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Journal Articles

BMS-986158, a Potent BET Inhibitor, in Combination with Ruxolitinib or Fedratinib in Patients (pts) with Intermediate- or High-Risk Myelofibrosis (MF): Updated Results from a Phase 1/2 Study

David Lavie, Vincent Ribrag, Michael Loschi, Costas K. Yannakou, Maan Alwan, Adi Schacham Abulafia, Jesús María Hernández-Rivas, Yulia Volchek, Chun Yew Fong, Massimiliano Bonifacio, Jean-Jacques Kiladjian, Jean-Christophe Ianotto, Valentín García Gutiérrez, Alessandra Tucci, Blanca Xicoy, Haifa Kathrin Al-Ali, Moshe Talpaz, Jonathan M. Gerber, Indu Raman, Ciprian Tomuleasa, Si Tuen Lee-Hoeflich, Sharmila Das, Bin Wu, Qian Zhao, Eunhee Kim, Oriana Esposito, Yu Liu, Zariana Nikolova, Christopher Tehlirian, Shodeinde Coker, Rosa Ayala
Journal: Blood
Blood (2023) 142 (Supplement 1): 623.
https://doi.org/10.1182/blood-2023-179160
Published: 2023
Journal Articles

Comparing Phenotyping, Gene Expression, and Function of T Lymphocytes before Mobilization Chemotherapy Versus after Stem Cell Harvesting in Patients with B Cell Lymphoma and Multiple Myeloma

Sheng-Hsuan Chien, Xiuli Wang, Wen-Chun Chen, Chun-Yu Liu
Journal: Blood
Blood (2023) 142 (Supplement 1): 2147.
https://doi.org/10.1182/blood-2023-173443
Published: 2023
Journal Articles

Preclinical Study of DZD8586, a Non-Covalent LYN/BTK Dual Inhibitor with Excellent BBB Penetration, for the Treatment of B-Cell Non-Hodgkin Lymphoma (B-NHL)

Yu Bai, Ting Wu, Minghui Hu, Sufang Han, Yu Liu, Jie Zheng, Junjun Qin, Lin Zhang, Zhenfan Yang
Journal: Blood
Blood (2023) 142 (Supplement 1): 2822.
https://doi.org/10.1182/blood-2023-185156
Published: 2023
Journal Articles

AML1-ETO and CCND2 Overexpression Cooperate to Drive AML Initiation and Progression

Junli Mou, Yu Liu, Xiaoyu Liu, Runxia Gu, Yingxi Xu, Kejing Tang, Zheng Tian, Haiyan Xing, Qing Rao, Min Wang, Shaowei Qiu, Jianxiang Wang
Journal: Blood
Blood (2023) 142 (Supplement 1): 4129.
https://doi.org/10.1182/blood-2023-179869
Published: 2023
Journal Articles

CRISPR-Cas9 Screening Identifies Therapeutic Targets for AML1-ETO Positive Leukemia

Chengcai Guo, Yu Liu, Qing Rao, Shaowei Qiu, Runxia Gu, Min Wang, Jianxiang Wang
Journal: Blood
Blood (2023) 142 (Supplement 1): 5697.
https://doi.org/10.1182/blood-2023-179262
Published: 2023
Journal Articles

Modulation of Biomarkers By BET Inhibitor, BMS-986158, Including JAK2 Variant Allele Frequency (VAF), Bone Marrow (BM) Fibrosis, and Reversal of Abnormal Cytokine Production in Intermediate- or High-Risk Myelofibrosis (MF)

Si Tuen Lee-Hoeflich, Christopher Brueckner, Lawrence Litalien, Ke Xu, Sharmila Das, Laura Corella, Sherif Daouti, Oriana Esposito, Emma Lees, Yu Liu, Zariana Nikolova, Christopher Tehlirian, Shodeinde Coker, Bin Wu
Journal: Blood
Blood (2023) 142 (Supplement 1): 3158.
https://doi.org/10.1182/blood-2023-181620
Published: 2023
Journal Articles

