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Amelia Langston
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Journal Articles

High incidence of impaired graft function after allogeneic HSCT for myelofibrosis, and successful utilization of stem cell boost

Free
Maria Leon-Camarena, Leah Philips, Joseph Rimando, Colin Vale, Anthony Hunter, Michael Hochman, Amelia Langston, William Blum, Edmund Waller
Journal: Blood
Blood (2025) 146 (Supplement 1): 6394.
https://doi.org/10.1182/blood-2025-6394
Published: 2025
Journal Articles

T cell receptor costimulation blockade effectively prevents acute graft versus host disease without reducing the size or diversity of the T cell immune repertoire

Free
Chiara Wychera, Alexandre Albanese, Steven Siegel, Joseph Schmalz, Stephanie Bien, Brandi Bratrude, Kayla Betz, Lev Gorfinkel, Lorenzo Cagnin, Paul Keskula, Bruce Blazar, Muna Qayed, John Horan, Amelia Langston, Benjamin Watkins, Leslie Kean
Journal: Blood
Blood (2025) 146 (Supplement 1): 819.
https://doi.org/10.1182/blood-2025-819
Published: 2025
Journal Articles

Discovery of the transcription factor ZNF683/hobit as a central regulator of pathogenic T cell proliferation in acute gvhd

Free
Alexandre Albanese, Edward Chen, Yvonne Suessmuth, Jiayi Dong, James Kaminski, Lev Gorfinkel, Ally Eran, Jillian Zavistaski, Lorenzo Cagnin, Paul Keskula, Brandi Bratrude, Kayla Betz, Elham Rayzan, Muna Qayed, John Horan, Amelia Langston, Benjamin Watkins, Bruce Blazar, Leslie Kean
Journal: Blood
Blood (2025) 146 (Supplement 1): 275.
https://doi.org/10.1182/blood-2025-275
Published: 2025
Journal Articles

Upfront therapy with allogeneic hematopoietic stem cell transplantation versus DNA methyltransferase inhibitors in patients with vexas syndrome: A comparative matched cohort efficacy analysis of 39 patients

Free
Saubia Fathima, Ali Alsugair, Kimberly Langer, Terra Lasho, Christy Finke, Mark Litzow, Aasiya Matin, Urshila Durani, Mehrdad Hefazi Torghabeh, William Hogan, Mithun Shah, Ronald Go, Gabriel Bartoo, Jade Kutzke, Kristen McCullough, Matthew J Koster, Kenneth Warrington, Kaaren Reichard, Horatiu Olteanu, Yael Kusne, Jeanne Palmer, Saurabh Chhabra, Mary Riwes, Joseph McGuirk, Elizabeth Krakow, Amelia Langston, Taxiarchis Kourelis, David Dingli, Mrinal Patnaik, Hassan Alkhateeb, Abhishek Mangaonkar
Journal: Blood
Blood (2025) 146 (Supplement 1): 981.
https://doi.org/10.1182/blood-2025-981
Published: 2025
Journal Articles

Pentostatin Low-Dose TBI Is an Effective Conditioning Regimen That Permits Donor Engraftment in Patients with High Co-Morbidities Undergoing the First Transplant or Prior to a Second Transplant

Free
Ani Gvajaia, Joseph Rimando, William Blum, Colin A. Vale, Cynthia R. Giver, Elaina L. Corbett, Kevin Hall, Kristina Murphy, Mary Jo Lechowicz, Michel Conn, Minal Surati, Muna Qayed, Amelia Langston, Edmund K. Waller
Journal: Blood
Blood (2024) 144 (Supplement 1): 7325.
https://doi.org/10.1182/blood-2024-211880
Published: 2024
Journal Articles

Randomized Phase II Trial of Dendritic Cell/AML Fusion Cell Vaccination Compared to Standard of Care Therapy in AML CR1

