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Karen R Rabin
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Journal Articles

Prognostic significance of ETP phenotype and minimal residual disease in T-ALL: a Children’s Oncology Group study

Clinical Trials & Observations
Brent L. Wood, Meenakshi Devidas, Ryan J. Summers, Zhiguo Chen, Barbara Asselin, Karen R. Rabin, Patrick A. Zweidler-McKay, Naomi J. Winick, Michael J. Borowitz, William L. Carroll, Elizabeth A. Raetz, Mignon L. Loh, Stephen P. Hunger, Kimberly P. Dunsmore, David T. Teachey, Stuart S. Winter
Journal: Blood
Blood (2023) 142 (24): 2069–2078.
https://doi.org/10.1182/blood.2023020678
Published: 2023
Includes: Supplemental data
Journal Articles

A Novel Transgenic Mouse Model of Down Syndrome Acute Lymphoblastic Leukemia Identifies Targetable Vulnerabilities

Jacob J. Junco, Raushan Rashid, Maci Terrell, Michelle Alozie, Max Rochette, Barry Zorman, Pavel Sumazin, Lauren Rowland, Gino Dettorre, Reid T. Powell, Clifford C. Stephan, Peter J. Davies, Margie M. Moczygemba, Jun J. Yang, Karen R. Rabin
Journal: Blood
Blood (2023) 142 (Supplement 1): 2981.
https://doi.org/10.1182/blood-2023-187324
Published: 2023
Journal Articles

Feasibility and Outcome of Post-Induction Therapy Incorporating Dasatinib for Patients with Newly Diagnosed ABL-Class Fusion B-Lymphoblastic Leukemia (ABL-class Fusion B-ALL): Children's Oncology Group AALL1131

Wanda L. Salzer, Michael J. Burke, Meenakshi Devidas, Zhiguo (Bruce) Chen, Michael J. Borowitz, Andrew J Carroll, I-Ming L. Chen, Julie M. Gastier-Foster, Richard C. Harvey, Nyla A. Heerema, Charles G. Mullighan, Karen R. Rabin, Shalini C Reshmi, Cheryl L. Willman, Brent L. Wood, Naomi J. Winick, William L. Carroll, Elizabeth A. Raetz, Mignon L. Loh, Stephen P. Hunger
Journal: Blood
Blood (2023) 142 (Supplement 1): 961.
https://doi.org/10.1182/blood-2023-190495
Published: 2023
Journal Articles

Real-World Performance of 2022 Revised World Health Organization (WHO) Criteria for Mixed Phenotype Acute Leukemia (MPAL) B/Myeloid Defined Only By Isolated MPO Expression (isoMPO)

Alexandra E. Kovach, Sunil S. Raikar, Jemily Malvar, Matthew J. Oberley, Gerald Wertheim, Karen R. Rabin, Jyotinder N. Punia, Alix Seif, Reuven J. Schore, Dragos C. Luca, Terri L. Guinipero, William G. Woods, Viviane Cahen, Yueh-Yun Chi, Maurice R.G. O'Gorman, Brent L. Wood, Etan Orgel
Journal: Blood
Blood (2023) 142 (Supplement 1): 1467.
https://doi.org/10.1182/blood-2023-174110
Published: 2023
Journal Articles

Patients with Down Syndrome and High-Risk B-Acute Lymphoblastic Leukemia Demonstrate Improved Outcomes on a Modified Chemotherapy Regimen: A Report from Children's Oncology Group Study AALL1131

Vilmarie Rodriguez, Meenakshi Devidas, Zhiguo (Bruce) Chen, Andrew J Carroll, Nyla A. Heerema, Michael J. Borowitz, Brent L. Wood, William L. Carroll, Naomi J Winick, Elizabeth A. Raetz, Mignon L. Loh, Michael J. Burke, Wanda L. Salzer, Stephen P. Hunger, Karen R. Rabin
Journal: Blood
Blood (2023) 142 (Supplement 1): 824.
https://doi.org/10.1182/blood-2023-185368
Published: 2023
Journal Articles