IKZF2 Specifically Participates in AML1-ETO Mediated Blockage of Myeloid Differentiation

Yu Liu, Chengcai Guo, Wenbing Liu, Xiaoyu Liu, Qing Rao, Runxia Gu, Shaowei Qiu, Min Wang, Jianxiang Wang
Journal: Blood
Blood (2023) 142 (Supplement 1): 2750.
https://doi.org/10.1182/blood-2023-179854
Published: 2023
Journal Articles

Genomic Landscape of Pediatric Non-Down's Syndrome Acute Megakaryoblastic Leukemia in China

Kefei Wu, Hui Liu, Yangyang Xie, Yuhan Liu, Bowen Cui, Jiaoyang Cai, Ronghua Wang, Yong Wang, Xiang Wang, Xiaoxiao Chen, Shuang Zhao, Ting Liu, Han Wang, Wenyan Wu, Huiying Sun, Jian'an Rao, Lan Wang, Jing Chen, Jing Chen, Benshang Li, Yu Liu, Wenting Hu, Shuhong Shen
Journal: Blood
Blood (2023) 142 (Supplement 1): 4331.
https://doi.org/10.1182/blood-2023-181798
Published: 2023
Journal Articles

Thrombosis Caused By a Novel Coagulation Factor IX Mutation (FIX Shanghai II)

Wenman WU, Rui Wang, Qin Xu, Guanzheng Wang, Shifeng Jiang, Can Lou, Xi Wu, Yanyan Shao, Yeling Lu, Yu Liu, Guanquan Xu, Qiulan Ding, Xiaobo Hu, Xuefeng Wang, Jing Dai
Journal: Blood
Blood (2023) 142 (Supplement 1): 1233.
https://doi.org/10.1182/blood-2023-184596
Published: 2023
Journal Articles

Prognostic Features of CD9 in Childhood Acute Lymphoblastic Leukemia - a Retrospective Analysis of a Nation-Wide Multicenter Study in China

Kathy Yuen Yee Chan, Jiaoyang Cai, Yu Liu, Jun J. Yang, Ching-Hon Pui, Shuhong Shen, Chi Kong Li, Kam Tong Leung
Journal: Blood
Blood (2023) 142 (Supplement 1): 2836.
https://doi.org/10.1182/blood-2023-191098
Published: 2023
Journal Articles

Identifying STRN3-RARA as a new fusion gene for acute promyelocytic leukemia

Qi Zhang, He Li, Xuelan Chen, Fan Gu, Lanxin Zhang, Lu Zhang, Tong Chen, Qiang Chen, Wentong Meng, Yu Wu, Hong Chang, Ting Liu, Chong Chen, Hongbing Ma, Yu Liu
Journal: Blood
Blood (2023) 142 (17): 1494–1499.
https://doi.org/10.1182/blood.2023020619
Published: 2023
Includes: Supplemental data
Journal Articles

Preliminary Safety and Efficacy of Bgb-11417, a Novel Bcl-2 Inhibitor, in Combination with Azacitidine in Patients with Acute Myeloid Leukemia (AML)

Jake Shortt, Pau Montesinos, Shuh Ying Tan, Teng Fong Ng, Chun Yew Fong, Paul Cannell, Rajeev Rajagopal, Sophia Leitch, Peter T. Tan, Sundra Ramanathan, Robin Gasiorowski, Douglas Stuart Lenton, Tse-Chieh Teh, José Antonio Pérez-Simón, Carolyn Grove, Xiaojun Huang, Courtney D. DiNardo, Katherine Naidu, Joseph Pariseau, Si Cheng, Yu Liu, Melannie Co, Wai Y. Chan, Haiyi Guo, Andrew H. Wei
Journal: Blood
Blood (2022) 140 (Supplement 1): 3329–3332.
https://doi.org/10.1182/blood-2022-166937
Published: 2022
Journal Articles

