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Jacob J. Junco
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Journal Articles

A Novel Transgenic Mouse Model of Down Syndrome Acute Lymphoblastic Leukemia Identifies Targetable Vulnerabilities

Jacob J. Junco, Raushan Rashid, Maci Terrell, Michelle Alozie, Max Rochette, Barry Zorman, Pavel Sumazin, Lauren Rowland, Gino Dettorre, Reid T. Powell, Clifford C. Stephan, Peter J. Davies, Margie M. Moczygemba, Jun J. Yang, Karen R. Rabin
Journal: Blood
Blood (2023) 142 (Supplement 1): 2981.
https://doi.org/10.1182/blood-2023-187324
Published: 2023
Journal Articles

Genomic landscape of Down syndrome–associated acute lymphoblastic leukemia

Zhenhua Li, Ti-Cheng Chang, Jacob J. Junco, Meenakshi Devidas, Yizhen Li, Wenjian Yang, Xin Huang, Dale J. Hedges, Zhongshan Cheng, Mary Shago, Andrew J. Carroll, Nyla A. Heerema, Julie Gastier-Foster, Brent L. Wood, Michael J. Borowitz, Lauren Sanclemente, Elizabeth A. Raetz, Stephen P. Hunger, Eleanor Feingold, Tracie C. Rosser, Stephanie L. Sherman, Mignon L. Loh, Charles G. Mullighan, Jiyang Yu, Gang Wu, Philip J. Lupo, Karen R. Rabin, Jun J. Yang
Journal: Blood
Blood (2023) 142 (2): 172–184.
https://doi.org/10.1182/blood.2023019765
Published: 2023
Includes: Supplemental data
Journal Articles

Pharmacological Inhibition of MAP2K7 Induces Apoptosis and Cell Cycle Arrest in T-Cell Acute Lymphoblastic Leukemia

Taylor J Chen, BS, Ye Shen, PhD, Cory Seth Bridges, BS, Chun Shik Park, PhD, Jacob J. Junco, PhD, Karen R. Rabin, MD PhD, H. Daniel Lacorazza, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3889.
https://doi.org/10.1182/blood-2019-129127
Published: 2019
Journal Articles

A Novel Short Latency, High Penetrance Model of KRAS Mutation-Driven T-Cell Acute Lymphoblastic Leukemia

Jacob J. Junco, PhD, Vincent Ulysses Gant, PhD, Maci S. Terrell, BS, Matthew Benjamin Miller, MD, Chun Shik Park, PhD, Taylor J Chen, BS, H. Daniel Lacorazza, PhD, Margaret Goodell, PhD, Rachel E. Rau, MD, Karen R. Rabin, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3792.
https://doi.org/10.1182/blood-2019-126858
Published: 2019
Journal Articles

CRLF2 Overexpression Demonstrates Enhanced Leukemogenicity in Down Syndrome Hematopoietic Cells

Jacob J. Junco, PhD BS, Shan Liang, BS, Vishal Gokani, B.S., Vincent Ulysses Gant, PhD BS, Jaime Munoz, B.S., Allison Mayle, PhD, Chun Shik Park, PhD, H. Daniel Lacorazza, PhD, Margaret A Goodell, PhD, Karen R. Rabin, MD PhD
Journal: Blood
Blood (2016) 128 (22): 2708.
https://doi.org/10.1182/blood.V128.22.2708.2708
Published: 2016
Journal Articles

Integrated Genomic Analysis of Down Syndrome Acute Lymphoblastic Leukemia Reveals Recurrent Cancer Gene Alterations and Evidence of Frequent Subclonal Driver Events

Oliver A, Hampton, PhD, Enrique I. Ramos, PhD, Nipun Kakkar, B.S., Jacob J. Junco, PhD BS, Jacquelyn Reuther, PhD, Anne Angiolillo, MD, Reuven J Schore, MD, Michael J. Burke, MD, Wanda Salzer, MD, Meenakshi Devidas, PhD, Andrew J. Carroll, PhD, Nyla A. Heerema, PhD, Kelly Maloney, MD, Naomi Winick, MD, William L. Carroll, MD, Elizabeth Raetz, MD, Mignon L. Loh, MD, Stephen P. Hunger, MD, Juhi Jain, MD, Harsha Doddapaneni, PhD, Donna M. Muzny, M.S., David A. Wheeler, PhD, Kevin E. Fisher, MD PhD, Dolores H. Lopez-Terrada, MD PhD, Angshumoy Roy, MD PhD, Donald Williams Parsons, MD PhD, Karen R. Rabin, MD PhD
Journal: Blood
Blood (2016) 128 (22): 4083.
https://doi.org/10.1182/blood.V128.22.4083.4083
Published: 2016