Association of Latino Ethnicity with Cytogenetic Subtypes in Pediatric Acute Myeloid Leukemia

Kevin Wells Tien, Jennifer M. Geris, Chi-Fan Lin, Charles Cook, Olga Taylor, Maria Isabel Castellanos, Van Thu Huynh, Kathleen Ludwig, Laura J. Klesse, Sandi Pruitt, Amy Hughes, Kenneth Matthew Heym, Timothy Griffin, Rodrigo Erana, Juan C. Bernini, Karen R. Rabin, Michael E. Scheurer, Philip J. Lupo, Maria Monica Gramatges
Journal: Blood
Blood (2023) 142 (Supplement 1): 4313.
https://doi.org/10.1182/blood-2023-186968
Published: 2023
Journal Articles

Risk-Adjusted Therapies Yield Equivalent Outcomes for Adolescents and Young Adults (AYAs) Treated for Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia (T-ALL) on Children's Oncology Group (COG) Studies AALL0434 and AALL1231

Susan I. Colace, Meenakshi Devidas, Zhiguo (Bruce) Chen, Robert J. Hayashi, Brent L. Wood, Natia Esiashvili, Samir Patel, Andrew J Carroll, Nyla A. Heerema, Barbara Asselin, Karen R. Rabin, Patrick A. Zweidler-McKay, Elizabeth A. Raetz, Mignon L. Loh, Naomi J. Winick, William L. Carroll, David T. Teachey, Stuart S. Winter, Kimberly P. Dunsmore
Journal: Blood
Blood (2023) 142 (Supplement 1): 517.
https://doi.org/10.1182/blood-2023-190141
Published: 2023
Journal Articles

Development of a Novel Methotrexate-Related Neurotoxicity Risk Score in Pediatric Acute Leukemia: A Report from the Reducing Ethnic Disparities in Acute Leukemia (REDIAL) Consortium

Rachel Harris, Olga Taylor, Melanie Brooke Bernhardt, Ashley Chavana, Mark Zobeck, Philip J. Lupo, Karen R. Rabin, Michael E. Scheurer, Austin L Brown
Journal: Blood
Blood (2023) 142 (Supplement 1): 2828.
https://doi.org/10.1182/blood-2023-189986
Published: 2023
Journal Articles

Heritable Variation in Lymphocyte-Related Traits and Risk of Down Syndrome Acute Lymphoblastic Leukemia: A Mendelian Randomization Study

Yunqi Li, Melissa A. Richard, Linda Kachuri, Yao Yu, Ching-Ju Ruu Hsu, Tracie C. Rosser, Elizabeth J. Leslie, Meenakshi Devidas, Elizabeth A. Raetz, Mignon L. Loh, Stephen P. Hunger, Neetha Paul Eduthan, Matthew D. Galbraith, Joaquin Espinosa, Jun J. Yang, Stephanie L. Sherman, Chad D. Huff, Karen R. Rabin, Philip J. Lupo, Adam J. de Smith
Journal: Blood
Blood (2023) 142 (Supplement 1): 4198.
https://doi.org/10.1182/blood-2023-188434
Published: 2023
Journal Articles

Association of Latino Ethnicity with Cytogenetic Subtype in Pediatric Acute Lymphoblastic Leukemia: A Report from the Reducing Ethnic Disparities in Acute Leukemia Consortium

Maria D. Leon-Camarena, Jennifer M. Geris, Maria Isabel Castellanos, Olga Taylor, Veronica Garcia-Morales, Austin L Brown, Pagna Sok, Van Thu Huynh, Kathleen Ludwig, Laura J. Klesse, Sandi Pruitt, Amy Hughes, Kevin Wells Tien, Kenneth Matthew Heym, Timothy Griffin, Rodrigo Erana, Juan C. Bernini, Philip J. Lupo, M. Monica Gramatges, Michael E. Scheurer, Karen R. Rabin
Journal: Blood
Blood (2023) 142 (Supplement 1): 4206.
https://doi.org/10.1182/blood-2023-188022
Published: 2023
Journal Articles

