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Journal Articles

Identification of Acute Myeloid Leukemia Cell Surface Therapeutic Targets Using Single Cell RNA Sequencing Supported By Surface Proteomics

Blood (2023) 142 (Supplement 1): 163.

https://doi.org/10.1182/blood-2023-186367

Published: 2023

Journal Articles

Targeting PLZF Enhances Glucocorticoid Sensitivity in Acute Myeloid Leukemia

Azadeh Hajmirza, Laura Simon, Jalila Chagraoui, Nadine Mayotte, Jean-François Spinella, Tara Macrae, Bernhard Lehnertz, Thierry Bertomeu, Jasmin Coulombe-Huntington, Geneviève Boucher, Sébastien Lemieux, Mike Tyers, Josee Hebert, Guy Sauvageau

Blood (2022) 140 (Supplement 1): 8825–8826.

https://doi.org/10.1182/blood-2022-163685

Published: 2022

Journal Articles

Identification of Novel Cell Surface Therapeutic Targets for KMT2A -Rearranged Acute Myeloid Leukemia

Blood (2022) 140 (Supplement 1): 6316–6317.

https://doi.org/10.1182/blood-2022-166769

Published: 2022

Journal Articles

IL1R1 Expression Predicts the Benefit from Allogeneic Hematopoietic Stem Cell Transplantation in Patients with Acute Myeloid Leukemia and Intermediate-Risk Cytogenetics

Guillaume Richard-Carpentier, Francois Beliveau, Sandrine Lacoste, Jean-Francois Spinella, Michael Vladovsky, Patrick Gendron, Sébastien Lemieux, Vincent-Philippe Lavallee, Guy Sauvageau, Josee Hebert

Blood (2022) 140 (Supplement 1): 6333–6334.

https://doi.org/10.1182/blood-2022-170230

Published: 2022

Journal Articles

UM171-Expanded Cord Blood Transplants Support Robust T-Cell Reconstitution with Low Rates of Severe Infections

Blood (2020) 136 (Supplement 1): 36–37.

https://doi.org/10.1182/blood-2020-139598

Published: 2020

Journal Articles

High frequency of germline RUNX1 mutations in patients with RUNX1 -mutated AML

Laura Simon, Jean-François Spinella, Chi-Yuan Yao, Vincent-Philippe Lavallée, Isabel Boivin, Geneviève Boucher, Eric Audemard, Marie-Eve Bordeleau, Sébastien Lemieux, Josée Hébert, Guy Sauvageau

Blood (2020) 135 (21): 1882–1886.

https://doi.org/10.1182/blood.2019003357

Published: 2020

Includes: Supplemental data

Journal Articles

Hepatic leukemia factor is a novel leukemic stem cell regulator in DNMT3A, NPM1, and FLT3-ITD triple-mutated AML

Blood (2019) 134 (3): 263–276.

https://doi.org/10.1182/blood.2018862383

Published: 2019

Includes: Supplemental data

Journal Articles

Chemogenomic Profiling of Complex Karyotype AML Reveals a Novel Susceptibility to G2/M Checkpoint Inhibition Mediated By HMGA2 Overexpression

Céline Moison, PhD, Vincent-Philippe Lavallee, MD, Clarisse Thiollier, PhD, Jean-Francois Spinella, PhD, Isabel Boivin, Sébastien Lemieux, PhD, Anne Marinier, PhD, Josée Hébert, MD, Guy Sauvageau, MD, PhD

Blood (2018) 132 (Supplement 1): 3925.

https://doi.org/10.1182/blood-2018-99-111304

Published: 2018

Journal Articles

Mubritinib Targets the Electron Transport Chain Complex I and Reveals the Landscape of Mitochondrial Vulnerability in Acute Myeloid Leukemia

Blood (2018) 132 (Supplement 1): 910.

https://doi.org/10.1182/blood-2018-99-114525

Published: 2018

Journal Articles

Chemogenomic Approach Unveils the Increased Susceptibility of RUNX1 -Mutated AML to Glucocorticoids

Laura Simon, BSc, MSc, Vincent-Philippe Lavallee, MD, Marie-Eve Bordeleau, PhD, Bernhard Lehnertz, PhD, Tara MacRae, Jalila Chagraoui, PhD, Jean-Francois Spinella, PhD, Geneviève Boucher, Thierry Bertomeu, PhD, Jasmin Coulombe-Huntington, PhD, Mike Tyers, PhD, Sébastien Lemieux, PhD, Anne Marinier, PhD, Josée Hébert, MD, Guy Sauvageau, MD PhD

Blood (2018) 132 (Supplement 1): 4675.

https://doi.org/10.1182/blood-2018-99-111030

Published: 2018

Journal Articles

Single UM171 Expanded Cord Blood Permits Transplantation of Better HLA Matched Cords with Excellent Gvhd Relapse Free Survival

