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William Blum
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Journal Articles

Beat AML S8 Group 2: Gilteritinib (GILT) in Combination with Decitabine (DEC) and Venetoclax (VEN) in Untreated FLT3 Mutated Acute Myeloid Leukemia (AML) Patients Age ≥60 with High and Low Variant Allele Frequency (VAF)

Qiuying (Selina) Liu, Rina Li Welkie, Ying Huang, Ronan T. Swords, Tara L Lin, Kristin L Koenig, Yazan F. Madanat, Prapti A. Patel, Robert H. Collins, William Blum, Martha Arellano, Maria R. Baer, Wendy Stock, Tibor J. Kovacsovics, Rebecca Olin, Emily K Curran, Eytan M. Stein, Gary J. Schiller, Joshua F. Zeidner, Robert L. Redner, Nyla A. Heerema, Molly Martycz, Leonard Rosenberg, Sonja Gullen Marcus, Timothy Chen, Mona Stefanos, Ross L Levine, Brian J. Druker, Ashley Owen Yocum, Amy Burd, Alice Mims, Uma M. Borate, John C. Byrd, Elie Traer
Journal: Blood
Blood (2023) 142 (Supplement 1): 5933.
https://doi.org/10.1182/blood-2023-179609
Published: 2023
Journal Articles

Wilms' Tumor 1 Functions As a Tumor Suppressor to Suppress FLT3-STAT Signaling and Epigenetic Remodeling in Acute Myeloid Leukemia (CALGB 8461, 9665 and 20202; Alliance)

Daelynn Buelow, Xining Yang, Deedra Nicolet, Krzysztof Mrózek, Kathrin Krowiorz, Raj Bhayadia, Jack Stromatt, Anna Denny, Christoph Wiegel, Colin Corbett, Salma Abdelbaky, Yonger Xue, Yizhou Dong, Jeremy Hui, Arshia Shad, Sharon Gao, Si Wei Wu, Marion van den Bosch, Liam MacPhee, Leo Escano, James S. Blachly, Jonathan E Kolitz, William Blum, Maria R. Baer, Jan-Henning Klusmann, Ann-Kathrin Eisfeld, Arefeh Rouhi, Sharyn D. Baker, Florian Kuchenbauer, Christopher C. Oakes
Journal: Blood
Blood (2023) 142 (Supplement 1): 4126.
https://doi.org/10.1182/blood-2023-188892
Published: 2023
Journal Articles

Factors Impacting Response to Olutasidenib in Patients with mIDH1 Acute Myeloid Leukemia

Eunice S. Wang, Brian A. Jonas, Justin M. Watts, Joseph Jurcic, P. Brent Ferrell, Jr., Shira N. Dinner, Jay Yang, Karen Seiter, Alice Mims, William B. Donnellan, William Blum, Jorge Cortes
Journal: Blood
Blood (2023) 142 (Supplement 1): 6047.
https://doi.org/10.1182/blood-2023-187584
Published: 2023
Journal Articles

Ubtf- Tandem Duplications Are Recurrent Somatic Genetic Events in Adult AML and Associate with Additional Structural Variants and a Distinct Gene Expression Profile (Alliance)

Emily K Curran, Deedra Nicolet, Alejandro Otero-Bravo, Krzysztof Mrózek, Ben Kelly, Christopher J. Walker, Jill Buss, Andrea Laganson, Yazan Abu-Shihab, Alice Mims, William Blum, Jonathan E Kolitz, Bayard L Powell, Geoffrey L Uy, Wendy Stock, Richard M Stone, Andrew J Carroll, John C. Byrd, Elaine R Mardis, Ann-Kathrin Eisfeld
Journal: Blood
Blood (2023) 142 (Supplement 1): 4312.
https://doi.org/10.1182/blood-2023-186722
Published: 2023
Journal Articles

Olutasidenib for the Treatment of mIDH1 Acute Myeloid Leukemia in Patients Relapsed or Refractory to Hematopoietic Stem Cell Transplant, Prior mIDH1 Inhibitor, or Venetoclax