Insights into the genomics of iAMP21-ALL

Karen R. Rabin
Journal: Blood
Blood (2023) 142 (8): 682–684.
https://doi.org/10.1182/blood.2023021020
Published: 2023
Journal Articles

Genomic landscape of Down syndrome–associated acute lymphoblastic leukemia

Zhenhua Li, Ti-Cheng Chang, Jacob J. Junco, Meenakshi Devidas, Yizhen Li, Wenjian Yang, Xin Huang, Dale J. Hedges, Zhongshan Cheng, Mary Shago, Andrew J. Carroll, Nyla A. Heerema, Julie Gastier-Foster, Brent L. Wood, Michael J. Borowitz, Lauren Sanclemente, Elizabeth A. Raetz, Stephen P. Hunger, Eleanor Feingold, Tracie C. Rosser, Stephanie L. Sherman, Mignon L. Loh, Charles G. Mullighan, Jiyang Yu, Gang Wu, Philip J. Lupo, Karen R. Rabin, Jun J. Yang
Journal: Blood
Blood (2023) 142 (2): 172–184.
https://doi.org/10.1182/blood.2023019765
Published: 2023
Includes: Supplemental data
Journal Articles

Central nervous system status is prognostic in T-cell acute lymphoblastic leukemia: a Children’s Oncology Group report

Clinical Trials & Observations
Nathan P. Gossai, Meenakshi Devidas, Zhiguo Chen, Brent L. Wood, Patrick A. Zweidler-McKay, Karen R. Rabin, Mignon L. Loh, Elizabeth A. Raetz, Naomi J. Winick, Michael J. Burke, Andrew J. Carroll, Natia Esiashvili, Nyla A. Heerema, William L. Carroll, Stephen P. Hunger, Kimberly P. Dunsmore, Stuart S. Winter, David T. Teachey
Journal: Blood
Blood (2023) 141 (15): 1802–1811.
https://doi.org/10.1182/blood.2022018653
Published: 2023
Includes: Supplemental data
Journal Articles

Standardization in the Diagnosis of Mixed Phenotype Acute Leukemia (MPAL): Semiquantitative, Universally Applicable Flow Cytometric Criteria for Immunophenotypic Lineage Assignment and Isolated MPO

Alexandra E. Kovach, Sunil S. Raikar, Matthew J. Oberley, Gerald Wertheim, Karen R Rabin, Jyotinder N. Punia, Alix E. Seif, Reuven J Schore, Dragos C. Luca, Terri Guinipero, William G Woods, Viviane Cahen, Maurice R.G. O'Gorman, Etan Orgel, Brent L. Wood
Journal: Blood
Blood (2021) 138 (Supplement 1): 4475.
https://doi.org/10.1182/blood-2021-154295
Published: 2021
Journal Articles

Comparison of Current and Enhanced Risk Stratification of 21,199 Children, Adolescents, and Young Adults with Acute Lymphoblastic Leukemia Using Objective Risk Categorization Criteria: A Children's Oncology Group Report

Natalie Delrocco, Mignon L. Loh, Michael Borowitz, Karen R Rabin, Patrick A Zweidler-McKay, Kelly W Maloney, Leonard A. Mattano, Eric C Larsen, Anne L Angiolillo, Reuven J Schore, Michael J. Burke, Wanda L Salzer, Brent L. Wood, Andrew J Carroll, Nyla A. Heerema, Shalini C Reshmi, Julie M Gastier-Foster, Richard C Harvey, I-Ming L Chen, Kathryn G Roberts, Charles G. Mullighan, Cheryl L Willman, Naomi J Winick, William L. Carroll, Stephen P. Hunger, Elizabeth A. Raetz, Meenakshi Devidas, John Kairalla
Journal: Blood
Blood (2021) 138 (Supplement 1): 2382.
https://doi.org/10.1182/blood-2021-148593
Published: 2021
Journal Articles

