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Amelia Langston
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Journal Articles

Abatacept for acute graft-versus-host disease prophylaxis after unrelated donor hematopoietic cell transplantation

Clinical Trials & Observations
Leslie S. Kean, Linda J. Burns, Tzuyung D. Kou, Roxanne Kapikian, Karissa Lozenski, Amelia Langston, John T. Horan, Benjamin Watkins, Muna Qayed, Brandi Bratrude, Kayla Betz, Xiao-Ying Tang, Mei-Jie Zhang, Sean E. Connolly, Martin Polinsky, Brian Gavin, Andres Gomez-Caminero, Marcelo C. Pasquini
Journal: Blood
Blood (2024) 144 (17): 1834–1845.
https://doi.org/10.1182/blood.2023023660
Published: 2024
Includes: Supplemental data
Journal Articles

Higher abatacept exposure after transplant decreases acute GVHD risk without increasing adverse events

Clinical Trials & Observations
Takuto Takahashi, Mahmoud Al-Kofahi, Mutaz Jaber, Brandi Bratrude, Kayla Betz, Yvonne Suessmuth, Alison Yu, Donna S. Neuberg, Sung W. Choi, Jeffrey Davis, Christine Duncan, Roger Giller, Michael Grimley, Andrew C. Harris, David Jacobsohn, Nahal Lalefar, Nosha Farhadfar, Michael A. Pulsipher, Shalini Shenoy, Aleksandra Petrovic, Kirk R. Schultz, Gregory A. Yanik, Bruce R. Blazar, John T. Horan, Benjamin Watkins, Amelia Langston, Muna Qayed, Leslie S. Kean
Journal: Blood
Blood (2023) 142 (8): 700–710.
https://doi.org/10.1182/blood.2023020035
Published: 2023
Includes: Supplemental data
Journal Articles

Effective treatment of low-risk acute GVHD with itacitinib monotherapy

Clinical Trials & Observations
Aaron Etra, Alexandra Capellini, Amin Alousi, Monzr M. Al Malki, Hannah Choe, Zachariah DeFilipp, William J. Hogan, Carrie L. Kitko, Francis Ayuk, Janna Baez, Isha Gandhi, Stelios Kasikis, Sigrun Gleich, Elizabeth Hexner, Matthias Hoepting, Urvi Kapoor, Steven Kowalyk, Deukwoo Kwon, Amelia Langston, Marco Mielcarek, George Morales, Umut Özbek, Muna Qayed, Ran Reshef, Wolf Rösler, Nikolaos Spyrou, Rachel Young, Yi-Bin Chen, James L. M. Ferrara, John E. Levine
Journal: Blood
Blood (2023) 141 (5): 481–489.
https://doi.org/10.1182/blood.2022017442
Published: 2023
Includes: Supplemental data
Journal Articles

Early Breakthrough T Cell Proliferation Despite CNI/MTX Prophylaxis Is a Harbinger of Acute Gvhd (AGVHD) and Is Controlled By Abatacept: Mechanism of Success of the ABA2 Agvhd Prevention Trial

Alexandre Albanese, Alal Eran, Yvonne Suessmuth, Kayla Betz, Brandi Bratrude, Paula Keskula, Lorenzo Cagnin, Amelia Langston, Muna Qayed, John T. Horan, Bruce R. Blazar, Benjamin Watkins, Leslie S. Kean
Journal: Blood
Blood (2022) 140 (Supplement 1): 274–275.
https://doi.org/10.1182/blood-2022-170693
Published: 2022
Journal Articles

Effective Treatment of Low Risk Acute Gvhd with Itacitinib Monotherapy

Alexandra Capellini, Aaron Etra, Amin M Alousi, Monzr M. Al Malki, Hannah Choe, Zachariah Defilipp, William J. Hogan, Carrie Lynn Kitko, Francis A. Ayuk, Janna Baez, Isha Gandhi, Stelios Kasikis, Sigrun Gleich, Elizabeth O. Hexner, Matthias Hoepting, Urvi Kapoor, Steven Kowalyk, Deukwoo Kwon, Amelia Langston, Marco Mielcarek, George Morales, Umut Ozbek, Muna Qayed, Ran Reshef, Wolf Roesler, Nikolaos Spyrou, Rachel Young, Yi-Bin Chen, James L.M. Ferrara, John E. Levine
Journal: Blood
Blood (2022) 140 (Supplement 1): 1867–1869.
https://doi.org/10.1182/blood-2022-156000
Published: 2022
Journal Articles

