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Thibaut Leguay
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Journal Articles

Genetic alterations and MRD refine risk assessment for KMT2A -rearranged B-cell precursor ALL in adults: a GRAALL study

Rathana Kim, Hugo Bergugnat, Cédric Pastoret, Florence Pasquier, Emmanuel Raffoux, Lise Larcher, Marie Passet, Nathalie Grardel, Eric Delabesse, Susanne Kubetzko, Aurélie Caye-Eude, Claus Meyer, Rolf Marschalek, Marine Lafage-Pochitaloff, Anne Thiebaut-Bertrand, Marie Balsat, Martine Escoffre-Barbe, Sabine Blum, Michael Baumann, Anne Banos, Nicole Straetmans, Maria-Pilar Gallego-Hernanz, Yves Chalandon, Carlos Graux, Jean Soulier, Thibaut Leguay, Mathilde Hunault, Françoise Huguet, Véronique Lhéritier, Hervé Dombret, Nicolas Boissel, Emmanuelle Clappier
Journal: Blood
Blood (2023) 142 (21): 1806–1817.
https://doi.org/10.1182/blood.2023021501
Published: 2023
Includes: Supplemental data
Journal Articles

Tyrosine Kinase Inhibitors with Intensive Chemotherapy in AML with t(9;22)(q34.1;q11.2)/ BCR::ABL1 : Time to Reconsider Prognostic Risk? a Study from the Dataml Registry

Camille Gondran, Pierre-Yves Dumas, Audrey Bidet, Emilie Bérard, Suzanne Tavitian, Thibaut Leguay, Françoise Huguet, Isabelle Luquet, Émilie Klein, Audrey Sarry, Anne-Charlotte De Grande, Eric Delabesse, Édouard Forcade, Cécile Borel, Arnaud Pigneux, Christian Recher, Laetitia Largeaud, Sarah Bertoli
Journal: Blood
Blood (2023) 142 (Supplement 1): 1473.
https://doi.org/10.1182/blood-2023-180817
Published: 2023
Journal Articles

Levofloxacin to Prevent Bacterial Infection in Patients with Acute Myeloid Leukemia Treated By Azacitidine and Venetoclax: A Study from the Dataml Registry

Xavier Brousse, Nicolas Rasandisona, Harmony Leroy, Karen Delavigne, Nathan Mottal, Suzanne Tavitian, Thibaut Leguay, Leopoldine Lapierre, Eric Delabesse, Audrey Bidet, Martin Gauthier, Diane Lara, Claire Calmettes, Audrey Sarry, Noemie Gadaud, Benoit Branco, anne-Charlotte de Grande, Clementine Beranger, Christian Recher, Arnaud Pigneux, Sarah Bertoli, Pierre-Yves Dumas
Journal: Blood
Blood (2023) 142 (Supplement 1): 7443.
https://doi.org/10.1182/blood-2023-182117
Published: 2023
Journal Articles

Oncogenetic-Driven Targeted Therapy for Relapsed/Refractory T-Cell Acute Lymphoblastic Leukemia : A French ALL-Target Observatory Report

Aurelie Cabannes-Hamy, Lucien Courtois, Marie Balsat, Mathieu Simonin, Françoise Huguet, Martine Escoffre-Barbe, Florence Pasquier, Caroline Bonmati, Pascal Turlure, Thomas Cluzeau, Delphine Lebon, Eve Gehlkopf, Eolia Brissot, Justine Decroocq, Patrice Chevallier, Sylvain Chantepie, Victoria Cacheux, Sebastien Maury, Safia Chebrek, Thibaut Leguay, Melody Fort, Natacha Mauz, Mathlide Lamarque, Hunault-Berger Mathilde, Stefan Wickenhauser, Jamilé Frayfer, Anne Banos, Emmanuelle Tavernier, Denis Caillot, Anne Marie Ronchetti, Celine Berthon, Etienne Lengline, Véronique Lhéritier, Hervé Dombret, Ambroise Marçais, Antoine Pinton, Guillaume P Andrieu, Nicolas Boissel, Ludovic Lhermitte, Vahid Asnafi, Philippe Rousselot
Journal: Blood
Blood (2023) 142 (Supplement 1): 518.
https://doi.org/10.1182/blood-2023-179192
Published: 2023
Journal Articles

