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Alexander Thompson
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Journal Articles

Prothrombotic Antibodies Targeting the Spike Protein's Receptor-Binding Domain in Severe COVID-19

Wen Zhu, Yongwei Zheng, Mei Yu, Nathan Witman, Lu Zhou, Jianhui Wei, Yongguang Zhang, Paytsar Topchyan, Christine Nguyen, David Wang, Rae Janecke, Anand Padmanabhan, Lisa Baumann Kreuziger, Gilbert C White, Parameswaran Hari, Tongjun Gu, Alexander Thompson Fields, Lucy Kornblith, Richard H Aster, Jieqing Zhu, Weiguo Cui, Shawn M Jobe, Mary Beth Graham, Demin Wang, Renren Wen
Journal: Blood
Blood blood.2024025010.
https://doi.org/10.1182/blood.2024025010
Published: 2024
Includes: Supplemental data
Journal Articles

High-Throughput Screen Identification of Albendazole As a Novel Repurposed Drug in Acute Myeloid Leukaemia

Kyle B Matchett, PhD, Ivan V Grishagin, PhD, Laura Kettyle, PhD, Catriona Dowling, PhD, Triona Ni Chonghaile, PhD, Ken I Mills, BSc PhDFRCPath, Alexander Thompson, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 5062.
https://doi.org/10.1182/blood.V130.Suppl_1.5062.5062
Published: 2017
Journal Articles

Loss of Function Cohesin Complex Gene Mutations Create Neomorphic Cell States Advantageous to Oncogenesis

James S Smith, BSc (Hons), Kienan I Savage, PhD, Alexander Thompson, PhD, Ken I Mills, PhD, FRCPath
Journal: Blood
Blood (2016) 128 (22): 1564.
https://doi.org/10.1182/blood.V128.22.1564.1564
Published: 2016
Journal Articles

Hoxa cluster genes determine the proliferative activity of adult mouse hematopoietic stem and progenitor cells

Brief Report
Charles-Étienne Lebert-Ghali, Marilaine Fournier, Laura Kettyle, Alexander Thompson, Guy Sauvageau, Janet J. Bijl
Journal: Blood
Blood (2016) 127 (1): 87–90.
https://doi.org/10.1182/blood-2015-02-626390
Published: 2016
Includes: Supplemental data
Journal Articles

Conditional Deletion of the Hoxa Cluster in MLL-AF9 Is Incompatible with Leukemia Maintenance

Laura M Kettyle, BSc, Ivan Grishagin, PhD, Glenda J Dickson, PhD, Charles-Etienne Lebert-Ghali, PhD, Janetta Jacoba Bijl, PhD, Mary Frances McMullin, MD FRCPath, FRCP, Terence R.J. Lappin, PhD FRCPath, Ken I Mills, PhD, FRCPath, Alexander Thompson, PhD
Journal: Blood
Blood (2015) 126 (23): 3630.
https://doi.org/10.1182/blood.V126.23.3630.3630
Published: 2015
Journal Articles

RNAi screen identifies Jarid1b as a major regulator of mouse HSC activity

Sonia Cellot, Kristin J. Hope, Jalila Chagraoui, Martin Sauvageau, Éric Deneault, Tara MacRae, Nadine Mayotte, Brian T. Wilhelm, Josette R. Landry, Stephen B. Ting, Jana Krosl, Keith Humphries, Alexander Thompson, Guy Sauvageau
Journal: Blood
Blood (2013) 122 (9): 1545–1555.
https://doi.org/10.1182/blood-2013-04-496281
Published: 2013
Includes: Supplemental data
Journal Articles

Therapeutic Potential of Targeted HOXA-TALE Knockdown in AML,

Glenda Joanne Dickson, PhD, Kathleen A O'Hagan, PhD, Damian PJ Finnegan, MRCP, FRCPath, PhD, Mary Frances McMullin, MD, Ken I. Mills, PhD, FRCPath, Terence R.J. Lappin, PhD, FRCPath, Alexander Thompson, BSc, MSc, PhD
Journal: Blood
Blood (2011) 118 (21): 3460.
https://doi.org/10.1182/blood.V118.21.3460.3460
Published: 2011
Journal Articles