Jorge Cortes, Joseph Jurcic, Maria R. Baer, William Blum, P. Brent Ferrell, Jr., Brian A. Jonas, Sangmin Lee, Alice Mims, Shyam Ajay Patel, Gary J. Schiller, Jay Yang, Justin M. Watts
Journal: Blood
Blood (2023) 142 (Supplement 1): 2888.
https://doi.org/10.1182/blood-2023-187861
Published: 2023
Journal Articles

Genomic Characterization of Newly Diagnosed Acute Myeloid Leukemia in Patients Age 60 Years and Older; A Report from the Beat AML Master Trial

Fieke W Hoff, Ying Huang, Rina Li Welkie, Ronan T. Swords, Elie Traer, Eytan M. Stein, Tara L Lin, Prapti A. Patel, Robert H. Collins, Maria R. Baer, Vu H. Duong, William Blum, Martha Arellano, Wendy Stock, Olatoyosi Odenike, Robert L. Redner, Tibor J. Kovacsovics, Michael W. Deininger, Joshua F. Zeidner, Rebecca Olin, Catherine C. Smith, James M. Foran, Gary J. Schiller, Emily K Curran, Kristin L Koenig, Nyla A. Heerema, Timothy Chen, Molly Martycz, Mona Stefanos, Sonja Gullen Marcus, Leonard Rosenberg, Brian J. Druker, Ross L Levine, Amy Burd, Ashley Owen Yocum, Uma M. Borate, Alice Mims, John C. Byrd, Yazan F. Madanat
Journal: Blood
Blood (2023) 142 (Supplement 1): 4296.
https://doi.org/10.1182/blood-2023-187044
Published: 2023
Journal Articles

A Randomized Phase 2 Trial of 28-Day (Arm A) Versus 14-Day (Arm B) Schedule of Venetoclax + Azacitidine in Newly Diagnosed Acute Myeloid Leukemia Patients ≥ 60 Years

Uma M. Borate, Ying Huang, Mary F. Johnson, Joshua F. Zeidner, Ronan T. Swords, Kristin L Koenig, Eytan M. Stein, Maria R. Baer, Wendy Stock, Yazan F. Madanat, Rebecca Olin, William Blum, Gary J. Schiller, Tara L Lin, Robert L. Redner, Emily K Curran, Nyla A. Heerema, Molly Martycz, Leonard Rosenberg, Sonja Gullen Marcus, Timothy Chen, Mona Stefanos, Ross L Levine, Brian J. Druker, Ashley Owen Yocum, Amy Burd, Alice Mims, John C. Byrd
Journal: Blood
Blood (2023) 142 (Supplement 1): 1535.
https://doi.org/10.1182/blood-2023-187383
Published: 2023
Journal Articles

BRAF -Mutated Acute Myeloid Leukemia (AML) Represents a Distinct, Prognostically Poor Subgroup Enriched in Myelodysplasia-Related (MR-)AML

Yazan Abu-Shihab, Deedra Nicolet, Krzysztof Mrózek, Mark Routbort, Keyur P. Patel, Christopher J. Walker, Jill Buss, Andrew Stiff, Andrea Laganson, Courtney D. DiNardo, Naval Daver, Tapan M. Kadia, Gautam Borthakur, Farhad Ravandi, Andrew J Carroll, Jonathan E Kolitz, Bayard L Powell, William Blum, Maria R. Baer, Guido Marcucci, Geoffrey L Uy, Wendy Stock, Richard M Stone, L. Jeffrey Medeiros, Robert L. Bowman, John C. Byrd, James S. Blachly, Linde A. Miles, Ann-Kathrin Eisfeld, Sanam Loghavi
Journal: Blood
Blood (2023) 142 (Supplement 1): 1575.
https://doi.org/10.1182/blood-2023-185135
Published: 2023
Journal Articles

Impact of Cytarabine Pharmacogenomics on Survival of Adolescent and Young Adults with AML and Its Clinical Relevance in Black Patients

