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Rawan Shraim
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Journal Articles

IL-10 Levels Differentially Regulate IFNg Signaling of CART19 and CART22

Caroline Diorio, Regina M. Myers, Anastasia Frank-Kamenetski, Rawan Shraim, Amanda M. Dinofia, Zachary Martinez, Ohaila Mustafa, Joseph A Fraietta, Vanessa Gonzalez, Vivian Yi, Lahari Uppuluri, Haley Newman, Edward Behrens, Carl June, Scott Canna, Stephan Grupp, David T. Teachey
Journal: Blood
Blood (2023) 142 (Supplement 1): 3431.
https://doi.org/10.1182/blood-2023-182377
Published: 2023
Journal Articles

Comprehensive Genome Characterization of Childhood T-ALL Links Oncogene Activation Mechanism and Subtypes to Prognosis

Petri Pölönen, Abdelrahman Elsayed, Danika Di Giacomo, Lindsey Montefiori, Shunsuke Kimura, Jason Myers, Dale Hedges, Jason Xu, Yawei Hui, Zhongshan Cheng, Yiping Fan, Ilaria Iacobucci, Yunchao Chang, Rawan Shraim, Meenakshi Devidas, Stuart S. Winter, Kimberly P. Dunsmore, Jun J.J. Yang, Tiffaney L. Vincent, Kai Tan, Changya Chen, Haley Newman, Mignon L. Loh, Elizabeth A. Raetz, Stephen P. Hunger, Evadnie Rampersaud, Ti-Cheng Chang, Gang Wu, Stanley B. Pounds, Charles G. Mullighan, David T. Teachey
Journal: Blood
Blood (2022) 140 (Supplement 1): 1727–1729.
https://doi.org/10.1182/blood-2022-167157
Published: 2022
Journal Articles

Progenitor Sub-Populations in Treatment Resistant T-ALL

Jason Xu, Changya Chen, Tiffaney L. Vincent, Petri Pölönen, Abdelrahman Elsayed, Jianzhong Hu, Satoshi Yoshimura, Wenbao Yu, Chia-hui Chen, Elizabeth Li, Rawan Shraim, Marieke Lavaert, Haley Newman, Yang-yang Ding, Anusha Thadi, Kyung Jin Ahn, Jacqueline Peng, Chujie Gong, Yusha Sun, Shovik Bandyopadhyay, David Frank, Mignon L. Loh, Elizabeth A. Raetz, Zhiguo Chen, Brent L. Wood, Meenakshi Devidas, Kimberly P. Dunsmore, Stuart S. Winter, Gang Wu, Avinash Bhandoola, Stanley B. Pounds, Stephen P. Hunger, Jun J. Yang, Charles G. Mullighan, David T. Teachey, Kai Tan
Journal: Blood
Blood (2022) 140 (Supplement 1): 1724–1726.
https://doi.org/10.1182/blood-2022-166521
Published: 2022
Journal Articles

Single-Cell Pan-Cancer Analysis Reveals Treatment Resistance Stem/Progenitor-like Subpopulation in the High-Risk Pediatric Leukemia

Changya Chen, Jason Xu, Tiffaney L. Vincent, Wenbao Yu, Yang Y Ding, Chia-hui Chen, Samuel Kim, Elizabeth Li, Shovik Bandyopadhyay, Petri Pölönen, Abdelrahman Elsayed, Haley Newman, Brent L. Wood, Jianzhong Hu, Rawan Shraim, Mignon L. Loh, Elizabeth A. Raetz, Stephen P. Hunger, Stanley B. Pounds, Jun J. Yang, Charles G. Mullighan, David Frank, Kathrin M. Bernt, David T. Teachey, Kai Tan
Journal: Blood
Blood (2022) 140 (Supplement 1): 1273–1274.
https://doi.org/10.1182/blood-2022-167057
Published: 2022
Journal Articles

