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Regina M. Myers
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Journal Articles

Quadriparesis and paraparesis following chimeric antigen receptor T-cell therapy in children and adolescents

Clinical Trials & Observations
Caroline Diorio, Laura Hernandez-Miyares, Diego A. Espinoza, Brenda L. Banwell, Amit Bar-Or, Amanda M. DiNofia, Allison Barz Leahy, Zachary Martinez, Regina M. Myers, Sarah E. Hopkins, Susan R. Rheingold, David T. Teachey, Angela N. Viaene, Lisa M. Wray, Shannon L. Maude, Stephan A. Grupp, Jennifer L. McGuire
Journal: Blood
Blood (2024) 144 (13): 1387–1398.
https://doi.org/10.1182/blood.2024023933
Published: 2024
Includes: Supplemental data
Journal Articles

Comparative Effectiveness of Reinduction Approaches for Pediatric Relapsed Acute Myeloid Leukemia

Caitlin W. Elgarten, Regina M. Myers, Alix E. Seif, Yimei Li, Daniel J. Zheng, Naomi J Winick, Elaine Morgan, Rajen Mody, Arunkumar Modi, Tamara P. Miller, Kelly Maloney, Mallorie M. Heneghan, M. Monica Gramatges, Brian T. Fisher, Kelly D. Getz, Richard Aplenc
Journal: Blood
Blood (2023) 142 (Supplement 1): 551.
https://doi.org/10.1182/blood-2023-188044
Published: 2023
Journal Articles

Survival Disparities By Frontline Clinical Trial Enrollment Status for Treatment of Pediatric Acute Myeloid Leukemia

Daniel J. Zheng, Elsa van der Mei, Yimei Li, Yuan-Shung V. Huang, Catherine Aftandilian, Kira Bona, Emi Caywood, Anderson B. Collier, M. Monica Gramatges, Mallorie M. Heneghan, Meret Henry, Craig Lotterman, Kelly Maloney, Tamara P. Miller, Arunkumar Modi, Rajen Mody, Elaine Morgan, Naomi J. Winick, Jennifer J. Wilkes, Victor Wong, Haley Newman, Regina M. Myers, Caitlin W. Elgarten, Alix E. Seif, Brian T. Fisher, Richard Aplenc, Kelly D. Getz
Journal: Blood
Blood (2023) 142 (Supplement 1): 2430.
https://doi.org/10.1182/blood-2023-189240
Published: 2023
Journal Articles

Racial and Ethnic Differences in Acuity and Cumulative Frontline Organ Toxicity at the Time of Relapse in Pediatric Acute Myeloid Leukemia

Daniel J. Zheng, Yimei Li, Yuan-Shung V. Huang, Catherine Aftandilian, Kira Bona, Emi Caywood, Anderson B. Collier, M. Monica Gramatges, Mallorie M. Heneghan, Meret Henry, Craig Lotterman, Kelly Maloney, Tamara P. Miller, Arunkumar Modi, Rajen Mody, Elaine Morgan, Naomi J. Winick, Jennifer J. Wilkes, Victor Wong, Cody Gathers, Haley Newman, Reneé H. Moore, Regina M. Myers, Caitlin W. Elgarten, Alix E. Seif, Brian T. Fisher, Richard Aplenc, Kelly D. Getz
Journal: Blood
Blood (2023) 142 (Supplement 1): 387.
https://doi.org/10.1182/blood-2023-180713
Published: 2023
Journal Articles

IL-10 Levels Differentially Regulate IFNg Signaling of CART19 and CART22

Caroline Diorio, Regina M. Myers, Anastasia Frank-Kamenetski, Rawan Shraim, Amanda M. Dinofia, Zachary Martinez, Ohaila Mustafa, Joseph A Fraietta, Vanessa Gonzalez, Vivian Yi, Lahari Uppuluri, Haley Newman, Edward Behrens, Carl June, Scott Canna, Stephan Grupp, David T. Teachey
Journal: Blood
Blood (2023) 142 (Supplement 1): 3431.
https://doi.org/10.1182/blood-2023-182377
Published: 2023
Journal Articles

Establishing Real-World Data-Driven Response Criteria in Pediatric Acute Myeloid Leukemia

Richard Aplenc, Yimei Li, Julianne Ani, Caitlin W. Elgarten, Lisa D'Errico, Todd Cooper, E. Anders Kolb, Maria Monica Gramatges, Meret Henry, Tamara P. Miller, Rajen Mody, Elaine Morgan, Regina M. Myers, Jessica A. Pollard, Alix Seif, Brian T. Fisher, Kelly D. Getz
Journal: Blood
Blood (2023) 142 (Supplement 1): 726.
https://doi.org/10.1182/blood-2023-185647
Published: 2023
Journal Articles

Outcomes and Toxicities after Allogeneic Hematopoietic Cell Transplant for Remission Consolidation or Relapse Therapy after CD19 Chimeric Antigen Receptor T Cell Therapy in Children and Young Adults with Acute Lymphoblastic Leukemia

