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Nyla Heerema
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Journal Articles

Outcomes in children with NCI standard-risk b-acute lymphoblastic leukemia treated with intensified post-induction therapy: Results from Children's Oncology Group studies AALL0932 and AALL1131

Free
Ruth Wang'ondu, Anne Angiolillo, Meenakshi Devidas, Karen Rabin, Michael Borowitz, Brent Wood, Andrew Carroll, Nyla Heerema, Emily Hibbitts, Reuven Schore, William Carroll, Michael Burke, Wanda Salzer, Lia Gore, Naomi Winick, David Teachey, Elizabeth Raetz, Mignon Loh, Stephen Hunger, John Kairalla
Journal: Blood
Blood (2025) 146 (Supplement 1): 757.
https://doi.org/10.1182/blood-2025-757
Published: 2025
Journal Articles

Factors associated with central nervous system relapse after b-acute lymphoblastic leukemia: A Children's oncology group report

Free
Aman Wadhwa, Lingyun Ji, Alice Dang, Xinxin Xu, Meenakshi Devidas, John Kairalla, Mary Shago, Nyla Heerema, Andrew Carroll, Michael Borowitz, Brent Wood, Eric Larsen, Kelly Maloney, Reuven Schore, Wanda Salzer, Michael Burke, Stephen Hunger, David Teachey, Naomi Winick, Elizabeth Raetz, Mignon Loh, Deepa Bhojwani, Sumit Gupta
Journal: Blood
Blood (2025) 146 (Supplement 1): 762.
https://doi.org/10.1182/blood-2025-762
Published: 2025
Journal Articles

RAS mutations negate the favorable impact of NPM1 in older patients with newly diagnosed Acute Myeloid Leukemia treated with ven/HMA

Free
Fieke Hoff, Alexander Li, Ying Huang, Rina Welkie, Ronan Swords, Elie Traer, Eytan Stein, Tara Lin, Maria Baer, Vu Duong, William Blum, Martha Arellano, Wendy Stock, Olatoyosi Odenike, Joshua Zeidner, Rebecca Olin, Catherine Smith, Gary Schiller, Emily Curran, Shivani Handa, Nyla Heerema, Timothy Chen, Molly Martycz, Mona Stefanos, Sonja Marcus, Leonard Rosenberg, Brian Druker, Ross Levine, Ashley Yocum, Uma Borate, Alice Mims, John Byrd, Yazan Madanat
Journal: Blood
Blood (2025) 146 (Supplement 1): 995.
https://doi.org/10.1182/blood-2025-995
Published: 2025
Journal Articles

Outcomes after relapse for adolescent and young adult patients with ALL: Results from the Children's oncology group

Free
Jordyn Griffin, Lingyun Ji, Alice Dang, Xinxin Xu, Loretta Li, Naomi Winick, William Carroll, Stephen Hunger, Elizabeth Raetz, Mignon Loh, Michael Borowitz, Brent Wood, Mary Shago, Nyla Heerema, Andrew Carroll, Jennifer McNeer, Deepa Bhojwani, Susan Rheingold
Journal: Blood
Blood (2025) 146 (Supplement 1): 548.
https://doi.org/10.1182/blood-2025-548
Published: 2025
Journal Articles

The genomic landscape of acute lymphoblastic leukemia with intrachromosomal amplification of chromosome 21

Free
Qingsong Gao, Sarra L. Ryan, Ilaria Iacobucci, Pankaj S. Ghate, Ruth E. Cranston, Claire Schwab, Abdelrahman H. Elsayed, Lei Shi, Stanley Pounds, Shaohua Lei, Pradyuamna Baviskar, Deqing Pei, Cheng Cheng, Matthew Bashton, Paul Sinclair, David R. Bentley, Mark T. Ross, Zoya Kingsbury, Terena James, Kathryn G. Roberts, Meenakshi Devidas, Yiping Fan, Wenan Chen, Ti-Cheng Chang, Gang Wu, Andrew Carroll, Nyla Heerema, Virginia Valentine, Marcus Valentine, Wenjian Yang, Jun J. Yang, Anthony V. Moorman, Christine J. Harrison, Charles G. Mullighan
Journal: Blood
Blood (2023) 142 (8): 711–723.
https://doi.org/10.1182/blood.2022019094
Published: 2023
Includes: Supplemental data
Journal Articles

