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Journal Articles

A Cibersortx Signature Predicts Outcome in Pediatric AML Patients

Francisco Marchi, Fernando Sckaff, Xueyuan Cao, Raul C. Ribeiro, Jeffrey E. Rubnitz, Stanley B. Pounds, Jatinder K. Lamba
Journal: Blood
Blood (2022) 140 (Supplement 1): 3441–3442.
https://doi.org/10.1182/blood-2022-163366
Published: 2022
Journal Articles

Proteomic Analysis Identifies Epigenetic Modifiers and Potential Negative Regulators of Leukemogenesis KMD6A and SETDB1 to be Induced Post In Vivo Decitabine Exposure in Pediatric AML

Jatinder K. Lamba, Xueyuan Cao, Huiyun Wu, Hiroto Inaba, Raul C. Ribeiro, Junmin Peng, Tanja A. Gruber, Jeffrey E. Rubnitz, Stanley B. Pounds
Journal: Blood
Blood (2022) 140 (Supplement 1): 6086–6087.
https://doi.org/10.1182/blood-2022-166671
Published: 2022
Journal Articles

Integrated Gene Expression Analysis Identifies ETS2 Involved in Oncogene Induced Senescence to be Associated with Poor Outcome in Paediatric AML

Phani Krishna Parcha, Xueyuan Cao, Jeffrey E. Rubnitz, Raul C. Ribeiro, Stanley B. Pounds, Jatinder K. Lamba
Journal: Blood
Blood (2022) 140 (Supplement 1): 11781–11782.
https://doi.org/10.1182/blood-2022-163689
Published: 2022
Journal Articles

Comprehensive Genome Characterization of Childhood T-ALL Links Oncogene Activation Mechanism and Subtypes to Prognosis

Petri Pölönen, Abdelrahman Elsayed, Danika Di Giacomo, Lindsey Montefiori, Shunsuke Kimura, Jason Myers, Dale Hedges, Jason Xu, Yawei Hui, Zhongshan Cheng, Yiping Fan, Ilaria Iacobucci, Yunchao Chang, Rawan Shraim, Meenakshi Devidas, Stuart S. Winter, Kimberly P. Dunsmore, Jun J.J. Yang, Tiffaney L. Vincent, Kai Tan, Changya Chen, Haley Newman, Mignon L. Loh, Elizabeth A. Raetz, Stephen P. Hunger, Evadnie Rampersaud, Ti-Cheng Chang, Gang Wu, Stanley B. Pounds, Charles G. Mullighan, David T. Teachey
Journal: Blood
Blood (2022) 140 (Supplement 1): 1727–1729.
https://doi.org/10.1182/blood-2022-167157
Published: 2022
Journal Articles

Progenitor Sub-Populations in Treatment Resistant T-ALL

Jason Xu, Changya Chen, Tiffaney L. Vincent, Petri Pölönen, Abdelrahman Elsayed, Jianzhong Hu, Satoshi Yoshimura, Wenbao Yu, Chia-hui Chen, Elizabeth Li, Rawan Shraim, Marieke Lavaert, Haley Newman, Yang-yang Ding, Anusha Thadi, Kyung Jin Ahn, Jacqueline Peng, Chujie Gong, Yusha Sun, Shovik Bandyopadhyay, David Frank, Mignon L. Loh, Elizabeth A. Raetz, Zhiguo Chen, Brent L. Wood, Meenakshi Devidas, Kimberly P. Dunsmore, Stuart S. Winter, Gang Wu, Avinash Bhandoola, Stanley B. Pounds, Stephen P. Hunger, Jun J. Yang, Charles G. Mullighan, David T. Teachey, Kai Tan
Journal: Blood
Blood (2022) 140 (Supplement 1): 1724–1726.
https://doi.org/10.1182/blood-2022-166521
Published: 2022
Journal Articles

Genome-Wide Association Study Identifies Variants Associated with Clinical Outcomes in Pediatric Patients with Newly Diagnosed Acute Myeloid Leukemia

