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Journal Articles

Immunoglobulin variable gene diversity reflects distinct metabolic/signaling states and impacts measurable residual disease monitoring and clinical outcome in B cell acute lymphoblastic leukemia

Free
Carol Fries Simpson, Cameron Baker, Diana Adlowitz, Lik Wee Lee, Yuxuan Liu, Philip Rock, Kristin Murphy, Lovely Soni, Bin Zhang, Lucille Stuani, Astraea Jager, Hongyue Wang, Janice Spence, Helene McMurray, John Ashton, Meenakshi Devidas, Mignon Loh, Karen Rabin, David Teachey, Laurie Steiner, Brent Wood, Ilan Kirsch, Rachel Rau, Richard Burack, Kara Davis
Journal: Blood
Blood (2025) 146 (Supplement 1): 333.
https://doi.org/10.1182/blood-2025-333
Published: 2025
Journal Articles

Outcomes in children with NCI standard-risk b-acute lymphoblastic leukemia treated with intensified post-induction therapy: Results from Children's Oncology Group studies AALL0932 and AALL1131

Free
Ruth Wang'ondu, Anne Angiolillo, Meenakshi Devidas, Karen Rabin, Michael Borowitz, Brent Wood, Andrew Carroll, Nyla Heerema, Emily Hibbitts, Reuven Schore, William Carroll, Michael Burke, Wanda Salzer, Lia Gore, Naomi Winick, David Teachey, Elizabeth Raetz, Mignon Loh, Stephen Hunger, John Kairalla
Journal: Blood
Blood (2025) 146 (Supplement 1): 757.
https://doi.org/10.1182/blood-2025-757
Published: 2025
Journal Articles

Factors associated with central nervous system relapse after b-acute lymphoblastic leukemia: A Children's oncology group report

Free
Aman Wadhwa, Lingyun Ji, Alice Dang, Xinxin Xu, Meenakshi Devidas, John Kairalla, Mary Shago, Nyla Heerema, Andrew Carroll, Michael Borowitz, Brent Wood, Eric Larsen, Kelly Maloney, Reuven Schore, Wanda Salzer, Michael Burke, Stephen Hunger, David Teachey, Naomi Winick, Elizabeth Raetz, Mignon Loh, Deepa Bhojwani, Sumit Gupta
Journal: Blood
Blood (2025) 146 (Supplement 1): 762.
https://doi.org/10.1182/blood-2025-762
Published: 2025
Journal Articles

Clinical characteristics and outcomes of children with T-cell acute lymphoblastic leukemia harboring ABL-class fusions: A report from the ponte di legno consortium

Free
Thai Hoa Tran, Meenakshi Devidas, Leyna Xoi, Andishe Attarbaschi, Judith Boer, Gunnar Cario, Giovanni Cazzaniga, Gabriele Escherich, Yoshihiro Gocho, Mats Heyman, Stephen Hunger, Hiroto Inaba, Gabor Kovacs, Anthony Moorman, Charles Mullighan, Kjeld Schmiegelow, Jan Stary, Tomasz Szczepanski, David Teachey, Andrea Biondi, Mignon Loh, Rob Pieters, Sarah Elitzur
Journal: Blood
Blood (2025) 146 (Supplement 1): 761.
https://doi.org/10.1182/blood-2025-761
Published: 2025
Journal Articles

Blinatumomab mitigates the impact of traditional adverse prognosticators among children with standard risk b-acute lymphoblastic leukemia: Updated results of the Children's oncology group (COG) Trial AALL1731

Free
Sumit Gupta, Rachel Rau, John Kairalla, Karen Rabin, Cindy Wang, Anne Angiolillo, Sarah Alexander, Andrew Carroll, Susan Conway, Lia Gore, Ilan Kirsch, Holly Kubaney, Amanda Li, Jennifer McNeer, Olga Militano, Tamara Miller, Yvonne Moyer, Maureen O'Brien, Maki Okada, Shalini Reshmi, Mary Shago, Elizabeth Wagner, Naomi Winick, Brent Wood, Tara Haworth-Wright, Faraz Zaman, Gerhard Zugmaier, Sue Zupanec, Meenakshi Devidas, Stephen Hunger, David Teachey, Mignon Loh, Elizabeth Raetz
Journal: Blood
Blood (2025) 146 (Supplement 1): 758.
https://doi.org/10.1182/blood-2025-758
Published: 2025
Journal Articles

Outcomes in children and adolescents with down syndrome and B-lymphoblastic leukemia: A report from Children's oncology group study AALL1731

