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Journal Articles

Targeting PLZF Enhances Glucocorticoid Sensitivity in Acute Myeloid Leukemia

Azadeh Hajmirza, Laura Simon, Jalila Chagraoui, Nadine Mayotte, Jean-François Spinella, Tara Macrae, Bernhard Lehnertz, Thierry Bertomeu, Jasmin Coulombe-Huntington, Geneviève Boucher, Sébastien Lemieux, Mike Tyers, Josee Hebert, Guy Sauvageau

Blood (2022) 140 (Supplement 1): 8825–8826.

https://doi.org/10.1182/blood-2022-163685

Published: 2022

Journal Articles

Identification of a Novel Cyclin K Degrader Molecule with Selective Anti-AML Activity

Deanne Gracias, Céline Moison, Rodrigo Mendoza-Sanchez, Simon Fortier, Simon Girard, Jean-Francois Spinella, Tara Macrae, Bounkham Thavonekham, Rejean Ruel, Josee Hebert, Anne Marinier, Guy Sauvageau

Blood (2022) 140 (Supplement 1): 10684.

https://doi.org/10.1182/blood-2022-166517

Published: 2022

Journal Articles

Disruption of Intracellular Metal Homeostasis As a Vulnerability in SF3B1 Mutated AML

Céline Moison, Deanne Gracias, Julie Schmitt, Simon Girard, Simon Fortier, Isabel Boivin, Jean-Francois Spinella, Tara Macrae, Rejean Ruel, Josee Hebert, Anne Marinier, Guy Sauvageau

Blood (2022) 140 (Supplement 1): 10680–10681.

https://doi.org/10.1182/blood-2022-165235

Published: 2022

Journal Articles

Identification of Novel Cell Surface Therapeutic Targets for KMT2A -Rearranged Acute Myeloid Leukemia

Blood (2022) 140 (Supplement 1): 6316–6317.

https://doi.org/10.1182/blood-2022-166769

Published: 2022

Journal Articles

HLF expression defines the human hematopoietic stem cell state

Bernhard Lehnertz, Jalila Chagraoui, Tara MacRae, Elisa Tomellini, Sophie Corneau, Nadine Mayotte, Isabel Boivin, Aurélie Durand, Deanne Gracias, Guy Sauvageau

Blood (2021) 138 (25): 2642–2654.

https://doi.org/10.1182/blood.2021010745

Published: 2021

Includes: Supplemental data

Journal Articles

Mubritinib Targets the Electron Transport Chain Complex I and Reveals the Landscape of Mitochondrial Vulnerability in Acute Myeloid Leukemia

Blood (2018) 132 (Supplement 1): 910.

https://doi.org/10.1182/blood-2018-99-114525

Published: 2018

Journal Articles

Chemogenomic Approach Unveils the Increased Susceptibility of RUNX1 -Mutated AML to Glucocorticoids

Laura Simon, BSc, MSc, Vincent-Philippe Lavallee, MD, Marie-Eve Bordeleau, PhD, Bernhard Lehnertz, PhD, Tara MacRae, Jalila Chagraoui, PhD, Jean-Francois Spinella, PhD, Geneviève Boucher, Thierry Bertomeu, PhD, Jasmin Coulombe-Huntington, PhD, Mike Tyers, PhD, Sébastien Lemieux, PhD, Anne Marinier, PhD, Josée Hébert, MD, Guy Sauvageau, MD PhD

Blood (2018) 132 (Supplement 1): 4675.

https://doi.org/10.1182/blood-2018-99-111030

Published: 2018

Journal Articles

Integrin-α3 Is a New Marker of Long-Term Hematopoietic Stem Cells in Ex Vivo Expanded Cells

Elisa Tomellini, PhD, Iman Fares, PhD, Bernhard Lehnertz, PhD, Jalila Chagraoui, PhD, Nadine Mayotte, Tara MacRae, Sophie Corneau, Guy Sauvageau, MD, PhD

Blood (2018) 132 (Supplement 1): 1267.

https://doi.org/10.1182/blood-2018-99-111963

Published: 2018

Journal Articles

Genetic Characterization of ABT-199 Sensitivity in Human AML

Marie-Eve Bordeleau, PhD, Richard Bisaillon, PhD, Clarisse Thiollier, PhD, Jana Krosl, PhD, Bernhard Lehnertz, PhD, Vincent-Philippe Lavallee, MD, Tara MacRae, Labelle Caroline, Geneviève Boucher, Isabel Boivin, Giovanni D'Angelo, Sylvie Lavallée, Anne Marinier, PhD, Sébastien Lemieux, PhD, Josée Hébert, MD, Guy Sauvageau, MD, PhD

Blood (2018) 132 (Supplement 1): 283.