Richard J Marrero, Xueyuan Cao, Huiyun Wu, Hiroto Inaba, Susana C. Raimondi, Ching-Hon Pui, Raul C. Ribeiro, Jeffrey E. Rubnitz, Stanley B. Pounds, Jatinder K. Lamba
Journal: Blood
Blood (2022) 140 (Supplement 1): 6295–6296.
https://doi.org/10.1182/blood-2022-159534
Published: 2022
Journal Articles

A Transcriptional Classifier Identifies Pediatric T-Cell Acute Lymphoblastic Leukemias at High Risk for End of Induction Minimal Residual Disease

Lauren K. Meyer, Ritu P. Roy, Petri Pölönen, Abdelrahman Elsayed, Benjamin J. Huang, Shunsuke Kimura, Cristina Delgado-Martin, Tiffaney L. Vincent, Theresa Ryan, Brent L. Wood, Zhiguo Chen, Yu Liu, Jinghui Zhang, Terzah M. Horton, Mignon L. Loh, Meenakshi Devidas, Elizabeth A. Raetz, Robert J. Hayashi, Stuart S. Winter, Kimberly P. Dunsmore, Stephen P. Hunger, Stanley B. Pounds, Michelle L. Hermiston, Jun J. Yang, Charles G. Mullighan, David T. Teachey, Adam B. Olshen
Journal: Blood
Blood (2022) 140 (Supplement 1): 1722–1723.
https://doi.org/10.1182/blood-2022-165233
Published: 2022
Journal Articles

Single-Cell Pan-Cancer Analysis Reveals Treatment Resistance Stem/Progenitor-like Subpopulation in the High-Risk Pediatric Leukemia

Changya Chen, Jason Xu, Tiffaney L. Vincent, Wenbao Yu, Yang Y Ding, Chia-hui Chen, Samuel Kim, Elizabeth Li, Shovik Bandyopadhyay, Petri Pölönen, Abdelrahman Elsayed, Haley Newman, Brent L. Wood, Jianzhong Hu, Rawan Shraim, Mignon L. Loh, Elizabeth A. Raetz, Stephen P. Hunger, Stanley B. Pounds, Jun J. Yang, Charles G. Mullighan, David Frank, Kathrin M. Bernt, David T. Teachey, Kai Tan
Journal: Blood
Blood (2022) 140 (Supplement 1): 1273–1274.
https://doi.org/10.1182/blood-2022-167057
Published: 2022
Journal Articles

Genome-Wide CRISPR/Cas9 Screen Identifies AraC-Daunorubicin-Etoposide (ADE) Response Modulators Associated with Clinical Outcomes in Pediatric AML

Nam H.K. Nguyen, Abderrahmane Tagmount, Jeffrey E. Rubnitz, Raul C. Ribeiro, Xueyuan Cao, Stanley B. Pounds, Chris D. Vulpe, Jatinder K. Lamba
Journal: Blood
Blood (2022) 140 (Supplement 1): 5947–5948.
https://doi.org/10.1182/blood-2022-159322
Published: 2022
Journal Articles

Personalization of Induction Therapy for Pediatric AML to Ara-C+Dauno+ Etoposide (ADE) or Clofarabine+Ara-C According to a Polygenic Ara-C SNP Score- ACS10

Jatinder K. Lamba, Richard J Marrero, Abdelrahman H Elsayed, Xueyuan Cao, Huiyun Wu, Hiroto Inaba, Susana C. Raimondi, Ching-Hon Pui, Raul C. Ribeiro, Jeffrey E. Rubnitz, Stanley B. Pounds
Journal: Blood
Blood (2022) 140 (Supplement 1): 1039–1040.
https://doi.org/10.1182/blood-2022-159657
Published: 2022
Journal Articles

The Influence of Genetic Ancestry on Disease Biology in Pediatric T-Cell Acute Lymphoblastic Leukemia