Regina M. Myers, Sarah Mumanachit, Shannon L. Maude, Amanda M. Dinofia, Jason L. Freedman, Nancy Bunin, Lisa Wray, Allison Barz Leahy, Timothy S Olson, Stephan Grupp, Alix E. Seif, Caitlin W. Elgarten
Journal: Blood
Blood (2023) 142 (Supplement 1): 3767.
https://doi.org/10.1182/blood-2023-188047
Published: 2023
Journal Articles

How I use risk factors for success or failure of CD19 CAR T cells to guide management of children and AYA with B-cell ALL

Regina M. Myers, Nirali N. Shah, Michael A. Pulsipher
Journal: Blood
Blood (2023) 141 (11): 1251–1264.
https://doi.org/10.1182/blood.2022016937
Published: 2023
Journal Articles

Impact of poverty and neighborhood opportunity on outcomes for children treated with CD19-directed CAR T-cell therapy

Clinical Trials & Observations
Haley Newman, Yimei Li, Hongyan Liu, Regina M. Myers, Vicky Tam, Amanda DiNofia, Lisa Wray, Susan R. Rheingold, Colleen Callahan, Claire White, Diane Baniewicz, Lena E. Winestone, Stephan Kadauke, Caroline Diorio, Carl H. June, Kelly D. Getz, Richard Aplenc, David T. Teachey, Shannon L. Maude, Stephan A. Grupp, Kira Bona, Allison Barz Leahy
Journal: Blood
Blood (2023) 141 (6): 609–619.
https://doi.org/10.1182/blood.2022017866
Published: 2023
Includes: Supplemental data
Journal Articles

Influence of Household Income on Health-Related Quality of Life in Children with Acute Myeloid Leukemia

Haley Newman, Yimei Li, Yuan-Shung V. Huang, Caitlin W Elgarten, Regina M. Myers, Jenny Ruiz, Allison Barz Leahy, Catherine Aftandilian, Staci D. Arnold, Kira O Bona, Mallorie M. Heneghan, M Monica Gramatges, Kelly W Maloney, Arunkumar J. Modi, Rajen Mody, Naomi J Winick, Elaine Morgan, Jennifer J. Wilkes, Alix E. Seif, Brian T. Fisher, Richard Aplenc, Kelly D. Getz
Journal: Blood
Blood (2022) 140 (Supplement 1): 11001–11003.
https://doi.org/10.1182/blood-2022-160336
Published: 2022
Journal Articles

CD22-Targeted CAR-Modified T-Cells Safely Induce Remissions in Children and Young Adults with Relapsed, CD19-Negative B-ALL after Treatment with CD19-Targeted CAR T-Cells

Regina M. Myers, Amanda M. DiNofia, Yimei Li, Caroline Diorio, Richard Aplenc, Diane Baniewicz, Jennifer L Brogdon, Colleen Callahan, Boris Engels, Joseph A. Fraietta, Vanessa Gonzalez, Emma Iannone, Allison Barz Leahy, Hongyan Liu, Susan E. McClory, Susan R. Rheingold, Laura Shinehouse, Gerald Wertheim, Lisa Wray, Noelle V. Frey, Shannon L. Maude, Stephan A. Grupp
Journal: Blood
Blood (2022) 140 (Supplement 1): 2376–2377.
https://doi.org/10.1182/blood-2022-168139
Published: 2022
Journal Articles

Comprehensive Secretome Profiling Elucidates Novel Disease Biology and Identifies Pre-Infusion Candidate Biomarkers to Predict the Development of Severe Cytokine Release Syndrome in Pediatric Patients Receiving CART19

Caroline Diorio, Rawan Shraim, Regina M. Myers, Chakkapong Burudpakdee, Allison Barz Leahy, Richard Aplenc, Michele P. Lambert, Hamid Bassiri, Edward M Behrens, Vanessa E. Gonzalez, Fang Chen, Bruce L Levine, Shannon L. Maude, Amanda M. DiNofia, Alix E. Seif, J. Joseph Melenhorst, Simon F Lacey, Carl H June, David Barrett, Stephan A. Grupp, David T. Teachey
Journal: Blood
Blood (2021) 138 (Supplement 1): 167.
https://doi.org/10.1182/blood-2021-149477
Published: 2021
Journal Articles

Complete Versus Incomplete Hematologic Recovery after CAR T Cell Therapy: Implications for Relapse Free Survival and Overall Survival in Pediatric and Young Adult Patients with Relapsed/Refractory B-ALL

Benjamin J Lerman, Yimei Li, Hongyan Liu, Regina M. Myers, Kaitlin Devine, Colleen Callahan, Diane Baniewicz, Stephan Kadauke, Amanda M. DiNofia, Susan R. Rheingold, Lisa Wray, Richard Aplenc, Stephan A. Grupp, Shannon L. Maude, Allison Barz Leahy
Journal: Blood
Blood (2021) 138 (Supplement 1): 1747.
https://doi.org/10.1182/blood-2021-151114
Published: 2021
Journal Articles

Outcomes after Reinfusion of CD19-Specific Chimeric Antigen Receptor (CAR)-Modified T Cells in Children and Young Adults with Relapsed/Refractory B-Cell Acute Lymphoblastic Leukemia