Richard J Marrero, Deedra Nicolet, Vivek M. Shastri, Krzysztof Mrózek, Christopher J. Walker, William Blum, Bayard L Powell, Jonathan E Kolitz, Joseph O Moore, Geoffrey L Uy, Wendy Stock, Andrew J Carroll, John C. Byrd, Ann-Kathrin Eisfeld, Jatinder K. Lamba
Journal: Blood
Blood (2023) 142 (Supplement 1): 2954.
https://doi.org/10.1182/blood-2023-187361
Published: 2023
Journal Articles

Influence of Pre-Treatment Features and Therapy Choice By Physicians on Overall Survival in Older Adults with Acute Myeloid Leukemia: A Report from the Beat AML Master Trial

Uma M. Borate, Ying Huang, Rina Li Welkie, Ronan T. Swords, Elie Traer, Eytan M. Stein, Tara L Lin, Yazan F. Madanat, Prapti A. Patel, Robert H. Collins, Maria R. Baer, Vu H. Duong, William Blum, Martha Arellano, Wendy Stock, Olatoyosi Odenike, Robert L. Redner, Tibor J. Kovacsovics, Michael W. Deininger, Joshua F. Zeidner, Rebecca Olin, Catherine C. Smith, James M. Foran, Gary J. Schiller, Emily K Curran, Kristin L Koenig, Nyla A. Heerema, Timothy Chen, Molly Martycz, Mona Stefanos, Sonja Gullen Marcus, Leonard Rosenberg, Brian J. Druker, Ross L Levine, Amy Burd, Ashley Owen Yocum, Alice Mims, John C. Byrd
Journal: Blood
Blood (2023) 142 (Supplement 1): 4332.
https://doi.org/10.1182/blood-2023-181886
Published: 2023
Journal Articles

The Ancestry-Related Landscape of Long Non-Coding RNAs (LncRNAs) in Acute Myeloid Leukemia (AML) and Its Impact on Patient (Pt) Survival

Yazan Abu-Shihab, Deedra Nicolet, Krzysztof Mrózek, Andrew Stiff, Christopher J. Walker, Jill Buss, Alice Mims, Christopher C. Oakes, Karilyn T. Larkin, James S. Blachly, Andrew J Carroll, William Blum, Bayard L Powell, Jonathan E Kolitz, Richard M Stone, Geoffrey L Uy, Wendy Stock, Jennifer A. Woyach, John C. Byrd, Dimitrios Papaioannou, Ann-Kathrin Eisfeld, Kellie Archer
Journal: Blood
Blood (2023) 142 (Supplement 1): 722.
https://doi.org/10.1182/blood-2023-185030
Published: 2023
Journal Articles

North American Blastic Plasmacytoid Dendritic Cell Neoplasm Consortium: position on standards of care and areas of need

Naveen Pemmaraju, Hagop Kantarjian, Kendra Sweet, Eunice Wang, Jayastu Senapati, Nathaniel R. Wilson, Marina Konopleva, Arthur E. Frankel, Vikas Gupta, Ruben Mesa, Matthew Ulrickson, Edward Gorak, Sumeet Bhatia, Tulin Budak-Alpdogan, James Mason, Maria Teresa Garcia-Romero, Norma Lopez-Santiago, Gabriela Cesarman-Maus, Pankit Vachhani, Sangmin Lee, Vijaya Raj Bhatt, William Blum, Roland B. Walter, Dale Bixby, Ivana Gojo, Madeleine Duvic, Raajit K. Rampal, Marcos de Lima, James Foran, Amir T. Fathi, Aric Cameron Hall, Meagan A. Jacoby, Jeffrey Lancet, Gabriel Mannis, Anthony S. Stein, Alice Mims, David Rizzieri, Rebecca Olin, Alexander Perl, Gary Schiller, Paul Shami, Richard M. Stone, Stephen Strickland, Matthew J. Wieduwilt, Naval Daver, Farhad Ravandi, Sumithira Vasu, Monica Guzman, Gail J. Roboz, Joseph Khoury, Muzaffar Qazilbash, Phyu P. Aung, Branko Cuglievan, Yazan Madanat, Mohamed A. Kharfan-Dabaja, Anna Pawlowska, Justin Taylor, Martin Tallman, Prajwal Dhakal, Andrew A. Lane
Journal: Blood
Blood (2023) 141 (6): 567–578.
https://doi.org/10.1182/blood.2022017865
Published: 2023
Journal Articles