Haley Newman, Shawn Lee, Petri Pölönen, Rawan Shraim, Yimei Li, Hongyan Liu, Tiffaney L. Vincent, Richard Aplenc, Changya Chen, Zhiguo Chen, Caroline Diorio, Kimberly P. Dunsmore, Sumit Gupta, Gang Wu, Kai Tan, Meenakshi Devidas, Stuart S. Winter, Brent L. Wood, Lena E. Winestone, Jason Xu, Elizabeth A. Raetz, Mignon L. Loh, Stephen P. Hunger, Stanley B. Pounds, Kira O Bona, Charles G. Mullighan, Jun J. Yang, David T. Teachey
Journal: Blood
Blood (2022) 140 (Supplement 1): 3458–3460.
https://doi.org/10.1182/blood-2022-159159
Published: 2022
Journal Articles

Integrated Genomic Analysis Identifies UBTF Tandem Duplications As a Subtype-Defining Lesion in Pediatric Acute Myeloid Leukemia

Masayuki Umeda, Jing Ma, Benjamin J. Huang, Kohei Hagiwara, Tamara Westover, Sherif Abdelhamed, Juan Martin Barajas, Melvin Edward Thomas, III, Michael P Walsh, Guangchun Song, Liqing Tian, Yanling Liu, Xiaolong Chen, Pandurang Kolekar, Quang Tran, Scott Foy, Jamie L. Maciaszek, Andrew B Kleist, Amanda R. Leonti, Bensheng Ju, John Easton, Huiyun Wu, Virginia Valentine, Marc Valentine, Yen-Chun Liu, Rhonda E. Ries, Jenny L. Smith, Evan Parganas, Ilaria Iacobucci, Ryan Hiltenbrand, Jonathan Miller, Jason Myers, Evadnie Rampersaud, Delaram Rahbarinia, Michael Rusch, Gang Wu, Hiroto Inaba, Yi-Cheng Wang, Todd A. Alonzo, James R. Downing, Charles G. Mullighan, Stanley B Pounds, M. Madan Babu, Jinghui Zhang, Jeffrey E. Rubnitz, Soheil Meshinchi, Xiaotu Ma, Jeffery M. Klco
Journal: Blood
Blood (2021) 138 (Supplement 2): LBA-4.
https://doi.org/10.1182/blood-2021-155134
Published: 2021
Journal Articles

Impact of SAMHD1 Pharmacogenetics on Clinical Outcome in Pediatric AML

Richard J Marrero, Abdelrahman H Elsayed, Xueyuan Cao, Huiyun Wu, Lei Wang, Raul C Ribeiro, Jeffrey E. Rubnitz, Stanley B Pounds, Jatinder K. Lamba
Journal: Blood
Blood (2021) 138 (Supplement 1): 3429.
https://doi.org/10.1182/blood-2021-147528
Published: 2021
Journal Articles

Clinical Features and Cytoreduction Therapy in Children with Newly Diagnosed Acute Myeloid Leukemia and Hyperleukocytosis

Georgios E. Christakopoulos, Kendra N Walker, Lei Wang, Clifford Takemoto, Yan Zheng, Ching-Hon Pui, Raul C Ribeiro, Stanley B Pounds, Jeffrey E. Rubnitz, Hiroto Inaba
Journal: Blood
Blood (2021) 138 (Supplement 1): 2295.
https://doi.org/10.1182/blood-2021-151045
Published: 2021
Journal Articles

Clinical Activity, Pharmacokinetics, and Pharmacodynamics of Sorafenib In Pediatric Acute Myeloid Leukemia.

Hiroto Inaba, MD, PhD, Jeffrey E Rubnitz, MD, PhD, Elaine Coustan-Smith, MS, Lie Li, Brian D Furmanski, PhD, Gerard P Mascara, Sheila A Shurtleff, PhD, Stanley B Pounds, PhD, Ching-Hon Pui, MD, Raul C Ribeiro, MD, Dario Campana, MD, PhD, Sharyn D Baker, PharmD, PhD
Journal: Blood
Blood (2010) 116 (21): 1073.
https://doi.org/10.1182/blood.V116.21.1073.1073
Published: 2010
Journal Articles

High-Resolution Genome-Wide Profiling of DNA Copy Number Abnormalities and Gene Resequencing in Pediatric Acute Myeloid Leukemia (AML).