Abatacept for the Prevention of Gvhd in Pediatric and Adult Patients Receiving 7/8 HLA-Mismatched Unrelated Transplant for Hematologic Malignancies: A Real-World Analysis

Sharmila Raghunandan, Lev Gorfinkel, Michael Graiser, Brandi Bratrude, Kayla Betz, Yvonne Suessmuth, Scott Gillespie, Adrianna Lynn Westbrook, Kirsten M. Williams, Michelle Schoettler, Amelia Langston, Leslie Kean, Muna Qayed, John T. Horan, Benjamin Watkins
Journal: Blood
Blood (2022) 140 (Supplement 1): 7653–7655.
https://doi.org/10.1182/blood-2022-163627
Published: 2022
Journal Articles

Belumosudil for chronic graft-versus-host disease after 2 or more prior lines of therapy: the ROCKstar Study

Clinical Trials & Observations
Corey Cutler, Stephanie J. Lee, Sally Arai, Marcello Rotta, Behyar Zoghi, Aleksandr Lazaryan, Aravind Ramakrishnan, Zachariah DeFilipp, Amandeep Salhotra, Wanxing Chai-Ho, Rohtesh Mehta, Trent Wang, Mukta Arora, Iskra Pusic, Ayman Saad, Nirav N. Shah, Sunil Abhyankar, Carlos Bachier, John Galvin, Annie Im, Amelia Langston, Jane Liesveld, Mark Juckett, Aaron Logan, Levanto Schachter, Asif Alavi, Dianna Howard, Harlan W. Waksal, John Ryan, David Eiznhamer, Sanjay K. Aggarwal, Jonathan Ieyoub, Olivier Schueller, Laurie Green, Zhongming Yang, Heidi Krenz, Madan Jagasia, Bruce R. Blazar, Steven Pavletic
Journal: Blood
Blood (2021) 138 (22): 2278–2289.
https://doi.org/10.1182/blood.2021012021
Published: 2021
Includes: Supplemental data
Journal Articles

Predicting Immune Pathology after Hematopoietic Stem Cell Transplant with Transcriptomics: Naïve CD4 T Cell Expansion at Day 100 Predicts Patients with De Novo Chronic Gvhd

Ben Watkins, MD, James Kaminski, Muna Qayed, MDMSc, Kayla Betz, BS, Yvonne Suessmuth, PhD, Brandi Bratrude, Alison Yu, PhD, Victor Tkachev, PhD, Kathryn Pellegrini, Steven Bosinger, PhD, Bruce R. Blazar, MD, John T. Horan, MDMPH, Amelia Langston, MD, Leslie Kean, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 38–39.
https://doi.org/10.1182/blood-2020-139488
Published: 2020
Journal Articles

Evaluating Outcomes for Autologous Hematopoietic Cell Transplantation for Diffuse Large B-Cell Lymphoma in the CAR-T Era

Pranav R Santapuram, Manali Rupji, MS, Michael Graiser, PhD, Edmund K. Waller, PhDMD, Kristie A. Blum, MD, Pamela B. Allen, MD MSc, Jean L. Koff, MD, Leonard Heffner, MD, Mary Jo Lechowicz, MD, Sagar Lonial, MD FACP, Jonathan L. Kaufman, MD, Craig C Hofmeister, MDMPH, Madhav V. Dhodapkar, MD, Ajay Nooka, MDMPH, William Blum, MD, Rebecca B. Klisovic, MD, Nisha Joseph, MD, Vikas A. Gupta, MD PhD, Amelia Langston, MD, Jonathon B. Cohen, MDMS
Journal: Blood
Blood (2020) 136 (Supplement 1): 20–21.
https://doi.org/10.1182/blood-2020-142110
Published: 2020
Journal Articles

Potent Interaction between CMV Reactivation and Gvhd: Immunologic Evidence for Blunting of CMV-Driven Immune Reconstitution in the Setting of Gvhd

Yvonne Suessmuth, PhD, Kayla Betz, BS, Alison Yu, PhD, Brandi Bratrude, Benjamin Watkins, MD, Muna Qayed, MDMSc, John T. Horan, MDMPH, Leslie Kean, MD PhD, Amelia Langston, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 50.
https://doi.org/10.1182/blood-2020-141856
Published: 2020
Journal Articles

Transcriptomic Analysis of CD4+ T Cell Dysfunction during Gvhd: Evidence for Profound Reprograming of T Cell Signaling during Acute Gvhd That Is Controlled during CD28:CD80/86 Costimulation Blockade with Abatacept