Free
Prateek Pophali, Giulia Cheloni, Richard M. Stone, Kai W Wucherpfennig, Aric C. Hall, Amir T. Fathi, Lina Bisharat, Emma K Logan, Yiwen Liu, Donna S. Neuberg, Malgorzata McMasters, Jessica Liegel, Jacqueline S. Garcia, Daniel J. DeAngelo, Michele Narcis, Dina Stroopinsky, Pavania Elavalakanar, Ioannis S Vlachos, Ilene A. Galinsky, Jason Pyrdol, Georges Chedid, Dimitra Karagkouni, Shivani Nanda, Kathrine S Rallis, Isabella Saldarriaga, Hazal Toros, Haitham Abdelhakim, Amelia Langston, Joseph P. McGuirk, Donald Kufe, David Avigan, Jacalyn Rosenblatt
Journal: Blood
Blood (2024) 144 (Supplement 1): 4256.
https://doi.org/10.1182/blood-2024-200876
Published: 2024
Journal Articles

Five-Year Outcomes of the “Abatacept Combined with a Calcineurin Inhibitor and Methotrexate for Graft Versus Host Disease (GVHD) Prophylaxis: A Randomized Controlled Trial” (‘ABA2‘)

Free
Lev Gorfinkel, Muna Qayed, Brandi Bratrude, Kayla Betz, Kyle Hebert, Sung W. Choi, Jeffrey Davis, Christine Duncan, Roger H. Giller, Michael S. Grimley, Andrew Harris, David A Jacobsohn, Nahal Lalefar, Nosha Farhadfar, Michael A. Pulsipher, Shalini Shenoy, Aleksandra Petrovic, Kirk R. Schultz, Gregory Yanik, Bruce R Blazar, John T. Horan, Amelia Langston, Leslie Kean, Benjamin Watkins
Journal: Blood
Blood (2024) 144 (Supplement 1): 3516.
https://doi.org/10.1182/blood-2024-205130
Published: 2024
Journal Articles

NGS MRD Negativity on Day 28 after Brexu Cel in Adults with R/R ALL Is Associated with Favorable Progression Free Survival

Free
Yannis K. Valtis, David Nemirovsky, Sean M. Devlin, Gregory W Roloff, Ibrahim Aldoss, Nikeshan Jeyakumar, Katharine Miller, Amy Zhang, Katherine C. Sutherland, Anjali S. Advani, Marlise R. Luskin, Evan C. Chen, Omer Jamy, Michael R. Grunwald, Ibrahim Muhsen, Noam E. Kopmar, Bhagirathbhai Dholaria, Simone E. Dekker, Jessica T. Leonard, George Yaghmour, Stephanie B. Tsai, Wendy Stock, Jozal Moore, Kristen M. O'Dwyer, Aaron C. Logan, Matthew P Connor, Noelle Frey, Evandro Bezerra, Sumithira Vasu, Kaitlyn C Dykes, Minoo Battiwalla, Chenyu Lin, Matthew Ulrickson, Ran Reshef, Ryan D. Cassaday, Laquisha C. Hill, Catherine J. Lee, Vamsi K. Kota, Jacob Boccucci, Joshua Sasine, Akil Merchant, Vinod Pullarkat, Amelia Langston, Talal Hilal, Rawan Faramand, Melhem M. Solh, Tamer Othman, Timothy E O'Connor, Navneet Majhail, Shabaz Malik, Luke Mountjoy, Rasmus T. Hoeg, Caspian H. Oliai, Vishal Gupta, Divya Koura, Muthu V. Kumaran, Marc Schwartz, Veronika Bachanova, Sean I. Tracy, Maria Odstrcil Bobillo, Abdullah Ladha, Clayton Jackson, Vivian Irrizary Gatell, Olalekan O. Oluwole, Michael Daunov, John Mathews, Paul Shaughnessy, Bijal D Shah, Lori Muffly, Jae H. Park
Journal: Blood
Blood (2024) 144 (Supplement 1): 4200.
https://doi.org/10.1182/blood-2024-201610
Published: 2024
Journal Articles