Ina Radtke, PhD, Charles G. Mullighan, MD, PhD, Masami Ishii, MD, PhD, Jing Ma, PhD, Xiaoping Su, PhD, Salil Goorha, MD, Ramapriya Ganti, PhD, Zhongling Cai, Letha A. Phillips, Stanley B. Pounds, PhD, James Dalton, Susana C. Raimondi, PhD, Jeffrey E. Rubnitz, MD, PhD, Raul C. Ribeiro, MD, Sheila A. Shurtleff, PhD, James R. Downing, MD
Journal: Blood
Blood (2007) 110 (11): 103.
https://doi.org/10.1182/blood.V110.11.103.103
Published: 2007
Journal Articles

Genome-Wide Profiling of DNA Copy Number Abnormalities and Loss-Of-Heterozygosity in Pediatric Acute Myeloid Leukemia Using High-Resolution Single Nucleotide Polymorphism Microarrays.

Ina Radtke, PhD, Charles G. Mullighan, MBBS, MSc, MD, Salil Goorha, MD, Jing Ma, PhD, Stanley B. Pounds, PhD, Xiaoping Su, PhD, Alyssa L. Kennedy, Susanna M. Downing, Jeffrey E. Rubnitz, MD, PhD, Raul C. Ribeiro, MD, Sheila A. Shurtleff, PhD, James R. Downing, MD
Journal: Blood
Blood (2006) 108 (11): 106.
https://doi.org/10.1182/blood.V108.11.106.106
Published: 2006
Journal Articles

High Resolution Genomic Profiling Using Single Nucleotide Polymorphism Microarrays Identifies Multiple Novel Genomic Lesions in Pediatric Acute Lymphoblastic Leukemia.

Charles G. Mullighan, MBBS, MD, Salil Goorha, MD, Ina Radtke, MD, James Dalton, BS, Jing Ma, PhD, Stanley B. Pounds, PhD, Xiaoping Su, PhD, Ching-Hon Pui, MD, Mary V. Relling, PharmD, William E. Evans, PharmD, James R. Downing, MD
Journal: Blood
Blood (2006) 108 (11): 108.
https://doi.org/10.1182/blood.V108.11.108.108
Published: 2006
Journal Articles

Genes Regulating B-Cell Development and Differentiation Are Mutated in 40% of Pediatric Acute Lymphoblastic Leukemia.

Charles G. Mullighan, MBBS, MSc, MD, Salil Goorha, MD, Ina Radtke, MD, Christopher B. Miller, Elaine Coustan-Smith, James D. Dalton, Kevin Girtman, Susan Mathew, PhD, Jing Ma, PhD, Stanley B. Pounds, PhD, Xiaoping Su, PhD, Ching-Hon Pui, MS, Mary V. Relling, PharmD, William E. Evans, PharmD, Sheila A. Shurtleff, PhD, James R. Downing, MD
Journal: Blood
Blood (2006) 108 (11): 217.
https://doi.org/10.1182/blood.V108.11.217.217
Published: 2006
Journal Articles

Effect of Age on Prognosis in Childhood Acute Myeloid Leukemia.

Bassem I. Razzouk, MD, Elihu Estey, MD, Stanley B. Pounds, Ph.D, Shelly Lensing, MS, Sherry Pierce, MS, Mark Brandt, MS, Jeffrey E. Rubnitz, MD, Raul C. Ribeiro, MD, Michael Rytting, MD, Ching-Hon Pui, MD, Hagop M. Kantarjian, MD, Sima C. Jeha, MD
Journal: Blood
Blood (2004) 104 (11): 1064.
https://doi.org/10.1182/blood.V104.11.1064.1064
Published: 2004