Benjamin Watkins, Yvonne Suessmuth, Kayla Betz, BS, Alison Yu, PhD, Brandi Bratrude, Muna Qayed, MD MSc, Kathryn Pellegrini, Steven Bosinger, Amelia Langston, MD, John T. Horan, MDMPH, Bruce R. Blazar, MD, Leslie Kean, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 596.
https://doi.org/10.1182/blood-2019-131955
Published: 2019
Journal Articles

Pentotstatin/TBI Conditioning Is Well-Tolerated and Permits Engraftment of a Second Allogeneic Stem Cell Transplant Following Primary or Secondary Rejection of an Allogeneic Hematopoietic Stem Graft

Ani Gvajaia, MD, Amelia Langston, MD, Natia Esiashvil, MD, Michael Graiser, PhD, Kelly Valla, PharmD, Edmund K. Waller, PhDMD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5657.
https://doi.org/10.1182/blood-2019-122467
Published: 2019
Journal Articles

Outcomes of Elderly Patients Undergoing Allogeneic Transplantation for Acute Myeloid Leukemia with Fludarabine/Melphalan or Fludarabine/TBI Conditioning Regimen

Ashley C Woods, MD, Nisha Joseph, MD, Manali Rupji, MS, Yuan Liu, PhD, Amelia Langston, MD, Edmund K. Waller, PhDMD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3331.
https://doi.org/10.1182/blood-2019-130581
Published: 2019
Journal Articles

Safety and Efficacy of Evomela™ in Myeloma Autotransplants

Kimberly Amelsberg, Nisha Joseph, MD, Amelia Langston, MD, Jonathan L Kaufman, MD, Craig C Hofmeister, MD MPH, Edmund K. Waller, MD, Michael Graiser, PhD, Robin Larocco, Leonard Heffner, MD, Madhav V Dhodapkar, MD, Sagar Lonial, MD, Ajay K Nooka, MD MPH
Journal: Blood
Blood (2018) 132 (Supplement 1): 3446.
https://doi.org/10.1182/blood-2018-99-119730
Published: 2018
Journal Articles

Evaluation of All Cause of Death after High Dose Chemotherapy and Autologous Stem Cell Transplant in Hodgkin Lymphoma and Non-Hodgkin Lymphoma

Danielle Roberts, PA-C, Subir Goyal, MPH, MBBS, Zhao Chang, PhD, Christopher R Flowers, MD MS, Mary Jo Lechowicz, MD, Amelia Langston, MD, Edmund K. Waller, MD, Sagar Lonial, MD, Pamela Allen, MD MSc, Kristie A. Blum, MD, Jean L. Koff, MD, Jonathan L Kaufman, MD, Ajay K Nooka, MD MPH, Michael Graiser, PhD, Cecilia Rosand, PA-C, Alexandra Palmer, NP-C, Nassoma Bumpers, PA-C, Catherine Fenner, PA-C, Joel O Andrews, PA-C, Caleb J. Raine, MSPAS, PA-C, Jonathon B. Cohen, MD MS
Journal: Blood
Blood (2018) 132 (Supplement 1): 2157.
https://doi.org/10.1182/blood-2018-99-118896
Published: 2018
Journal Articles

The Impact of a Physical Activity Intervention Can be Accurately Assessed By Smart Watches in Patients Completing Autologous Stem Cell Transplantation for Lymphoma or Multiple Myeloma: Results of a Feasibility Study

Andrew Ip, MD, Michael C Churnetski, BS, Oscar Calzada, BS, Andres Chang, MD PhD, Yuan Liu, PhD, Nassoma Bumpers, PA-C, Deborah Leeson, Ernestine Mahar, BSc, Iraj Hesaroieh, Maria Crain, RN, Ajay K Nooka, MD MPH, Jean L. Koff, MD, Craig C Hofmeister, MD MPH, Vikas A. Gupta, MD PhD, Pamela Allen, MD MSc, Mary Jo Lechowicz, MD, Jonathan L Kaufman, MD, Kristie A. Blum, MD, Sagar Lonial, MD, Amelia Langston, MD, Edmund K. Waller, MD, Christopher R Flowers, MD MS, Jonathon B. Cohen, MD MS
Journal: Blood
Blood (2018) 132 (Supplement 1): 5911.
https://doi.org/10.1182/blood-2018-99-119757
Published: 2018
Journal Articles

