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Journal Articles

Real-World Performance of 2022 Revised World Health Organization (WHO) Criteria for Mixed Phenotype Acute Leukemia (MPAL) B/Myeloid Defined Only By Isolated MPO Expression (isoMPO)

Alexandra E. Kovach, Sunil S. Raikar, Jemily Malvar, Matthew J. Oberley, Gerald Wertheim, Karen R. Rabin, Jyotinder N. Punia, Alix Seif, Reuven J. Schore, Dragos C. Luca, Terri L. Guinipero, William G. Woods, Viviane Cahen, Yueh-Yun Chi, Maurice R.G. O'Gorman, Brent L. Wood, Etan Orgel

Blood (2023) 142 (Supplement 1): 1467.

https://doi.org/10.1182/blood-2023-174110

Published: 2023

Journal Articles

Apixaban Is Effective and Safe in Reducing Venous Thromboembolism (VTE) in Obese Patients with Newly Diagnosed Pediatric Acute Lymphoblastic Leukemia/Lymphoblastic Lymphoma (ALL/LL) a Sub-Study Analysis of the Prevapix-ALL/Children's Oncology Group ACCL1333 Trial

Vilmarie Rodriguez, Sarah O'Brien, Glen Lew, Etan Orgel, Kimberly Derr, Mark A. Ranalli, Corinna L. Schultz, Adam J. Esbenshade, Arteid Memaj, Joshua Dyme, Nicholas Favatella, Lesley Mitchell

Blood (2023) 142 (Supplement 1): 810.

https://doi.org/10.1182/blood-2023-180037

Published: 2023

Journal Articles

The International Consensus Classification of acute leukemias of ambiguous lineage

Olga K. Weinberg, Daniel A. Arber, Hartmut Döhner, Charles G. Mullighan, Etan Orgel, Anna Porwit, Richard M. Stone, Michael J. Borowitz

Blood (2023) 141 (18): 2275–2277.

https://doi.org/10.1182/blood.2022019493

Published: 2023

Journal Articles

Standardization in the Diagnosis of Mixed Phenotype Acute Leukemia (MPAL): Semiquantitative, Universally Applicable Flow Cytometric Criteria for Immunophenotypic Lineage Assignment and Isolated MPO

Alexandra E. Kovach, Sunil S. Raikar, Matthew J. Oberley, Gerald Wertheim, Karen R Rabin, Jyotinder N. Punia, Alix E. Seif, Reuven J Schore, Dragos C. Luca, Terri Guinipero, William G Woods, Viviane Cahen, Maurice R.G. O'Gorman, Etan Orgel, Brent L. Wood

Blood (2021) 138 (Supplement 1): 4475.

https://doi.org/10.1182/blood-2021-154295

Published: 2021

Journal Articles

Efficacy and Safety of FLAG-Ida As Frontline Therapy in a Pediatric AML Population: A Single Institution Experience

Andrew Doan, Holly K.T. Huang, Ari J. Hadar, Jemily Malvar, Teresa Rushing, Gordana Raca, Alexandra E. Kovach, Paul Gaynon, Etan Orgel

Blood (2021) 138 (Supplement 1): 2342.

https://doi.org/10.1182/blood-2021-148965

Published: 2021

Journal Articles

Increased prevalence of CRLF2 rearrangements in obesity-associated acute lymphoblastic leukemia

Steven D. Mittelman, Jiyoon Kim, Gordana Raca, Gang Li, Matthew J. Oberley, Etan Orgel

Blood (2021) 138 (2): 199–202.

https://doi.org/10.1182/blood.2021011106

Published: 2021

Includes: Supplemental data

Journal Articles

Preexisting or therapy-induced mutations in relapsed acute lymphoblastic leukemia?

Paul S. Gaynon, Etan Orgel, Lingyun Ji

Blood (2020) 136 (19): 2233–2235.

https://doi.org/10.1182/blood.2020005258

Published: 2020

Journal Articles

Integrin α6 mediates the drug resistance of acute lymphoblastic B-cell leukemia

Blood (2020) 136 (2): 210–223.

https://doi.org/10.1182/blood.2019001417

Published: 2020

Includes: Supplemental data

Journal Articles

Age but Not Adiposity Predicts Asparaginase-Induced Hepatotoxicity during Induction Therapy for Adolescent and Young Adults with Acute Lymphoblastic Leukemia

Etan Orgel, MD MS, Celia Framson, MPH, RD, Rubi Vazquez, PT DPT, David R. Freyer, DO MS, Steven D. Mittelman, MD PhD

Blood (2018) 132 (Supplement 1): 2662.

https://doi.org/10.1182/blood-2018-99-110268

Published: 2018

Journal Articles

Clinical Outcomes in Pediatric Mixed Phenotype Acute Leukemia (MPAL) Differ Depending on Disease Classification Criteria; A Multi-Center Cohort Study

