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Brandi Bratrude
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Journal Articles

Abatacept for acute graft-versus-host disease prophylaxis after unrelated donor hematopoietic cell transplantation

Clinical Trials & Observations
Leslie S. Kean, Linda J. Burns, Tzuyung D. Kou, Roxanne Kapikian, Karissa Lozenski, Amelia Langston, John T. Horan, Benjamin Watkins, Muna Qayed, Brandi Bratrude, Kayla Betz, Xiao-Ying Tang, Mei-Jie Zhang, Sean E. Connolly, Martin Polinsky, Brian Gavin, Andres Gomez-Caminero, Marcelo C. Pasquini
Journal: Blood
Blood (2024) 144 (17): 1834–1845.
https://doi.org/10.1182/blood.2023023660
Published: 2024
Includes: Supplemental data
Journal Articles

Higher abatacept exposure after transplant decreases acute GVHD risk without increasing adverse events

Clinical Trials & Observations
Takuto Takahashi, Mahmoud Al-Kofahi, Mutaz Jaber, Brandi Bratrude, Kayla Betz, Yvonne Suessmuth, Alison Yu, Donna S. Neuberg, Sung W. Choi, Jeffrey Davis, Christine Duncan, Roger Giller, Michael Grimley, Andrew C. Harris, David Jacobsohn, Nahal Lalefar, Nosha Farhadfar, Michael A. Pulsipher, Shalini Shenoy, Aleksandra Petrovic, Kirk R. Schultz, Gregory A. Yanik, Bruce R. Blazar, John T. Horan, Benjamin Watkins, Amelia Langston, Muna Qayed, Leslie S. Kean
Journal: Blood
Blood (2023) 142 (8): 700–710.
https://doi.org/10.1182/blood.2023020035
Published: 2023
Includes: Supplemental data
Journal Articles

Early Breakthrough T Cell Proliferation Despite CNI/MTX Prophylaxis Is a Harbinger of Acute Gvhd (AGVHD) and Is Controlled By Abatacept: Mechanism of Success of the ABA2 Agvhd Prevention Trial

Alexandre Albanese, Alal Eran, Yvonne Suessmuth, Kayla Betz, Brandi Bratrude, Paula Keskula, Lorenzo Cagnin, Amelia Langston, Muna Qayed, John T. Horan, Bruce R. Blazar, Benjamin Watkins, Leslie S. Kean
Journal: Blood
Blood (2022) 140 (Supplement 1): 274–275.
https://doi.org/10.1182/blood-2022-170693
Published: 2022
Journal Articles

Abatacept for the Prevention of Gvhd in Pediatric and Adult Patients Receiving 7/8 HLA-Mismatched Unrelated Transplant for Hematologic Malignancies: A Real-World Analysis

Sharmila Raghunandan, Lev Gorfinkel, Michael Graiser, Brandi Bratrude, Kayla Betz, Yvonne Suessmuth, Scott Gillespie, Adrianna Lynn Westbrook, Kirsten M. Williams, Michelle Schoettler, Amelia Langston, Leslie Kean, Muna Qayed, John T. Horan, Benjamin Watkins
Journal: Blood
Blood (2022) 140 (Supplement 1): 7653–7655.
https://doi.org/10.1182/blood-2022-163627
Published: 2022
Journal Articles

MI-Immune/1801: Lessons from an Ongoing, Multi-Center Trial Involving Biospecimen Collection for Prospective Microbiome and Immune Profiling in Patients Undergoing Reduced Intensity Conditioning Allogeneic HCT

Erin Brooks, Ashley Spahn, Stephanie Waldvogel, Alan Howard, Merav Bar, Brandi Bratrude, Saurabh Chhabra, William Clark, Suman Ranjan Das, Mary M. Horowitz, Robert R. Jenq, Richard J. Jones, John E. Levine, Brent R. Logan, Hemant S. Murthy, Armin Rashidi, Marcie L. Riches, Mary Mansour Riwes, Karamjeet S. Sandhu, Anthony D. Sung, Monzr M. Al Malki, Lyndsey Runaas, Hany Elmariah, Andrew R. Rezvani, Mahasweta Gooptu, Javier Bolaños-Meade, Shernan G Holtan, Wael Saber, Mehdi Hamadani, Leslie S Kean, Miguel-Angel Perales, Ami S. Bhatt
Journal: Blood
Blood (2021) 138 (Supplement 1): 2955.
https://doi.org/10.1182/blood-2021-149313
Published: 2021
Journal Articles

Predicting Immune Pathology after Hematopoietic Stem Cell Transplant with Transcriptomics: Naïve CD4 T Cell Expansion at Day 100 Predicts Patients with De Novo Chronic Gvhd

Ben Watkins, MD, James Kaminski, Muna Qayed, MDMSc, Kayla Betz, BS, Yvonne Suessmuth, PhD, Brandi Bratrude, Alison Yu, PhD, Victor Tkachev, PhD, Kathryn Pellegrini, Steven Bosinger, PhD, Bruce R. Blazar, MD, John T. Horan, MDMPH, Amelia Langston, MD, Leslie Kean, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 38–39.
https://doi.org/10.1182/blood-2020-139488
Published: 2020
Journal Articles

Potent Interaction between CMV Reactivation and Gvhd: Immunologic Evidence for Blunting of CMV-Driven Immune Reconstitution in the Setting of Gvhd

Yvonne Suessmuth, PhD, Kayla Betz, BS, Alison Yu, PhD, Brandi Bratrude, Benjamin Watkins, MD, Muna Qayed, MDMSc, John T. Horan, MDMPH, Leslie Kean, MD PhD, Amelia Langston, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 50.
https://doi.org/10.1182/blood-2020-141856
Published: 2020
Journal Articles

Transcriptomic Analysis of CD4+ T Cell Dysfunction during Gvhd: Evidence for Profound Reprograming of T Cell Signaling during Acute Gvhd That Is Controlled during CD28:CD80/86 Costimulation Blockade with Abatacept

Benjamin Watkins, Yvonne Suessmuth, Kayla Betz, BS, Alison Yu, PhD, Brandi Bratrude, Muna Qayed, MD MSc, Kathryn Pellegrini, Steven Bosinger, Amelia Langston, MD, John T. Horan, MDMPH, Bruce R. Blazar, MD, Leslie Kean, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 596.
https://doi.org/10.1182/blood-2019-131955
Published: 2019
Journal Articles

T Cell Costimulation Blockade with Abatacept Nearly Eliminates Early Severe Acute Graft Versus Host Disease after HLA-Mismatched (7/8 HLA Matched) Unrelated Donor Transplant, with a Favorable Impact on Disease-Free and Overall Survival

Ben Watkins, MD, Muna Qayed, MDMSc, Brandi Bratrude, Kayla Betz, Melanie Brown, BS, James Rhodes, Shauna Sinclair, Yvonne Suessmuth, Alison Yu, PhD, Kyle Hebert, Marcelo C. Pasquini, MDMS, Sung W. Choi, MD MS, Jeffrey Davis, Christine Duncan, MD MSc, Roger Giller, MD, Michael Grimley, MD, Andrew C Harris, MD, David A. Jacobsohn, MD, Nahal Lalefar, Maxim Norkin, MD, Michael A Pulsipher, MD, Shalini Shenoy, MD, Bruce Blazar, MD, Amelia Langston, MD, John T Horan, MD, Leslie Kean, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 212.
https://doi.org/10.1182/blood.V130.Suppl_1.212.212
Published: 2017