Combination Chemotherapy in Patients with Newly Diagnosed Blastic Plasmacytoid Dendritic Cell Neoplasms (BPDCN): First Results of a Prospective French Trial (LpDessai)

Eric Deconinck, Berengere Gruson, Sabeha Biichle, Anne Roggy, Florian Renosi, Thomas Fournet, Maxime Desmarets, Gregory Tio, Tony Marchand, Mikael Roussel, Thibaut Leguay, Jean-Philippe Vial, Francoise Huguet, Francois Vergez, Emilie Chalayer, Khaoula Mahfoudi, Fressia Honeyman, Sebastien Maury, Nicolas Freynet, Caroline Bonmati, Veronique Latger-Cannard, Eve Gehlkopf, Caroline Bret, Damien Roos Weil, Magali Le Garff-Tavernier, Sophie Rigaudeau, Gandhi Laurent Damaj, Edouard Cornet, Remy Gressin, Marie-Christine Jacob, Delphine Martineau, Aguirre Mimoun, Alice Garnier, Marion Eveillard, Alban Villate, Emmanuelle Rault, Fanny Delettre, Francine Garnache Ottou
Journal: Blood
Blood (2023) 142 (Supplement 1): 1516.
https://doi.org/10.1182/blood-2023-173379
Published: 2023
Journal Articles

Efficacy and Tolerance of Brexucabtagene Autoleucel in Adults with Relapsed/Refractory B-Cell Precursor Acute Lymphoblastic Leukemia : A Graall Study from the Descar-T Registry

Florence Rabian, David Beauvais, Tony Marchand, Sabine Furst, Anne Huynh, Eolia Brissot, Sebastien Maury, Ludovic Gabellier, Patrice Chevallier, Michael Loschi, Stéphanie Nguyen Quoc, Marie Balsat, Ingrid Lafon, Amandine Fayard, Vincent Camus, Célestine Simand, Niels Moya, Cristina Castilla-Llorente, Magalie Joris, Ana Berceanu, Anne Thiebaut, Véronique Lhéritier, Eve Gehlkopf, Gabrielle Roth-Guepin, Thibaut Leguay, Nicolas Boissel
Journal: Blood
Blood (2023) 142 (Supplement 1): 3498.
https://doi.org/10.1182/blood-2023-180575
Published: 2023
Journal Articles

Venetoclax and Azacitidine for Molecular Relapse during First Line Intensive Chemotherapy in Patients with NPM1 Mutated or Core Binding Factor (CBF) AML. a Study from the Dataml Registry

Jules Higué, Pierre-Yves Dumas, Laetitia Largeaud, Audrey Bidet, Émilie Klein, Olivier Mansier, Lucie Rigolot, Eric Delabesse, Anne Banos, Suzanne Tavitian, Thibaut Leguay, Sarah Guenounou, Edouard Forcade, Sarah Bertoli, Arnaud Pigneux, Christian Recher
Journal: Blood
Blood (2023) 142 (Supplement 1): 2887.
https://doi.org/10.1182/blood-2023-180773
Published: 2023
Journal Articles

Exploring the Heterogeneity of Response to Blinatumomab in High-Risk Philadelphia-Negative B-Cell Precursor Acute Lymphoblastic Leukemia: An Analysis from the QUEST Sub-Study of the Graall-2014/B Trial

Nicolas Boissel, Francoise Huguet, Thibaut Leguay, Mathilde Hunault, Rathana KIM, Yosr Hicheri, Marie Passet, Patrice Chevallier, Marie Balsat, Sebastien Maury, Anne Thiebaut, Florence Van Obbergh, Thomas Cluzeau, Martine Escoffre Barbe, Nicole Straetmans, Johanna Konopacki, Amine Belhabri, Alban Villate, Florence Pasquier, Didier Bouscary, Thorsten Braun, Sabine Blum, Victoria Cacheux, Caroline Bonmati, Sebastian Wittnebel, Véronique Lhéritier, Norbert Ifrah, Carlos Graux, Yves Chalandon, Emmanuelle Clappier, Herve Dombret
Journal: Blood
Blood (2023) 142 (Supplement 1): 4349.
https://doi.org/10.1182/blood-2023-177847
Published: 2023
Journal Articles