Blood (2018) 132 (Supplement 1): 4658.

https://doi.org/10.1182/blood-2018-99-110188

Published: 2018

Journal Articles

Genetic Characterization of ABT-199 Sensitivity in Human AML

Marie-Eve Bordeleau, PhD, Richard Bisaillon, PhD, Clarisse Thiollier, PhD, Jana Krosl, PhD, Bernhard Lehnertz, PhD, Vincent-Philippe Lavallee, MD, Tara MacRae, Labelle Caroline, Geneviève Boucher, Isabel Boivin, Giovanni D'Angelo, Sylvie Lavallée, Anne Marinier, PhD, Sébastien Lemieux, PhD, Josée Hébert, MD, Guy Sauvageau, MD, PhD

Blood (2018) 132 (Supplement 1): 283.

https://doi.org/10.1182/blood-2018-99-113062

Published: 2018

Journal Articles

Single UM171 Expanded Cord Blood Transplant Is Feasible, Safe, and Permits Transplantation of Better HLA Matched Cords with Very Low Transplant Related Mortality

Sandra Cohen, MD, Jean Roy, MD, Silvy Lachance, MDFRCPC, Anne Marinier, PhD, Denis-Claude Roy, MD, Jean-Sébastien Delisle, MD PhD, Lambert Busque, MD, Pierre Caudrelier, MD, Fannie Larochelle, Philippe Bouchard, BPharm, Jean Roy, MD, Nadia M. Bambace, MD, Léa Bernard, MD, Thomas L Kiss, MD, Sébastien Lemieux, PhD, Peter W. Zandstra, PhD, Guy Sauvageau, MD, PhD

Blood (2017) 130 (Supplement 1): 658.

https://doi.org/10.1182/blood.V130.Suppl_1.658.658

Published: 2017

Journal Articles

HMGA2 Gene Expression Profile Improves Risk Stratification in Acute Myeloid Leukemia

Miriam Marquis, PhD, Cyrielle Beaubois, Vincent-Philippe Lavallee, MD, Michal Abrahamowicz, PhD, Coraline Danieli, PhD, Sébastien Lemieux, PhD, Imran Ahmad, MD, Andrew Wei, MBBS, FRACP, FRCPA, PhD, Stephen B Ting, MD PhD, Shaun Fleming, MBBS(Hons) FRACP FRCPA, Anthony P Schwarer, MD MBBS (Hons), FRACP, FRCPA, William Grey, PhD, David Grimwade, MD PhD, Robert K. Hills, DPhil, Paresh Vyas, MD PhD, Nigel H. Russell, MD, Guy Sauvageau, MD, PhD, Josee Hebert, MD

Blood (2017) 130 (Supplement 1): 1402.

https://doi.org/10.1182/blood.V130.Suppl_1.1402.1402

Published: 2017

Journal Articles

Podoplanin Expression in the Bleeding Complications of Acute Promyelocytic Leukemias

Vincent-Philippe Lavallee, MD, Jalila Chagraoui, PhD, MacRae Tara, M.Sc., Miriam Marquis, PhD, Bonnefoy Arnaud, PhD, Jana Krosl, PhD, Sébastien Lemieux, PhD, Georges-Étienne Rivard, MD, Josée Hébert, MD, Guy Sauvageau, MD, PhD

Blood (2017) 130 (Supplement 1): 105.

https://doi.org/10.1182/blood.V130.Suppl_1.105.105

Published: 2017

Journal Articles

Prediction of Severe Acute Graft-Versus-Host Disease (aGVHD) Based on Whole Transcriptome Sequencing of Donor CD4 T Cells

Silvy Lachance, MDFRCPC, Jonathan Séguin, MSc., Ann Brasey, PhD, Jean-Philippe Laverdure, PhD, Vincent T Ho, MD, Jerome Ritz, MD, Jan Storek, MD PhD, Denis-Claude Roy, MD, Lambert Busque, MD, Sébastien Lemieux, PhD, Claude Perreault, MD

Blood (2017) 130 (Supplement 1): 3249.

https://doi.org/10.1182/blood.V130.Suppl_1.3249.3249

Published: 2017

Journal Articles

Transcriptional Landscape of APL Identifies Aberrant Podoplanin Expression As a Defining Feature and Missing Link for the Bleeding Disorder of This Disease

Vincent-Philippe Lavallée, MD, Miriam Marquis, PhD, Marie-Ève Bordeleau, PhD, Jalila Chagraoui, PhD, Tara MacRae, M.Sc., Isabel Boivin, M.Sc, Geneviève Boucher, M.Sc, Patrick Gendron, M.Sc, Sébastien Lemieux, PhD, Arnaud Bonnefoy, PhD, Georges E. Rivard, MD, Josée Hébert, MD, Guy Sauvageau, MD, PhD