Improving Outcomes in Elderly Acute Promyelocytic Leukemia Patients in the Real World: A Personalized Treatment Approach Along with Expert Support Might Reduce Early Deaths

Vamsi Kota, MBBS, Martha L. Arellano, MD, Prachi Kharkhanis, Sheldon Bolds, Catherine R. Caprara, MSN, NP, Kathryn Sarah Simon, PA-C, Stephanie Debragga, Manila Gaddh, MD, Leon Bernal-Mizrachi, MD, Leonard Heffner, MD, Elliott F. Winton, MD, Morgan L. McLemore, MD, Amelia Langston, MD, Zaid Al-Kadhimi, MD, Asad Bashey, MD PhD, Robert K. Stuart, MD, Asim Pati, MD, Jonathan M. Gerber, MD, Michael Richard Grunwald, MD, Kyle Bradley, MD MS, Jose Tongol, MD, Mohamed El-Geneidy, Amber Clemmons, Anand Jillella, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 5667.
https://doi.org/10.1182/blood.V130.Suppl_1.5667.5667
Published: 2017
Journal Articles

Assessing Individual Comorbidities in Elderly Non-Hodgkin Lymphoma Patients Undergoing Autologous Stem Cell Transplant — Obesity Associated with Inferior Outcomes

Andrew Ip, MD, Jeffrey M. Switchenko, PhD MS, Michael Graiser, Jean L. Koff, MD, Vikas A. Gupta, MD PhD, Ajay K. Nooka, MDMPH, Zaid Al-Kadhimi, MD, Mary Jo Lechowicz, MD, Jonathan L. Kaufman, MD, Sagar Lonial, MD, Edmund K. Waller, MD, Amelia Langston, MD, Christopher Flowers, MD, Jonathon B Cohen, MDMS
Journal: Blood
Blood (2017) 130 (Supplement 1): 5516.
https://doi.org/10.1182/blood.V130.Suppl_1.5516.5516
Published: 2017
Journal Articles

T Cell Costimulation Blockade with Abatacept Nearly Eliminates Early Severe Acute Graft Versus Host Disease after HLA-Mismatched (7/8 HLA Matched) Unrelated Donor Transplant, with a Favorable Impact on Disease-Free and Overall Survival

Ben Watkins, MD, Muna Qayed, MDMSc, Brandi Bratrude, Kayla Betz, Melanie Brown, BS, James Rhodes, Shauna Sinclair, Yvonne Suessmuth, Alison Yu, PhD, Kyle Hebert, Marcelo C. Pasquini, MDMS, Sung W. Choi, MD MS, Jeffrey Davis, Christine Duncan, MD MSc, Roger Giller, MD, Michael Grimley, MD, Andrew C Harris, MD, David A. Jacobsohn, MD, Nahal Lalefar, Maxim Norkin, MD, Michael A Pulsipher, MD, Shalini Shenoy, MD, Bruce Blazar, MD, Amelia Langston, MD, John T Horan, MD, Leslie Kean, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 212.
https://doi.org/10.1182/blood.V130.Suppl_1.212.212
Published: 2017
Journal Articles

A Multi-Center Prospective Study Utilizing a Simplified Treatment Algorithm Complemented By Expert Support Decreases Induction Mortality and Improves Survival in Acute Promyelocytic Leukemia (APL). Results of the APL Trial in Georgia, South Carolina and Neighboring States

Anand Jillella, MD, Prachi Karkhanis, Rashmi Sharma, Sheldon Bolds, Anima Shrestha, Kaitlin Sitchenko, Veeraen Jonnalagadda, Manila Gaddh, MD, Leon Bernal-Mizrachi, MD, Leonard T. Heffner, MD, Elliott F. Winton, MD, Morgan L. McLemore, MD, Amelia Langston, MD, Jacques Galipeau, MD, Imre Bodó, MD PhD, Zaid Al-Kadhimi, MD, Asad Bashey, MD PhD, Robert K. Stuart, MD, Sarah I. Vidito, DO, Asim Pati, MD, Jonathan M. Gerber, MD, Michael R. Grunwald, MD, Kyle T. Bradley, MD MS, Jose Tongol, MD, Mohamed El-Geneidy, Hanna Jean Khoury, MD, Martha Arellano, MD, Vamsi Kota, MD
Journal: Blood
Blood (2016) 128 (22): 2793.
https://doi.org/10.1182/blood.V128.22.2793.2793
Published: 2016