https://doi.org/10.1182/blood-2018-99-113062

Published: 2018

Journal Articles

EPCR expression marks UM171-expanded CD34 + cord blood stem cells

Iman Fares, Jalila Chagraoui, Bernhard Lehnertz, Tara MacRae, Nadine Mayotte, Elisa Tomellini, Léo Aubert, Philippe P. Roux, Guy Sauvageau

Blood (2017) 129 (25): 3344–3351.

https://doi.org/10.1182/blood-2016-11-750729

Published: 2017

Includes: Supplemental data

Journal Articles

Modeling of Pediatric Acute Megakaryoblastic Leukemia Using Cord Blood Stem/Progenitor Cells

Sophie Cardin, PhD, Louise Laramee, Tara MacRae, M.Sc., Jalila Chagraoui, PhD, Guy Sauvageau, MD PhD, R. Keith Humphries, MD PhD, Josée Hébert, MD, Brian T. Wilhelm, PhD, Sonia Cellot, MD PhD

Blood (2016) 128 (22): 1535.

https://doi.org/10.1182/blood.V128.22.1535.1535

Published: 2016

Journal Articles

Transcriptional Landscape of APL Identifies Aberrant Podoplanin Expression As a Defining Feature and Missing Link for the Bleeding Disorder of This Disease

Vincent-Philippe Lavallée, MD, Miriam Marquis, PhD, Marie-Ève Bordeleau, PhD, Jalila Chagraoui, PhD, Tara MacRae, M.Sc., Isabel Boivin, M.Sc, Geneviève Boucher, M.Sc, Patrick Gendron, M.Sc, Sébastien Lemieux, PhD, Arnaud Bonnefoy, PhD, Georges E. Rivard, MD, Josée Hébert, MD, Guy Sauvageau, MD, PhD

Blood (2016) 128 (22): 1075.

https://doi.org/10.1182/blood.V128.22.1075.1075

Published: 2016

Journal Articles

RNAi screen identifies Jarid1b as a major regulator of mouse HSC activity

Sonia Cellot, Kristin J. Hope, Jalila Chagraoui, Martin Sauvageau, Éric Deneault, Tara MacRae, Nadine Mayotte, Brian T. Wilhelm, Josette R. Landry, Stephen B. Ting, Jana Krosl, Keith Humphries, Alexander Thompson, Guy Sauvageau

Blood (2013) 122 (9): 1545–1555.

https://doi.org/10.1182/blood-2013-04-496281

Published: 2013

Includes: Supplemental data

Journal Articles

A Functional In Vivo RNAi screen Involving Jumonji C Domain Containing Candidates Unravels Kdm5b As a Negative Modulator of Hematopoietic Stem Cell Self-Renewal

Sonia Cellot, MD, Kristin J Hope, PhD, Martin Sauvageau, PhD, Jalila Chagraoui, PhD, Eric Deneault, PhD, Tara MacRae, Nadine Mayotte, Guy Sauvageau, MD, PhD

Blood (2011) 118 (21): 385.

https://doi.org/10.1182/blood.V118.21.385.385

Published: 2011

NARROW

Targeting PLZF Enhances Glucocorticoid Sensitivity in Acute Myeloid Leukemia

Identification of a Novel Cyclin K Degrader Molecule with Selective Anti-AML Activity

Disruption of Intracellular Metal Homeostasis As a Vulnerability in SF3B1 Mutated AML

Identification of Novel Cell Surface Therapeutic Targets for KMT2A -Rearranged Acute Myeloid Leukemia

HLF expression defines the human hematopoietic stem cell state

Mubritinib Targets the Electron Transport Chain Complex I and Reveals the Landscape of Mitochondrial Vulnerability in Acute Myeloid Leukemia

Chemogenomic Approach Unveils the Increased Susceptibility of RUNX1 -Mutated AML to Glucocorticoids

Integrin-α3 Is a New Marker of Long-Term Hematopoietic Stem Cells in Ex Vivo Expanded Cells

Genetic Characterization of ABT-199 Sensitivity in Human AML

EPCR expression marks UM171-expanded CD34 + cord blood stem cells

Modeling of Pediatric Acute Megakaryoblastic Leukemia Using Cord Blood Stem/Progenitor Cells

Transcriptional Landscape of APL Identifies Aberrant Podoplanin Expression As a Defining Feature and Missing Link for the Bleeding Disorder of This Disease

RNAi screen identifies Jarid1b as a major regulator of mouse HSC activity

A Functional In Vivo RNAi screen Involving Jumonji C Domain Containing Candidates Unravels Kdm5b As a Negative Modulator of Hematopoietic Stem Cell Self-Renewal

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American Society of Hematology

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ASH Publications

American Society of Hematology

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