Blood (2016) 128 (22): 1075.

https://doi.org/10.1182/blood.V128.22.1075.1075

Published: 2016

Journal Articles

Chemo-Transcriptomic Analysis of Complex Karyotype AML Reveals Increased Expression of Cell Cycle Components and Exquisite Dependency on Polo-like Kinase 1

Vincent-Philippe Lavallée, MD, Clarisse Thiollier, PhD, Céline Moison, PhD, Marie-Ève Bordeleau, PhD, Isabel Boivin, M.Sc, Geneviève Boucher, M.Sc, Patrick Gendron, M.Sc, Sébastien Lemieux, PhD, Anne Marinier, PhD, Josée Hébert, MD, Guy Sauvageau, MD, PhD

Blood (2016) 128 (22): 769.

https://doi.org/10.1182/blood.V128.22.769.769

Published: 2016

Journal Articles

Chemo-genomic interrogation of CEBPA mutated AML reveals recurrent CSF3R mutations and subgroup sensitivity to JAK inhibitors

Vincent-Philippe Lavallée, Jana Krosl, Sébastien Lemieux, Geneviève Boucher, Patrick Gendron, Caroline Pabst, Isabel Boivin, Anne Marinier, Cynthia J. Guidos, Sylvain Meloche, Josée Hébert, Guy Sauvageau

Blood (2016) 127 (24): 3054–3061.

https://doi.org/10.1182/blood-2016-03-705053

Published: 2016

Includes: Supplemental data

Journal Articles

RNA-sequencing analysis of core binding factor AML identifies recurrent ZBTB7A mutations and defines RUNX1-CBFA2T3 fusion signature

Vincent-Philippe Lavallée, Sébastien Lemieux, Geneviève Boucher, Patrick Gendron, Isabel Boivin, Richard N. Armstrong, Guy Sauvageau, Josée Hébert

Blood (2016) 127 (20): 2498–2501.

https://doi.org/10.1182/blood-2016-03-703868

Published: 2016

Includes: Supplemental data

NARROW

Identification of Acute Myeloid Leukemia Cell Surface Therapeutic Targets Using Single Cell RNA Sequencing Supported By Surface Proteomics

Targeting PLZF Enhances Glucocorticoid Sensitivity in Acute Myeloid Leukemia

Identification of Novel Cell Surface Therapeutic Targets for KMT2A -Rearranged Acute Myeloid Leukemia

IL1R1 Expression Predicts the Benefit from Allogeneic Hematopoietic Stem Cell Transplantation in Patients with Acute Myeloid Leukemia and Intermediate-Risk Cytogenetics

UM171-Expanded Cord Blood Transplants Support Robust T-Cell Reconstitution with Low Rates of Severe Infections

High frequency of germline RUNX1 mutations in patients with RUNX1 -mutated AML

Hepatic leukemia factor is a novel leukemic stem cell regulator in DNMT3A, NPM1, and FLT3-ITD triple-mutated AML

Chemogenomic Profiling of Complex Karyotype AML Reveals a Novel Susceptibility to G2/M Checkpoint Inhibition Mediated By HMGA2 Overexpression

Mubritinib Targets the Electron Transport Chain Complex I and Reveals the Landscape of Mitochondrial Vulnerability in Acute Myeloid Leukemia

Chemogenomic Approach Unveils the Increased Susceptibility of RUNX1 -Mutated AML to Glucocorticoids

Single UM171 Expanded Cord Blood Permits Transplantation of Better HLA Matched Cords with Excellent Gvhd Relapse Free Survival

Genetic Characterization of ABT-199 Sensitivity in Human AML

Single UM171 Expanded Cord Blood Transplant Is Feasible, Safe, and Permits Transplantation of Better HLA Matched Cords with Very Low Transplant Related Mortality

HMGA2 Gene Expression Profile Improves Risk Stratification in Acute Myeloid Leukemia

Podoplanin Expression in the Bleeding Complications of Acute Promyelocytic Leukemias

Prediction of Severe Acute Graft-Versus-Host Disease (aGVHD) Based on Whole Transcriptome Sequencing of Donor CD4 T Cells

Transcriptional Landscape of APL Identifies Aberrant Podoplanin Expression As a Defining Feature and Missing Link for the Bleeding Disorder of This Disease

Chemo-Transcriptomic Analysis of Complex Karyotype AML Reveals Increased Expression of Cell Cycle Components and Exquisite Dependency on Polo-like Kinase 1

Chemo-genomic interrogation of CEBPA mutated AML reveals recurrent CSF3R mutations and subgroup sensitivity to JAK inhibitors

RNA-sequencing analysis of core binding factor AML identifies recurrent ZBTB7A mutations and defines RUNX1-CBFA2T3 fusion signature

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American Society of Hematology

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ASH Publications

American Society of Hematology

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