Differential Gene and MicroRNA Expression In a HOXA9-MEIS1 Model of Leukemia

Joanne Margaret Ramsey, BSc, Glenda Joanne Dickson, PhD, Janetta Jacoba Bijl, PhD, Ken I. Mills, PhD, FRCPath, Terence R.J. Lappin, PhD, FRCPath, Guy Sauvageau, MD, PhD, FRCPC, Alexander Thompson, PhD
Journal: Blood
Blood (2010) 116 (21): 64.
https://doi.org/10.1182/blood.V116.21.64.64
Published: 2010
Journal Articles

Analysis of HOXA5 and HOXB3 Expression Complements Conventional Cytogenetic Analysis in Acute Myeloid Leukemia.

Damian P.J. Finnegan, MRCP(UK), Vivien M. Hodges, PhD, Alexander Thompson, PhD, Michael F. Quinn, MD, Mervyn Humphries, PhD, Terence R.J. Lappin, PhD, Mary Frances McMullin, MD, Graham R. Ball, PhD
Journal: Blood
Blood (2007) 110 (11): 2388.
https://doi.org/10.1182/blood.V110.11.2388.2388
Published: 2007
Journal Articles

Artificial Neural Network Analysis of HOX Gene Expression Profiles Predicts Prognostic Subgroups in Acute Myeloid Leukemia.

Damian P.J. Finnegan, MRCP (UK), Michael F. Quinn, MD, Mervyn Humphreys, PhD, Terence R.J. Lappin, PhD, Mary Frances McMullin, MD, Alexander Thompson, PhD, Graham R. Ball, PhD
Journal: Blood
Blood (2006) 108 (11): 2318.
https://doi.org/10.1182/blood.V108.11.2318.2318
Published: 2006
Journal Articles

HOXA6 : A Novel Candidate Gene in AML.

Glenda J. McGonigle, PhD, Damian P.J. Finnegan, MB, Mary Frances McMullin, MD, Terence R.J. Lappin, PhD, Alexander Thompson, PhD
Journal: Blood
Blood (2006) 108 (11): 2312.
https://doi.org/10.1182/blood.V108.11.2312.2312
Published: 2006
Journal Articles

Molecular dissection of Meis1 reveals 2 domains required for leukemia induction and a key role for Hoxa gene activation

Aline Mamo, Jana Krosl, Evert Kroon, Janet Bijl, Alexander Thompson, Nadine Mayotte, Simon Girard, Richard Bisaillon, Nathalie Beslu, Mark Featherstone, Guy Sauvageau
Journal: Blood
Blood (2006) 108 (2): 622–629.
https://doi.org/10.1182/blood-2005-06-2244
Published: 2006
Includes: Supplemental data
Journal Articles

Analysis of HSC activity and compensatory Hox gene expression profile in Hoxb cluster mutant fetal liver cells

Janet Bijl, Alexander Thompson, Ramiro Ramirez-Solis, Jana Krosl, David G. Grier, H. Jeffrey Lawrence, Guy Sauvageau
Journal: Blood
Blood (2006) 108 (1): 116–122.
https://doi.org/10.1182/blood-2005-06-2245
Published: 2006
Includes: Supplemental data
Journal Articles

Global down-regulation of HOX gene expression in PML-RARα + acute promyelocytic leukemia identified by small-array real-time PCR

Alexander Thompson, Michael F. Quinn, David Grimwade, Claire M. O'Neill, Momin R. Ahmed, Sean Grimes, Mary Frances McMullin, Finbarr Cotter, Terence R. J. Lappin
Journal: Blood
Blood (2003) 101 (4): 1558–1565.
https://doi.org/10.1182/blood.V101.4.1558
Published: 2003