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Satoshi Yoshimura
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Journal Articles

STAT1-mediated interferon signatures associate with preclinical JAK-inhibitor sensitivity in T-cell acute lymphoblastic leukemia

Jason Xu, Jonathan H Sussman, Austin Yang, Satoshi Yoshimura, Jianzhong Hu, Changya Chen, Tiffaney L Vincent, Shovik Bandyopadhyay, Elizabeth Y Li, Tristan Lee Lim, Omar Elghawy, Adam Barsouk, Damjan Karanfilovski, Shira L Wald, Gregory M Chen, David Wei Wu, Haley Newman, Alexander Li, Yusha Sun, Chia-Hui Chen, Kathrin Maria Bernt, Brent L. Wood, Stuart Sheldon Winter, Kimberly P. Dunsmore, Elizabeth A. Raetz, Meenakshi Devidas, Stanley B Pounds, Mignon L. Loh, Stephen P Hunger, Mark Chiang, Caroline Diorio, Danika Di Giacomo, Petri Pölönen, Charles G. Mullighan, Jun J Yang, Kai Tan, David Trent Teachey
Journal: Blood
Blood blood.2025028566.
https://doi.org/10.1182/blood.2025028566
Published: 2025
Includes: Supplemental data
Journal Articles

Single-cell panleukemia signatures of HSPC-like blasts predict drug response and clinical outcome

Changya Chen, Jason Xu, Jonathan H Sussman, Tiffaney L Vincent, Joseph S Tumulty, Satoshi Yoshimura, Fatemeh Alikarami, Wenbao Yu, Yang-Yang Ding, Chia-Hui Chen, Elizabeth Y Li, Austin Yang, Xiaohuan Qin, Shovik Bandyopadhyay, Jacqueline Jiahui Peng, Petri Pölönen, Haley Newman, Brent Wood, Jianzhong Hu, Rawan Shraim, Andrew D Hughes, Caroline Diorio, Lahari Uppuluri, Gongping Shi, Theresa Ryan, Tori Fuller, Mignon L. Loh, Elizabeth A. Raetz, Stephen P Hunger, Stanley B Pounds, Charles G. Mullighan, David Frank, Jun J Yang, Kathrin Maria Bernt, David Trent Teachey, Kai Tan
Journal: Blood
Blood blood.2024027270.
https://doi.org/10.1182/blood.2024027270
Published: 2025
Includes: Supplemental data
Journal Articles

Interferon-Activated Gene Signatures Associate with Chemotherapy Resistance and Sensitivity to JAK-Inhibition in Refractory ETP-ALL

Jason Xu, Jonathan Sussman, Austin Yang, Satoshi Yoshimura, Changya Chen, Omar Elghawy, Tiffaney Vincent, Caroline Diorio, Shovik Bandyopadyay, Jianzhong Hu, Alexander Lai Li, Gregory M. Chen, Chia-Hui Chen, Rawan Shraim, Haley Newman, Yang Ding, Elizabeth Li, Wenbao Yu, Anusha Thadi, Kyung Jin Ahn, Petri Pölönen, Abdelrahman Elsayed, David Frank, Elizabeth A. Raetz, Mignon L. Loh, Brent L. Wood, Stuart S. Winter, Kimberly P. Dunsmore, Meenakshi Devidas, Chunxu Qu, Stanley Pounds, Stephen P. Hunger, Charles G. Mullighan, Jun J. Yang, Kai Tan, David T. Teachey
Journal: Blood
Blood (2024) 144 (Supplement 1): 1464.
https://doi.org/10.1182/blood-2024-211090
Published: 2024
Journal Articles

The Impact of Age and Genomics on Drug Sensitivity in 1,076 Children and Adults with B-Cell Acute Lymphoblastic Leukemia

Satoshi Yoshimura, Zhenhua Li, Yoshihiro Gocho, Wenjian Yang, Kristine R Crews, Shawn H.R. Lee, Kathryn G. Roberts, Charles G. Mullighan, Mary V. Relling, Federico Antillon-Klussmann, Allen Eng Juh Yeoh, Mignon L. Loh, Mark R. Litzow, Sima Jeha, Seth E. Karol, Hiroto Inaba, Ching-Hon Pui, Marina Y. Konopleva, Nitin Jain, Wendy Stock, Elisabeth Paietta, Elias Jabbour, Steven M. Kornblau, William E. Evans, Jun J. Yang
Journal: Blood
Blood (2023) 142 (Supplement 1): 596.
https://doi.org/10.1182/blood-2023-181788
Published: 2023
Journal Articles

Progenitor Sub-Populations in Treatment Resistant T-ALL

Jason Xu, Changya Chen, Tiffaney L. Vincent, Petri Pölönen, Abdelrahman Elsayed, Jianzhong Hu, Satoshi Yoshimura, Wenbao Yu, Chia-hui Chen, Elizabeth Li, Rawan Shraim, Marieke Lavaert, Haley Newman, Yang-yang Ding, Anusha Thadi, Kyung Jin Ahn, Jacqueline Peng, Chujie Gong, Yusha Sun, Shovik Bandyopadhyay, David Frank, Mignon L. Loh, Elizabeth A. Raetz, Zhiguo Chen, Brent L. Wood, Meenakshi Devidas, Kimberly P. Dunsmore, Stuart S. Winter, Gang Wu, Avinash Bhandoola, Stanley B. Pounds, Stephen P. Hunger, Jun J. Yang, Charles G. Mullighan, David T. Teachey, Kai Tan
Journal: Blood
Blood (2022) 140 (Supplement 1): 1724–1726.
https://doi.org/10.1182/blood-2022-166521
Published: 2022
Journal Articles

PAX5 Epigenetically Orchestrates CD58 Transcription and Modulates Blinatumomab Response in Acute Lymphoblastic Leukemia

Yizhen Li, Takaya Moriyama, Satoshi Yoshimura, Xuijie Zhao, Zhenhua LI, Xu Yang, Jacob A Steele, Shondra Miller, Elisabeth Paietta, Marina Konopleva, Jiyang Yu, Hiroto Inaba, Raul C Ribeiro, Ching-Hon Pui, Jun J. Yang
Journal: Blood
Blood (2022) 140 (Supplement 1): 1041–1042.
https://doi.org/10.1182/blood-2022-156746
Published: 2022
Journal Articles

Preclinical Pharmacokinetic and Pharmacodynamic Evaluation of Dasatinib and Ponatinib in Lck-Activated T-Cell Acute Lymphoblastic Leukemia

Satoshi Yoshimura, Jianzhong Hu, John C. Panetta, Guoqing Du, Lie Li, Ching-Hon Pui, Marina Konopleva, Nitin Jain, Jun J.J. Yang
Journal: Blood
Blood (2022) 140 (Supplement 1): 8840–8841.
https://doi.org/10.1182/blood-2022-169363
Published: 2022
Journal Articles

Development of Proteolytic Targeting Chimeras to Target Lck in T-Cell Acute Lymphoblastic Leukemia

Jianzhong Hu, Jamie Jarusiewicz, Jaeki Min, Lei Yang, Divyabharathi Chepyala, Marisa Actis, Lauren Rowland, Guoqing Du, Brandon Smart, Dylan Maxwell, Boer Xie, Satoshi Yoshimura, Junmin Peng, David Teachey, Zoran Rankovic, Jun J. Yang
Journal: Blood
Blood (2021) 138 (Supplement 1): 867.
https://doi.org/10.1182/blood-2021-147024
Published: 2021