KMT2D Deficiency Promotes Myeloid Leukemias through Regulating Ribosome Biogenesis

Jing Xu, Ailing Zhong, Chong Chen, Yu Liu, Ting Niu
Journal: Blood
Blood (2022) 140 (Supplement 1): 5855–5856.
https://doi.org/10.1182/blood-2022-168509
Published: 2022
Journal Articles

A Transcriptional Classifier Identifies Pediatric T-Cell Acute Lymphoblastic Leukemias at High Risk for End of Induction Minimal Residual Disease

Lauren K. Meyer, Ritu P. Roy, Petri Pölönen, Abdelrahman Elsayed, Benjamin J. Huang, Shunsuke Kimura, Cristina Delgado-Martin, Tiffaney L. Vincent, Theresa Ryan, Brent L. Wood, Zhiguo Chen, Yu Liu, Jinghui Zhang, Terzah M. Horton, Mignon L. Loh, Meenakshi Devidas, Elizabeth A. Raetz, Robert J. Hayashi, Stuart S. Winter, Kimberly P. Dunsmore, Stephen P. Hunger, Stanley B. Pounds, Michelle L. Hermiston, Jun J. Yang, Charles G. Mullighan, David T. Teachey, Adam B. Olshen
Journal: Blood
Blood (2022) 140 (Supplement 1): 1722–1723.
https://doi.org/10.1182/blood-2022-165233
Published: 2022
Journal Articles

BMS-986158, a Potent BET Inhibitor, As Monotherapy and in Combination with Ruxolitinib or Fedratinib in Intermediate- or High-Risk Myelofibrosis: First Results from a Phase 1/2 Study

Rosa Ayala, Nieves Lopez, Adi Shacham Abulafia, Maan Alwan, Costas K. Yannakou, Indu Raman, Vincent Ribrag, Chun Yew Fong, Yulia Volchek, Massimiliano Bonifacio, Alessandra Tucci, Jean-Jacques Kiladjian, Henry Chang, Sharmila Das, Bin Wu, Palanikumar Ravindran, Vivian Shan, Guan Wang, Oriana Esposito, Yu Liu, Zariana Nikolova, Christopher Tehlirian, Shodeinde Coker, David Lavie
Journal: Blood
Blood (2022) 140 (Supplement 1): 9665–9667.
https://doi.org/10.1182/blood-2022-159476
Published: 2022
Journal Articles

Distinct Genomic Landscape of Chinese Pediatric Acute Myeloid Leukemia

Ting Liu, MD, Jianan Rao, Master, Wenting Hu, MD, Yuhan Liu, MD, Huiying Sun, Master, Xiaoxiao Chen, MD, Yanjing Tang, MDPhD, Jing Chen, MD, Xiang Wang, PhD, Han Wang, Master, Wubin Qian, PhD, Binchen Mao, PhD, Sheng Guo, PhD, Ronghua Wang, Master, Yu Liu, PhD, Shuhong Shen, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 38.
https://doi.org/10.1182/blood-2020-140150
Published: 2020
Journal Articles

CoupledCAR TM Technology for Treating Thyroid Cancer

Xingchen Liu, Lei Xiao, PhD, Keshu Zhou, Yu Liu, Yong Huang, Chengfei Pu, Zhiyuan Cao, Ruihong Zhu, Haiyang Tang, Zhipeng Huang, Hang Yang, Xi Huang, Yongping Song, Renbin Liu, Zhao Wu
Journal: Blood
Blood (2020) 136 (Supplement 1): 46.
https://doi.org/10.1182/blood-2020-138668
Published: 2020
Journal Articles

Nivolumab treatment of relapsed/refractory Epstein-Barr virus–associated hemophagocytic lymphohistiocytosis in adults