Intermediate Dose Post-Transplant Cyclophosphamide Is Associated with Faster Engraftment and Similar Other Outcomes When Compared with Full Dose Post-Transplant Cyclophosphamide Among Patients Undergoing Allogeneic Transplantation: A Single Center Retrospective Analysis

Free
Joseph Rimando, Michel Conn, William Blum, Jason T Romancik, Colin Vale, Amelia Langston, Edmund K. Waller, Kevin Hall
Journal: Blood
Blood (2024) 144 (Supplement 1): 3521.
https://doi.org/10.1182/blood-2024-198921
Published: 2024
Journal Articles

Clinical Features and Outcomes of Patients with T-Cell/Histiocyte-Rich Large B-Cell Lymphoma: A Single-Center Analysis

Free
Jason T Romancik, Katelin Baird, Angelo Thomas Marra, Amelia Langston, Pamela B. Allen, Jonathon B. Cohen, Jean L. Koff, Mary Jo Lechowicz, Jeffrey M. Switchenko, Kristie A. Blum
Journal: Blood
Blood (2024) 144 (Supplement 1): 1717.
https://doi.org/10.1182/blood-2024-211784
Published: 2024
Journal Articles

Efficacy and Safety of Brexucabtagene Autoleucel for Relapsed/Refractory B-Cell Acute Lymphoblastic Leukemia in Patients Aged 60 and Above

Free
Ibrahim Muhsen, Anjali S. Advani, Gregory W Roloff, Nikeshan Jeyakumar, Katharine Miller, Amy Zhang, Katherine C. Sutherland, Michael R. Grunwald, Vamsi K. Kota, Jacob Boccucci, Matthew Ulrickson, Joshua Sasine, Ibrahim Aldoss, Tamer Othman, Sumithira Vasu, Ran Reshef, Marlise R. Luskin, Evan C. Chen, Chenyu Lin, Amelia Langston, Ryan D. Cassaday, Noam E. Kopmar, Stephanie B. Tsai, Timothy E O'Connor, Talal Hilal, Rawan Faramand, Jae H. Park, Yannis K. Valtis, Melhem M. Solh, Evandro Bezerra, Jessica T. Leonard, Simone E. Dekker, Navneet Majhail, Minoo Battiwalla, Shahbaz A. Malik, John Mathews, Paul Shaughnessy, Luke Mountjoy, Rasmus T. Hoeg, Caspian H. Oliai, Vishal Gupta, Divya Koura, Kaitlyn C Dykes, Aaron C. Logan, Muthu V. Kumaran, Wendy Stock, Marc Schwartz, Veronika Bachanova, Sean Tracy, Kristen M. O'Dwyer, Jozal Moore, Catherine J. Lee, Maria Silvina Odstrcil Bobillo, Noelle Frey, Matthew P Connor, Omer Jamy, Michael Daunov, Abdullah Ladha, George Yaghmour, Clayton Jackson, Vivian Irrizary Gatell, Olalekan O. Oluwole, Bhagirathbhai Dholaria, Vinod Pullarkat, Akil Merchant, Bijal D Shah, Lori Muffly, LaQuisa Hill
Journal: Blood
Blood (2024) 144 (Supplement 1): 523.
https://doi.org/10.1182/blood-2024-210682
Published: 2024
Journal Articles

Abatacept for acute graft-versus-host disease prophylaxis after unrelated donor hematopoietic cell transplantation

Free
Clinical Trials & Observations
Leslie S. Kean, Linda J. Burns, Tzuyung D. Kou, Roxanne Kapikian, Karissa Lozenski, Amelia Langston, John T. Horan, Benjamin Watkins, Muna Qayed, Brandi Bratrude, Kayla Betz, Xiao-Ying Tang, Mei-Jie Zhang, Sean E. Connolly, Martin Polinsky, Brian Gavin, Andres Gomez-Caminero, Marcelo C. Pasquini
Journal: Blood
Blood (2024) 144 (17): 1834–1845.
https://doi.org/10.1182/blood.2023023660
Published: 2024
Includes: Supplemental data
Journal Articles