Regina M. Myers, Kaitlin Devine, Yimei Li, Sophie Lawrence, Allison Barz Leahy, Hongyan Liu, Lauren Vernau, Colleen Callahan, Diane Baniewicz, Stephan Kadauke, Regina McGuire, Margaret A Cameron, Amanda M. DiNofia, Susan R. Rheingold, Richard Aplenc, Carl H June, Stephan A. Grupp, Lisa Wray, Shannon L. Maude
Journal: Blood
Blood (2021) 138 (Supplement 1): 474.
https://doi.org/10.1182/blood-2021-147299
Published: 2021
Journal Articles

Ikaros Mediates Antigen Escape Following CD19 CAR T Cell Therapy in r/r B-ALL

Pablo Domizi, Jolanda Sarno, Astraea Jager, Reema Baskar, Warren D. Reynolds, Bita Sahaf, Sean Bendall, Charles G. Mullighan, Allison Barz Leahy, Regina M. Myers, Stephan A. Grupp, Elena Sotillo, David Barrett, Kara L. Davis
Journal: Blood
Blood (2021) 138 (Supplement 1): 613.
https://doi.org/10.1182/blood-2021-151002
Published: 2021
Journal Articles

KMT2A Rearrangements Are Associated with Lineage Switch Following CD19 Targeting CAR T-Cell Therapy

Adam J. Lamble, Regina M. Myers, Agne Taraseviciute, Samuel John, Bonnie Yates, Seth M. Steinberg, Jennifer Sheppard, Alexandra E. Kovach, Brent L. Wood, Michael Borowitz, Maryalice Stetler-Stevenson, Constance M. Yuan, Vinodh Pillai, Toni Foley, Perry Chung, Lee Chen, Daniel W. Lee, Colleen Annesley, Amanda M. DiNofia, Stephan A. Grupp, Michael R Verneris, Lia Gore, Theodore W. Laetsch, Deepa Bhojwani, Patrick A. Brown, Michael A. Pulsipher, Susan R. Rheingold, Rebecca A Gardner, Nirali N. Shah
Journal: Blood
Blood (2021) 138 (Supplement 1): 256.
https://doi.org/10.1182/blood-2021-153336
Published: 2021
Journal Articles

Pre-CAR Blinatumomab Is Associated with Increased Post-CD19 CAR Relapse and Decreased Event Free Survival

Agne Taraseviciute, MD, Seth M. Steinberg, PhD, Regina M. Myers, MD, Lia Gore, MD, Adam J. Lamble, MD, Patrick A. Brown, MD, Jennifer Sheppard, Bonnie Yates, NP, Perry Chung, MD, Lee Chen, Colleen Annesley, MD, Deepa Bhojwani, MD, Theodore W. Laetsch, MD, Rebecca A Gardner, MD, Susan R. Rheingold, MD, Michael A Pulsipher, MD, Nirali N. Shah, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 13–14.
https://doi.org/10.1182/blood-2020-139260
Published: 2020
Journal Articles

Trends in Inpatient and Intensive Care Resource Utilization after Chimeric Antigen Receptor T Cell Therapy for Pediatric Acute Lymphoblastic Leukemia from 2012-2019

Regina M. Myers, MD, Julie C Fitzgerald, MD, Amanda M. DiNofia, MD, Lisa Wray, MD, Allison Barz Leahy, MD, Yimei Li, PhD, Laura Smith, RN, MSN, CRNP, Evanette Burrows, MPH, Mark Ramos, BS, Laura S Motley, BSc, BSN, RN, Raabia N Khan, MPH, Kelly D Getz, Richard Aplenc, MD PhD, Stephan Grupp, MD PhD, Shannon L. Maude, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 61.
https://doi.org/10.1182/blood-2019-126724
Published: 2019
Journal Articles

Cytogenetic Characteristics and Outcomes of Patients Receiving CTL019 CAR T Cell Therapy

Allison Barz Leahy, MD, Kaitlin J. Stanley, MD, Regina M. Myers, MD, Amanda M. DiNofia, MD, Lisa Wray, MD, Susan R. Rheingold, MD, Colleen Callahan, CRNP, Diane Baniewicz, CRNP, Amy E. Barry, PPCNP-BC, Maria M. Patino, BS, Stephen P. Hunger, MD, Stephan Grupp, MD PhD, David M. Barrett, Shannon L. Maude, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1464.
https://doi.org/10.1182/blood-2019-130060
Published: 2019
Journal Articles

Comparative Effectiveness of Rasburicase and Allopurinol in Children with Acute Lymphoblastic Leukemia: An Emulated Pragmatic Trial Using Observational Data

Regina M Myers, MD, Kelly D Getz, PhD, Yimei Li, PhD, Yuan-Shung V. Huang, MS, Rebecca Citrin, MD, Caitlin W Elgarten, MD, Benjamin L Laskin, MD, Joseph P. Horowitz, Brian T. Fisher, DO, Richard Aplenc, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 830.
https://doi.org/10.1182/blood-2018-99-114883
Published: 2018