Clinical Trials & Observations
Pengpeng Liu, Xiangyu Pan, Chong Chen, Ting Niu, Xiao Shuai, Jian Wang, Xuelan Chen, Jiazhuo Liu, Yong Guo, Liping Xie, Yu Wu, Yu Liu, Ting Liu
Journal: Blood
Blood (2020) 135 (11): 826–833.
https://doi.org/10.1182/blood.2019003886
Published: 2020
Includes: Supplemental data
Journal Articles

Therapy-induced mutations drive the genomic landscape of relapsed acute lymphoblastic leukemia

Benshang Li, Samuel W. Brady, Xiaotu Ma, Shuhong Shen, Yingchi Zhang, Yongjin Li, Karol Szlachta, Li Dong, Yu Liu, Fan Yang, Ningling Wang, Diane A. Flasch, Matthew A. Myers, Heather L. Mulder, Lixia Ding, Yanling Liu, Liqing Tian, Kohei Hagiwara, Ke Xu, Xin Zhou, Edgar Sioson, Tianyi Wang, Liu Yang, Jie Zhao, Hui Zhang, Ying Shao, Hongye Sun, Lele Sun, Jiaoyang Cai, Hui-Ying Sun, Ting-Nien Lin, Lijuan Du, Hui Li, Michael Rusch, Michael N. Edmonson, John Easton, Xiaofan Zhu, Jingliao Zhang, Cheng Cheng, Benjamin J. Raphael, Jingyan Tang, James R. Downing, Ludmil B. Alexandrov, Bin-Bing S. Zhou, Ching-Hon Pui, Jun J. Yang, Jinghui Zhang
Journal: Blood
Blood (2020) 135 (1): 41–55.
https://doi.org/10.1182/blood.2019002220
Published: 2020
Includes: Supplemental data
Journal Articles

The Genomic Landscape of Childhood Acute Lymphoblastic Leukemia

Kathryn G. Roberts, PhD, Samuel W. Brady, PhD, Zhaohui Gu, PhD, Lei Shi, PhD, Stanley Pounds, PhD, Deqing Pei, MS, Cheng Cheng, PhD, Yunfeng Dai, PhD, Meenakshi Devidas, PhD, Chunxu Qu, PhD, Ashley Hill, BS, Xiaotu Ma, Lei Wei, PhD, Sasi Arunachalam, PhD, Kohei Hagiwara, MD, Yangling Liu, Diane Flasch, Yu Liu, PhD, Matthew Parker, PhD, Xiaolong Chen, PhD, Yongjin Li, PhD, Yiping Fan, PhD, Robert Michael, PhD, Michael Rusch, BS, Mark Wilkinson, Scott Foy, PhD, Dale Hedges, PhD, Scott Newman, PhD, Xin Zhou, PhD, Jian Wang, Shalini C. Reshmi, PhD, Julie M. Gastier-Foster, PhD, Patee Gesuwan, Malcolm A Smith, MD PhD, Daniela S. Gerhard, PhD, Naomi Winick, MD, Andrew J. Carroll, PhD, Nyla A. Heerema, PhD, Richard C. Harvey, PhD, Cheryl L. Willman, MD, Eric Larsen, MD, Elizabeth A. Raetz, MD, Michael J. Borowitz, MD PhD, Brent L Wood, MD PhD, William L. Carroll, MD, Patrick A. Zweidler-McKay, MD PhD, Karen R. Rabin, MD PhD, Leonard A. Mattano, MD, Kelly Maloney, MD, Stuart S. Winter, MD, Michael J. Burke, MD, Wanda L. Salzer, MD, Kimberly P. Dunsmore, Anne Angiolillo, MD, Kristine R Crews, PharmD, James R. Downing, MD, Sima Jeha, MD, William E. Evans, PharmD, Ching-Hon Pui, MD, Jun J. Yang, PhD, Mary V. Relling, PharmD, Stephen P. Hunger, MD, Mignon L. Loh, MD, Jinghui Zhang, PhD, Charles G. Mullighan, MBBS, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 649.
https://doi.org/10.1182/blood-2019-124881
Published: 2019