Free
Amanda Li, John Kairalla, Cindy Wang, Meenakshi Devidas, Olga Militano, Johann Hitzler, Anne Angiolillo, Michael Burke, Wanda Salzer, Stephen Hunger, Naomi Winick, David Teachey, Elizabeth Raetz, Mignon Loh, Sumit Gupta, Rachel Rau, Karen Rabin
Journal: Blood
Blood (2025) 146 (Supplement 1): 547.
https://doi.org/10.1182/blood-2025-547
Published: 2025
Journal Articles

Inadequate social support and household material hardship among children with pediatric acute lymphoblastic leukemia: A report from the Children's oncology group Trial AALL1731

Free
Selena Murcia Mendez, Morgan Paul, John Kairalla, Cindy Wang, Sunyu Kang, Sarah Alexander, Peter Cole, Iris Paltin, Rahela Aziz-Bose, Colleen Kelly, Haley Newman, Daniel Zheng, Mignon Loh, Elizabeth Raetz, Stephen Hunger, Meenakshi Devidas, David Teachey, Rachel Rau, Sumit Gupta, Kira Bona, Puja Umaretiya
Journal: Blood
Blood (2025) 146 (Supplement 1): 132.
https://doi.org/10.1182/blood-2025-132
Published: 2025
Journal Articles

Feasibility of collecting social determinants of health data in the frontline pediatric acute lymphoblastic leukemia (ALL) trial AALL1731: A report from the Children's oncology group

Free
Haley Newman, Morgan Paul, John Kairalla, Cindy Wang, Sunyu Kang, Sarah Alexander, Peter Cole, Iris Paltin, Colleen Kelly, Daniel Zheng, Rahela Aziz-Bose, Puja Umaretiya, Mignon Loh, Elizabeth Raetz, Stephen Hunger, Meenakshi Devidas, David Teachey, Rachel Rau, Sumit Gupta, Kira Bona
Journal: Blood
Blood (2025) 146 (Supplement 1): 2742.
https://doi.org/10.1182/blood-2025-2742
Published: 2025
Journal Articles

STAT1-mediated interferon signatures are associated with preclinical JAK inhibitor sensitivity in T-ALL

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Clinical Trials & Observations
Jason Xu, Jonathan H. Sussman, Austin Yang, Satoshi Yoshimura, Jianzhong Hu, Changya Chen, Tiffaney Vincent, Shovik Bandyopadhyay, Elizabeth Y. Li, Tristan Lim, Omar Elghawy, Adam Barsouk, Damjan Karanfilovski, Shira L. Wald, Gregory M. Chen, David Wu, Haley Newman, Alexander Li, Yusha Sun, Chia-Hui Chen, Kathrin Bernt, Brent L. Wood, Stuart S. Winter, Kimberly P. Dunsmore, Elizabeth Raetz, Meenakshi Devidas, Stanley Pounds, Mignon Loh, Stephen P. Hunger, Mark Y. Chiang, Caroline Diorio, Danika Di Giacomo, Petri Pölönen, Charles G. Mullighan, Jun J. Yang, Kai Tan, David T. Teachey
Journal: Blood
Blood (2025) 145 (23): 2793–2798.
https://doi.org/10.1182/blood.2025028566
Published: 2025
Includes: Supplemental data
Journal Articles

Interferon-Activated Gene Signatures Associate with Chemotherapy Resistance and Sensitivity to JAK-Inhibition in Refractory ETP-ALL

Free
Jason Xu, Jonathan Sussman, Austin Yang, Satoshi Yoshimura, Changya Chen, Omar Elghawy, Tiffaney Vincent, Caroline Diorio, Shovik Bandyopadyay, Jianzhong Hu, Alexander Lai Li, Gregory M. Chen, Chia-Hui Chen, Rawan Shraim, Haley Newman, Yang Ding, Elizabeth Li, Wenbao Yu, Anusha Thadi, Kyung Jin Ahn, Petri Pölönen, Abdelrahman Elsayed, David Frank, Elizabeth A. Raetz, Mignon L. Loh, Brent L. Wood, Stuart S. Winter, Kimberly P. Dunsmore, Meenakshi Devidas, Chunxu Qu, Stanley Pounds, Stephen P. Hunger, Charles G. Mullighan, Jun J. Yang, Kai Tan, David T. Teachey
Journal: Blood
Blood (2024) 144 (Supplement 1): 1464.
https://doi.org/10.1182/blood-2024-211090
Published: 2024
Journal Articles