Matthew J. Oberley, MD PhD, Gerald Wertheim, MD, PhD, Sunil S. Raikar, MD, Jemily Malvar, Richard Sposto, PhD, Jyotinder N. Punia, MD, Karen R. Rabin, MD PhD, Alix E. Seif, MD, Reuven J. Schore, MD, Dragos C. Luca, MD, Terri Guinipero, MD, William G. Woods, MD, Maurice R.G. O'Gorman, MD PhD, Etan Orgel, MD MS

Blood (2018) 132 (Supplement 1): 4080.

https://doi.org/10.1182/blood-2018-99-117377

Published: 2018

Journal Articles

L-Carnitine Does Not Reduce Cytotoxicity from Induction Chemotherapy for Acute Lymphoblastic Leukemia

Jessica Sea, PhD, Etan Orgel, MD MS, Steven D. Mittelman, MD PhD

Blood (2018) 132 (Supplement 1): 5156.

https://doi.org/10.1182/blood-2018-99-117921

Published: 2018

Journal Articles

Minimal Residual Disease Risk-Stratification in Pediatric Mixed Phenotype Acute Leukemia: Results of a Multi-Center Cohort Study

Matthew J. Oberley, MD PhD, Sunil S. Raikar, MD, Jemily Malvar, Gerald Wertheim, MD, PhD, Alix E. Seif, MD, Terri Guinipero, MD, Richard Sposto, PhD, Karen R. Rabin, MD PhD, Jyotinder N. Punia, MD, Reuven J. Schore, MD, Dragos C. Luca, MD, William G. Woods, MD, Maurice R.G. O'Gorman, MD PhD, Etan Orgel, MD MS

Blood (2018) 132 (Supplement 1): 558.

https://doi.org/10.1182/blood-2018-99-113606

Published: 2018

Journal Articles

MDS and AML in Shwachman-Diamond Syndrome: Clinical Features and Outcomes

Blood (2017) 130 (Supplement 1): 1177.

https://doi.org/10.1182/blood.V130.Suppl_1.1177.1177

Published: 2017

Journal Articles

Integrin alpha6-Deletion Induces Apoptosis and Src Signaling Changes in Acute Lymphoblastic Leukemia Cells

Eun Ji Gang, MD PhD, Hye Na Kim, Johanna Scott, PhD, Matthew J Oberley, MDPhD, Etan Orgel, MD MS, Steven D. Mittelman, MDPhD, Yao-Te Hsieh, PhD, Markus Muschen, MD, Deepa Bhojwani, MD, Daniel Braas, PhD, Thomas Graeber, PhD, Nora Heisterkamp, PhD, Yong-Mi Kim, MD MPH, PhD

Blood (2017) 130 (Supplement 1): 3878.

https://doi.org/10.1182/blood.V130.Suppl_1.3878.3878

Published: 2017

Journal Articles

Therapy for Children and Adults with EGIL- or WHO2008-Defined Mixed Phenotype Acute Leukemia: A Systematic Review and Meta-Analysis

Maria A Maruffi, MD, Richard Sposto, PhD, Matthew J Oberley, MDPhD, Lynn Kysh, Etan Orgel, MD MS

Blood (2017) 130 (Supplement 1): 2609.

https://doi.org/10.1182/blood.V130.Suppl_1.2609.2609

Published: 2017

Journal Articles

Efficacy of ALL Therapy for WHO2016-Defined Mixed Phenotype Acute Leukemia: A Report from the Children's Oncology Group

Etan Orgel, MD MS, Thomas B. Alexander, MDMPH, Brent Wood, MDPhD, Samir Kahwash, MD, Meenakshi Devidas, Yunfeng Dai, PhD, Todd A Alonzo, PhD, Charles G. Mullighan, MBBS, MD, Hiroto Inaba, MD, Stephen P. Hunger, MD, Alan S Gamis, MD MPH, Andrew J. Carroll, III, PhD, Nyla A. Heerema, PhD, Jason Berman, MD, William G Woods, MD, Mignon L. Loh, MD, Patrick A. Zweidler-McKay, MDPhD, John T Horan, MD

Blood (2017) 130 (Supplement 1): 883.

https://doi.org/10.1182/blood.V130.Suppl_1.883.883

Published: 2017

Journal Articles

Excess Treatment-Related Mortality in Obese Children and Adolescents with Acute Myeloid Leukemia on AAML0531: A Report from the Children's Oncology Group

Lillian Sung, MD PhD FRCPC, Robert Gerbing, BS, Todd A. Alonzo, PhD, Yi-Cheng Wang, MS, Etan Orgel, MD MS, Alan S. Gamis, MD MPH, Richard Aplenc, MD PhD

Blood (2016) 128 (22): 2790.