Higher abatacept exposure after transplant decreases acute GVHD risk without increasing adverse events

Free
Clinical Trials & Observations
Takuto Takahashi, Mahmoud Al-Kofahi, Mutaz Jaber, Brandi Bratrude, Kayla Betz, Yvonne Suessmuth, Alison Yu, Donna S. Neuberg, Sung W. Choi, Jeffrey Davis, Christine Duncan, Roger Giller, Michael Grimley, Andrew C. Harris, David Jacobsohn, Nahal Lalefar, Nosha Farhadfar, Michael A. Pulsipher, Shalini Shenoy, Aleksandra Petrovic, Kirk R. Schultz, Gregory A. Yanik, Bruce R. Blazar, John T. Horan, Benjamin Watkins, Amelia Langston, Muna Qayed, Leslie S. Kean
Journal: Blood
Blood (2023) 142 (8): 700–710.
https://doi.org/10.1182/blood.2023020035
Published: 2023
Includes: Supplemental data
Journal Articles

Effective treatment of low-risk acute GVHD with itacitinib monotherapy

Free
Clinical Trials & Observations
Aaron Etra, Alexandra Capellini, Amin Alousi, Monzr M. Al Malki, Hannah Choe, Zachariah DeFilipp, William J. Hogan, Carrie L. Kitko, Francis Ayuk, Janna Baez, Isha Gandhi, Stelios Kasikis, Sigrun Gleich, Elizabeth Hexner, Matthias Hoepting, Urvi Kapoor, Steven Kowalyk, Deukwoo Kwon, Amelia Langston, Marco Mielcarek, George Morales, Umut Özbek, Muna Qayed, Ran Reshef, Wolf Rösler, Nikolaos Spyrou, Rachel Young, Yi-Bin Chen, James L. M. Ferrara, John E. Levine
Journal: Blood
Blood (2023) 141 (5): 481–489.
https://doi.org/10.1182/blood.2022017442
Published: 2023
Includes: Supplemental data
Journal Articles

Effective Treatment of Low Risk Acute Gvhd with Itacitinib Monotherapy

Free
Alexandra Capellini, Aaron Etra, Amin M Alousi, Monzr M. Al Malki, Hannah Choe, Zachariah Defilipp, William J. Hogan, Carrie Lynn Kitko, Francis A. Ayuk, Janna Baez, Isha Gandhi, Stelios Kasikis, Sigrun Gleich, Elizabeth O. Hexner, Matthias Hoepting, Urvi Kapoor, Steven Kowalyk, Deukwoo Kwon, Amelia Langston, Marco Mielcarek, George Morales, Umut Ozbek, Muna Qayed, Ran Reshef, Wolf Roesler, Nikolaos Spyrou, Rachel Young, Yi-Bin Chen, James L.M. Ferrara, John E. Levine
Journal: Blood
Blood (2022) 140 (Supplement 1): 1867–1869.
https://doi.org/10.1182/blood-2022-156000
Published: 2022
Journal Articles

Abatacept for the Prevention of Gvhd in Pediatric and Adult Patients Receiving 7/8 HLA-Mismatched Unrelated Transplant for Hematologic Malignancies: A Real-World Analysis

Free
Sharmila Raghunandan, Lev Gorfinkel, Michael Graiser, Brandi Bratrude, Kayla Betz, Yvonne Suessmuth, Scott Gillespie, Adrianna Lynn Westbrook, Kirsten M. Williams, Michelle Schoettler, Amelia Langston, Leslie Kean, Muna Qayed, John T. Horan, Benjamin Watkins
Journal: Blood
Blood (2022) 140 (Supplement 1): 7653–7655.
https://doi.org/10.1182/blood-2022-163627
Published: 2022
Journal Articles