The Influence of Genetic Ancestry on Disease Biology in Pediatric T-Cell Acute Lymphoblastic Leukemia

Haley Newman, Shawn Lee, Petri Pölönen, Rawan Shraim, Yimei Li, Hongyan Liu, Tiffaney L. Vincent, Richard Aplenc, Changya Chen, Zhiguo Chen, Caroline Diorio, Kimberly P. Dunsmore, Sumit Gupta, Gang Wu, Kai Tan, Meenakshi Devidas, Stuart S. Winter, Brent L. Wood, Lena E. Winestone, Jason Xu, Elizabeth A. Raetz, Mignon L. Loh, Stephen P. Hunger, Stanley B. Pounds, Kira O Bona, Charles G. Mullighan, Jun J. Yang, David T. Teachey
Journal: Blood
Blood (2022) 140 (Supplement 1): 3458–3460.
https://doi.org/10.1182/blood-2022-159159
Published: 2022
Journal Articles

Targeting CD38 in T-ALL Upregulates the Targetable Polyamine Metabolism Pathway

Caroline Diorio, Tiffaney L. Vincent, Tori Fuller, Rawan Shraim, Tina Glisovic-Aplenc, Theresa Ryan, Kimberly Veliz, Haley Newman, Gerald Wertheim, Hamid Bassiri, Annette Vu, Michael Hogarty, Carl H June, Stephan A. Grupp, Sarah K Tasian, Richard Aplenc, Saar Gill, David T. Teachey
Journal: Blood
Blood (2022) 140 (Supplement 1): 10285–10286.
https://doi.org/10.1182/blood-2022-167893
Published: 2022
Journal Articles

Cytosine base editing enables quadruple-edited allogeneic CART cells for T-ALL

Caroline Diorio, Ryan Murray, Mark Naniong, Luis Barrera, Adam Camblin, John Chukinas, Lindsey Coholan, Aaron Edwards, Tori Fuller, Claudia Gonzales, Stephan A. Grupp, Alden Ladd, Melissa Le, Angelica Messana, Faith Musenge, Haley Newman, Yeh-Chuin Poh, Henry Poulin, Theresa Ryan, Rawan Shraim, Sarah K. Tasian, Tiffaney Vincent, Lauren Young, Yingying Zhang, Giuseppe Ciaramella, Jason Gehrke, David T. Teachey
Journal: Blood
Blood (2022) 140 (6): 619–629.
https://doi.org/10.1182/blood.2022015825
Published: 2022
Includes: Supplemental data
Journal Articles

Comprehensive Secretome Profiling Elucidates Novel Disease Biology and Identifies Pre-Infusion Candidate Biomarkers to Predict the Development of Severe Cytokine Release Syndrome in Pediatric Patients Receiving CART19

Caroline Diorio, Rawan Shraim, Regina M. Myers, Chakkapong Burudpakdee, Allison Barz Leahy, Richard Aplenc, Michele P. Lambert, Hamid Bassiri, Edward M Behrens, Vanessa E. Gonzalez, Fang Chen, Bruce L Levine, Shannon L. Maude, Amanda M. DiNofia, Alix E. Seif, J. Joseph Melenhorst, Simon F Lacey, Carl H June, David Barrett, Stephan A. Grupp, David T. Teachey
Journal: Blood
Blood (2021) 138 (Supplement 1): 167.
https://doi.org/10.1182/blood-2021-149477
Published: 2021
Journal Articles

Treatment Resistance in ETP-ALL Is Associated with Progenitor-like Arrest State

Changya Chen, Jason Xu, Tiffaney Vincent, Chia-hui Chen, Elizabeth Li, Yusha Sun, Jackie Peng, Rawan Shraim, Anusha Thadi, Sydney D'Amaddio, David Teachey, Kai Tan
Journal: Blood
Blood (2021) 138 (Supplement 1): 618.
https://doi.org/10.1182/blood-2021-153291
Published: 2021