https://doi.org/10.1182/blood.V128.22.2790.2790

Published: 2016

Journal Articles

Genomic Landscape of Pediatric Mixed Phenotype Acute Leukemia

Thomas B. Alexander, MD MPH, Zhaohui Gu, PhD, John K Choi, MD, Mignon L. Loh, MD, John Horan, MD MPH, Barbara Buldini, MD, Giuseppe Basso, Sarah Elitzur, MD, C. Michel Zwaan, MD PhD, Valerie de Haas, MD PhD, Allen Eng Juh Yeoh, MD, Dirk Reinhardt, MD PhD, Daisuke Tomizawa, MD, PhD, Tim Lammens, Barbara De Moerloose, MD, Li Zhou, PhD, Hiroki Hori, MD PhD, Anthony V. Moorman, PhD, Andrew S. Moore, MBBS FRACP PhD, Ondrej Hrusak, MD PhD, Soheil Meshinchi, MD PhD, Etan Orgel, MD MS, Meenakshi Devidas, PhD, Stephen P. Hunger, MD, Jamie M Guidry Auvil, Malcolm A. Smith, MD PhD, Tanja M. Davidsen, PhD, Leandro C. Hermida, Patee Gesuwan, Marco A. Marra, PhD, Yussanne Ma, PhD, Andrew J. Mungall, Richard Moore, PhD, Daniela S. Gerhard, PhD, Xueyuan Cao, Lei Shi, PhD, Stanley Pounds, PhD, Hiroto Inaba, MD PhD, Charles Mullighan, MBBS, MSc, MD

Blood (2016) 128 (22): 454.

https://doi.org/10.1182/blood.V128.22.454.454

Published: 2016

Journal Articles

Predictive Value of Minimal Residual Disease in WHO2016-Defined Mixed Phenotype Acute Leukemia (MPAL)

Etan Orgel, MD MS, Matthew Oberley, MD PhD, Sisi Li, MD, Jemily Malvar, MS, Maurice O'Gorman, PhD

Blood (2016) 128 (22): 178.

https://doi.org/10.1182/blood.V128.22.178.178

Published: 2016

Journal Articles

Investigating Ethnic Differences in Toxicities of Childhood ALL Therapy

Yasmin Rawlins, BA, Jemily Malvar, MS, Richard Sposto, PhD, Etan Orgel, MD MS, Deepa Bhojwani, MD

Blood (2016) 128 (22): 5989.

https://doi.org/10.1182/blood.V128.22.5989.5989

Published: 2016

NARROW

Real-World Performance of 2022 Revised World Health Organization (WHO) Criteria for Mixed Phenotype Acute Leukemia (MPAL) B/Myeloid Defined Only By Isolated MPO Expression (isoMPO)

Apixaban Is Effective and Safe in Reducing Venous Thromboembolism (VTE) in Obese Patients with Newly Diagnosed Pediatric Acute Lymphoblastic Leukemia/Lymphoblastic Lymphoma (ALL/LL) a Sub-Study Analysis of the Prevapix-ALL/Children's Oncology Group ACCL1333 Trial

The International Consensus Classification of acute leukemias of ambiguous lineage

Standardization in the Diagnosis of Mixed Phenotype Acute Leukemia (MPAL): Semiquantitative, Universally Applicable Flow Cytometric Criteria for Immunophenotypic Lineage Assignment and Isolated MPO

Efficacy and Safety of FLAG-Ida As Frontline Therapy in a Pediatric AML Population: A Single Institution Experience

Increased prevalence of CRLF2 rearrangements in obesity-associated acute lymphoblastic leukemia

Preexisting or therapy-induced mutations in relapsed acute lymphoblastic leukemia?

Integrin α6 mediates the drug resistance of acute lymphoblastic B-cell leukemia

Age but Not Adiposity Predicts Asparaginase-Induced Hepatotoxicity during Induction Therapy for Adolescent and Young Adults with Acute Lymphoblastic Leukemia

Clinical Outcomes in Pediatric Mixed Phenotype Acute Leukemia (MPAL) Differ Depending on Disease Classification Criteria; A Multi-Center Cohort Study

L-Carnitine Does Not Reduce Cytotoxicity from Induction Chemotherapy for Acute Lymphoblastic Leukemia

Minimal Residual Disease Risk-Stratification in Pediatric Mixed Phenotype Acute Leukemia: Results of a Multi-Center Cohort Study

MDS and AML in Shwachman-Diamond Syndrome: Clinical Features and Outcomes

Integrin alpha6-Deletion Induces Apoptosis and Src Signaling Changes in Acute Lymphoblastic Leukemia Cells

Therapy for Children and Adults with EGIL- or WHO2008-Defined Mixed Phenotype Acute Leukemia: A Systematic Review and Meta-Analysis

Efficacy of ALL Therapy for WHO2016-Defined Mixed Phenotype Acute Leukemia: A Report from the Children's Oncology Group

Excess Treatment-Related Mortality in Obese Children and Adolescents with Acute Myeloid Leukemia on AAML0531: A Report from the Children's Oncology Group

Genomic Landscape of Pediatric Mixed Phenotype Acute Leukemia

Predictive Value of Minimal Residual Disease in WHO2016-Defined Mixed Phenotype Acute Leukemia (MPAL)

Investigating Ethnic Differences in Toxicities of Childhood ALL Therapy

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American Society of Hematology

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