Immunoglobulin Sequencing Biologically Distinguishes B-Lymphoblastic Lymphoma from Acute Lymphoblastic Leukemia and Reveals a Spectrum of Disease Dissemination across Clinical Stages

Free
Carol Fries Simpson, Lik Wee Lee, Hongyue Wang, Diana G. Adlowitz, Philip Rock, Brent L. Wood, Rachel E. Rau, Kara L. Davis, Anne Angiolillo, Meenakshi Devidas, David T. Teachey, Karen R Rabin, Birte Wistinghausen, Donald Barkauskas, Robert J. Hayashi, Richard Burack, Carl E Allen, Michelle L. Hermiston, Ilan R. Kirsch
Journal: Blood
Blood (2024) 144 (Supplement 1): 2838.
https://doi.org/10.1182/blood-2024-201634
Published: 2024
Journal Articles

Blinatumomab Added to Chemotherapy Improves Disease-Free Survival in Newly Diagnosed NCI Standard Risk Pediatric B-Acute Lymphoblastic Leukemia: Results from the Randomized Children's Oncology Group Study AALL1731

Free
Rachel E. Rau, Sumit Gupta, John A. Kairalla, Karen R Rabin, Anne Angiolillo, Cindy Wang, Andrew J. Carroll, Susan Conway, Meenakshi Devidas, Lia Gore, Ilan R. Kirsch, Holly R. Kubaney, Amanda M Li, Jennifer L. McNeer, Olga Militano, Yvonne Moyer, Maureen M. O'Brien, Maki Okada, Shalini C. Reshmi, Mary Shago, Elizabeth R. Wagner, Naomi J. Winick, Brent L. Wood, Faraz Zaman, Gerhard Zugmaier, Sue Zupanec, Stephen P. Hunger, David T. Teachey, Elizabeth A. Raetz, Mignon L. Loh
Journal: Blood
Blood (2024) 144 (Supplement 1): 1.
https://doi.org/10.1182/blood-2024-207450
Published: 2024
Journal Articles

Prognostic Impact of t(1;19) in Pediatric B-Cell Acute Lymphoblastic Leukemia (B-ALL) Patients Treated on Contemporary Children's Oncology Group (COG) Protocols

Free
Ashley Pinchinat, John A. Kairalla, Meenakshi Devidas, Andrew J. Carroll, Mary Shago, Anne Angiolillo, Michael J. Burke, Wanda L. Salzer, Naomi J. Winick, Mignon L. Loh, David T. Teachey, Elizabeth A. Raetz, Karen R Rabin, Rachel E. Rau, Sumit Gupta
Journal: Blood
Blood (2024) 144 (Supplement 1): 315.
https://doi.org/10.1182/blood-2024-198507
Published: 2024
Journal Articles

Genomic Biomarkers of Poor Outcome in Patients with T-Cell Lymphoblastic Lymphoma

Free
Haley Newman, Lahari Uppuluri, Rawan Shraim, Carl E Allen, Kara L. Davis, Meenakshi Devidas, Caroline Diorio, Kimberly P. Dunsmore, Amira Elhachimi, David Frank, Lia Gore, Thomas Gross, Robert J. Hayashi, Terzah M. Horton, Andrew Hughes, Stephen P. Hunger, John Kim, Yimei Li, Stephanie Si Lim, Mignon L. Loh, Charles G. Mullighan, Adam B. Olshen, Petri Pölönen, Rachel E. Rau, Gongping Shi, Kai Tan, Tiffaney Vincent, Stuart S. Winter, Birte Wistinghausen, Brent L. Wood, Jason Xu, Jun J. Yang, Rodney R. Miles, Michelle L. Hermiston, David T. Teachey
Journal: Blood
Blood (2024) 144 (Supplement 1): 313.
https://doi.org/10.1182/blood-2024-203827
Published: 2024
Journal Articles

Utility of a Second Interim Maintenance Phase to Improve Outcomes for Pediatric Acute Lymphoblastic Leukemia: A Report from the Children's Oncology Group

Free
Etan Orgel, Michael J. Burke, John A. Kairalla, Emily Hibbitts, Meenakshi Devidas, Michael J. Borowitz, Brent L. Wood, Nyla A. Heerema, Andrew J. Carroll, Kelly Maloney, Leonard A. Mattano, Anne Angiolillo, Eric C. Larsen, Wanda L. Salzer, David T. Teachey, Naomi J. Winick, William L. Carroll, Stephen P. Hunger, Elizabeth A. Raetz, Mignon L. Loh
Journal: Blood
Blood (2024) 144 (Supplement 1): 2813.
https://doi.org/10.1182/blood-2024-194872
Published: 2024
Journal Articles