Frontline Consolidation with Nelarabine for Adults with High-Risk T-Cell Acute Lymphoblastic Leukemia. Results of the Graall-2014/T Atriall Phase 2 Study

Nicolas Boissel, Carlos Graux, Francoise Huguet, Florence Pasquier, Aurore Touzart, Thomas Cluzeau, Ludovic Lhermitte, Eric Delabesse, Patrice Chevallier, Mathilde Hunault, Cedric Pastoret, Sebastien Maury, Nathalie Grardel, Martine Escoffre Barbe, Pascal Turlure, Beat Schafer, Marie Balsat, Philippe Rousselot, Thibaut Leguay, Eric Jourdan, Delphine Pranger, Michael Gregor, Emilie Lemasle, Anne Marie Ronchetti, Ana Berceanu, Ingrid Lafon, Madalina Uzunov, Etienne Lengline, Norbert Ifrah, Yves Chalandon, Véronique Lhéritier, Vahid Asnafi, Herve Dombret
Journal: Blood
Blood (2023) 142 (Supplement 1): 962.
https://doi.org/10.1182/blood-2023-177696
Published: 2023
Journal Articles

Updated Outcomes from the Historical Control Study SCHOLAR-3 Contextualizing ZUMA-3 Results of Brexucabtagene Autoleucel (KTE-X19) in Adult Patients with Relapsed or Refractory B-Cell Acute Lymphoblastic Leukemia (R/R B-ALL)

Bijal D. Shah, Armin Ghobadi, Olalekan O. Oluwole, Aaron C. Logan, Nicolas Boissel, Ryan D. Cassaday, Thibaut Leguay, Michael R. Bishop, Max S. Topp, Dimitrios Tzachanis, Kristen M. O'Dwyer, Martha L. Arellano, Yi Lin, Maria R. Baer, Gary J. Schiller, Jae H Park, Marion Subklewe, Mehrdad Abedi, Monique C. Minnema, William G. Wierda, Daniel J. DeAngelo, Patrick Stiff, Deepa Jeyakumar, Jinghui Dong, Sabina Adhikary, Lang Zhou, Petra C. Schuberth, Imi Faghmous, Behzad Kharabi Masouleh, Roch Houot
Journal: Blood
Blood (2022) 140 (Supplement 1): 3158–3161.
https://doi.org/10.1182/blood-2022-158248
Published: 2022
Journal Articles

Epag 2015 : A Phase II Randomized Placebo-Controlled Study to Assess the Impact on Outcome of Eltrombopag Administered to Elderly Patients with Acute Myeloid Leukemia Receiving Induction Chemotherapy. a French Innovative Leukemia Organization (FILO) Study

Arnaud Pigneux, Pierre-Yves Dumas, Marc Bernard, Norbert Vey, Audrey Bidet, Ariane Mineur, Mathilde Hunault, Martin Carre, Mario Ojeda, Anne Banos, Pierre Peterlin, Romain Guieze, Yohan Desbrosses, Gabrielle Roth Guepin, Celestine Simand, Thibaut Leguay, Emmanuel Gyan, Eric Jourdan, Jean-Philippe Vial, Tony Marchand, Yosr Hicheri, Marie C Bene, Jean Francois Hamel, Christian Recher
Journal: Blood
Blood (2022) 140 (Supplement 1): 6142–6144.
https://doi.org/10.1182/blood-2022-167000
Published: 2022
Journal Articles

Blinatumomab during Consolidation in High-Risk Philadelphia Chromosome (Ph)-Negative B-Cell Precursor (BCP) Acute Lymphoblastic Leukemia (ALL) Adult Patients: A Two-Cohort Comparison within the Graall-2014/B Study