Non-Classical Monocyte Abundance Is an Independent Adverse Risk Factor for Relapse in Pediatric B-ALL

Gloria Paz Contreras Yametti, Nikki Ann Evensen, Meenakshi Devidas, Elizabeth A. Raetz, Karen R Rabin, David T. Teachey, Iannis Aifantis, William L. Carroll, Matthew Witkowski
Journal: Blood
Blood (2021) 138 (Supplement 1): 1316.
https://doi.org/10.1182/blood-2021-146918
Published: 2021
Journal Articles

Blinatumomab Associated Seizure Risk in Patients with Down Syndrome and B-Lymphoblastic Leukemia: An Interim Report from Children's Oncology Group (COG) Study AALL1731

Amanda M. Li, Karen R Rabin, John Kairalla, Cindy Wang, Meenakshi Devidas, Olga Militano, Maki Okada, Johann K Hitzler, Anne L Angiolillo, Elizabeth A. Raetz, Mignon L. Loh, Sumit Gupta, Rachel E. Rau
Journal: Blood
Blood (2021) 138 (Supplement 1): 2304.
https://doi.org/10.1182/blood-2021-148967
Published: 2021
Journal Articles

Epigenome-Wide Association Study of Acute Lymphoblastic Leukemia in Children with Down Syndrome

Shaobo Li, Pagna Sok, Keren Xu, Ivo S Muskens, Natalina Elliott, Swe Swe Myint, Priyatama Pandey, Helen M Hansen, Libby M Morimoto, Alice Y Kang, Catherine Metayer, Xiaomei Ma, Beth A Mueller, Anindita Roy, Irene Roberts, Karen R Rabin, Austin L Brown, Philip J. Lupo, Joseph L. Wiemels, Adam J. de Smith
Journal: Blood
Blood (2021) 138 (Supplement 1): 214.
https://doi.org/10.1182/blood-2021-151454
Published: 2021
Journal Articles

Racial, Ethnic, and Socioeconomic Factors Result in Disparities in Outcome Among Children with Acute Lymphoblastic Leukemia Not Fully Attenuated By Disease Prognosticators: A Children's Oncology Group (COG) Study

Sumit Gupta, David T. Teachey, Meenakshi Devidas, Yunfeng Dai, Richard Aplenc, Lena Winestone, Kira O Bona, Karen R Rabin, Patrick A Zweidler-McKay, Kelly W Maloney, Leonard A. Mattano, Eric C Larsen, Anne L Angiolillo, Reuven J Schore, Michael J. Burke, Wanda L Salzer, Stuart S. Winter, Kimberly P. Dunsmore, Naomi J Winick, William L. Carroll, Stephen P Hunger, Mignon L. Loh
Journal: Blood
Blood (2021) 138 (Supplement 1): 211.
https://doi.org/10.1182/blood-2021-147386
Published: 2021
Journal Articles

Molecular basis of ETV6 -mediated predisposition to childhood acute lymphoblastic leukemia

Rina Nishii, Rebekah Baskin-Doerfler, Wentao Yang, Ninad Oak, Xujie Zhao, Wenjian Yang, Keito Hoshitsuki, Mackenzie Bloom, Katherine Verbist, Melissa Burns, Zhenhua Li, Ting-Nien Lin, Maoxiang Qian, Takaya Moriyama, Julie M. Gastier-Foster, Karen R. Rabin, Elizabeth Raetz, Charles Mullighan, Ching-Hon Pui, Allen Eng-Juh Yeoh, Jinghui Zhang, Monika L. Metzger, Jeffery M. Klco, Stephen P. Hunger, Scott Newman, Gang Wu, Mignon L. Loh, Kim E. Nichols, Jun J. Yang
Journal: Blood
Blood (2021) 137 (3): 364–373.
https://doi.org/10.1182/blood.2020006164
Published: 2021
Includes: Supplemental data