Examining Disparities By Race, Ethnicity, and Socioeconomic Factors in Children and Young Adults with Relapsed Acute Lymphoblastic Leukemia: A Report from the Children's Oncology Group

Free
John A Ligon, Deepa Bhojwani, Alice Dang, Lingyun Ji, Susan R Rheingold, Xinxin Xu, Meenakshi Devidas, John A. Kairalla, Mary Shago, Nyla A. Heerema, Andrew J. Carroll, Michael J. Borowitz, Brent L. Wood, Naomi J. Winick, William L. Carroll, Stephen P. Hunger, Elizabeth A. Raetz, Mignon L. Loh, Sumit Gupta, Lena E Winestone
Journal: Blood
Blood (2024) 144 (Supplement 1): 2797.
https://doi.org/10.1182/blood-2024-193893
Published: 2024
Journal Articles

Additional Induction Intrathecal Cytarabine for Patients with CNS2 Disease at Diagnosis Is Not Beneficial for Patients with B-ALL Treated on Children's Oncology Group Protocols AALL0932 and AALL1131

Free
Cathy A. Lee-Miller, John A. Kairalla, Emily Hibbitts, Naomi J. Winick, Anne Angiolillo, Reuven J. Schore, Wanda L. Salzer, Michael J. Burke, Mignon L. Loh, Elizabeth A. Raetz, Stephen P. Hunger, Meenakshi Devidas, David T. Teachey, Sumit Gupta, Jennifer L. McNeer
Journal: Blood
Blood (2024) 144 (Supplement 1): 4195.
https://doi.org/10.1182/blood-2024-203456
Published: 2024
Journal Articles

Germ line genetic NBN variation and predisposition to B-cell acute lymphoblastic leukemia in children

Free
Carolin S. Escherich, Wenan Chen, Yizhen Li, Wenjian Yang, Rina Nishii, Zhenhua Li, Elizabeth A. Raetz, Meenakshi Devidas, Gang Wu, Kim E. Nichols, Hiroto Inaba, Ching-Hon Pui, Sima Jeha, Bruce M. Camitta, Eric Larsen, Stephen P. Hunger, Mignon L. Loh, Jun J. Yang
Journal: Blood
Blood (2024) 143 (22): 2270–2283.
https://doi.org/10.1182/blood.2023023336
Published: 2024
Includes: Supplemental data
Journal Articles

MRD at the end of induction and EFS in T-cell lymphoblastic lymphoma: Children’s Oncology Group trial AALL1231

Free
CME Clinical Trials & Observations Brief Report
Robert J. Hayashi, Michelle L. Hermiston, Brent L. Wood, David T. Teachey, Meenakshi Devidas, Zhiguo Chen, Robert D. Annett, Barbara L. Asselin, Keith August, Steve Cho, Kimberly P. Dunsmore, Jason Lawrence Freedman, Paul J. Galardy, Paul Harker-Murray, Terzah M. Horton, Alok Jaju, Allison Lam, Yoav H. Messinger, Rodney R. Miles, Maki Okada, Samir Patel, Eric S. Schafer, Tal Schechter, Kristin A. Shimano, Neelam Singh, Amii Steele, Maria L. Sulis, Sarah L. Vargas, Stuart S. Winter, Charlotte Wood, Patrick A. Zweidler-McKay, Mignon L. Loh, Stephen P. Hunger, Elizabeth A. Raetz, Catherine M. Bollard, Carl E. Allen
Journal: Blood
Blood (2024) 143 (20): 2053–2058.
https://doi.org/10.1182/blood.2023021184
Published: 2024
Includes: Supplemental data
Journal Articles

Prognostic significance of ETP phenotype and minimal residual disease in T-ALL: a Children’s Oncology Group study

Free
Clinical Trials & Observations
Brent L. Wood, Meenakshi Devidas, Ryan J. Summers, Zhiguo Chen, Barbara Asselin, Karen R. Rabin, Patrick A. Zweidler-McKay, Naomi J. Winick, Michael J. Borowitz, William L. Carroll, Elizabeth A. Raetz, Mignon L. Loh, Stephen P. Hunger, Kimberly P. Dunsmore, David T. Teachey, Stuart S. Winter
Journal: Blood
Blood (2023) 142 (24): 2069–2078.
https://doi.org/10.1182/blood.2023020678
Published: 2023
Includes: Supplemental data