High Early Death Rates, Treatment Resistance and Short Survival of Black Adolescent and Young Adults (AYAs) with Acute Myeloid Leukemia (AML) (Alliance)

Karilyn Larkin, Deedra Nicolet, Ben Kelly, Krzysztof Mrózek, Katherine E Miller, Saranga Wijeratne, Stephanie LaHaye, Jessica Kohlschmidt, James S. Blachly, Alice S. Mims, Christopher J. Walker, Christopher C. Oakes, Shelley Orwick, Isaiah Boateng, Jill Buss, Adrienne Heyrosa, Andrew J Carroll, William Blum, Bayard L. Powell, Jonathan E Kolitz, Joseph O. Moore, Robert James Mayer, Richard A. Larson, Richard M. Stone, Electra D. Paskett, John C. Byrd, Elaine R. Mardis, Ann-Kathrin Eisfeld
Journal: Blood
Blood (2021) 138 (Supplement 1): 221.
https://doi.org/10.1182/blood-2021-151072
Published: 2021
Journal Articles

Comparative Outcomes and Molecular Response Predictors of IDH1/2-Mutated Adult Acute Myeloid Leukemia (AML) Patients (Pts) after Frontline Treatment with Intensive Induction Chemotherapy (IC), Targeted Inhibitors, or Hypomethylating Agents (HMA) (Alliance)

Uma Borate, Prapti A. Patel, Chetasi Talati, Jessica Kohlschmidt, Michael P. Ozga, Yazan F. Madanat, Luke Fletcher, Ravi Patel, Krzysztof Mrózek, Deedra Nicolet, Akriti G Jain, Virginia Olivia Volpe, Fei Yang, Richard D. Press, Daniel Jones, James S. Blachly, Christopher J. Walker, Andrew J Carroll, Guido Marcucci, Maria R. Baer, William Blum, Bayard L. Powell, Jonathan E Kolitz, Richard A. Larson, Richard M. Stone, John C. Byrd, Alice S. Mims, Kendra Sweet, Ann-Kathrin Eisfeld
Journal: Blood
Blood (2021) 138 (Supplement 1): 226.
https://doi.org/10.1182/blood-2021-152838
Published: 2021
Journal Articles

Ivosidenib (IVO) in Combination with Azacitidine (AZA) in Newly Diagnosed (ND) Older Patients with IDH1 R132-Mutated Acute Myeloid Leukemia (AML) Induces High Response Rates: A Phase 2 Sub-Study of the Beat AML Master Trial

Prapti Patel, Amy S. Ruppert, Uma Borate, Eytan M. Stein, Maria R. Baer, Wendy Stock, Tibor Kovacsovics, William Blum, Martha L. Arellano, Gary J. Schiller, Rebecca L. Olin, James M. Foran, Mark R. Litzow, Tara L. Lin, Matthew C. Foster, Robert L. Redner, Zeina Al-Mansour, Christopher R. Cogle, Michael M. Boyiadzis, Ronan Swords, Robert H. Collins, Jo-Anne Vergilio, Nyla A. Heerema, Leonard Rosenberg, Ashley Owen Yocum, Sonja Marcus, Timothy Chen, Franchesca Druggan, Mona Stefanos, Theophilus J Gana, Abigail B. Shoben, Brian J. Druker, Amy Burd, John C. Byrd, Ross L. Levine, Alice S. Mims
Journal: Blood
Blood (2021) 138 (Supplement 1): 875.
https://doi.org/10.1182/blood-2021-149115
Published: 2021
Journal Articles

Multi-Dimensional Analysis of Adult Acute Myeloid Leukemia (AML) Landscape Cross-Continents Reveals Age Associated Trends in Mutations and Outcomes

