Wei Zhang, Isabel Boivin, Nadine Mayotte, Elisa Tomellini, Jalila Chagraoui, Vincent-Philippe Lavallée, Josée Hébert, Guy Sauvageau

Blood (2017) 130 (20): 2204–2214.

https://doi.org/10.1182/blood-2017-03-774653

Published: 2017

Includes: Supplemental data

Journal Articles

EPCR expression marks UM171-expanded CD34 + cord blood stem cells

Iman Fares, Jalila Chagraoui, Bernhard Lehnertz, Tara MacRae, Nadine Mayotte, Elisa Tomellini, Léo Aubert, Philippe P. Roux, Guy Sauvageau

Blood (2017) 129 (25): 3344–3351.

https://doi.org/10.1182/blood-2016-11-750729

Published: 2017

Includes: Supplemental data

Journal Articles

Pyrimido-Indole Derivatives Are Novel Agonists of Human Cord Blood Hematopoietic Stem Cell Self-Renewal

Iman Fares, Jalila Chagaroui, Yves Gareau, Stéphane Gingras, Nadine Mayotte, Elizabeth Csaszar, Hans-Peter Kiem, Norman N. Iscove, R. Keith Humphries, Connie J. Eaves, Sandra Cohen, Anne Marinier, PhD, Peter W. Zandstra, Guy Sauvageau, MD PhD

Blood (2014) 124 (21): 650.

https://doi.org/10.1182/blood.V124.21.650.650

Published: 2014

Journal Articles

UBAP2L is a novel BMI1-interacting protein essential for hematopoietic stem cell activity

Marie-Eve Bordeleau, Romain Aucagne, Jalila Chagraoui, Simon Girard, Nadine Mayotte, Éric Bonneil, Pierre Thibault, Caroline Pabst, Anne Bergeron, Frédéric Barabé, Josée Hébert, Martin Sauvageau, Christel Boutonnet, Sylvain Meloche, Guy Sauvageau

Blood (2014) 124 (15): 2362–2369.

https://doi.org/10.1182/blood-2014-01-548651

Published: 2014

Includes: Supplemental data

Journal Articles

RNAi screen identifies Jarid1b as a major regulator of mouse HSC activity

Sonia Cellot, Kristin J. Hope, Jalila Chagraoui, Martin Sauvageau, Éric Deneault, Tara MacRae, Nadine Mayotte, Brian T. Wilhelm, Josette R. Landry, Stephen B. Ting, Jana Krosl, Keith Humphries, Alexander Thompson, Guy Sauvageau

Blood (2013) 122 (9): 1545–1555.

https://doi.org/10.1182/blood-2013-04-496281

Published: 2013

Includes: Supplemental data

Journal Articles

Posttranslational regulation of self-renewal capacity: insights from proteome and phosphoproteome analyses of stem cell leukemia

Matthias Trost, Martin Sauvageau, Olivier Hérault, Paul Deleris, Christelle Pomiès, Jalila Chagraoui, Nadine Mayotte, Sylvain Meloche, Guy Sauvageau, Pierre Thibault

Blood (2012) 120 (8): e17–e27.

https://doi.org/10.1182/blood-2011-12-397844

Published: 2012

Includes: Supplemental data

Journal Articles

Asymmetric segregation and self-renewal of hematopoietic stem and progenitor cells with endocytic Ap2a2

Stephen B. Ting, Eric Deneault, Kristin Hope, Sonia Cellot, Jalila Chagraoui, Nadine Mayotte, Jonas F. Dorn, Jean-Philippe Laverdure, Michael Harvey, Edwin D. Hawkins, Sarah M. Russell, Paul S. Maddox, Norman N. Iscove, Guy Sauvageau

Blood (2012) 119 (11): 2510–2522.

https://doi.org/10.1182/blood-2011-11-393272

Published: 2012

Includes: Multimedia, Supplemental data

Journal Articles

Identification of Lats 1 As a Putative Tumor Suppressor in HoxA9/Meis Induced Leukemia

Eva Schmidt, MD, Jana Krosl, PhD, Jalila Chagraoui, PhD, Nadine Mayotte, Caroline Pabst, MD, Tara McRae, Guy Sauvageau, MD, PhD

Blood (2011) 118 (21): 2474.

https://doi.org/10.1182/blood.V118.21.2474.2474

Published: 2011

Journal Articles

A Functional In Vivo RNAi screen Involving Jumonji C Domain Containing Candidates Unravels Kdm5b As a Negative Modulator of Hematopoietic Stem Cell Self-Renewal

Sonia Cellot, MD, Kristin J Hope, PhD, Martin Sauvageau, PhD, Jalila Chagraoui, PhD, Eric Deneault, PhD, Tara MacRae, Nadine Mayotte, Guy Sauvageau, MD, PhD

Blood (2011) 118 (21): 385.

https://doi.org/10.1182/blood.V118.21.385.385

Published: 2011

NARROW

KBTBD4-mediated reduction of MYC is critical for hematopoietic stem cell expansion upon UM171 treatment

Identification of Acute Myeloid Leukemia Cell Surface Therapeutic Targets Using Single Cell RNA Sequencing Supported By Surface Proteomics

Deciphering the Boundaries of KBTBD4-CoREST1 Axis Modulation to Maximally Expand Human HSCs

Identification of Novel Antigens for Normal Karyotype Triple Mutated Acute Myeloid Leukemia

Identification of Novel Cell Surface Therapeutic Targets for KMT2A -Rearranged Acute Myeloid Leukemia

Targeting PLZF Enhances Glucocorticoid Sensitivity in Acute Myeloid Leukemia

HLF expression defines the human hematopoietic stem cell state

Mubritinib Targets the Electron Transport Chain Complex I and Reveals the Landscape of Mitochondrial Vulnerability in Acute Myeloid Leukemia

Coordination of Pro- and Anti-Inflammatory Signals Determine Human Hematopoietic Stem and Progenitor Cell Expansion

Integrin-α3 Is a New Marker of Long-Term Hematopoietic Stem Cells in Ex Vivo Expanded Cells

H3K27M/I Mutations Promote Context-Dependent Transformation in Acute Myeloid Leukemia with RUNX1 Alterations

H3 K27M/I mutations promote context-dependent transformation in acute myeloid leukemia with RUNX1 alterations

EPCR expression marks UM171-expanded CD34 + cord blood stem cells

Pyrimido-Indole Derivatives Are Novel Agonists of Human Cord Blood Hematopoietic Stem Cell Self-Renewal

UBAP2L is a novel BMI1-interacting protein essential for hematopoietic stem cell activity

RNAi screen identifies Jarid1b as a major regulator of mouse HSC activity

Posttranslational regulation of self-renewal capacity: insights from proteome and phosphoproteome analyses of stem cell leukemia

Asymmetric segregation and self-renewal of hematopoietic stem and progenitor cells with endocytic Ap2a2

Identification of Lats 1 As a Putative Tumor Suppressor in HoxA9/Meis Induced Leukemia

A Functional In Vivo RNAi screen Involving Jumonji C Domain Containing Candidates Unravels Kdm5b As a Negative Modulator of Hematopoietic Stem Cell Self-Renewal

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American Society of Hematology

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American Society of Hematology

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