Nicolas Boissel, Francoise Huguet, Thibaut Leguay, Mathilde Hunault, Rathana KIM, Yosr Hicheri, Patrice Chevallier, Marie Balsat, Sébastien Maury, Anne Thiebaut-Bertrand, Florence Van Obbergh, Thomas Cluzeau, Martine Escoffre-Barbe, Nicole Straetmans, Johanna Konopacki, Amine Belhabri, Alban Villate, Florence Pasquier, Ioana Vaida, Laurence Sanhes, Magda Alexis, Cedric Pastoret, Mathlide Lamarque, Laure Farnault, Nathalie Grardel, Celine Berthon, Eric Delabesse, Veronique Lheritier, Norbert Ifrah, Carlos Graux, Yves Chalandon, Emmanuelle Clappier, Herve Dombret
Journal: Blood
Blood (2022) 140 (Supplement 1): 507–509.
https://doi.org/10.1182/blood-2022-159397
Published: 2022
Journal Articles

In Adults with Ph-Negative Acute Lymphoblastic Leukemia (ALL), Age-Adapted Chemotherapy Intensity and MRD-Driven Transplant Indication Significantly Reduces Treatment-Related Mortality (TRM) and Improves Overall Survival - Results from the Graall-2014 Trial

Nicolas Boissel, Francoise Huguet, Thibaut Leguay, Hunault-Berger Mathilde, Carlos Graux, Yves Chalandon, Eric Delabesse, Yosr Hicheri, Patrice Chevallier, Marie Balsat, Cedric Pastoret, Martine Escoffre-Barbe, Florence Pasquier, Jean-Pierre Marolleau, Anne Thiebaut-Bertrand, Anne Huynh, Nathalie Dhedin, Emilie Lemasle, Caroline Bonmati, Sébastien Maury, Gaëlle Guillerm, Anna Berceanu, Urs Schanz, Thomas Cluzeau, Pascal Turlure, Philippe Rousselot, Bernard J.M. De Prijck, Nathalie Grardel, Marie C Bene, Marine Lafage, Norbert Ifrah, Veronique Lheritier, Vahid Asnafi, Emmanuelle Clappier, Herve Dombret
Journal: Blood
Blood (2022) 140 (Supplement 1): 112–114.
https://doi.org/10.1182/blood-2022-157903
Published: 2022
Journal Articles

Concurrent CDX2 cis -deregulation and UBTF::ATXN7L3 fusion define a novel high-risk subtype of B-cell ALL

Marie Passet, Rathana Kim, Stéphanie Gachet, François Sigaux, Julie Chaumeil, Ava Galland, Thomas Sexton, Samuel Quentin, Lucie Hernandez, Lise Larcher, Hugo Bergugnat, Tao Ye, Nezih Karasu, Aurélie Caye, Beate Heizmann, Isabelle Duluc, Patrice Chevallier, Philippe Rousselot, Françoise Huguet, Thibaut Leguay, Mathilde Hunault, Françoise Pflumio, Jean-Noël Freund, Camille Lobry, Véronique Lhéritier, Hervé Dombret, Claire Domon-Dell, Jean Soulier, Nicolas Boissel, Emmanuelle Clappier
Journal: Blood
Blood (2022) 139 (24): 3505–3518.
https://doi.org/10.1182/blood.2021014723
Published: 2022
Includes: Supplemental data
Journal Articles

Impact of Central Nervous System Involvement in Adult Patients with Acute Lymphoblastic Leukemia Treated in a Pediatrics-Inspired Protocol - a Graall Study

Corentin Orvain, Sylvain Chantepie, Xavier Thomas, Martine Escoffre-Barbe, Francoise Huguet, Yohan Desbrosses, Gaelle Guillerm, Thibaut Leguay, Sarah Barbieux, Norbert Vey, Patrice Chevallier, Jean Valere Malfuson, Stephane Lepretre, Jean Pierre Marolleau, Hacene Zerazhi, Diana Carp, Ambroise Marçais, Maria Pilar Gallego Hernanz, Iona Vaida, Florence Pasquier, Veronique Lheritier, Norbert Ifrah, Hervé Dombret, Nicolas Boissel, Hunault-Berger Mathilde
Journal: Blood
Blood (2021) 138 (Supplement 1): 215.
https://doi.org/10.1182/blood-2021-150705
Published: 2021
Journal Articles

Frontline Consolidation with Blinatumomab for High-Risk Philadelphia-Negative Acute Lymphoblastic Adult Patients. Early Results from the Graall-2014-QUEST Phase 2