Phase 1/2 study of lumiliximab combined with fludarabine, cyclophosphamide, and rituximab in patients with relapsed or refractory chronic lymphocytic leukemia

Free
Clinical Trials & Observations
John C. Byrd, Thomas J. Kipps, Ian W. Flinn, Januaro Castro, Thomas S. Lin, William Wierda, Nyla Heerema, James Woodworth, Steve Hughes, Shabnam Tangri, Sarah Harris, Dee Wynne, Arturo Molina, Bryan Leigh, Susan O'Brien
Journal: Blood
Blood (2010) 115 (3): 489–495.
https://doi.org/10.1182/blood-2009-08-237727
Published: 2010
Journal Articles

del(17p13.1) in Chronic Lymphocytic Leukemia Confers Poor Prognosis Even at Low Percentage Involvement and Increases Proportionately with Increase in Clonal Involvement.

Free
Leslie A. Andritsos, MD, Jeffrey Jones, M.D., Gerard Lozanski, M.D., Thomas S. Lin, M.D., Kristie A. Blum, M.D., Michael R. Grever, M.D., David Jarjoura, Ph.D., John C. Byrd, M.D., Nyla Heerema, M.D.
Journal: Blood
Blood (2007) 110 (11): 2073.
https://doi.org/10.1182/blood.V110.11.2073.2073
Published: 2007
Journal Articles

Prevalence and Prognostic Significance of c-KIT Mutations in Pediatric CBF AML Patients Enrolled on Serial CCG/COG Protocols.

Free
Jessica Pollard, Todd Alonzo, Robert Gerbing, Rong Zeng, Betsy Hirsch, Susana Raimondi, Nyla Heerema, William Woods, Beverly Lange, Craig Hurwitz, Robert Arceci, Jerald Radich, Irwin Bernstein, Michael Heinrich, Soheil Meshinchi
Journal: Blood
Blood (2007) 110 (11): 1442.
https://doi.org/10.1182/blood.V110.11.1442.1442
Published: 2007
Journal Articles

Combination Chemoimmunotherapy with Pentostatin, Cyclophosphamide and Rituximab Shows Significant Clinical Activity with Low Accompanying Toxicity in Previously Untreated B-Chronic Lymphocytic Leukemia.

Free
Neil Kay, MD, Susan Geyer, PhD, Timothy Call, MD, Tait Shanafelt, MD, Clive Zent, MD, Diane Jelinek, PhD, Renee Tschumper, Nancy Bone, Gordon Dewald, PhD, Thomas Lin, PhD, Nyla Heerema, PhD, Laura Smith, Michael Grever, MD, John Byrd, MD
Journal: Blood
Blood (2006) 108 (11): 35.
https://doi.org/10.1182/blood.V108.11.35.35
Published: 2006
Journal Articles

A Novel Celecoxib Derivative, OSU03012, Induces Cytotoxicity in Primary CLL Cells and Transformed B-Cell Lymphoma Via a Caspase and Bcl-2 Independent Mechanism.

Free
Amy Johnson, PhD, Lisa Smith, Jiuxiang Zhu, Nyla Heerema, PhD, Sara Guster, Andrew Mone, MD, PhD, Michael Grever, MD, Ching-Shih Chen, PhD, John Byrd, MD
Journal: Blood
Blood (2004) 104 (11): 3471.
https://doi.org/10.1182/blood.V104.11.3471.3471
Published: 2004
Journal Articles

Clinical Significance of MLL-AF4 Fusion Transcript Expression in the Absence of a Cytogenetically Detectable t(4;11)(q21;q23) Chromosomal Translocation

Free
Fatih M. Uckun, Kim Herman-Hatten, Mya-Lisa Crotty, Martha G. Sensel, Harland N. Sather, Lisa Tuel-Ahlgren, Mireille B. Sarquis, Bruce Bostrom, James B. Nachman, Peter G. Steinherz, Paul S. Gaynon, Nyla Heerema
Journal: Blood
Blood (1998) 92 (3): 810–821.
https://doi.org/10.1182/blood.V92.3.810
Published: 1998