Monica Cusan, Karilyn Larkin, Deedra Nicolet, Vindi Jurinovic, Krzysztof Mrózek, Aarif M. N. Batcha, Maja Rothenberg-Thurley, Stephanie Schneider, Maria Cristina Sauerland, Dennis Görlich, Utz Krug, Wolfgang E. Berdel, Bernhard Josef Woermann, Wolfgang Hiddemann, Jan Braess, Karsten Spiekermann, Jessica Kohlschmidt, James S. Blachly, Alice S. Mims, Christopher J. Walker, Christopher C. Oakes, Shelley Orwick, Andrew J Carroll, William Blum, Bayard L. Powell, Jonathan E Kolitz, Joseph O. Moore, Robert James Mayer, Richard A. Larson, Richard M. Stone, John C. Byrd, Klaus H. Metzeler, Tobias Herold, Ann-Kathrin Eisfeld
Journal: Blood
Blood (2021) 138 (Supplement 1): 685.
https://doi.org/10.1182/blood-2021-153015
Published: 2021
Journal Articles

Gilteritinib (GILT) Monotherapy with Addition of Decitabine (DEC) in Non-Responders in Older Newly Diagnosed (ND) FLT3 Mutated Acute Myeloid Leukemia (AML) Patients Having High and Low Variant Allele Frequency (VAF): A Phase 2/1b Sub-Study of the Beat AML Master Trial

Elie Traer, Ying Huang, Alice S. Mims, Eytan M. Stein, Maria R. Baer, Wendy Stock, Tibor Kovacsovics, William Blum, Martha L. Arellano, Gary J. Schiller, Rebecca L. Olin, James M. Foran, Mark R. Litzow, Tara L. Lin, Prapti Patel, Matthew C. Foster, Robert L. Redner, Zeina Al-Mansour, Christopher R. Cogle, Michael M. Boyiadzis, Ronan Swords, Robert H. Collins, Jo-Anne Vergilio, Nyla A. Heerema, Leonard Rosenberg, Ashley O. Yocum, Sonja Marcus, Timothy Chen, Franchesca Druggan, Mona Stefanos, Theophilus J Gana, Abigail B. Shoben, Brian J. Druker, Amy Burd, John C. Byrd, Ross L. Levine, Uma Borate
Journal: Blood
Blood (2021) 138 (Supplement 1): 1277.
https://doi.org/10.1182/blood-2021-148207
Published: 2021
Journal Articles

Social Deprivation Independently Predicts Survival in Younger Patients with Acute Myeloid Leukemia (Alliance)

Melanie T Rebechi, Jessica Kohlschmidt, Krzysztof Mrózek, Deedra Nicolet, Alice S. Mims, James S. Blachly, Shelley Orwick, William Blum, Bayard L. Powell, Geoffrey L. Uy, Richard M. Stone, John C. Byrd, Electra D. Paskett, Jesse Plascak, Ann-Kathrin Eisfeld
Journal: Blood
Blood (2021) 138 (Supplement 1): 1983.
https://doi.org/10.1182/blood-2021-149647
Published: 2021
Journal Articles

Barriers to Evidence-Based Treatment Decision-Making in Acute Myeloid Leukemia: A Quality Improvement Initiative Across Community Oncology Practices

Joshua F. Zeidner, William Blum, Amir T. Fathi, Daniel A. Pollyea, Megan M. Stephan, Jeffrey D Carter, Cherilyn Heggen
Journal: Blood
Blood (2021) 138 (Supplement 1): 3016.
https://doi.org/10.1182/blood-2021-148638
Published: 2021
Journal Articles

Epigenetic Phenocopying Expands Molecular Risk Assessment in Acute Myeloid Leukemia (Alliance)

Brian Giacopelli, Salma Abdelbaky, Kyoko Yamaguchi, Jessica Kohlschmidt, Krzysztof Mrózek, Ada C Cleary, Yue-zhong Wu, Shelley Orwick, Deedra Nicolet, Kevin R Coombes, James S. Blachly, Bayard L. Powell, Jonathan E Kolitz, William Blum, Maria R. Baer, Andrew J Carroll, Richard M. Stone, Ann-Kathrin Eisfeld, Clara D. Bloomfield, John C. Byrd, Christopher C. Oakes
Journal: Blood
Blood (2021) 138 (Supplement 1): 803.
https://doi.org/10.1182/blood-2021-147652
Published: 2021