Nicolas Boissel, Francoise Huguet, Carlos Graux, Yosr Hicheri, Patrice Chevallier, Rathana KIM, Marie Balsat, Thibaut Leguay, Mathilde Hunault, Sébastien Maury, Anne Thiebaut-Bertrand, Martine Escoffre-Barbe, Thomas Cluzeau, Alban Villate, Florence Pasquier, Laure Farnault, Florence Van Obbergh, Philippe Rousselot, Yves Chalandon, Eric Delabesse, Cedric Pastoret, Emmanuelle Clappier, Veronique Lheritier, Herve Dombret
Journal: Blood
Blood (2021) 138 (Supplement 1): 1232.
https://doi.org/10.1182/blood-2021-146163
Published: 2021
Journal Articles

Unsupervised Flow Cytometry Analysis: Application to Minimal Residual Disease Detection in a Cohort of 40 Acute Myeloblastic Leukemia Patients with Molecular Markers

Nicolas Lechevalier, PharmD, Jean-Philippe Vial, MD, Francis Lacombe, MDPhD, Pierre-Yves Dumas, MDPhD, Audrey Bidet, PharmD, Thibaut Leguay, MD, Francois Vergez, DVM, PhD, Arnaud Pigneux, MD PhD, Marie C Béné, PharmSciD, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 30.
https://doi.org/10.1182/blood-2020-141199
Published: 2020
Journal Articles

Acute Myeloid Leukemia and Antifungal Prophylaxis Era: Compliance of AML Centers, Invasive Fungal Infection (IFI) Classification, IFI Incidence and AML Outcomes from ALFA 2007- 02 Study

Mauricette Michallet, MD PhD, Mohamad Sobh, PharmD, Stephane Morisset, BioStat, Alexandre Deloire, CRA, Emmanuel Raffoux, MD, Stephane De Botton, Denis Caillot, MD, Sylvain Chantepie, MD, Stephane Girault, MD, Celine Berthon, MD, Sarah Bertoli, MD PhD, Stephane Lepretre, Thibaut Leguay, MD, Sylvie Castaigne, MD, Jean-Pierre Marolleau, MD PhD, Cecile Pautas, MD, Jean Valère Malfuson, MD, Norbert Vey, MD PhD, Lauris Gastaud, Felipe Suarez, MD PhD, Aline Schmidt, MD, Rémy Gressin, MD, Caroline Bonmati, MD, Karine Celli-Lebras, CRA, Mohamed El-Hamri, CRA, Patricia Ribaud, MD, Herve Dombret, MD PhD, Xavier Thomas, MD PhD, Anne Bergeron
Journal: Blood
Blood (2019) 134 (Supplement_1): 2618.
https://doi.org/10.1182/blood-2019-130642
Published: 2019
Journal Articles

PAX5 P80R mutation identifies a novel subtype of B-cell precursor acute lymphoblastic leukemia with favorable outcome

Marie Passet, Nicolas Boissel, François Sigaux, Colombe Saillard, Mario Bargetzi, Ibrahima Ba, Xavier Thomas, Carlos Graux, Yves Chalandon, Thibaut Leguay, Etienne Lengliné, Johanna Konopacki, Samuel Quentin, Eric Delabesse, Marina Lafage-Pochitaloff, Cédric Pastoret, Nathalie Grardel, Vahid Asnafi, Véronique Lhéritier, Jean Soulier, Hervé Dombret, Emmanuelle Clappier
Journal: Blood
Blood (2019) 133 (3): 280–284.
https://doi.org/10.1182/blood-2018-10-882142
Published: 2019
Includes: Supplemental data
Journal Articles

Acute Myeloblastic Leukemia Relapse after Allogeneic Stem Cell Transplantation

Mediavilla Clémence, Stéphane Vigouroux, Reza Tabrizi, MD, Laurence Clement, Anne Banos, MD, Pascal Turlure, MD, Xavier Lafarge, Pierre-Yves Dumas, MD, Thibaut Leguay, MD, Arnaud Pigneux, MD PhD, Noel Milpied, MD, Edouard Forcade, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 5737.
https://doi.org/10.1182/blood-2018-99-119021
Published: 2018