Early Breakthrough T Cell Proliferation Despite CNI/MTX Prophylaxis Is a Harbinger of Acute Gvhd (AGVHD) and Is Controlled By Abatacept: Mechanism of Success of the ABA2 Agvhd Prevention Trial

Free
Alexandre Albanese, Alal Eran, Yvonne Suessmuth, Kayla Betz, Brandi Bratrude, Paula Keskula, Lorenzo Cagnin, Amelia Langston, Muna Qayed, John T. Horan, Bruce R. Blazar, Benjamin Watkins, Leslie S. Kean
Journal: Blood
Blood (2022) 140 (Supplement 1): 274–275.
https://doi.org/10.1182/blood-2022-170693
Published: 2022
Journal Articles

Belumosudil for chronic graft-versus-host disease after 2 or more prior lines of therapy: the ROCKstar Study

Free
Clinical Trials & Observations
Corey Cutler, Stephanie J. Lee, Sally Arai, Marcello Rotta, Behyar Zoghi, Aleksandr Lazaryan, Aravind Ramakrishnan, Zachariah DeFilipp, Amandeep Salhotra, Wanxing Chai-Ho, Rohtesh Mehta, Trent Wang, Mukta Arora, Iskra Pusic, Ayman Saad, Nirav N. Shah, Sunil Abhyankar, Carlos Bachier, John Galvin, Annie Im, Amelia Langston, Jane Liesveld, Mark Juckett, Aaron Logan, Levanto Schachter, Asif Alavi, Dianna Howard, Harlan W. Waksal, John Ryan, David Eiznhamer, Sanjay K. Aggarwal, Jonathan Ieyoub, Olivier Schueller, Laurie Green, Zhongming Yang, Heidi Krenz, Madan Jagasia, Bruce R. Blazar, Steven Pavletic
Journal: Blood
Blood (2021) 138 (22): 2278–2289.
https://doi.org/10.1182/blood.2021012021
Published: 2021
Includes: Supplemental data
Journal Articles

Predicting Immune Pathology after Hematopoietic Stem Cell Transplant with Transcriptomics: Naïve CD4 T Cell Expansion at Day 100 Predicts Patients with De Novo Chronic Gvhd

Free
Ben Watkins, MD, James Kaminski, Muna Qayed, MDMSc, Kayla Betz, BS, Yvonne Suessmuth, PhD, Brandi Bratrude, Alison Yu, PhD, Victor Tkachev, PhD, Kathryn Pellegrini, Steven Bosinger, PhD, Bruce R. Blazar, MD, John T. Horan, MDMPH, Amelia Langston, MD, Leslie Kean, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 38–39.
https://doi.org/10.1182/blood-2020-139488
Published: 2020
Journal Articles

Evaluating Outcomes for Autologous Hematopoietic Cell Transplantation for Diffuse Large B-Cell Lymphoma in the CAR-T Era

Free
Pranav R Santapuram, Manali Rupji, MS, Michael Graiser, PhD, Edmund K. Waller, PhDMD, Kristie A. Blum, MD, Pamela B. Allen, MD MSc, Jean L. Koff, MD, Leonard Heffner, MD, Mary Jo Lechowicz, MD, Sagar Lonial, MD FACP, Jonathan L. Kaufman, MD, Craig C Hofmeister, MDMPH, Madhav V. Dhodapkar, MD, Ajay Nooka, MDMPH, William Blum, MD, Rebecca B. Klisovic, MD, Nisha Joseph, MD, Vikas A. Gupta, MD PhD, Amelia Langston, MD, Jonathon B. Cohen, MDMS
Journal: Blood
Blood (2020) 136 (Supplement 1): 20–21.
https://doi.org/10.1182/blood-2020-142110
Published: 2020